Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…This study describes persistence and dose titration among CD patients with 3 years of follow-up. **Methods:** This retrospective observational study was conducted using the STATinMED RWD Insights all-payer medical and pharmacy data. …”
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Differences in catheter-related complications to insertion site selection for long peripheral intravenous catheters in antimicrobial therapy: a randomized controlled trial by Linfang Zhao, Xianghong Jin, Xiangyun Li, Chang Liu, Jie Wang, Xiuzhu Cao, Xufen Zeng, Yiyu Zhuang

“…However, there is no consensus regarding the impact of insertion site selection on the complications associated with long PIVCs. Methods This randomized controlled trial included 90 participants randomly assigned to either the control or experimental group, with 45 patients in each group. …”
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The Effects of Soft Tissue Flossing on Hamstring Range of Motion and Lower Extremity Power by Zachary Maust, Debbie Bradney, Sean M Collins, Caroline Wesley, Thomas G Bowman

“… # Participants Twenty-one recreationally active individuals (8 male, 13 female; age = 22.62±2.99 years; height = 171.52±9.08 cm; mass = 73.57±11.37 kg). # Methods Three counterbalanced interventions were studied during body weight squats, lunges, and hamstring curls (without resistance): floss, sham, and control. …”
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Factors accounting for limited sexual reproduction in a long-lived unisexual plant species by Irene Bisang, Flavien Collart, Flavien Collart, Alain Vanderpoorten, Lars Hedenäs

“…In particular, we test the hypotheses that (i) sex-expressing males and females exhibit different ecological niches and (ii) environmental variation drives sex expression, sporophyte formation, and hence, dispersal capacities.MethodsWe scored 1,080 specimens of the unisexual moss Abietinella abietina across Sweden as non-sex expressing, expressing female or male, or sporophytic. …”
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Effect of nutrition education on hemoglobin level of pregnant women in Southeast Ethiopia: a cluster randomized controlled trial by Girma Beressa, Susan J. Whiting, Tefera Belachew

“…This study aimed to assess the effect of nutrition education on the Hgb levels of pregnant women in urban settings in the Bale Zone, Southeast Ethiopia. Methods A community-based two-arm parallel cluster randomized controlled trial was carried out among 447 randomly selected pregnant women attending antenatal care (224 intervention and 223 control groups) at health facilities from February to December 2021. …”
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Experience of Two-Stage Treatment of Rectal Fistulas Using Low-Thrombin Fibrin Glue “Kriofit” by S. А. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, V. Yu. Korolik, I. S. Bogormistrov, A. N. Ryndin

“…Аim: to improve the results of treatment of patients with rectal fistula.Materials and methods. Twenty-eight patients with rectal fistulas were included in the study — 20 (71,4 %) men and 8 (28,6 %) women, average age — 40 (24–68) years. …”
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The effect of educational intervention based on the mobile application on women’s knowledge, attitude, and practice on microplastics and health: study protocol for a randomized con... by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…In parallel, a randomized controlled trial (RCT) aims to evaluate the effect of interventional education via a mobile phone application on improving women’s knowledge, attitude, and practice regarding the health effects of MPs. Methods This randomized controlled trial includes three phases. …”
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Social Acceptance of Smart Glasses in Health Care: Model Evaluation Study of Anticipated Adoption and Social Interaction by Niek Zuidhof, Oscar Peters, Peter-Paul Verbeek, Somaya Ben Allouch

“…ObjectiveAssuming that smart glasses mediate contact between the health care provider and patient, the objectives of this research are two-fold: (1) to develop an instrument that combines the adoption and mediation perspectives, and (2) to gain insights into how the intention to use is influenced through aspects of adoption and social interaction. MethodsA questionnaire was administered to a target audience of health care professionals (N=450), with recruitment via MTurk. …”
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Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…This study employed a mixed-methods approach to pilot-test a one-day educational seminar about social, medical, and theological aspects of FP. …”
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Prevalence of prolonged transitional neonatal hypoglycemia and associated factors in Ethiopia: A systematic review and meta-analysis. by Solomon Demis Kebede, Amare Kassaw, Tigabu Munye Aytenew, Kindu Agmas, Demewoz Kefale

“…Identifying its prevalence and associated risk factors is critical to inform clinical practices and improve neonatal outcomes.<h4>Methods</h4>A weighted inverse-variance random-effects model was employed for the analysis. …”
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A clinical study on the efficacy and safety of poly-herbal formulation in managing functional dyspepsia by Debasish Hota, Anand Srinivasan, Manas Kumar Panigrahi, Snigdha Suman Dalua, Poorva Tiwari, Ramachandran Valavan

“…This clinical study aimed to evaluate the efficacy and safety of poly-herbal formulation (PHF), marketed under brand names like Dizester® Herbal, Great Day®, etc. in patients suffering from functional dyspepsia compared to Pantoprazole, a commonly used pharmaceutical treatment. Materials &amp; Methods: The study included 80 patients, with 40 patients in each treatment arm. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…To manage the pandemic effectively, Henan Province launched a surveillance program for SARS-CoV-2 variants, systematically analyzing their clinical characteristics and epidemiological patterns.MethodsThis study collected genomic sequence data from 5,965 COVID-19 cases between January 1, 2023, and March 17, 2024, using the Henan Province SARS-CoV-2 variant surveillance system. …”
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Economic and Humanistic Burden of Moderate and Severe Hemophilia A and B in Spain: Real-World Evidence Insights from the CHESS II Study by Carmen Peral, Alfonso De Lossada Juste, Nadia Lwoff, Nataly Espinoza-Cámac, Miguel Ángel Casado, Tom Burke, Jose Alvir, Sheena Thakkar, Enrico Ferri Grazzi

“…**Objective:** To estimate the economic and humanistic burden of disease in adult patients with non-inhibitor moderate and severe HA and HB in Spain. **Methods:** Spanish data from the CHESS II study (2018-2020) on patients' clinical characteristics, health-related quality of life (HRQoL) and hemophilia-related healthcare resource utilization were analyzed. …”
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Factors determining primary or delayed surgery for unilateral, non-metastatic Wilms tumor: a multicentric Egyptian study by Ahmed Elgendy, Amr Abdelhamid AbouZeid, Mohamed El-Debeiky, Shaimaa Abdelsattar Mohammad, Marwa Romeih, Ahmed Ebeed, Mohamed Abouheba, Mohammed Hamada Takrouney, Mahmoud Mostafa, Ahmed Khairi, Osama El-Naggar, Sameh Shehata

“…Clinical characteristics, management details, and outcomes were reviewed. Timing of nephrectomy was analyzed in relation to tumor characteristics such as size, midline crossing, suspicion of perinephric spread, intravascular extension, and retroperitoneal lymphadenopathy. …”
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Diurnal variation in brain injury after cardiac arrest and cardiopulmonary resuscitation by Fei Peng, Fei Wang, Bowen Gao, Ping Sun

“…BackgroundAlthough the circadian rhythm is known to influence several neurological diseases and response to treatments, its potential impact on brain injury following cardiac arrest and cardiopulmonary resuscitation (CA/CPR) remains unclear.MethodsWe performed a retrospective observational study on out-of-hospital cardiac arrest (OHCA) cases that presented to the emergency department of our hospital between September 2022 and August 2024. …”
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Influence of High School Socioeconomic Status on Athlete Injuries during the COVID-19 Pandemic: An Ecological Study by Garrett Bullock, Albert Prats-Uribe, Charles Thigpen, Heather Martin, Beverly Loper, Ellen Shanley

“… # Study Design Ecological Study # Methods High schools were matched between the 2019-2020 and 2020-2021 school years. …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves&rsquo; Disease and Graves&rsquo; Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…We aimed to identify the causal proteins and potential targets for Graves’ disease (GD) and Graves’ ophthalmopathy (GO) via systematic genetic analyses.Methods: Genome-wide association studies (GWASs) on the UK Biobank- Pharma Proteomics Project (UKB-PPP) collected 2923 Olink proteins from 54,219 participants. …”
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Septoplasty: defining a desirable clinical outcome according to baseline symptom scores by Rolf Haye, Rolf Haye, Liv Kari Døsen, Magnus TarAngen, Caryl Gay, Are Hugo Pripp, Olga Shiryaeva

“…Our aim was to establish a DCID according to baseline scores, which should help assess individual results.MethodsPatients (n = 934) rated their nasal obstruction using a visual analog scale (VAS) preoperatively and 6 months postoperatively. …”
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Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY stud... by Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki

“…This study aims to compare the efficacy of relugolix with that of dienogest for reducing endometriosis-associated pain, and to evaluate if relugolix, administered prior to dienogest, decreases abnormal uterine bleeding. Methods A multicenter, open-label, active-controlled, non-inferiority randomized study will be conducted at 11 sites in Japan. …”
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Effects of coal mine dust on lung function in rats by LIU Yang, LI Meng, LU Liyuan, WANG Ru, YANG He, ZHANG Huifang

“…Objective: To explore the impacts of coal mine dust on lung function in rats, so as to provide the basis for the early prevention and treatment of coal worker's pneumoconiosis. Methods: Seventy-two SPF-grade 8-week-old male Sprague-Dawley rats were randomly divided into the coal dust group, the coal-silica dust group, the silica dust group and the control group. …”
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