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  1. 701

    An HPLC-based Assay to Study the Activity of Cyclic Diadenosine Monophosphate (C-di-AMP) Synthase DisA from Mycobacterium smegmatis by Avisek Mahapa, Sudhanshu Gautam, Arti Rathore, Dipankar Chatterji

    Published 2024-12-01
    “…Besides the bacterial system, c-di-AMP signaling is also connected with the host cytoplasmic surveillance pathways (CSP) that induce type-I IFN responses through STING-mediated pathways. Additionally, c-di-AMP demonstrates potent adjuvant properties, particularly when administered alongside the Bacillus Calmette–Guérin (BCG) vaccine through mucosal routes. …”
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  2. 702

    Toward the Language MOOC (LMOOC’s) low dropout rate: The control-value theory of persistency in LMOOC (CVTPLMOOC) by Amir Reza Rahimi, Babak Daneshvar Ghorbani

    Published 2025-03-01
    “…The symmetrical part of the study validated the factorial structures of our conceptual theory in LMOOC and demonstrated that the higher the interaction between language learners, the more their perception of LMOOC content aligned with their objectives, the more persistence they displayed, and the lower the boredom level. Moreover, serial mediation analysis revealed that extrinsic value appraisal also mediated language learners' persistence and boredom in LMOOCs. …”
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  3. 703

    CD47/SIRPα axis: bridging innate and adaptive immunity by Sjoerd H van der Burg, Anneloes van Duijn, Ferenc A Scheeren

    Published 2022-07-01
    “…Interestingly, the CD47/SIRPα axis is also involved in T cell-mediated antitumor responses. In this perspective we provide an overview of recent studies showing how therapeutic blockade of the CD47/SIRPα axis improves the adaptive immune response. …”
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  4. 704

    South African Rheumatism and Arthritis Association 2024 guidelines for the use of biologic and targeted synthetic disease-modifying antirheumatic drugs by E van Duuren, J Potts, U Brijlal, S Botha, S Didi, K Makan, M van Dam, K Chinniah, B Hodkinson

    Published 2024-09-01
    “…It is recommended that b/tsDMARDs for immune-mediated inflammatory rheumatic diseases are prescribed by a rheumatologist, and all patients must be included in the South African Rheumatism and Arthritis Association biologic registry. …”
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  5. 705

    Empowering Lecturers Through Servant Leadership: The Influence of Digital Literacy and Cultural Adaptation by Agus Susanto, Elyzabeth Wijaya, Hendry Hendry, Septa Diana Nabella, Yandra Rivaldo

    Published 2024-12-01
    “… This study examines the impact of digital literacy and adaptable culture on lecturer performance, with servant leadership as a mediating variable. The Institute of Information Technology and Business executed the study, with several lecturers participating as responders. …”
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  6. 706

    Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

    Published 2025-02-01
    “…Results: NSAIDs demonstrate significant anticancer effects by targeting inflammation-mediated pathways. They exhibit promising outcomes in reducing metastasis, promoting apoptosis, and inhibiting tumor invasion and progression. …”
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  7. 707

    Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/-catenin signaling pathway by Tongke Sun, Dan Ma, Yang Song, Jing Hu, Ziqing Yang, Xu Wang, Jun Zhang

    Published 2025-02-01
    “…A 0.01 mM Sr 2+ concentration significantly enhanced hPDLSC proliferation and osteogenic differentiation. However, XAV939-mediated inhibition of the canonical Wnt/β-catenin pathway could reverse the Sr 2 + -induced osteogenic effects. …”
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  8. 708

    Introduction risk of fire ants through container cargo in ports: Data integration approach considering a logistic network. by Shota Homma, Daisuke Murakami, Shinya Hosokawa, Koji Kanefuji

    Published 2025-01-01
    “…Unlike natural dispersal, methods to address these issues have not yet been established, because the spatial correlation between ports based on the geographical distance is not assumed for human-mediated species introduction through container cargo. …”
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  9. 709

    Learn from international recommendations and experiences of countries that have successfully implemented monoclonal antibody prophylaxis for prevention of RSV infection by Sara Manti, Eugenio Baraldi

    Published 2025-02-01
    “…Abstract Respiratory syncytial virus (RSV)-mediated bronchiolitis causes a significant global health burden. …”
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  10. 710

    A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

    Published 2025-01-01
    “…Crustin, a widely-studied antimicrobial peptides (AMPs), has been proven to be involved in mediating innate immune responses against intruding pathogens. …”
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  11. 711

    Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans. by Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe

    Published 2004-10-01
    “…The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated alpha subunits of hypoxia-inducible factor (HIF). …”
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  12. 712

    Follistatin like-1 aggravates silica-induced mouse lung injury by Yinshan Fang, Si Zhang, Xiaohe Li, Fangxin Jiang, Qiao Ye, Wen Ning

    Published 2017-03-01
    “…The induced Fstl1 regulated inflammation response via activation of nod-like receptor family, pyrin domain containing 3v (NLRP3) inflammasome-mediated IL-1β production from macrophages. Meanwhile, Fstl1 promoted fibrosis via positive regulation of TGF-β1 signaling. …”
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