Habitat Heterogeneity of Nitrogen and Phosphorus Cycling Functional Genes in Rhizosphere Microorganisms of <i>Pinus tabuliformis</i> in Qinling Mountains, China by Hang Yang, Yue Pang, Ying Yang, Dexiang Wang, Yuchao Wang

“…Specifically, slope environments showed an enhanced gene abundance associated with denitrification, nitrogen fixation, nitrification, assimilatory/dissimilatory nitrate reduction, and nitrogen transport processes, along with the superior expression of genes related to inorganic/organic phosphorus metabolism, phosphorus transport, and regulatory gene expression. …”
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Characterizing the Endophytic Microbiome and Microbial Functional Assemblages Associated with Fengtang Plum (<i>Prunus salicina</i> Lindl.) Development and Resistance by Jiqing Lei, Yinna Shi, Hong Li, Rui Wang

“…This study elucidates microbial community succession patterns during Fengtang plum development; notably, functional predictions were inferred from 16S/ITS sequencing data rather than direct metagenomic or metatranscriptomic analyses, thus limiting mechanistic interpretations, though future work integrating multi-omics approaches would strengthen functional insights.…”
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Insights into the role of GhCYP and GhTPS in the gossypol biosynthesis pathway via a multiomics and functional-based approach in cotton by Teame Gereziher Mehari, Marijana Skorić, Hui Fang, Kai Wang, Fang Liu, Tesfay Araya, Branislav Šiler, Dengbing Yao, Baohua Wang

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Chicken GLUT4 function via enhancing mitochondrial oxidative phosphorylation and inhibiting ribosome pathway in skeletal muscle satellite cells by Lin Zhang, Pengna Luo, Huihong Li, Yuxian Pan, Huaiyong Zhang, Xuemeng Si, Wen Chen, Yanqun Huang

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Liver‐directed gene therapy for ornithine aminotransferase deficiency by Iolanda Boffa, Elena Polishchuk, Lucia De Stefano, Fabio Dell'Aquila, Edoardo Nusco, Elena Marrocco, Matteo Audano, Silvia Pedretti, Marianna Caterino, Ilaria Bellezza, Margherita Ruoppolo, Nico Mitro, Barbara Cellini, Alberto Auricchio, Nicola Brunetti‐Pierri

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Protective Effect of Low-molecular-weight Fucoidan on Lead-induced Oxidative Damage in HepG2 Cells Based on Cellular Metabolomics by Fan YU, Na LI, Yingying GUO, Xinyue DAI, Wenjia ZHU, Lin YAO, Yanhua JIANG, Lianzhu WANG

“…Enrichment analysis of key metabolites regulated by F1 indicated that F1 primarily influenced several metabolic pathways involved in redox functions, such as D-glutamine and D-glutamate metabolism; alanine, aspartate, and glutamate metabolism; selenium compound metabolism; and arginine biosynthesis. …”
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Changes in Cardiopulmonary Capacity Parameters after Surgery: A Pilot Study Exploring the Link between Heart Function and Knee Surgery by Andrea Segreti, Chiara Fossati, Luigi Maria Monticelli, Daniele Valente, Dajana Polito, Emiliano Guerra, Andrea Zampoli, Giorgio Albimonti, Biagio Zampogna, Sebastiano Vasta, Rocco Papalia, Raffaele Antonelli Incalzi, Fabio Pigozzi, Francesco Grigioni

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Mitochonic acid 5 increases boar sperm quality by mitigating mitochondrial dysfunction by Ruyuan Wang, Adedeji O. Adetunji, Lingjiang Min, Zhendong Zhu

“…Consequently, MA-5 and PQQ play a role in maintaining sperm quality and mitochondrial function and can help in boar sperm preservation and artificial insemination (AI) practices.…”
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Dual-purpose elemental sulfur for capturing and accelerating biodegradation of petroleum hydrocarbons in anaerobic environment by Qian Zhao, Chengmei Liao, Enli Jiang, Xuejun Yan, Huijuan Su, Lili Tian, Nan Li, Fernanda Leite Lobo, Xin Wang

“…Consecutive subcultures combined with untargeted metabolomics analysis revealed that bacteria capable of dissimilatory sulfur reduction enhanced the fermentation process. These bacteria provided electrons to the metabolic network, which facilitated the mineralization of petroleum hydrocarbons. …”
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Courtship Is a Major Factor of Mating‐Shortened Male Lifespan in an Egg Parasitoid by Zi‐Yin Wang, Jing Li, Jia‐Min Tang, Lan‐Feng Qiu, Hao‐Yuan Hu, Peng‐Cheng Liu

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ВЛИЯНИЕ ФУНКЦИ ПЕЧЕНИ НА ФАРМАКОКИНЕТИКУ β-БЛОКАТОРОВ У БОЛЬНЫХ С ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА И СОЧЕТАННОЙ ПАТОЛОГИЕЙ... by Л. С. Литвинова, С. В. Бабак, Е. В. Кириенкова, А. А. Корженков, Н. И. Самаров, О. Л. Носарева, Т. С. Прохоренко, Е. В. Коновалова, В. Д. Якушина, А. И. Дмитриева, Ю. В. Колобовникова, В. А. Серебрякова, С. П. Чумакова, А. Е. Неймарк, Н. Л. Карабицкая, А. Л. Хохлов, А. Е. Мирошников, Д. П. Комаров

“…Terminal stages of liver fibrosis characterized by marked reduction of effector T cell function and activity of cells with the potential suppressor (CD4+CD25+), and B-lymphocytes and NK-cells (CD16+SD56+), which play the main role in a cascade of liver damage. …”
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The commonly used antibiotic streptomycin reduces protein synthesis and differentiation in cultured C2C12 myotubes by Chuqi He, Moritz Eggelbusch, Jelle Y. Huijts, Andi Shi, Gerard J. deWit, Carla Offringa, Richard T. Jaspers, Rob C. I. Wüst

“…Because streptomycin inhibits bacterial protein synthesis, streptomycin might also have off‐target effects on muscle cell function. Here, we studied the effect of streptomycin on C2C12 myoblasts, myofiber growth, and metabolism. …”
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The impacts of polystyrene microplastics on development, energy transfer and nutrient cycling of biofilms: A comprehensive chronic toxicity study by Shuangshuang Li, Duo Xu, Yu Zheng, Heng Liu, Yan Song, Mingcan Cai, Chun Wang

“…To address this research gap, we investigated the impact of polystyrene microplastics (PS-MPs) on biofilm growth and development, with a particular focus on their effects on functional metabolism in freshwater environments. Using controlled long-term experiments, we explored the influence of PS-MPs at concentrations of 1, 10, and 100 mg/L over 52 days on microbial community structure, alpha and beta diversity and functional potential. …”
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Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages by Boping Jing, Yu Gao, Lufang Wang, Feng Guo, Dawei Jiang, Saimei Qin, Mengrong He, Ying Bai, Rui An, Mingxing Xie, Li Zhang

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Febuxostat Improves Postprandial Glucose Regulation and Insulin Sensitivity in Hyperuricemic Individuals with Prediabetes or Newly Diagnosed Type 2 Diabetes: A Prospective Cohort S... by Liu S, Liu Q, Gu R, Wu M, Meng S, Yan L, Chen Q, Zhu C, Chen S, Xu B, Liu F, Chen H

“…This study aimed to investigated the impact of the urate-lowering drug febuxostat on blood glucose levels, insulin sensitivity, and β-cell function in subjects with HUA who present with normoglycemia, prediabetes, or newly diagnosed type 2 diabetes (T2DM).Methods: We assessed the glucose metabolism of participants with HUA using a 3-h oral glucose tolerance test (OGTT). …”
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The combined effects of ursodesoxycholic acid and quercetin on liver health and cardiac function in patients with non-alcoholic fatty liver disease and atrial fibrillation by O. B. Teslenko, S. V. Fedorov, M. V. Bielinskyi, A. S. Herashchenko, I. V. Stoika

“…Fibrosis stages also shifted after treatment, with group 3 showing a marked reduction in progressive fibrosis. Groups 2 and 3 also showed significant reductions in steatosis levels, with an increase in the proportion of patients without steatosis. …”
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P-16 UNLOCKING S-PINDOLOL'S POTENTIAL FOR MASLD: BENEFICIAL EFFECTS ON MUSCLE MASS AND FUNCTION AND LIVER HISTOLOGY IN WESTERN- DIET FED MICE by Daniel Cabrera, Loreto Aguilar, Faride Saud, Lisbell Estrada, Marcelo Andia, Marco Arrese, Juan Pablo Arab, Luis Antonio Diaz, Francisco Barrera, Rene Baudrand, Claudio Cabello-Verrugio

“…Conflict of interest: No Introduction and Objectives: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is linked to sarcopenia, which worsens disease's prognosis. …”
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High-throughput sequencing-based study on bacterial community structure and functional prediction of fermented bean curd from different regions in China by Xue Feng, Zhao Dong, Teng Hao

“…Additionally, significant variations were observed in functions such as nitrate reduction, nitrogen respiration, and nitrate respiration among different samples, suggesting that microbial diversity in nitrogen metabolism may influence the safety and quality of sufu. …”
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GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

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Effect of taking a dietary supplement containing Lactobacillus delbrueckii subsp. bulgaricus on clinical manifestations of functional dyspepsia and patients’ quality of life by I.G. Paliy, S.V. Zaika, O.O. Ksenchyn, I.V. Chernova

“…There is growing evidence that small intestinal microbiota plays a certain role in the pathophysiology of functional dyspepsia. Research aim: to study the effect of a product containing lyophilized lactic acid bacteria Lactobacillus delbrueckii subsp. bulgaricus strain 9702 (IMV B-7085) and its metabolic products on the clinical manifestations of the disease and quality of life of patients with functional dyspepsia. …”
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