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  1. 361
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    The Effect of Liv.52 DS in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): A Pilot, Randomized, Double-Blind, Placebo-Controlled, Clinical Study by Jalihal U, Nanda RA, Katariya K, Ramanathan B, Kumawat R

    Published 2025-08-01
    “…Considering the preliminary trend of hepatoprotective function of Liv.52 DS, the present study was conducted to explore its role in MAFLD.Patients and Methods: This randomized, double-blind, placebo-controlled, prospective, multicenter study was performed at four tertiary care hospitals in India. …”
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  3. 363

    Effects of Trimetazidine Combined with Atorvastatin on Cardiac Function in Patients with Stable Angina Pectoris of Coronary Heart Disease by Zhang N, Ren Y, Qin D, Yang X, Chen Z, Zhao L

    Published 2025-04-01
    “…Cardiac function parameters improved in both groups, with greater reductions in LVEDD and NT-proBNP and greater increases in LVEF and 6MWD in the observation group (P< 0.05). …”
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    Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT‐787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial by Thomas Capozza, Jennifer Burkey, Jeroen Van De Wetering, Reinhold Kerb, Jennifer Callahan, Ludmila Kryzhanovskaya, Mary Erickson

    Published 2025-05-01
    “…In preclinical/clinical studies, semisynthetic bile acid‐derived FXR agonists markedly improved hepatic function in various conditions. INT‐787, a novel hydrophilic semisynthetic bile acid FXR agonist, has demonstrated a reduction in inflammatory and fibrotic markers and regulation of bile acid/lipid metabolism. …”
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    Article
  7. 367

    Effect of a multidisciplinary lifestyle intervention on body composition in people with osteoarthritis: Secondary analysis of the “Plants for Joints” randomized controlled trial... by C.A. Wagenaar, W. Walrabenstein, C.S. de Jonge, M. Bisschops, M. van der Leeden, M. van der Esch, P.J.M. Weijs, M.A. Troelstra, M.A. Korteweg, A.J. Nederveen, D. van Schaardenburg

    Published 2024-12-01
    “…Objective: The Plants for Joints (PFJ) intervention significantly improved pain, stiffness, and physical function, and metabolic outcomes, in people with metabolic syndrome-associated osteoarthritis (MSOA). …”
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    Article
  8. 368

    The Regulatory Role of EvfG Through Coordinated Control of Flagellar Biosynthesis and Energy Metabolism in Porcine Extraintestinal Pathogenic <i>Escherichia coli</i> (ExPEC) by Bingbing Zong, Peiyi Wang, Wei Liu, Aihua Wu, Yong Xiao, Shulin Fu, Yinsheng Qiu, Yanyan Zhang, Wentong Liu

    Published 2025-07-01
    “…The metabolome profile and functional annotation analyses indicated that the impaired motility of Δ<i>evfG</i> was connected to the downregulation of the expression levels of genes associated with the energy metabolism pathway and flagellar assembly. …”
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  9. 369

    Sesame oil improves biomarkers of glycemic control in women with metabolic dysfunction-associated steatotic liver disease: a randomized, double-blind, controlled clinical trial by Masoumeh Atefi, Hamid Vahedi, Mina Darand, Mohammad Hassan Entezari

    Published 2025-07-01
    “…Abstract Aim This study aimed to investigate whether sesame oil (SO) consumption could improve biomarkers of glycemic control, inflammation, and oxidative stress in women with metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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    Persistent functional and taxonomic groups dominate an 8,000-year sedimentary sequence from Lake Cadagno, Switzerland by Paula Rodriguez, Jasmine S. Berg, Longhui Deng, Longhui Deng, Hendrik Vogel, Michal Okoniewski, Mark A. Lever, Mark A. Lever, Cara Magnabosco

    Published 2025-02-01
    “…Despite these dramatic changes in taxonomic community composition and sediment geochemistry throughout the sediment core, higher-order functional categories and metabolic marker gene abundances remain relatively consistent and indicate a microbial community capable of carbon fixation, fermentation, dissimilatory sulfate reduction and dissimilatory nitrate reduction to ammonium. …”
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    Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

    Published 2025-01-01
    “…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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  16. 376

    Low Ventricular Stiffness Is Associated With Suboptimal Outcomes in Patients With a Single Right Ventricle After the Fontan Operation: A Novel Phenotype by Shahryar M. Chowdhury, Andrew M. Atz, Eric M. Graham, Varsha M. Bandisode, John F. Rhodes, Arni C. Nutting, Carolyn Taylor, Andrew Savage, Marc Hassid, Minoo Kavarana, Donald Menick

    Published 2024-09-01
    “…The goal of this study was to perform a comprehensive assessment of diastolic function in pre‐Fontan patients with an SRV using invasive reference‐standard measures and determine their associations with post‐Fontan outcomes. …”
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  17. 377

    Redox regulation for sustainable water purification and risk management by Ai-Jie Wang, Rui-Feng Yan, Ke Shi, Hao-Yi Cheng, Jing-Long Han, Bin Liang

    Published 2025-05-01
    “…However, conventional biological or chemical oxidation treatment often fails to efficiently or purposefully cleave key functional groups, which leads to unsatisfactory performance of biological reactions or excessive chemical oxidation costs. …”
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  18. 378

    The Effects of Denosumab Treatment on Pain and Function Beyond Bone Density in Patients With Postmenopausal Osteoporosis: A Prospective Study by Miao Zheng, Xiong‐Yi Wang, Ke‐Yu Zhu, Si‐Min Yun, Yi‐Ke Wang, Cheng‐Wei Weng, Dong‐Zhang, Qi Wei, You‐Jia Xu

    Published 2025-06-01
    “…Pain (Numerical Rating Scale, NRS), function (Oswestry Disability Index, ODI), bone metabolic markers, and BMD were assessed at baseline, 6, and 12 months posttreatment. …”
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  19. 379

    Exploring the potential of anthocyanin-infused fermented beverages for sustainable health solutions: A pathway to functional food development by Büşra Yusufoğlu, Yasemin Açar, Gizem Kezer, Sina Zargarchi, Kerem Mertoglu, Tuba Esatbeyoglu

    Published 2025-12-01
    “…This review particularly highlights the health promoting potential of anthocyanin-rich fermented dairy and non-dairy fermented beverages such as kefir, kombucha, and kvass focusing on their health benefits such as cognitive function, type 2 diabetes (T2DM) and cancer. And also, emphasizes the functional roles of beverages in gut microbiota modulation, metabolic and neurotransmitter regulation, oxidative stress reduction and signaling pathways (e.g., NF-κB, PI3K/AKT). …”
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  20. 380

    Synergistic effects of berberine and curcumin-loaded chitosan nanoparticles in Nile tilapia: mitigating high-carbohydrate diet-induced metabolic dysfunction, hepatic injury, and im... by Ekramy Elmorsy, Ali A. El-Raghi, Ibrahim T. El-Ratel, Mahmoud A. Hassan, Helal F. Hetta, Mohamed E. Mohamed, Kasim S. Abass, Samah F. Ibrahim, Heba Allah M. Elbaghdady

    Published 2025-12-01
    “…The B-CR-CHNPs treatment significantly enhanced growth, feed utilisation, protein efficiency, digestive enzyme activities, blood protein levels, liver function, and lipid metabolism compared to the HCD group (p < 0.05). …”
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