Exploration of treatment burden through examination of workload and patient capacity during transition onto kidney replacement therapy: a systematic review of qualitative research by Catrin Jones, Ross Cairns, Heather Walker, Silje Welsh, Benjamin Edgar, Karen Stevenson, Bhautesh D. Jani, Patrick B. Mark, David Kingsmore, Katie I. Gallacher

“…The aim of this review is to examine the experience of healthcare workload and the factors that affect capacity to meet that workload for people transitioning onto KRT for the first time, using a framework synthesis of published literature informed by normalisation process theory (NPT) and theory of patient capacity (TPC). Methods Medline, Scopus and CINAHL were systematically searched with manual citation and reference searching. …”
Get full text

Comparison of Healthcare Encounters and Drug Persistence in Patients With Pulmonary Arterial Hypertension Receiving Oral Selexipag, Inhaled Iloprost, or Parenteral Treprostinil: A... by Ci Song, Peter Kunovszki, Amélie Beaudet

“…**Objectives:** To conduct retrospective database analyses to describe characteristics of patients with PAH initiating therapy with these agents and compare the rate and risk of healthcare facility encounters and drug persistence. **Methods:** Data were obtained from the Optum™ Clinformatics® Data Mart and Truven™ Health Analytics® MarketScan® Commercial Claims and Encounters databases from July 1, 2008, to September 30, 2020 (Optum™), or October 31, 2020 (Truven™). …”
Get full text

CircHIPK2 recruits SRSF1 to increase TXNIP mRNA stability and promotes autophagy-dependent ferroptosis and apoptosis in myocardial ischemia-reperfusion injury by Zhu Zhang, Jinqi Hao, Qinghong Qiao, Junting Song, Yanqin Yu

“…In this study, the role and mechanism of circHIPK2 in MIRI were evaluated. Methods Human cardiac myocytes (HCM) were cultured under Hypoxia/Reoxygenation (H/R) condition to establish a MIRI model in vitro. …”
Get full text

The financial toxicity of cancer: unveiling global burden and risk factors – a systematic review and meta-analysis by Addisu Getie, Alemu Birara Zemariam, Befkad Derese Tilahun, Ribka Nigatu Haile, Tegene Atamenta Kitaw, Molla Azmeraw Bizuayehu

“…This systematic review and meta-analysis aims to provide a comprehensive overview of cancer-related financial toxicity and identify key risk factors contributing to this burden.Methods We conducted a systematic review and meta-analysis, searching databases like Medline, Web of Science, PubMed, Scopus, International Scientific Indexing and Google Scholar for peer-reviewed observational studies. …”
Get full text

Sex-related Anthropometrics in a Lower-Body Mobility Assessment Among Professional Soccer Athletes by Corbin A. Hedt, Jessica T. Le, Tyler Heimdal, Justin Vickery, Erin Orozco, Patrick C. McCulloch, Bradley S. Lambert

“… # Study Design Cross Sectional # Methods During pre-season assessments, athletes from two professional soccer clubs were recruited and underwent body composition and skeletal dimension analysis via dual-energy X-ray absorptiometry (DEXA) scans. …”
Get full text

3D-augmentation of 2D ultrasound for appendicitis diagnosis: A cross-sectional pilot study by Rebecca G. Theophanous, Elias Jaffa, Matthew R. Morgan, Carl D. Herickhoff, Erica Peethumnongsin, Joao Ricardo Nickenig Vissoci, Joshua S. Broder

“…Objective: We hypothesized that bedside-performed 3DUS would be feasible, with rapid image acquisition times, and good image quality comparable to 2DUS and CT. Methods: We performed a cross-sectional pilot study on emergency department patients being evaluated for appendicitis. …”
Get full text

Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience) by I. Yu. Pirogova, N. B. Kovaleva, E. P. Patlusov, E. S. Radchenko

“…To estimate efficacy and safety of cepeginterferon-alpha 2b (cPEG-IFNα2b) and ribavirin combination for the treatment of chronic hepatitis C (CHC), to define necessity of IL-28V genetic polymorphism diagnostics, to estimate liver elastometry scores at the background of antiviral therapy. Material and methods. Overall 164 patients with hepatitis C viruses (HCV) genotypes 1, 2 and 3 in 4 medical centers received antiviral therapy. …”
Get full text

Relationships between Running Biomechanics, Hip Muscle Strength, and Running-Related Injury in Female Collegiate Cross-country Runners by Elena N. Venable, Lily A. Seynaeve, Scott T. Beale, Albert Gamez Jr., Antoinette Domingo, Michael D. Rosenthal, Mitchell J. Rauh

“… # Study Design Prospective observational cohort. # Methods Participants included twenty female NCAA collegiate XC runners from Southern California universities who competed in the 2019-20 intercollegiate season. …”
Get full text

Interdisciplinary Team Pilot to Reduce Time to Administration of Piperacillin/Tazobactam in the Emergency Department at a Veterans Affairs Medical Center by DiVittorio MM, Fisher T, Steadman B, Cone B, Elfessi Z

“…Factors that affect antibiotic administration time include the antibiotic dispensary location, best practice alerts in electronic medical records, and staff “huddles” to continuously reinforce the importance of antibiotics.Methods: At our Veterans Affairs Medical Center, we moved piperacillin/tazobactam from the central pharmacy to the emergency department automated dispensing cabinet. …”
Get full text

Network relationship between cognitive function and quality of life in community-dwelling older adults: an observational study from Beijing by Yitian Ye, Yichun Zhang, Jiaju Ren, Yanbo Zhu, Yanbo Zhu

“…ObjectiveThis observational study aims to comprehensively explore the network relationship and mechanism of action between cognitive function and quality of life among community-dwelling older adults aged 60 and above in Beijing.MethodsThe research encompassed a cohort of 323 older adults individuals residing in the community in Beijing. …”
Get full text

Paleozoic multi-stage magmatism in the Yuka terrane, North Qaidam orogenic belt: mantle modification, tectonic evolution, and geodynamic processes by Yibin Lin, Chengtao Yu, Shuyuan Chen, Sudong Shi, Sangjiancuo Luo, Junaid Khan

“…The detailed study of HP/UHP metamorphic rocks and intermediate-acid rocks has revealed the complete tectonic evolution of the North Qaidam Orogenic Belt (NQOB), from oceanic to continental subduction and subsequent exhumation. …”
Get full text

Association of only-child status and household pet ownership with attention-deficit/hyperactivity disorder among Chinese preschool children: a population-based study by Yuying Zhang, Shuangyan Qiu, Vivian Yawei Guo, Weiqing Chen, Xiaomei Han, Weikang Yang

“…BackgroundThe associations of only-child status and household pet ownership with the risk of attention-deficit/hyperactivity disorder (ADHD) are inconclusive, and the joint effects of only-child status and household pet ownership on ADHD have not been thoroughly investigated.MethodsA population-based study was conducted in 2021 involving preschool children aged 3–6 years attending kindergartens in Longhua District, Shenzhen, China. …”
Get full text

The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

“…**Objectives:** This study examined patient-reported survey data linked with Medicare claims to describe the burden of these vision-threatening retinal diseases (VTRDs) among Medicare beneficiaries. **Methods:** Medicare Current Beneficiary Survey data linked with Medicare Fee-for-Service claims data from 2006 to 2018 were used in a nationally representative retrospective pooled cross-sectional population-based comparison study. …”
Get full text

Acute effect of technique modification training on 180° change of direction performance and kinematics in adolescent male soccer players by Hayato Nakamura, Daichi Yamashita, Daichi Nishiumi, Naoto Nakaichi, Norikazu Hirose

“…This study investigated the acute effects of COD modification training on COD performance and kinematics in male adolescent soccer players.MethodsTwenty-nine male junior high school soccer players participated in this study and were divided into two groups: 16 players underwent 15-min COD technique modification training (COD group), while 13 players engaged in 15-min linear sprint training. …”
Get full text

The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia by Kai Shen, Chenlu Yang, Jie Huang, Xiao Shuai, Ting Niu, Hongbing Ma

“…Nevertheless, its clinical characteristics and impact on APL prognosis have yet to be elucidated.ObjectivesThe aim of this study was to describe the clinical characteristics of DS-related AKI in patients with APL and its impact on patient prognosis.MethodsThis was a retrospective study from a single center in a real-world setting. …”
Get full text

Out-of-field dose assessment for pencil beam scanning proton radiotherapy versus photon radiotherapy for breast cancer in pregnant women by Menke Weessies, Murillo Bellezzo, Britt J.P. Hupkens, Frank Verhaegen, Gloria Vilches-Freixas

“…This study compares out-of-field radiation doses between two treatment modalities: 6MV external photon radiotherapy (XRT) and pencil beam scanning proton-therapy (PBS-PRT) for breast cancer, including imaging, to evaluate PBS-PRT as a potential new treatment option. Materials and methods: For breast cancer involving lymph node levels 1–4 and the intramammary lymph nodes, treatment plans were created for XRT (with Flattening Filter (FF) and FF-Free (FFF)) and PBS-PRT, prescribing 15 × 2.67 Gy(RBE). …”
Get full text

Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis by Zhu L, Tian L, Li S, Huo L

“…This study aimed to explore the relationship between blood lipid levels and disease activity, and to evaluate the early predictive value of blood lipid levels for severe ulcerative colitis (UC).Patients and Methods: Here, we analyzed blood lipid indicators of 210 patients with UC and 210 healthy individuals who visited the hospital between August 2018 and August 2022. …”
Get full text

Unveiling the effects of post-monsoon agricultural biomass burning on aerosols, clouds, and radiation in Northwest India by Pradeep Khatri, Tadahiro Hayasaka, Prabir K. Patra, Husi Letu, Hiren Jethva, Sachiko Hayashida

“…These findings highlight the potential impacts of agricultural biomass burning activities on the regional climate system and hydrological cycle, emphasizing the need for more detailed studies in the future.…”
Get full text

Assessment of Blood Pressure Control Status Among Hypertensive Patients Attending Rwandan District Hospital NCD Clinics: A Retrospective Follow-Up Study by Evariste Ntaganda, Ziad El-Khatib, Regine Mugeni, Boniface Nsengiyumva, Clarisse Musanabaganwa, James Gafirita, Francois Uwinkindi, Richard Kalisa

“…We assessed blood pressure (BP) control among adult hypertensive patients attending non-communicable disease (NCD) clinics in five Rwandan district hospitals. Methods We extracted data on hypertensive management from five Rwandan district hospitals from June 2016 to August 2021. …”
Get full text

Family Support Moderates the Relationship Between Pregnancy Stress, Depressive Symptoms, and Insomnia by Liu S, Huang M, Zhang F, Tao J, Wen D, Deng W, Lin Y, Zhang P, Li M

“…This study seeks to examine the connections between pregnancy stress, depressive symptoms, family support, and insomnia symptoms.Methods: Convenience sampling was employed to recruit 1049 valid participants. …”
Get full text