Metabolic effects of bezafibrate in mitochondrial disease by Hannah Steele, Aurora Gomez‐Duran, Angela Pyle, Sila Hopton, Jane Newman, Renae J Stefanetti, Sarah J Charman, Jehill D Parikh, Langping He, Carlo Viscomi, Djordje G Jakovljevic, Kieren G Hollingsworth, Alan J Robinson, Robert W Taylor, Leonardo Bottolo, Rita Horvath, Patrick F Chinnery

“…There were no clinically significant adverse events, and liver function was not affected. We detected a reduction in the number of complex IV‐immunodeficient muscle fibres and improved cardiac function. …”
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METABOLIC THERAPY IN PATIENTS WITH ISCHEMIC STROKE by L. B. Zavaliy, S. S. Petrikov, A. V. Schegolev

“…The article shows the world experience of metabolic therapy use in the treatment of ischemic stroke. …”
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Dysregulated gastric microbial communities and functional shifts in chronic atrophic versus non-atrophic gastritis: a Helicobacter pylori-Negative observational study by Hong Yao, Tingting Liu, Yiming Chen, Ling She, Tingfeng Wu, Dongsong Liu, Yuhong Deng, Yubin Han, Kai Chen, Jianmin Deng, Jue Zhang, Jinfeng Chen, Fengbin Liu

“…In contrast, the CNAG group showed enrichment in amino acid metabolism, translation, replication/repair, and terpenoid/polyketide metabolism. …”
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Assessment of lipid metabolism in thyroid dysfunction by V. G. Kadzharyan, A. I. Melnik, P. P. Bidzilya, S. A. Solovyuk

“…To define features of lipid metabolism, depending on the functional state of the thyroid gland. 3. …”
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Acupuncture-assisted lifestyle intervention improve the metabolic status and spontaneous brain activity of type 2 diabetes Mellitus patients: a randomized, clinical trial by Zhitian Zhang, Kaixuan Bao, Jiaojiao Liu, Chunfei Jiang, Chunyan Ji, Jiawei Han, Guo Zhou, Xiaoyu Liu, Tiemin Liu, Jian Gao, Xiangyu Wang, Hongmei Yan

“…Abstract Background Aggressive weight management in patients with type 2 diabetes mellitus has demonstrated numerous metabolic advantages, however, existing therapies for weight control have not reached satisfactory results. …”
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Correlation analysis between clinical effective emotional treatment and plasma N-methyl-D-aspartate receptor function-related indexes by Zuxing Feng, Yanli Li, Ying Cai, Fan Yang, Fan Yang, Xiangfeng Zhou, Maoyang Feng, Li Wu

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Reduction of neuronal activity mediated by blood-vessel regression in the adult brain by Xiaofei Gao, Xing-jun Chen, Meng Ye, Jun-Liszt Li, Nannan Lu, Di Yao, Bo Ci, Fei Chen, Lijun Zheng, Yating Yi, Shiwen Zhang, Zhanying Bi, Xinwei Gao, Yuanlei Yue, Tingbo Li, Jiafu Lin, Ying-Chao Shi, Kaibin Shi, Nicholas E. Propson, Yubin Huang, Katherine Poinsatte, Zhaohuan Zhang, Dale B. Bosco, Shi-bing Yang, Ralf H. Adams, Volkhard Lindner, Fen Huang, Long-Jun Wu, Hui Zheng, Simon Hippenmeyer, Ann M. Stowe, Bo Peng, Marta Margeta, Qingchun Guo, Xiaoqun Wang, Qiang Liu, Jakob Körbelin, Martin Trepel, Hui Lu, Guoen Cai, Bo O. Zhou, Bo Shen, Ying-mei Lu, Wenzhi Sun, Jie-Min Jia, Feng Han, Hu Zhao, Robert M. Bachoo, Woo-ping Ge

“…We further reveal that blood vessel regression cause a reduction of neuronal activity due to a dysfunction in mitochondrial metabolism and glutamate production. …”
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Delta‐9 desaturase reduction in gastrointestinal cells induced to senescence by doxorubicin by Valentina De Nunzio, Emanuela Aloisio Caruso, Matteo Centonze, Giuliano Pinto, Miriam Cofano, Ilenia Saponara, Maria Notarnicola

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METABOLIC EFFECTS OF VARIOUS ANTIHYPERTENSIVE DRUG COMBINATIONS by E. E. Alimova, M. V. Leonova, Yu. B. Belousov

“…In all participants, the parameters of lipid, carbohydrate, and purine metabolism were assessed. The effects of antihypertensive combinations on the risk of metabolic disturbances were studied using the factor regression analysis of quantitative and qualitative parameters (factors) as weighted ordered functions. …”
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Weight reduction as a non-pharmacological treatment method for type 2 diabetes by Mikołaj Borek

“…Weight reduction is a crucial com-ponent of the non-pharmacological treatment for this condition, improving insulin sensitivity, β-cell function, and lipid metabolism. …”
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Milk lacking α-casein leads to permanent reduction in body size in mice. by Andreas F Kolb, Reinhard C Huber, Simon G Lillico, Ailsa Carlisle, Claire J Robinson, Claire Neil, Linda Petrie, Dorte B Sorensen, I Anna S Olsson, C Bruce A Whitelaw

“…The major physiological function of milk is the transport of amino acids, carbohydrates, lipids and minerals to mammalian offspring. …”
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Age and estrogen-associated reductions in hypoxic ventilatory response and chemosensitivity in female rats by Jessica M. L. Grittner, Rebecca Barok, Edgar Juarez Lopez, Misha Shah, Brendan J. Dougherty

“…The current study aimed to interrogate whether the OVX model of hormone reduction impacted specific aspects of respiratory function [chemosensitivity and the hypoxic ventilatory response (HVR)] in a manner consistent with natural age-related declines in hormones. …”
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Arthroscopic versus open fixation for medial malleolus fractures improves trauma response and bone healing by Xihong Xie, Danting Ji, Feiqiang Chen, Zejin Lin, Kai Deng, Jinqi Song, Jing Wang

“…Arthroscopy-assisted reduction and percutaneous internal fixation for isolated medial malleolus fracture can minimize intraoperative bleeding, reduce trauma, expedite fracture healing, enhance ankle functional recovery, making it a valuable technique for clinical application.…”
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Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions by S. V. Petlenko, E. G. Golovacheva, O. I. Afanasieva

“…Following the immunotropic therapies, the subjects showed an increase in relative content of CD3+, CD4+, and CD8+ subpopulations, normalization of functional oxygen-dependent metabolism of polymorphonuclear neutrophil granulocyte system in the NBT test, as well as harmonization of the content of serum immunoglobulin contents. …”
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Efficacy of Adding Sitagliptin to Ongoing Metformin on Metabolic Profile, Triglyceride-Glucose Index, Vitamin D3, and Liver Tests in Patients Type 2 Diabetes Mellitus and Nonalcoho... by Habib Yaribeygi, PhD, Majid Ramezani, MD, Niki Katsiki, PhD, MD, Majid Mirmohammadkhani, PhD, Narges Sadat Tabaei, Msc

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Efficacy of Actovegin in the treatment of the central and the peripheral nervous system by L. M. Boriskina

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The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease by Jiayuan Murphy, Tran Ngoc Van Le, Julia Fedorova, Yi Yang, Meredith Krause-Hauch, Kayla Davitt, Linda Ines Zoungrana, Mohammad Kasim Fatmi, Edward J. Lesnefsky, Edward J. Lesnefsky, Ji Li, Di Ren

“…This study aims to characterize cellular defects resulting in decreased cardiac function in AD-model. 5XFAD mice, a strain expressing five mutations in human APP and PS1 that shows robust Aβ production with visible plaques at 2 months and were used in this study as a model of AD. 5XFAD mice and wild-type (WT) counterparts were subjected to echocardiography at 2-, 4-, and 6-month, and 5XFAD had a significant reduction in cardiac fractional shortening and ejection fraction compared to WT. …”
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Adipokines in metabolic processes regulating during obesity treatment by Larisa Sergeevna Litvinova, Maria Alexandrovna Vasilenko, Pavel Anatol'evich Zatolokin, Natalya Nikolaevna Aksenova, Nikolay Sergeevich Fattakhov, Igor Zinov'evich Vaysbeyn, Natalya Ivanovna Mironyuk, Elena Vital'evna Kirienkova

“…Bariatric surgery serves as a model for the assessment of the relationship between body mass index (BMI) reduction and changes in adipokine production and for exploring the endocrine function of the pancreas in patients who do not have the proximal part of the small intestine. …”
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Metabolic Reprogramming in Gut Microbiota Exposed to Polystyrene Microplastics by Jinhua Chi, Jeffrey S. Patterson, Yan Jin, Kyle Joohyung Kim, Nicole Lalime, Daniella Hawley, Freeman Lewis, Lingjun Li, Xuan Wang, Matthew J. Campen, Julia Yue Cui, Haiwei Gu

“…In this pilot study, we hypothesize that MPs exposure will negatively affect gut microbiota composition and function, in which metabolic reprogramming plays an important role. …”
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KNEE OSTEOARTHRITIS AND METABOLIC SYNDROME: NEW APPROACHES TO THERAPY by L. I. Alekseeva, E. A. Taskina, N. G. Kashevarova, E. P. Sharapova, S. G. Anikin, E. A. Strebkova, T. А. Korotkova, T. A. Raskina, E. V. Zonova, E. N. Otteva

“…During therapy, there is a rapid and considerable reduction in pain and stiffness and an improvement in the functional state. …”
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