Live Effects of Anodal and Cathodal Transcranial Direct Current Stimulation on Brain Metabolism in a Patient with Typical Hemorrhagic Stroke: A Case Study by Giuseppe Reale, Augusto Fusco, Fabrizio Cocciolillo, Vincenza Amoruso, Davide Glorioso, Maria Caputo, Maria Lucia Calcagni, Luca Padua

“…Baseline PET examination revealed marked hypometabolism of the right nucleo-capsular hemorrhagic lesion; at T1, an increase in brain metabolism was shown in the stimulated hemisphere and unexpectedly in the non-stimulated hemisphere; at T2, a reduction in metabolism was documented in the hemisphere ipsilateral to the inhibiting current applied by tDCS. …”
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Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology by Monique Marylin Alves de Almeida, Yves De Repentigny, Sabrina Gagnon, Emma R Sutton, Rashmi Kothary

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Comparative study of yogic practices and dietary modifications on biochemical variables among middle-aged women on metabolic dysfunction – Associated steatotic liver disease by S. Selva Sundari, C. V. Jayanthy, S. Natarajan

“…Results: The study revealed that the combined Yoga and Diet intervention led to a statistically significant improvement in liver function (alanine aminotransferase, F(2,17)=15.15, p<0.05) and glycemic control (fasting glucose, F(2,17)=6.64, p<0.05) among MAFLD participants, with the Yoga+Diet group showing the greatest mean reductions (-1.43 U/L and -37.06 mg/dL respectively). …”
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Hericium erinaceus insoluble dietary fiber alleviates obesity induced by high-fat diet through regulating the metabolic pathway influenced by gut microbiota by Guoze Wang, Qin Zhou, Binbin Wang, Xiang Tan, Peng Luo, Qun Huang, Lin Shi, Xin Li

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Functional effects of operations for malignant gastric neoplasms: prevention, diagnosis and treatment of post-gastrectomy disorders by A. V. Chaika, V. M. Khomyakov, A. B. Ryabov

“…Three basic groups of disorders are defined: disorders related to impaired organ anatomy; disorders caused by change in anatomical and physiological interrelations and developing as a compensatory response (mostly of functional origin); metabolic disorders. Development of inflammatory and of fibrotic anastomotic strictures and stenoses, erosions and/or ulcers, as well as obstruction caused by intestinal loop in relation or peritoneal adhesions make conservative treatment ineffective that require endoscopic or open surgical approaches: bougieurage, stenting or surgical reconstruction. …”
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MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study by Shengbo Yang, Litao Zhang, Mingli Hu, Weina He

“…Mediation analysis revealed that Simpson diversity partially mediated the relationship between MIND score and liver health indicators, suggesting a role for gut microbial diversity in modulating hepatic outcomes.ConclusionGreater adherence to the MIND diet was associated with indicators of better liver function, lower systemic inflammation, and improved metabolic health, and a more favorable gut microbiota composition in adults with MASLD.…”
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Higher hemoglobin levels are associated with impaired left ventricular global strains in metabolic syndrome: a 3.0 T CMR feature tracking study by Xue Li, Shi-Qin Yu, Zhi-Gang Yang, Bi-Yue Hu, Ke Shi, Jing Wang, Xue-Ming Li, Ge Zhang, Wen-Rong Li, Rong Xu, Yuan Li

“…Abstract Background Metabolic syndrome (MetS) is a known contributor to increased cardiovascular risk and all-cause mortality. …”
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Genome-centric metagenomics provides insights into the core microbial community and functional profiles of biofloc aquaculture by Meora Rajeev, Ilsuk Jung, Ilnam Kang, Jang-Cheon Cho

“…Conversely, genes associated with heterotrophic nitrification, anaerobic ammonium oxidation, assimilatory nitrate reduction, and sulfate reduction were undetected. Members of Rhodobacteraceae emerged as the most abundant and metabolically versatile taxa in this intriguing community. …”
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Impact of rosuvastatin on the memory potential and functionality of CD8+ T cells from people with HIVResearch in context by Federico Perdomo-Celis, Caroline Passaes, Valérie Monceaux, Olivier Lambotte, Dominique Costagliola, Mathieu F. Chevalier, Laurence Weiss, Asier Sáez-Cirión

“…The superior CD8+ T cell functionality after rosuvastatin treatment was associated with intrinsic metabolic changes, including the decrease of fatty acid uptake, as well as a reduction in effector/exhaustion markers. …”
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Effects of SLC6A8 mutation-induced creatine deficiency on cellular function in fibroblasts by Shingo Ito, Tatsuki Uemura, Ayaka Miyano, Hiroko Shimbo, Takeshi Masuda, Tomohide Goto, Hitoshi Osaka, Takahito Wada, Sumio Ohtsuki

“…In this study, we investigated the consequences of the G561R mutation by examining fibroblasts using proteomics and functional assays. We observed severe intracellular creatine deficiency (> 90% reduction), leading to impaired energy metabolism (low ATP and high ADP/ATP). …”
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Exogenous proline enhances salt acclimation in soybean seedlings: Modifying physicochemical properties and controlling proline metabolism through the ornithine-glutamate dual pathw... by Lei Yan, Mu Lu, Muhammad Riaz, Kaiqing Tong, Hualong Yu, Guang Gao, Yusheng Niu

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Multiple strategies association revealed functional candidate FASN gene for fatty acid composition in cattle by Bo Zhu, Tianzhen Wang, Qunhao Niu, Zezhao Wang, El Hamidi Hay, Lei Xu, Yan Chen, Lupei Zhang, Xue Gao, Huijiang Gao, Yang Cao, Yumin Zhao, Lingyang Xu, Junya Li

“…We investigated potential functional candidate genes for FA in beef cattle by integrating genomic and transcriptomic dataset through multiple strategies. …”
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Framework for Personalizing Wearable Devices Using Real-Time Physiological Measures by Prakyath Kantharaju, Sai Siddarth Vakacherla, Michael Jacobson, Hyeongkeun Jeong, Meet Nikunj Mevada, Xingyuan Zhou, Matthew J. Major, Myunghee Kim

“…This resulted in a 5.3&#x0025; and 18.1&#x0025; reduction in metabolic cost for walking for two individuals with transtibial amputation, compared to the weight-based assistance. …”
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Role of sortase-assembled Ebp pili in Enterococcus faecalis adhesion to iron oxides and its impact on extracellular electron transfer by Foo Kiong Ho, Ling Ning Lam, Artur Matysik, Thomas Dean Watts, Jun Jie Wong, Kelvin Kian Long Chong, Pei Yi Choo, Joe Tolar, Pui Man Low, Zhi Sheng Chua, Jason J. Paxman, Begoña Heras, Enrico Marsili, Caroline M. Ajo-Franklin, Kimberly A. Kline

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Plastic Responses of <i>Iris pumila</i> Functional and Mechanistic Leaf Traits to Experimental Warming by Katarina Hočevar, Ana Vuleta, Sanja Manitašević Jovanović

“…SLA and SD increased at higher temperatures, promoting photosynthesis and gas exchange, while reductions in SLWC, LDMC, LT, and chlorophyll content suggest a trade-off in favor of growth and metabolic activity over structural investment. …”
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Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. by Raphael Souza Pavani, Marcelo Santos da Silva, Carlos Alexandre Henrique Fernandes, Flavia Souza Morini, Christiane Bezerra Araujo, Marcos Roberto de Mattos Fontes, Osvaldo Augusto Sant'Anna, Carlos Renato Machado, Maria Isabel Cano, Stenio Perdigão Fragoso, Maria Carolina Elias

“…Here, we demonstrate experimentally that the T. cruzi RPA complex interacts with DNA via RPA-1 and is directly related to canonical functions, such as DNA replication and DNA damage response. …”
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The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study by Miłosz Miedziaszczyk, Marek Karczewski, Ilona Idasiak-Piechocka

“…Abstract Tacrolimus is metabolized in the liver with the participation of cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). …”
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GDNF overexpression in astrocytes enhances branching and partially preserves hippocampal function in an Alzheimer’s rat model by Ana Abril Vidal Escobedo, Facundo Peralta, Gustavo Ramón Morel, Martino Avallone, Tomas Björklund, Paula Cecilia Reggiani, Joaquín Pardo

“…These findings demonstrate the capacity of the AAV-GFAP-GDNF-TdTom construct to induce astrocytic branching and partially preserve memory function. They also underscore its partial therapeutic potential in a neuroinflammatory, metabolically compromised and neurodegenerative context.…”
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Tyrosine 67 Phosphorylation Controls Respiration and Limits the Apoptotic Functions of Cytochrome <i>c</i> by Junmei Wan, Paul T. Morse, Matthew P. Zurek, Alice A. Turner, Asmita Vaishnav, Arthur R. Salomon, Brian F. P. Edwards, Tasnim Arroum, Maik Hüttemann

“…Phosphomimetic Y67E replacement led to an almost complete loss of cardiolipin peroxidase activity, pointing to a central role of Y67 for this catalytic function of Cyt<i>c</i>. In intact cells, phosphomimetic replacement leads to a reduction in cell respiration, mitochondrial membrane potential, and ROS levels. …”
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Therapeutic potential of zinc 64Zn aspartate for obesity management: impact on oxidative stress, lipid metabolism, pancreas and liver in high-calorie diet model by Max Temnik, Sergey Gurin, Alexandr Balakin, Roman Byshovets, Olesia Kalmukova, Tetiana Vovk, Tetiana Halenova, Nataliia Raksha, Tetyana Falalyeyeva, Olexiy Savchuk

“…Maintaining adequate zinc levels is essential for overall metabolic health and proper functioning of these vital systems. …”
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