Therapeutic aspects of hormone replacement therapy in postmenopausal women with metabolic syndrome: cardiologist’s opinion by T. V. Adasheva, V. S. Zadionchenko, O. N. Poryvkina, O. Yu. Demicheva, T. M. Terekhova, M. A. Mironova

“…To study the effects of hormone replacement therapy (HRT) on metabolic profile, insulin resistance (IR), central and peripheral hemodynamics, endothelial function and antioxidant activity in postmenopausal women with metabolic syndrome (MS).Material and methods. …”
Get full text

Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism. by Janet Storm, Sonal Sethia, Gavin J Blackburn, Achuthanunni Chokkathukalam, David G Watson, Rainer Breitling, Graham H Coombs, Sylke Müller

“…Phospoenolpyruvate carboxylase (PEPC) is absent from humans but encoded in the Plasmodium falciparum genome, suggesting that PEPC has a parasite-specific function. To investigate its importance in P. falciparum, we generated a pepc null mutant (D10(Δpepc) ), which was only achievable when malate, a reduction product of oxaloacetate, was added to the growth medium. …”
Get full text

Analysis of physiological and biochemical changes and metabolic shifts during 21-Day fasting hypometabolism by Zhongquan Dai, Hongyu Zhang, Xiukun Sui, Feng Wu, Cheng Zhang, Zhiqi Fan, Hailong Wang, Yaxiu Guo, Chao Yang, Siyu Jiang, Linjie Wang, Bingmu Xin, Yinghui Li

“…Physiological indicators such as body weight, blood pressure, blood glucose, blood ketones, and blood uric acid were evaluated along with resting metabolic rate, routine blood tests, liver function, and heart function indexes employing traditional approaches. …”
Get full text

EVALUATION OF LEPTIN SERUM LEVELS IN PATIENTS WITH METABOLIC SYNDROME AND LEFT VENTRICULAR MYOCARDIAL HYPERTROPHY by O. M. Drapkina, R. N. Shepel, T. A. Deeva

“…To study serum level of leptin in patients with the metabolic syndrome (MS), including in patients with MS in combination with left ventricular hypertrophy (LVH) to determine the diagnostic significance of this marker in MS.Material and methods. …”
Get full text

Functional, Nutraceutical, and Health‐Endorsing Perspectives of Ashwagandha by Muhammad Tayyab Arshad, Sammra Maqsood, Ali Ikram, Muhammed Adem Abdullahi

“…The clinical studies have established the benefits of Ashwagandha for mental health, metabolic health, stress reduction, cognitive function, immunity, and cardiovascular health. …”
Get full text

Assessment of bone and mineral metabolism in women with deficiency of body weight at the planning stage of pregnancy by L. P. Shelestova, R. S. Allahverdiev, V. G. Syusyuka

“…Deficiency of body mass characterized by metabolic disorders and lead to various disorders of homeostasis. …”
Get full text

Features of lipid metabolism in chronic heart failure of different genesis with concomitant overweight and obesity by Р. P. Bidzilya

“…To study the features of lipid metabolism in CHF of different genesis with concomitant overweight and obesity. …”
Get full text

The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes. by Andrea Malandrino, Jérôme Noailly, Damien Lacroix

“…Intervertebral disc metabolic transport is essential to the functional spine and provides the cells with the nutrients necessary to tissue maintenance. …”
Get full text

Rad6 Regulates Conidiation by Affecting the Biotin Metabolism in <i>Beauveria bassiana</i> by Yuhan Guo, Haomin He, Yi Guan, Longbin Zhang

“…Rad6 is a canonical ubiquitin-conjugating enzyme known for its role in regulating chromosome-related cellular processes in yeast and has been proven to have multiple functions in <i>Beauveria bassiana</i>, including insect-pathogenic lifestyle, UV damage repair, and conidiation. …”
Get full text

The Multifaceted Role of Psyllium Husk in Enhancing Metabolic and Athletic Performance: A Comprehensive Review by Wiktor Biesiada, Krzysztof Błaszków, Sara Szydłowska, Jagoda Elias, Marlena Zubiak, Justyna Woźniak, Justyna Weronika Kmieć, Ewa Piekarska

“…Psyllium’s prebiotic properties enhance gut microbiota by increasing beneficial bacteria and SCFAs like butyrate, improving glucose metabolism, gut barrier function, and reducing inflammation. …”
Get full text

Cerebral metabolic rate of oxygen is correlated to treatment effect of electroconvulsive therapy in patients with depression by Christoffer Cramer Lundsgaard, André Beyer Mathiassen, Henrik Bo Wiberg Larsson, Poul Videbech, Krzysztof Gbyl, Mark Bitsch Vestergaard

Get full text

Dual inhibition of hepatic ACLY and ACSS2: A synergistic approach to combat NAFLD through lipogenesis reduction and mitochondrial enhancement by Mengdi Zhang, Jinliang Ji, Yuanyuan Lei, Fujian Qin, Yitong Tao, Ning Li, Jinlei Bian, Zhiyu Li, Maode Lai, Zhixia Qiu

Get full text

Morphology and functional organization of subcutaneous adipose tissue: modern concepts of structural and functional heterogeneity and age-related changes (systematic literature rev... by M. A. Shirshakova, S. E. Shemyakov, A. A. Supil'nikov, Yu. E. Mel'nikova

“…Contemporary understanding of structural and functional heterogeneity of adipose tissue has fundamentally changed our perception of its role in metabolic disease pathogenesis and aging processes. …”
Get full text

Proinflammatory Cytokines Trigger the Onset of Retinal Abnormalities and Metabolic Dysregulation in a Hyperglycemic Mouse Model by Gaganashree Shivashankar, Julie C. Lim, Monica L. Acosta

“…To further understand and validate the metabolic biomarkers of DR, we investigated the effect of intravitreal proinflammatory cytokines on the retinal structure, function, and metabolism in an in vivo hyperglycemic mouse model. …”
Get full text

Effects of Bifidobacterium and rosuvastatin on metabolic-associated fatty liver disease via the gut–liver axis by Xue Ran, Ying-jie Wang, Shi-gang Li, Chi-bing Dai

“…These results suggest that the gastrointestinal motility disorder and abnormal liver function in MAFLD rats may be related to a reduction in Escherichia-Shigella bacteria and an increase in Asticcacaulis bacteria in the gut microbiota and that the improvement in liver function induced by Bifidobacterium plus rosuvastatin may be related to increases in Sphingomonas and Odoribacter bacteria and a decrease in Turicibacter bacteria in the gut microbiota. …”
Get full text

Construction of a metabolic‐immune model for predicting the risk of diabetic nephropathy and study of gut microbiota by Mengting Dai, Jianbo Wu, Zhaoyang Ji, Ping Chen, Chengchen Yang, Jialu Luo, Pengfei Shan, Mingzhi Xu

“…Results Compared to patients with diabetes alone, those with DN have a longer disease duration, characterized by abdominal obesity, hypertension, chronic inflammation, activation of the complement system, and declining renal function, along with a significant reduction in Bifidobacterium and Enterobacterium. …”
Get full text

HOPE and AMPK activation reduce reperfusion injury and metabolic dysfunction in primate steatotic liver grafts by Tao Li, Pengkang Chang, Yimeng Wang, Yihong Song, Pengxiang Qu, Bo Wang, Yi Lyu, Liangshuo Hu

“…Abstract Living liver transplantation has become a significant and evolving aspect of organ transplantation, with a notable proportion of cases involving pediatric patients. Metabolic-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease. …”
Get full text

Maternal nutrient restriction in late pregnancy programs postnatal metabolism and pituitary development in beef heifers. by John M Long, Levi A Trubenbach, Kenneth C Hobbs, Andrew E Poletti, Chelsie B Steinhauser, Jane H Pryor, Charles R Long, Tryon A Wickersham, Jason E Sawyer, Rhonda K Miller, Rodolfo C Cardoso, Michael Carey Satterfield

“…Results demonstrate an impaired ability to clear peripheral glucose in heifers born to restricted dams leading to increased deposition of internal fat. A reduction in the number of somatotrophs may contribute to the adipogenic phenotype of heifers born to restricted dams due to growth hormone's known anabolic roles in growth, lipolysis, and pancreatic islet function.…”
Get full text

Two-year Results of Bronchoscopic Lung Volume Reduction Using One-Way Endobronchial Valves: Real-World Single Center Data by Bivort D, Blondeel A, Geysen H, Vandervelde CM, Coolen J, Ceulemans LJ, Dooms C, Janssens W, Everaerts S

“…Dorian Bivort,1,&ast; Astrid Blondeel,2,3,&ast; Hannelore Geysen,1 Christelle M Vandervelde,3,4 Johan Coolen,5 Laurens J Ceulemans,3,4 Christophe Dooms,1,3 Wim Janssens,1,3 Stephanie Everaerts1,3 1Clinical Department of Pulmonary Diseases, University Hospitals Leuven, Leuven, Belgium; 2Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 3Department of Chronic Diseases and Metabolism, BREATHE, KU Leuven, Leuven, Belgium; 4Clinical Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium; 5Clinical Department of Radiology, University Hospitals Leuven, Leuven, Belgium&ast;These authors contributed equally to this workCorrespondence: Stephanie Everaerts, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium, Email stephanie.everaerts@uzleuven.beBackground: Bronchoscopic lung volume reduction (BLVR) using one-way endobronchial valves (EBV) is a minimally invasive treatment for patients with advanced emphysema and severe hyperinflation. …”
Get full text

The role of dipeptidyl peptidase 4 inhibitors in fat metabolism in patients with type 2 diabetes and obesity by Aleksander Sergeevich Ametov, Dinara Gadgimagomedovna Gusenbekova

“…To evaluate the influence of combined therapy of sitagliptin and metformin on fat metabolism in patients with type 2 diabetes mellitus.Methods. …”
Get full text