Effect of pasak bumi (Eurycoma longifolia Jack), DHA, and seluang fish (Rasbora spp.) on neuroinflammation and neurotransmitter alterations in malnourished rats by Triawanti, Didik Dwi Sanyoto, Meitria Syahadatina Noor, Dimas Ikhsan Airlangga

“…Objective: This study aimed to evaluate the effects of pasak bumi in comparison with seluang fish and DHA on neuroinflammation and neurotransmitter imbalances in malnourished rats. Methods: The study involved dividing malnourished rats into six experimental groups: (1) untreated control, (2) treated with pasak bumi extract, (3) treated with DHA, (4) treated with a combination of DHA and pasak bumi extract, (5) treated with seluang fish, (6) treated with a combination of seluang fish and pasak bumi extract; and a control group of normal rats receiving standard feed and placebo. …”
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The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study by Xiangqian Huang, Xiaoming Zhang, Jiahao Song, Duo Lan, Mengqi Wang, Xunming Ji, Da Zhou, Ran Meng

“…This study aimed to investigate the mechanisms by which GBE improves AIS prognosis, particularly its impact on platelet activity, coagulation function, and the potential risk of bleeding. Methods This real-world study consecutively enrolled 99 patients: 49 with internal jugular venous stenosis (IJVS) treated with GBE; 33 with AIS treated with GBE and low-dose aspirin; and 17 with AIS treated with low-dose aspirin alone. …”
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Diagnostic Accuracy of Next Generation Sequencing Panel using Circulating Tumor DNA in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis by Mariana M. Sebastião, Rodrigo S. Ho, João Paulo V. de Carvalho, Micha Nussbaum

“…The aim of the study was to carry out a systematic review and a meta-analysis in order to determine the accuracy of NGS of ctDNA to detect six oncogenic driver alterations: epidermal growth factor receptor (EGFR); anaplastic lymphoma kinase (ALK); ROS proto-oncogene 1, receptor tyrosine kinase (ROS-1); serine/threonine-protein kinase B-RAF (BRAF); RET proto-oncogene (RET); and MET proto-oncogene, receptor tyrosine kinase (MET) exon 14 in patients with aNSCLC. **Methods:** MEDLINE/PubMed, Cochrane Library, Latin American and Caribbean Health Sciences Literature (LILACS), and Centre for Reviews and Dissemination databases and articles obtained from other sources were searched for relevant studies that evaluate the accuracy (sensitivity and specificity) of NGS using ctDNA in patients with aNSCLC. …”
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Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis by Yang Tian, Ming Jin, Nanwei Ye, Zhenzhen Gao, Yuancong Jiang, Sheng Yan

“…However, the underlying mechanisms of how they can protect organ donation after cardiac death (DCD) livers remain unclear. Methods In this study, an arterialized mouse non-heart-beating (NHB) liver transplantation model was used to investigate the effect of MSCs-Exo on NHB liver transplantation. …”
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Association of functional variants in miRNA genes with the risk of coronary heart disease by Taqweem Ul Haq, Muhammad Riaz Khan, Sajjad Ali, Tariq Aziz, Thamer H. Albekairi, Aftab Ali Shah

“…In this study, we investigated the associations of miRNA genes MIR222, MIR423, MIR4274, and MIR3117 with the pathogenesis of CHD. Methods Genetic inheritance models were applied to explore the association between these miRNA genes and CHD. …”
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Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later by Tore K Kvien, Hilde Berner Hammer, Ida K Haugen, Barbara Slatkowsky-Christensen, Alexander Mathiessen

“…Our aim was to explore whether ultrasound-detected osteophytes (in radiographically and clinically normal finger joints) predicted the development of radiographic and clinical hand OA 5 years later.Methods We included finger joints without radiographic OA (Kellgren-Lawrence grade (KLG)=0; n=301) or no clinical bony enlargements (n=717) at baseline and examined whether ultrasound-detected osteophytes predicted incident radiographic OA (KLG ≥1, osteophytes or joint space narrowing (JSN)) or incident clinical bony enlargement (dependent variables) in the same joints 5 years later. …”
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A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms by Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine

“…**Objective:** A systematic review and indirect treatment comparison of clinical trials was conducted to assess the comparative efficacy of RCI and synthetic ACTH treatments in infantile spasms. **Methods:** A search was conducted in MEDLINE, EMBASE, and Cochrane databases through September 30, 2020. …”
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Application of principles of cognitive psychology in teaching: Perspectives from undergraduate medical and dental students. by Ambreen Surti, Shaur Sarfaraz, Rabiya Ali, Mukhtiar Baig, Rehana Rehman

“…These principles were incorporated to educate undergraduate medical and dental students, and the study aims to assess the perspectives of medical and dental students regarding applying these principles.<h4>Methods</h4>The descriptive cross-sectional study was carried out among 555 Bachelor of Dental Surgery (BDS) and Bachelor of Medicine, Bachelor of Surgery (MBBS) students using a validated questionnaire with purposive sampling. …”
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Artificially intelligent nursing homes: a scoping review of palliative care interventions by Isabel Ronan, Sabin Tabirca, Sabin Tabirca, David Murphy, Nicola Cornally, Mohamad M. Saab, Patrice Crowley

“…The aim of this scoping review is to synthesize research surrounding AI-based palliative care interventions in nursing homes.MethodsA PRISMA-ScR scoping review was carried out using modified guidelines specifically designed for computer science research. …”
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Effect of combining different 10-MDP-containing primers and cement systems on shear bond strength between resin cement and zirconia by Kan Wongkamhaeng, Kopchai Poomparnich, Top Chitkraisorn, Kwanwong Boonpitak, Terawat Tosiriwatanapong

“…This study aimed to investigate the combination of 10-MDP-containing primers between the two commercial systems (Scotchbond Universal Plus Adhesive and Panavia V5) and airborne-particle abrasion on shear bond strength (SBS) between zirconia and resin cement. Methods High translucency zirconia discs were sectioned and sintered according to the manufacturer’s recommendations. …”
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Feasibility and effectiveness of a group therapy combining physical activity, surf therapy and cognitive behavioral therapy to treat adolescents with depressive disorders: a pilot... by Bettina Hearn, Monica Biscaldi, Reinhold Rauh, Christian Fleischhaker

“…The aim of the current study was to investigate the feasibility and effectiveness of a group therapy program that combines physical activity, including surf therapy, with cognitive behavioral therapy for treating depression among adolescents.MethodsThirty-two outpatients (28 female, four male) aged 13–18 years with a mean age of 15.58 years (SD = 1.52) and a primary diagnosis of depression were included. …”
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Cost-Effectiveness and Budget Impact of Emerging Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia by Bilal Chughtai, Sirikan Rojanasarot, Kurt Neeser, Dmitry Gultyaev, Stacey L. Amorosi, Neal D. Shore

“…This study evaluated the cost-effectiveness and budget impact of PUL and WVTT for men with BPH using long-term clinical outcomes. **Methods:** The cost-effectiveness and budget impact models were developed from a US Medicare perspective over a 4-year time horizon. …”
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Study on needle anatomical structure and drought resistance of 15 spruce species by ZHAO Li, BAO Xiulan, WANG Fude, FU Sheng, LIU Lijie, HUO Kaiyu

“…[Objective] The study aims to explore the relationship between the anatomical structure of different spruce needles and their drought resistance, to provide reference for spruce conservation research and screening of excellent germplasm resources. [Methods] 15 spruce species that were introduced and cultivated for more than 25 years in Hohhot arboretum were used as materials. …”
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High mortality rates and long-term complications in children with infectious brainstem encephalitis: A study of sixteen cases. by Yuanyuan Zhou, Yi Zhu, Lingfeng Cao, Yingyan Shi, Jun Shen

“…Fewer studies have been conducted on the incidence, clinical manifestations, pathogens and post-infectious sequelae of pediatric infectious BE.<h4>Methods</h4>Pediatric patients diagnosed with BE in our Medical Center from 01 January 2015 to 31 July 2024 were retrospectively reviewed. …”
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Multicystic renal dysplasia, a histomorphological spectrum: Seven years experience from a tertiary care hospital by Kanika Gupta, Shramana Mandal, Varuna Mallya, Meeta Singh, Nita Khurana, Yogesh K. Sarin

“…These are because of the disturbed connection of the ureteric bud with renal blastema and abnormal division at the stage of metanephros, resulting in an abnormal metanephros differentiation. Materials and Methods: Thirty cases of MCDK were included to study their histomorphology along with their clinical features. …”
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Andrographolide prevents acute hyperammonemia-induced motor dysfunction in rats. Evidences for its mechanism of action by Arghya Mukherjee, Santosh Singh

“…Purpose: Present study aimed to explore the therapeutic potentiality of AGP on rat model of non cirrhotic acute HA. Methods: Rotarod and traction test was performed to access the motor function. …”
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Assessing brain-muscle networks during motor imagery to detect covert command-following by Emilia Fló, Daniel Fraiman, Jacobo Diego Sitt

“…The motivation underlying this study was the development of a diagnostic tool that can be applied in common clinical settings to detect awareness in patients that are unable to convey explicit motor or verbal responses, such as patients that suffer from disorders of consciousness (DoC). Methods We examined the brain and muscle response during movement and imagined movement of simple motor tasks, as well as during resting state. …”
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Anemia during pregnancy and adverse maternal outcomes in Georgia-A birth registry-based cohort study. by Natia Skhvitaridze, Amiran Gamkrelidze, Tinatin Manjavidze, Tormod Brenn, Erik Eik Anda, Charlotta Rylander

“…We assessed the prevalence of anemia during pregnancy across Georgia and the association between anemia in the third trimester of pregnancy and adverse maternal outcomes.<h4>Methods</h4>We used data from the Georgian Birth Registry and included pregnant women who delivered between January 1, 2019, and August 31, 2022 (n = 158,668). …”
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A retrospective study of 5S behaviours of Physical Activity (PA) among suburban Mumbai population with Type 2 Diabetes Mellitus (T2DM) by Kosha Parikh, Shikha Thosani, Ameya Joshi, Apoorva Hajirnis, Chandani Seth

“…Methodology: A Retrospective, questionnaire-based study was conducted in the Endocrinology outpatient department of tertiary care institute in Mumbai suburban district. The demographic details, anthropometric measurements, HbA1C levels, sleep cycle and daily PA schedule including the 5S behaviours were recorded. …”
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Examining Muscle Activity Differences During Single and Dual Vector Elastic Resistance Exercises by Ryan WG Bench, Sydney E Thompson, Alan C Cudlip, Michael WR Holmes

“… # Study Design Repeated measures design. # Methods Sixteen healthy university-aged males completed four common shoulder exercises against elastic resistance (abduction, flexion, internal rotation, external rotation) while using a single or dual elastic vector at a fixed cadence and standardized elastic elongation. …”
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