Dendrobium officinale polysaccharide attenuates type 2 diabetes in mice model by modulating gut microbiota and alleviating intestinal mucosal barrier damage by Xiaoxia Chen, Chun Chen, Changyang Ma, Wenyi Kang, Junlin Wu, Xiong Fu

“…The results showed that DOP improved glycolipid metabolism and serum inflammation levels, and inhibited intestinal-derived lipopolysaccharide (LPS) translocation, suggesting that inhibiting LPS-mediated intestinal barrier damage may be a key target for DOP to alleviate T2DM. …”
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Exploring the in vitro hypolipidemic benefits of bamboo mushrooms: A study on their impact on lipid droplets and adipocytokine levels through metabolome and lipidome profiling by Sucheewin Krobthong, Yodying Yingchutrakul, Chartchai Chaichana, Pawitrabhorn Samutrtai, Jeeraprapa Siriwaseree, Kiattawee Choowongkomon, Pawin Pongkorpsakol, Arnatchai Maiuthed, Pithi Chanvorachote, Chanat Aonbangkhen

“…These findings highlight Bamboo mushroom's capability as a functional food to combat obesity by influencing lipid metabolism.…”
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Brazil nut consumption within an energy-restricted diet improved cardiometabolic risk markers in women: a quasi-experimental, controlled study (Brazilian Nuts Study) by ALESSANDRA DA SILVA, BRENDA KELLY S. SILVEIRA, BRENDA V.M. DE FREITAS, KARINA WASKOW, HELEN HERMANA M. HERMSDORFF, WALMIR DA SILVA, JOSEFINA BRESSAN

“…Abstract Consuming functional foods alongside the energy-restricted diet can be a great ally in weight loss and improving cardiometabolic risk factors. …”
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Nitrogen‐Doped Multiwalled Carbon Nanotubes Trigger Immune Responses and Inhibit Fat Deposition by Dalin He, Xue Xiao, Geng Hu, Wenqian Zhang, Guanliu Yu, Yan Liu, Yun Lin, Hai Lin, Xianyao Li, Youxiang Diao, Yi Tang, Haifang Li

“…However, it's unclear to their effects on fat metabolism. Here, it is demonstrated that nitrogen‐doped carboxylate‐functionalized MWCNTs (N‐MWCNTs) inhibit fat deposition both in vivo and in vitro. …”
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The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis by Xin Wu, Yongmin Zheng, Jie Ma, Jie Yin, Shuai Chen

“…Glycine (Gly) is the simplest amino acid and functions as an anti-inflammatory immune-nutrient and intestinal microbiota regulator. …”
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Gut Microbiota-Derived Trimethylamine Promotes Inflammation with a Potential Impact on Epigenetic and Mitochondrial Homeostasis in Caco-2 Cells by Laura Bordoni, Irene Petracci, Giulia Feliziani, Gaia de Simone, Chiara Rucci, Rosita Gabbianelli

“…Trimethylamine (TMA), a byproduct of gut microbiota metabolism from dietary precursors, is not only the precursor of trimethylamine-N-oxide (TMAO) but may also affect gut health. …”
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Glutamate dehydrogenase from Pantoea ananatis: A new bacterial enzyme with dual coenzyme specificity. by Maria S Kharchenko, Victoria S Skripnikova, Julia G Rostova, Natalia P Zakataeva

“…Glutamate dehydrogenase (GDH) catalyzes the reversible conversion of α-ketoglutarate (α-KG) to L-glutamate (Glu) and plays an important role in linking nitrogen and carbon metabolism. However, little is known about this enzyme in the biotechnologically important bacterium Pantoea ananatis. …”
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Autism-Like Behaviours and Memory Deficits Result from a Western Diet in Mice by Ekaterina Veniaminova, Raymond Cespuglio, Chi Wai Cheung, Alexei Umriukhin, Nataliia Markova, Elena Shevtsova, Klaus-Peter Lesch, Daniel C. Anthony, Tatyana Strekalova

“…These changes can be associated with abnormalities in social behaviour, hippocampus-dependent cognitive functions, and metabolism. Female C57BL/6J mice were fed with a regular chow or with a WD containing 0.2% of cholesterol and 21% of saturated fat for three weeks. …”
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Stage-Specific Transcriptomic Insights into Seed Germination and Early Development in <i>Camellia oleifera</i> Abel. by Zhen Zhang, Caixia Liu, Ying Zhang, Zhilong He, Longsheng Chen, Chengfeng Xun, Yushen Ma, Xiaokang Yuan, Yanming Xu, Rui Wang

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Magnetically sensitive nanocomposites for targeted antitumor therapy with application of gemcitabine by N. M. Korniichuk, S. P. Turanska, A. L. Petranovska, M. V. Abramov, P. P. Gorbyk, N. Yu. Luk'yanova, N. V. Kusyak, V. F. Chekhun

“…It has been proved that when using MF based on targeted Fe3O4/GEM/HER2 complex, the increased antitumor efficacy is observed compared to traditional use of the drug GEM, with a significant reduction (by four times) of its dose. The high cytotoxic/cytostatic activity of Fe3O4/GEM/HER2 complexes is explained by the fact that endogenous iron metabolism disorders play a significant role in the mechanisms of realization of the apoptotic program under the influence of nanocomposite. …”
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Ovariectomy-induced bone loss through inappropriate inflammatory response: an osteoimmunological perspective on postmenopausal osteoporosis by Lilika Higuchi, Nozomi Ouchi, Yasuyuki Negishi, Munehiro Naruo, Maiko Kusano, Shunji Suzuki, Takahisa Okuda, Rimpei Morita

“…These findings highlight the complex interplay between immune responses and lipid metabolism in PO and propose novel therapeutic strategies aimed at modulating immune function to prevent bone loss. …”
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Strategy for nitrogen fertilizer substitution: Co-composting of agricultural waste to regulate vegetable quality and rhizosphere microorganisms by Xiaoning Liu, Qiang Wang, Yupeng Wang, Shizhou Shen, Yihong Ge, Ke Pan, Xiaobo Guo, Yunhui Lei, Yi Gao

“…Proteobacteria and Ascomycota are important microbial families that affect the growth and quality indicators of pakchoi, respectively. Functional analysis showed that the compost mainly regulated the growth and quality of pakchoi by upregulating the relative abundance of functional genes related to carbohydrate metabolism, lipid metabolism, and exogenous biodegradation and metabolism, as well as by increasing the abundance of symbiotic and saprotrophic fungi while decreasing that of pathotrophic fungi. …”
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Comparative Analysis of Ratoon-Competent and Ratoon-Deficient Sugarcane by Hormonal and Transcriptome Profiling by Liping Zhao, Maoyong Ran, Jing Zhang, Peifang Zhao, Fenggang Zan, Jun Zhao, Wei Qin, Qibin Wu, Jiayong Liu, Xinlong Liu

“…The quantification of 15 endogenous hormones via HPLC revealed marked reductions in zeatin (ZA) and zeatin riboside (ZR) in both cultivars. …”
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Genome‑wide identification of the cotton FAR gene family reveals GhFAR3 as a positive regulator of Verticillium dahliae resistance by Wenhan Cheng, Siqi Gao, Zhaojie He, Nurimanguli Aini, Zengqiang Zhao, Xianpeng Xiong, Ning Wang, Rui Chen, Keyun Feng

“…Among them, GhFAR3 showed strong induction upon pathogen challenge. Functional validation using virus-induced gene silencing (VIGS) demonstrated that silencing GhFAR3 compromised resistance to V. dahliae, correlating with a marked reduction in suberin deposition in root tissues. …”
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Case Report: Concurrent de novo pathogenic variants in the LMNA gene as a cause of sporadic partial lipodystrophy by José L. Santos, José L. Santos, José Patricio Miranda, José Patricio Miranda, Carlos F. Lagos, Carlos F. Lagos, Víctor A. Cortés

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The peculiarities of changes in myocardial electrical activity and heart rate variability in patients with coronary artery disease depending on the stage of concomitant iron defici... by M. O. Konovalova, N.S. Mikhailovska

“…There were no statistically significant correlations between indicators of iron metabolism and HRV in patients with CAD and functional ID. …”
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Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis by Siqi Ye, Siqi Ye, Jingwen Wang, Jingwen Wang, Feng Luo, Feng Luo, Jinjing Jia, Jinjing Jia, Xiumei Mo, Xiumei Mo, Dacan Chen, Dacan Chen

“…These findings provide valuable insights into the mechanisms of AD occurrence and progression, microbial community dynamics, metabolic regulation, and functional food innovation.…”
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Mixed Sweeteners Supplemented with Chromium Picolinate (CrPic) Improved Some Diabetes-Related Markers and Complications in a Type 2 Diabetic Rat Model by Ekomobong Inyang, Ifeoma Irene Ijeh, Sunday Oyedemi

“…The treatment also modulated specific renal function parameters, and moderately reversed the necrotic architectures of the liver and pancreatic β cells. …”
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Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension by Francesco Paolo Lo Muzio, Alessia Caputo, Rosario Statello, Mirko Hu, Roberta Maestri, Giovanna Pelà, Aderville Cabassi, Margherita Burattini, Giacomo Rozzi, Silvia Berrettoni, Barbara Montanini, Stefano Rossi, Lorenzo Fassina, Giovanni Battista Luciani, Gianluigi Condorelli, Michele Miragoli

“…Methods In this study, we investigate the late-stage effects of PAH on both electrical and mechanical functions, as well as their coupling, in each ventricle using the monocrotaline-treated rat model. …”
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Plastome and transcriptome analysis reveals a degenerated photosynthesis-related pathway in the mycoheterotrophic vanilloid orchid Cyrtosia lindleyana by Shiou Yih Lee, Peishan Zou, Zhihui Chen, Kenji Suetsugu, Wenbo Liao

“…Results The plastome, despite its reduction to 89,414 base pairs, maintained its quadripartite structure. …”
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