The Role of PPARs in Cancer by Keisuke Tachibana, Daisuke Yamasaki, Kenji Ishimoto, Takefumi Doi

“…Here, we review the function of PPARs in tumor growth.…”
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Physiological Effects of Smoke Exposure on Deciduous and Conifer Tree Species by W. John Calder, Greg Lifferth, Max A. Moritz, Samuel B. St. Clair

“…Impairment of photosynthesis in response to smoke was a function of reductions in stomatal conductance and biochemical limitations. …”
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A Drosophila model of high sugar diet-induced cardiomyopathy. by Jianbo Na, Laura Palanker Musselman, Jay Pendse, Thomas J Baranski, Rolf Bodmer, Karen Ocorr, Ross Cagan

“…We provide evidence of a role for hexosamine flux, a metabolic pathway accessed by glucose. Increased hexosamine flux led to heart function defects and structural damage; conversely, cardiac-specific reduction of pathway activity prevented sugar-induced heart dysfunction. …”
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Sexually dimorphic impact of prenatal hyperandrogenism on offspring growth trajectory in sheep by Eylem Topaktas, Joseph Ciarelli, Stephanie Domke, Brooke Pallas, Adel Ghnenis, Mansi Agarwal, Charles Goss, Kevin Cho, Leah P. Shriver, Gary J. Patti, Vasantha Padmanabhan, Arpita Kalla Vyas

“…Altered sex-specific postnatal metabolic milieu and growth trajectory, notable for catch-up growth in T-Female, could have implications for sex-specific impact on the cardiometabolic function in the lambs.…”
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Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells by Bruna Cristina Falavinha, María Julia Barisón, Carmen Lúcia Kuniyoshi Rebelatto, Bruna Hilzendeger Marcon, Alessandra de Melo Aguiar, Evelin Brandão da Silva, Marco Augusto Stimamiglio, Patrícia Shigunov

“…Although the receptor has been associated with metabolic diseases, few studies have examined its function in stem cells. …”
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Review article: key aspects of mammal microbiome development by E. V. Semenova, O. A. Manzhurina, Yu. S. Parkhomenko

“…The microbiome is known to have an impact on the immune system development, metabolic processes and even on the ethology, so an atypical microbial population can cause immune and metabolic disorders. …”
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Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application by Xiaoting Li, Shunping Yu, Shiqing Zhang, Yubin Xiong, Fangfang Zhou, Li Tang

“…By integrating microbiology and metabonomics, we aimed to elucidate the effects of long-term different fertilizer measures on the rhizosphere soil microbial community and metabolic function. Compared with CF, the relative abundance of Phytophthora nicotianae in rhizosphere soil and corresponding disease significantly decreased with BOF. …”
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Differential benefits of 12-week morning vs. evening aerobic exercise on sleep and cardiometabolic health: a randomized controlled trial by Bingyi Shen, Huiwen Zheng, Haibin Liu, Lihong Chen, Guangrui Yang

“…Evening exercise (6–8 p.m.) is more effective for enhancing vascular function. Trial registration: Chinese Clinical Trial Registry, ChiCTR2400094208, 18/12/2024.…”
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A Mixed Method Study on Kidney Transplant Recipients’ Quality of Life by Bheru Singh Chundawat, Dharmesh Chaturvedi, Vaneshvar Suthar, Kapil Gupta, Kaushlendra Singh Yadav, Shweta Pattnaik

“…It occurs with a gradual reduction in the function of the kidneys over time. …”
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Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance. by Ashley Houlden, Kelly S Hayes, Allison J Bancroft, John J Worthington, Ping Wang, Richard K Grencis, Ian S Roberts

“…The significant reduction in weight gain by infected mice probably reflects these metabolic changes and the incomplete digestion of dietary polysaccharides. …”
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Clinical rationale for the use of various teraflex formulations in osteoarthrosis by Natalia Vladimirovna Chichasova

“…It is noted that the use of agents that are potentially able to modify cartilage metabolic processes attracts attention above all due to the possibility of achieving a permanent reduction in the magnitude of pain and inflammation in OA and their safety in its treatment. …”
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Some physiological and biochemical changes in women with hyperthyroidism by Sarab D. Kh.

“…There is interaction among hypothalamus gland, pituitary gland and thyroid gland system in regulation of metabolic and function of body, this achieved by balance between hormonal stimulation with drawl of other hormone by feed back mechanism, any changes in this hormonal balance lead to thyroid gland disorders , the present study was carried out to evaluate the effect of hyperthyroidism on some physiological blood properties is Hb, WBC, RBC, blood pressure, determination the concentration of thyroid hormones (T3, T4, TSH) for patients (N=50) which compared with control group (N=50). …”
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Application of Meldonium for the Treatment of Patients with Diabetic Nephropathy by Topchii І.

“…The additional use of Meldonium promotes the further improvement of the morphological structure and contractile function of the myocardium through its complex effects on metabolic processes and the exchange of NO. …”
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The cAMP responsive element modulator (CREM) transcription factor influences susceptibility to undernutrition and infection by Audrey C. Brown, Md. Jashim Uddin, Rebecca M. Munday, Farha Naz, G. Brett Moreau, Girija Ramakrishnan, Stephen S. Rich, Rashidul Haque, Genevieve L. Wojcik, Priya Duggal, Chelsea Marie, William A. Petri

“…In mice, global conditional deletion of Crem resulted in reduced body weight, downregulation of genes related to innate immune function, and upregulation of metabolic gene expression in the intestine. …”
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Impact of a fructose-free diet on anthropometric measurements: an interventional study by Ali Hussein Talib Alaqdawi, Saja Ali Ahmed, Monaf Faik Al-Samarraee, Muthana Abdulrazzaq Jabbar

“…Secondary outcomes assessed anthropometric parameters, lipid profiles, and liver function markers. Results: Both groups achieved significant waist circumference reductions without between-group differences (FFD: -12.4±8.2cm vs Control: -13.1±7.8cm, p>0.05). …”
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Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome by Silvia Giugliano, Andrea Gatti, Martina Rusin, Tilo Schorn, Silvia Pimazzoni, Michela Calanni-Pileri, Valentina Fraccascia, Sara Carloni, Maria Rescigno

“…Furthermore, gut dysbiosis significantly perturbs placental carbohydrate metabolism, which impairs NK cell IFN-γ secretion. Notably, glucose supplementation restores placental NK cell function and reduces fetal resorption, suggesting that the observed impairment is reversible and dependent on a lower glycolytic rate. …”
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Caloric Restriction and Sirtuins as New Players to Reshape Male Fertility by Diana C. A. André, Pedro F. Oliveira, Marco G. Alves, Ana D. Martins

“…Concerning testicular function and male fertility, sirtuins can modulate certain metabolic processes through their interaction with the hypothalamic–pituitary–gonadal axis and mitochondrial dynamics, among many others, which remain largely unexplored. …”
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Wearable Adaptive Resistance Training Improves Ankle Strength, Walking Efficiency and Mobility in Cerebral Palsy: A Pilot Clinical Trial by Benjamin C. Conner, Nushka M. Remec, Elizabeth K. Orum, Emily M. Frank, Zachary F. Lerner

“…<italic>Conclusions:</italic> The observed increase in preferred walking speed, reduction in metabolic cost of transport, and improved performance on clinical tests of mobility highlights the potentially transformative nature of this novel therapy; the rate at which this intervention elicited improved function was 3 &#x2013; 6 times greater than what has been reported previously.…”
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Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patien... by Rahul Soangra, Marybeth Grant-Beuttler, Harriet Chang, Raymond Y. Wang

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FRET-based reporter assesses lysosomal DNA-degradation ability in live cells by Jared Morse, Ka Ho Leung

“…Therefore, assessing lysosomal function is vital for advancing disease understanding and guiding therapeutic development. …”
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