High-Fat-Diet-Induced Metabolic Disorders: An Original Cause for Neurovascular Uncoupling Through the Imbalance of Glutamatergic Pathways by Manon Haas, Maud Petrault, Patrick Gele, Thavarak Ouk, Vincent Berezowski, Olivier Petrault, Michèle Bastide

“…<b>Conclusions:</b> This HFD-induced neurogliovascular uncoupling pathway offers therapeutic targets to consider for improving cerebral vasoactive functions while preventing peripheral metabolic disturbances.…”
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Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…Clenbuterol inclusion significantly improves growth performance and antioxidant defenses by modulating nrf2 signaling and reducing inflammatory response, reduces fatty acid synthesis, and enhances mitochondrial β-oxidation not only functioning as a lipid regulator and effectively alleviating fat accumulation in the liver but playing an essential role in the control of glucose metabolism by reducing hepatic glucose production in high-fat diet-fed Nile tilapias well.…”
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Comparison of the effects of umbilical cord cryoextract and lyophilized form on the adhesive, proliferative, and metabolic properties of various cell types by A. Kaverinska, V.Yu. Prokopiuk

“…This will facilitate its wider application in the stimulation of tissue regeneration and the restoration of functional activity in various organs.…”
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Metabolic profiling and insecticidal activities of Rosmarinus officinalis L. for the management of Aphis craccivora Koch and Planococcus lilacinus Cockerell by Urvashi Kashyap, S. G. Eswara Reddy

“…In the present investigation, chemical constituents, metabolic profile, and insecticidal activities of Rosmarinus officinalis L. …”
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FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice by Alba Irisarri, Ana Corral, Núria Perez-Salvador, Aina Bellver-Sanchis, Marta Ribalta-Vilella, Roger Bentanachs, Marta Alegret, Juan Carlos Laguna, Emma Barroso, Xavier Palomer, Daniel Ortuño-Sahagún, Manuel Vázquez-Carrera, Mercè Pallàs, Laura Herrero, Christian Griñán-Ferré

“…Abstract This study investigated the effects of fat mass and obesity-associated (FTO) inhibition on cognitive function and metabolic parameters of senescence-accelerated mouse prone 8 (SAMP8) mice fed a high-fat diet (HFD). …”
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Comparative metagenomics highlights the habitat-related diversity in taxonomic composition and metabolic potential of deep-sea sediment microbiota by Rui Lu, Denghui Li, Yang Guo, Zhen Cui, Zhanfei Wei, Guangyi Fan, Weijia Zhang, Yinzhao Wang, Ying Gu, Mo Han, Shanshan Liu, Liang Meng

“…Benthic ecosystems exhibit distinct microbial potentials for sulfate reduction, both assimilatory and dissimilatory sulfate reduction (ASR and DSR), in response to different environmental conditions. …”
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Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial by Naiiere Gharagozloo Hesari, Shahideh Jahanian Sadatmahalleh, Parvin Mohebbi, Malihe Nasiri, Ahmad Khosravi

“…The study assessed changes in MetS indices, quality of life (QoL), and sexual function before and after the intervention. Results After 8 weeks, the garlic group showed significant reductions in fasting blood sugar (FBS) by 10.5% (from 107.2 to 95.9 mg/dL; P < 0.001), triglycerides (TG) by 17.8% (P = 0.002), low-density lipoprotein cholesterol (LDL-C) by 14.2% (P < 0.001), total cholesterol (TC) by 12.6% (P < 0.001), and C-reactive protein (CRP) by 24.7% (P < 0.001), compared to the placebo group. …”
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The effect of Greek mountain tea extract and wheat germ extract on peripheral blood flow and eicosanoid metabolism in mammals by Pantano Licia, Hiroki Kento, Ono Ashiyu, Osada Yuta, Fujii Yasuyuki, Maiolino Luigi, Jacob Ursula M., Cammilleri Gaetano, Hippe Berit, Lo Dico Gianluigi M., Ferrantelli Vincenzo, Osakabe Naomi, Calabrese Vittorio

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Bovine colostrum-derived exosomes alleviate muscle degeneration by modulating gut microbiota and metabolic homeostasis in atrophy models by Minkyoung Kang, Bohyun Yun, Daye Mun, Sooah Kim, Kwangcheol Casey Jeong, Younghoon Kim, Sangnam Oh

“…This study aimed to evaluate the potential functional role of bovine colostrum-derived exosomes (BCE) in reducing muscle atrophy. …”
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Metabolic Variations in Bamboo Shoot Boiled Liquid During <i>Pediococcus pentosaceus</i> B49 Fermentation by Juqing Huang, Meng Sun, Xuefang Guan, Lingyue Zhong, Jie Li, Qi Wang, Shizhong Zhang

“…These findings elucidate metabolic regulation in BSBL fermentation, supporting development of functional fermented bamboo products.…”
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Short-term impact of tirzepatide on metabolic hypogonadism and body composition in patients with obesity: a controlled pilot study by Sandro La Vignera, Rossella Cannarella, Vincenzo Garofalo, Andrea Crafa, Federica Barbagallo, Rosita A. Condorelli, Aldo E. Calogero

“…These findings position TZP as a promising treatment for obese patients with functional hypogonadism arising from metabolic-related alterations.…”
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Role of Galactosylceramide Metabolism in Satellite Glial Cell Dysfunction and Neuron–Glia Interactions in Painful Diabetic Peripheral Neuropathy by Xin Xu, Yue Zhang, Shuo Li, Chenlong Liao, Xiaosheng Yang, Wenchuan Zhang

“…The PDPN group exhibited transcriptional activation and structural reorganization of SGCs, characterized by increased SGC abundance and glial activation, evidenced by elevated Gfap expression. Functional enrichment analyses revealed disruptions in sphingolipid metabolism, including marked reductions in GalCer levels. …”
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Utilizing Lactic Acid Bacteria to Improve Hyperlipidemia: A Comprehensive Analysis from Gut Microbiota to Metabolic Pathways by Changlu Ma, Chen Xu, Mumin Zheng, Shuwen Zhang, Qifeng Liu, Jiaping Lyu, Xiaoyang Pang, Yinghong Wang

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Fixed dose combination of perindopril with indapamide in primary prevention of cerebrovascular complications among patients with metabolic syndrome and arterial hypertension by V. B. Mychka, K. M. Mamyrbaeva, V. P. Masenko, V. B. Sergienko, I. E. Chazova

“…Noliprel® therapy in patients with AH and MS was associated with BP reduction, together with endothelial function improvement, peripheral tissue insulin sensitivity increase, and positive metabolic effects, that resulted in substantial improvement of cerebral perfusion.…”
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Harm reduction measures in a recreational gym user with anabolic androgenic steroid dependence: a case report in the context of current best clinical practice by Raphael Magnolini, Sofia Laura Bottoni, Helena Hammer, Joël Capraro, Philip Bruggmann, Oliver Senn

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Exploring ultrasound-induced metabolic attenuation in Lacticaseibacillus casei ATCC 393—A combined approach using traditional methods and flow cytometry by Irene Giordano, Mohammed Salman, Stefania Arioli, Diego Mora, Gianluigi Mauriello

“…Attenuation technologies applied to probiotics aim to modulate specific metabolic pathways, particularly acidification, while maintaining cell viability. …”
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INFLAMMATORY REACTIONS IN EXPERIMENTAL MYOCARDIAL DAMAGE by L. D. Khidirova, N. N. Mayanskaya

“…To study the role of hormonal and metabolic changes specific to myocardial infarction in the development of inflammatory reactions in the experimental non-coronarogenic myocardial damage. …”
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Functional tradeoffs underpin salinity-driven divergence in microbial community composition. by Chris L Dupont, John Larsson, Shibu Yooseph, Karolina Ininbergs, Johannes Goll, Johannes Asplund-Samuelsson, John P McCrow, Narin Celepli, Lisa Zeigler Allen, Martin Ekman, Andrew J Lucas, Åke Hagström, Mathangi Thiagarajan, Björn Brindefalk, Alexander R Richter, Anders F Andersson, Aaron Tenney, Daniel Lundin, Andrey Tovchigrechko, Johan A A Nylander, Daniel Brami, Jonathan H Badger, Andrew E Allen, Douglas B Rusch, Jeff Hoffman, Erling Norrby, Robert Friedman, Jarone Pinhassi, J Craig Venter, Birgitta Bergman

“…Multivariate statistical analyses showed that salinity is the main determinant of dramatic changes in microbial community composition, but also of large scale changes in core metabolic functions of bacteria. Strikingly, genetically and metabolically different pathways for key metabolic processes, such as respiration, biosynthesis of quinones and isoprenoids, glycolysis and osmolyte transport, were differentially abundant at high and low salinities. …”
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Multimodal Neuroimaging of Obesity: From Structural-Functional Mechanisms to Precision Interventions by Wenhua Liu, Na Li, Dongsheng Tang, Lang Qin, Zhiqiang Zhu

“…Purpose: Obesity’s metabolic consequences are well documented; however, its neurobiological underpinnings remain elusive. …”
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Role of endothelial dysfunction and circadian blood pressure profile disturbances in the development of cerebrovascular insufficiency among patients with metabolic syndrome by Yu. B. Lishmanov, N. Yu. Efimova, V. I. Chernov, I. Yu. Efimova, T. P. Kalashnikova

“…To assess the role of endothelial dysfunction and circadian blood pressure profile disturbances in the development of cerebrovascular insufficiency among patients with metabolic syndrome (MS). Material and methods. The study included 53 MS patients (8 men and 44 women; mean age 51,6+5,5 years), who underwent brain single-photon emission computed tomography, neuro-psychological assessment, 24-hour blood pressure monitoring (BPM), and brachial artery Doppler ultrasound, in order to assess endothelial function. …”
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