Using 3D and 4D digital human modeling in extended reality-based rehabilitation: a systematic review by Mengdi Lu, Wim Saeys, Wim Saeys, Maria Maryam, Inva Gjeleshi, Hoda Nazarahari, Steven Truijen, Sofia Scataglini

“…The studies reveal positive impacts on functional (e.g., upper limb function, gait, balance, quality of life), physical (e.g., pain reduction, spasticity, joint range), psychological (e.g., depression, emotional regulation, body image), and general health outcomes (e.g., body composition, metabolic health).ConclusionDespite variability in study parameters, limited evidence suggests that 3D DHM in XR-based rehabilitation may enhance physical and psychological recovery across various pathologies. …”
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Analysis of options for using oxygen-helium mixture in complex therapy and rehabilitation of patients with various diseases of the respiratory organs (review of literature) by Yu. A. Khatuntseva, V. M. Manuylov, A. N. Shcherbyuk, Ya. E. Nemstsveridze, A. A. Andrushchenko, G. I. Kurnakin

“…The safety of use, absence of toxic effects and metabolic changes make CGS the method of choice for patients with limited sensitivity to standard pharmacotherapy. …”
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THE EFFECTIVENESS OF MEDICAL REHABILITATION IN CORONARY HEART DISEASE AS A PART OF THE SPA RESORT TREATMENT by A. S. Ivashchenko, V. V. Iezhov, N. A. Severin, N. A. Prokopenko

“…Reliable positive trends were set for a number of domains: the sensation of pain and dizziness (b280 and b2401), blood pressure (b420), tolerance to physical exercises (b455), general metabolic functions (b540) and the sensations associated with the functioning of the cardiovascular and respiratory systems (b4601).Conclusions. …”
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Organ-on-a-Chip Models—New Possibilities in Experimental Science and Disease Modeling by Bartłomiej Wysoczański, Marcin Świątek, Anna Wójcik-Gładysz

“…By consolidating multicellular structures, tissue–tissue interfaces, and physicochemical microenvironments, these microchips can replicate key organ functions. They also enable the high-resolution, real-time imaging and analysis of the biochemical, genetic, and metabolic activities of living cells in the functional tissue and organ contexts. …”
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CLK2 blockade modulates alternative splicing compromising MYC‐driven breast tumors by Fernando Salvador, Roger R Gomis

“…Abstract MYC oncogene overexpression/amplification is common in multiple human cancers, in which it regulates proliferation, apoptosis and cell metabolism, among other processes, and its expression associates with poor prognosis. …”
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PROGRESSING CHRONIC KIDNEY DISEASE AND THE 12-MONTH DYNAMICS OF CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH ARTERIAL HYPERTENSION AND TYPE 2 DIABETES MELLITUS by A. V. Markova, Yu. G. Schwartz

“…The direction of renal function parameter changes was determined by the baseline CKD stage. …”
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Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs. by Francesca Gabanella, Matthew E R Butchbach, Luciano Saieva, Claudia Carissimi, Arthur H M Burghes, Livio Pellizzoni

“…SMN together with Gemins2-8 and unrip proteins form a macromolecular complex that functions in the assembly of small nuclear ribonucleoproteins (snRNPs) of both the major and the minor splicing pathways. …”
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Losartan in postmenopausal women with essential arterial hypertension by O. N. Tkacheva, A. V. Barabashkina, I. M. Novikova, N. V. Sharashkina

“…In postmenopausal women with AH, adding losartan to the AHT scheme demonstrated good antihypertensive effectiveness, insulin sensitivity normalization, endothelial function and lipid profile improvement. Among women receiving AHT and HRT, antihypertensive effect, as well as beneficial effects on endothelial function and lipid profile, was greater than in women receiving AHT only.…”
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The antifungal peptide AnAFP from Aspergillus niger promotes nutrient mobilization through autophagic recycling during asexual development by Stephan Starke, Laura Velleman, Birgit Dobbert, Luis Seibert, Jordi Witte, Sascha Jung, Vera Meyer

“…Comparative transcriptome analyses of glucose-starving mycelium demonstrated that increased anafp expression strongly impacts expression of genes important for cell wall integrity and remodeling, as well as genes with a predicted function in metabolism and transport of carbohydrates, proteins, and lipids. …”
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Estimating energy expenditure from heart rate in older adults: a case for calibration. by Jennifer A Schrack, Vadim Zipunnikov, Jeff Goldsmith, Karen Bandeen-Roche, Ciprian M Crainiceanu, Luigi Ferrucci

“…<h4>Background</h4>Accurate measurement of free-living energy expenditure is vital to understanding changes in energy metabolism with aging. The efficacy of heart rate as a surrogate for energy expenditure is rooted in the assumption of a linear function between heart rate and energy expenditure, but its validity and reliability in older adults remains unclear.…”
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Combined Physiology and Transcriptome Analyses Provide Insights into Malformed Fruit of <i>Cocos nucifera</i> L. by Lilan Lu, Zhiguo Dong, Yuan Zhang, Siting Chen, Qingxin Wu

“…Conversely, a coordinated upregulation of phytohormones was observed, where indole acetic acid (IAA), abscisic acid (ABA), cytokinin (CK), gibberellic acid (GA), brassinosteroid (BR), jasmonic acid (JA), and salicylic acid (SA) levels increased by 31.82–92.97%, while ethylene (ETH) exhibited a paradoxical 30.09% reduction. Transcriptomic dissection revealed 6370 functionally annotated differentially expressed genes (DEGs), comprising 4235 upregulated and 2135 downregulated transcripts. …”
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C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2. by Bedoor Qabazard, Samanza Ahmed, Ling Li, Volker M Arlt, Philip K Moore, Stephen R Stürzenbaum

“…Exogenous hydrogen sulfide (H2S) administration and endogenous H2S metabolism were explored in the nematode C. elegans. …”
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Pathogenetic treatment with strontium ranelate in women with postmenopausal osteoporosis by Olga Borisovna Yershova

“…The system of osteoprotegerin (OPG), receptor activator of nuclear factor-κ B and its ligand has been confirmed to play a central role in the regulation of bone metabolism. At the same time, there is strong evidence that OPG performs a key function in bone metabolism regulation, by suppressing the differentiation of osteoclasts (OC) and reducing their activity. …”
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Serum Antithyroglobulin Antibody Levels Are Associated with Diabetic Retinopathy among Euthyroid Type 2 Diabetes Patients: A Hospital-Based, Retrospective Study by Xiaotong Gao, Xichang Wang, Yifan Zhong, Lei Liu, Weiping Teng, Zhongyan Shan

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The association between cruciferous vegetable consumption and Perfluorooctanesulfonic acid bioaccumulation: A cross-sectional analysis of the US population and cross-country random... by Xiaobing Zhai, Junjun Ji, Jing Wang, Jinji Bai, Xuechen Zhao, Wenjie Zhang, Ruyan Lv, Xuan Deng, Qixiu Li, Weiyu Meng, Qianqian Zhang, Jinyuan Zhao, Jiajing Cui, Li Yu, Chi Kin Lam, Chan Zhang, Henry H.Y. Tong, Yuefei Wang, Xicheng Song, Kaiqiang Wang, Junfeng Li, Kefeng Li

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Mechanism of Diabetes Remission or Improvement in Glucose Control Following Roux-en-Y Gastric Bypass Versus Sleeve Gastrectomy: A Systematic Review and Meta-Analysis by Rebekah Wilmington, Arash Ardavani, Nebras Hasan, Yousef Alhindi, Imran Ramzan, Oluwaseun Anyiam, Iskandar Idris

“…Conclusions: Diabetes remission following RYGB and SG was primarily driven by improvement in beta-cell function, with improvement in insulin resistance markers also observed for RYGB, driven by reductions in fat mass. …”
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Comparative transcriptomic and genomic analysis of tumor cells in the marginal and center regions of tumor nests in human hepatocellular carcinoma by Ziyi Li, Ziyi Li, Yikai Hu, Yikai Hu, Zhuotian He, Heyi Xu, Hongyang Wang, Hongyang Wang, Hongyang Wang, Yufei He

“…This center-margin functional division may inform rational design of therapeutics that simultaneously modulate metabolism and immune responses.…”
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Plant growth-promoting endophytic consortium improved artemisinin biosynthesis via modulating antioxidants, gene expression, and transcriptional profile in Artemisia annua (L.) und... by Arpita Tripathi, Praveen Pandey, Shakti Nath Tripathi, Alok Kalra

“…In summary, our study reflects the potential of the endophytic consortium for strengthening one endophyte's functional vulnerability with another to gain maximum artemisinin yield and plant tolerance against various stresses via regulating essential metabolic pathway genes.…”
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Role of diet, physical activity and new drugs in the primary management of cancer cachexia in gastrointestinal tumors – a comprehensive review by Ester Oneda, Alessandra Manno, Silvia Noventa, Michela Libertini, Sara Cherri, Alberto Zaniboni

“…Targeted dietary strategies, such as a high-protein diet enriched with omega-3 and branched-chain amino acids (BCAAs), have proven effective in counteracting muscle loss and modulating inflammatory metabolism. Physical activity, particularly resistance training, contributes to preserving lean mass and improving physical function. …”
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Enzymatic Regulation of the Gut Microbiota: Mechanisms and Implications for Host Health by Zipeng Jiang, Liang Mei, Yuqi Li, Yuguang Guo, Bo Yang, Zhiyi Huang, Yangyuan Li

“…Enzymes serve both traditional nutritional functions, such as the breakdown of complex substrates into absorbable small molecules, and non-nutritional roles, which encompass antibacterial function, immunomodulation, intestinal health maintenance, and stress reduction, among others. …”
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