Effect of midlife exercise on lipid metabolism in aging mice: comparable to lifelong exercise, better than ceasing midlife exercise by Ling Yang, Tuanhui Peng, Xu Yan, Pengjie Lin

“…Moderate Intensity Continuous Training exercise sessions were conducted three times per week, with each session lasting 50 min; after exercise interventions until 72 weeks of age, the following parameters were measured: body morphology, exercise capacity, blood lipid, liver fat content, liver function, expression of liver lipid metabolism-related genes and endoplasmic reticulum stress-related genes, and activities of liver metabolism enzymes. …”
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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

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Study of the effect of human placenta hydrolysate in a new model of metabolic-associated fatty liver disease with iron overload by T. E. Bogacheva, O. A. Gromova, I. Yu. Torshin, V. I. Demidov, A. G. Kalacheva, A. A. Garanin, I. V. Gogoleva, L. E. Fedotova, O. A. Limanova, А. N. Mnatsakanyan, N. Yu. Zhidomorov, T. R. Grishina

“…Background. The combination of metabolic-associated fatty liver disease (МAFLD) with iron overload occurs in approximately 1/3 of patients and is extremely difficult to treat. …”
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Metagenomic Exploration Uncovers Several Novel ‘Candidatus’ Species Involved in Acetate Metabolism in High‐Ammonia Thermophilic Biogas Processes by George B. Cheng, Erik Bongcam‐Rudloff, Anna Schnürer

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Comparative transcriptomic analysis reveals the important role of hepatic fatty acid metabolism in the acute heat stress response in chickens by Zi Mei, Zhenquan Song, Haobo Zhou, Bin Zheng, Yiwei Xiong, Zheya Sheng, Yanzhang Gong

“…Functional validation in primary hepatocytes demonstrated that overexpression of FASN attenuated heat stress-induced reductions in triglyceride levels. …”
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Effects of Correction of Acidosis on Body Composition in Patients Suffering from Chronic Kidney Disease on Haemodialysis: A Prospective Interventional Study by Atul Sajgure, Chetan Phadke, Charan Bale, Pavan Wakhare, Nilesh Shinde, Vivek Biradar, Shreeharsh Godbole, Tushar Dighe

“…Conclusion: The correction of acidosis improved metabolic parameters, resulting in an increase in fat percentage and a reduction in ECW and third space water without intracellular dehydration. …”
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NF-κB inactivation in myeloid cell leads to reprogramming of whole-body energy metabolism in response to high-fat diet by Xianghong Wang, Zhe Yang, Xin Ye, Owen P. McGuinness, Hengwen Yang, Hongyun Lu, Jianping Ye

“…The KO mice showed a reduction in metabolic rate after LPS challenge for accelerated decrease of oxygen consumption. …”
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Xanthine oxidase inhibitors in asymptomatic hyperuricemia by O. V. Zhelyabina, M. S. Eliseev

“…The use of xanthine oxidase (XO) inhibitors in a number of trials was accompanied by a reduction in the risk of CVD and by an improvement in renal function. …”
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Biogeography and ecological functions of underestimated CPR and DPANN in acid mine drainage sediments by Sheng-Xuan Peng, Shao-Ming Gao, Zhi-Liang Lin, Zhen-Hao Luo, Si-Yu Zhang, Wen-Sheng Shu, Fangang Meng, Li-Nan Huang

“…Although both groups might be capable of iron reduction through a flavin-based extracellular electron transfer mechanism, significant differences are found in their metabolic capabilities (with complex carbon degradation and chitin degradation being more prevalent in CPR whereas fermentation and acetate production being enriched in DPANN), indicating potential niche differentiation. …”
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Lysophospholipid metabolism, clinical characteristics, and artificial intelligence-based quantitative assessments of chest CT in patients with stable COPD and healthy smokers by Qiqiang Zhou, Lvxinhe Xing, Mi Ma, Bianba Qiongda, Deyuan Li, Ping Wang, Yahong Chen, Ying Liang, Meilang ChuTso, Yongchang Sun

“…The reduction in these three LPCs was associated with impaired pulmonary function and were also linked to a greater extent of emphysema and interstitial lung abnormalities.…”
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Ancient Grains as Functional Foods: Integrating Traditional Knowledge with Contemporary Nutritional Science by Jude Juventus Aweya, Drupat Sharma, Ravneet Kaur Bajwa, Bliss Earnest, Hajer Krache, Mohammed H. Moghadasian

“…Their health-promoting effects are underpinned by multiple interconnected mechanisms, including the reduction in oxidative stress, modulation of inflammatory pathways, regulation of glucose and lipid metabolism, support for mitochondrial function, and enhancement of gut microbiota composition. …”
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Melatonin-induced Bacillus tequilensis enhanced the disease resistance of Camellia oleifera against anthracnose by modulating cell wall and phenylpropanoid metabolism by Aiting Zhou, Aiting Zhou, Huiqin Zhou, Huiqin Zhou, Ruiqi Peng, Ruiqi Peng, Di Liu, Di Liu, Jianrong Wu, Jianrong Wu, Jia Deng, Jia Deng, Fang Wang, Fang Wang

“…In addition, MT-DZY 6715 promoted the expression of secondary metabolism-related genes, such as PAL, CAL, Laccase, HCT, and CHI, and inhibited the activity of enzymes related to cell wall degradation (pectinase and cellulase), thereby coordinating and enhancing the accumulation of secondary metabolites and strengthening the mechanical properties of the cell wall.DiscussionThe results of this study demonstrate that MT-DZY 6715 enhances the resistance of C. oleifera to anthracnose by modulating leaf morphology, regulating stomatal function, and promoting the accumulation of secondary metabolites. …”
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Comparative analysis of combined exercise programs in middle-aged obese males: impact on energy expenditure, body composition, and metabolic rate by Gerasimos V. Grivas

“…Additionally, respiratory function showed a large improvement. No significant differences were observed between SCG and ICG in energy expenditure, resting metabolic rate, total daily energy expenditure, macronutrient composition, or health indices after the intervention (p > 0.05).ConclusionIn conclusion, both SCG and ICG are effective strategies for improving metabolic health, respiratory function, and body composition in middle-aged obese males. …”
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Dietary resilience of termite gut microbiota and enzymatic function reflects feeding strategy by Letícia R. Menezes, João Paulo L. F. Cairo, Ana Maria Costa-Leonardo, Maria Teresa Pedrosa Silva Clerici, Isabela da Costa Barreto, Bianca Suriano Francisco dos Santos, Alberto Arab

“…Bioinformatic and statistical analyses were performed to assess diversity, taxonomic shifts, and functional predictions.ResultsSilvestritermes euamignathus maintained stable microbial composition and enzymatic activity across diets, whereas C. cumulans exhibited shifts in bacterial abundance and a marked reduction in enzymatic function when exposed to complex artificial diets. …”
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Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation by Maycon Tavares Emílio-Silva, Vinicius Peixoto Rodrigues, Mariana Moraes Fioravanti, Antonio Jesús Ruiz-Malagon, Matheus Naia Fioretto, Priscila Romano Raimundo, Rie Ohara, Renata Assunção, Gabriela Bueno, Felipe Lima Dario, Luis Antonio Justulin, Alba Rodríguez-Nogales, Lucia Regina Machado da Rocha, Júlio Gálvez, Júlio Gálvez, Clélia Akiko Hiruma-Lima

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Two novel Patescibacteria: Phycocordibacter aenigmaticus gen. nov. sp. nov. and Minusculum obligatum gen. nov. sp. nov., both associated with microalgae optimized for carbon dioxid... by Lauren Jonas, Yi-Ying Lee, Tsvetan Bachvaroff, Russell T. Hill, Yantao Li

“…P. aenigmaticus may also rely on elemental sulfur oxidation (sdo), partial nitrite reduction (nirK), and sulfur-related amino acid metabolism (SAMe → SAH). …”
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The peculiarities of adiponectin and resistin interrelationships with the components of metabolic syndrome in patients with coronary heart disease and concomitant nonalcoholic fatt... by N. S. Mykhailovska, L. Ye. Miniailenko

“…Objective: to investigate the interrelationships between adiponectin and resistin levels with the components of metabolic syndrome in patients with coronary heart disease and concomitant nonalcoholic fatty liver disease. …”
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Integrative analysis of bulk and single-cell transcriptomic data reveals novel insights into lipid metabolism and prognostic factors in hepatocellular carcinoma by Feiyu Qi, Guiming Zha, Yanfang Zhang, Sihua Liu, Yuhang Yang, Wanliang Sun, Dongdong Wang, Zhong Liu, Zheng Lu, Dengyong Zhang

“…This study investigated the status of lipid metabolism-related genes in HCC. Bulk transcriptomic and single-cell sequencing data for HCC were retrieved from public databases. …”
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Suppressing mitochondrial inner membrane protein (IMMT) inhibits the proliferation of breast cancer cells through mitochondrial remodeling and metabolic regulation by Li Liu, Qingqing Zhao, Daigang Xiong, Dan Li, Jie Du, Yunfei Huang, Yan Yang, Rui Chen

“…Mitochondria, as pivotal organelles, play a crucial role in the metabolic regulation of tumor cells, and their morphological and functional alterations are intricately linked to the biological characteristics of tumors. …”
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IFN-β production promotes metabolic rewiring and protection against oxidative stress in hepatitis delta virus-infected hepatocyte cultures by Olga A. Khomich, Patrick Giavalisco, Romain Parent, George S. Krasnov, Peter Tessarz, Philip Meuleman, Rani Burm, Natalia F. Zakirova, Jennifer Molle, Enkhtuul Batbold, Eyal Gottlieb, Fabien Zoulim, Alexander V. Ivanov, Birke Bartosch

“…Transcriptome analysis, isotope tracing and functional tests on differentiated, HDV-infected hepatocytes showed reduction of mitochondrial TCA cycle and respiratory activity and increases in serine, asparagine and glutathione synthesis. …”
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