Paroxysmal sympathetic hyperactivity and refractory hypotension in Guillain-Barré syndrome with autoimmune encephalitis: a case report and literature review by Jun-Ping Wang, Yan-Bo He

“…Guillain-Barré syndrome (GBS) is an acute inflammatory peripheral nerve disorder mediated by autoimmune mechanisms. However, its co-occurrence with autoimmune encephalitis (AE) is rare. …”
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Educational insights into digital entrepreneurship: the influence of personality and innovation attitudes by João M. Lopes, Sofia Gomes, Elisabete Nogueira

“…However, this relationship becomes significant when the relationship between personality traits and digital entrepreneurial intention is mediated by an innovative digital attitude. Furthermore, the intensifying role of digital entrepreneurial education was demonstrated in converting students' innovative digital attitudes into their digital entrepreneurial intention. …”
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Supraspinal facilitation of painful stimuli by glutamatergic innervation from the retrosplenial to the anterior cingulate cortex. by Shun Hao, Man Xue, Qi-Yu Chen, Jinjin Wan, Yu-Jie Ma, Wantong Shi, Xuanying Chen, Xu-Hui Li, Jing-Shan Lu, Fang Xu, Guo-Qiang Bi, Wucheng Tao, Min Zhuo

“…This excitatory transmission is predominantly mediated by the postsynaptic AMPA receptors. Furthermore, the activation of the RSC-ACC projections through opto-/chemogenetics significantly facilitated the behavioral responses to both mechanical and thermal nociceptive stimuli in adult mice. …”
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Protocol for the intracerebral injection of AAV-α-synuclein plus poly(ADP-ribose) to generate a Parkinson’s disease monkey model by Shuyi Liu, Wei Si, Zhengbo Wang

“…We then detail a technique for the intracerebral administration of adeno-associated virus (AAV)-mediated overexpression of α-synuclein into the substantia nigra plus the injection of poly(ADP-ribose) (PAR) into the striatum.For complete details on the use and execution of this protocol, please refer to Liu et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Determining application rates of FYM and pressmud to improve soil health properties in salt degraded soils. by M L Dotaniya, M D Meena, R L Choudhary, M K Meena, V D Meena, H V Singh, R S Jat, R K Doutaniya, Kuldeep Kumar, Harpreet Singh, P K Rai

“…However, the key challenge is excessive concentration of salts. It adversely mediates the soil fertility parameters, physical properties and soil enzymatic activities. …”
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Inotersen to Treat Polyneuropathy Associated with Hereditary Transthyretin (hATTR) Amyloidosis by Christopher Robinson, Cynthia Pham, Alec M. Zamarripa, Chase S. Dugay, Christopher A. Lee, Amnon A. Berger, Avi Landman, Elyse M. Cornett, Hisham Kassem, Alan D. Kaye, Ivan Urits, Omar Viswanath, Latha Ganti

“…There are both acquired and hereditary forms of this disease, and this review focuses on the latter hereditary transthyretin-mediated (hATTR). hATTR affects about 50,000 individuals globally and mostly appears as one of three syndromes - cardiac, polyneuropathy, and oculoleptomeningeal. …”
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Proton-electron coupling and mixed conductivity in a hydrogen-bonded coordination polymer by Minju Park, Huiyeong Ju, Joohee Oh, Kwangmin Park, Hyunseob Lim, Seok Min Yoon, Intek Song

“…We demonstrate the practical implications of this mechanism by examining the humidity-dependent synaptic plasticity of Ni-BAND, showcasing how MPECs can expand into traditional MIEC applications while leveraging their unique proton-mediated advantages.…”
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Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers by Arni Thorlacius, Maksim Rulev, Oscar Sundberg, Anna Sundborger-Lunna

“…We also show that endophilin B1 efficiently permeabilizes negatively charged liposomes that contain mitochondria-specific lipid cardiolipin and propose a new model for Bax-mediated cell death.…”
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Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation by Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

“…Through comprehensive analysis, including RNA sequencing data from TCGA and functional assays, we observed that Ephexin1 promotes tumor proliferation and migration by activating the Wnt/β-catenin pathway. This effect was mediated by the interaction of Ephexin1 with Axin1, a critical component of the β-catenin destruction complex, which in turn enhanced the stability and activity of β-catenin in signaling pathways critical for tumor development. …”
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Eosinophilic esophagitis: literature review and original case presentation by V. T. Ivashkin, Ye. K. Baranskaya, V. O. Kaybysheva, Ye. V. Ivanova, Ye. D. Fedorov

“…Eosinophilic esophagitis is chronic immune antigen-mediated inflammatory disease of the esophagus with still obscure etiopathogenesis. …”
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Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Conclusion: It was found that increased expression of Axl, which is known to increase EMT-mediated metastasis in carcinogenesis, may be an indicator of local spread and poor prognosis in PDAC patients. …”
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Expanding Viral Diversity in Rice Fields by Next-Generation Sequencing by Wang Haoran, Chen Guoqing, Feng Guozhong

“…These analyses greatly expand our understanding of viruses in rice fields and provide valuable insights for developing efficient strategies to manage insect pests and virus-mediated rice diseases.…”
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A abstinência voluntária do consumo de carne pode ser compreendida como um princípio ético? by Marta Luciane Fischer, Andressa Luiza Cordeiro, Rafael Falvo Librelato

“…Thus, changing ethical conceptions requires a rational decision that should be performed by consolidated ethical principles and intermediated by a dialogue promoted by sciences such as Environmental Bioethics, which proposes to mediate complex, globalized and plural issues to seek consensual solutions for all involved in this and in the future generations.…”
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TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep. by Li-Xia Qiu, Qian Yu, Hua-Qian Zhou, Wen-Hua Fan, Jing-Jing Zheng, Yong-Lin Yang, Wen-Zhe Zhang, Xin Cao, Hua Yang

“…However, the mechanism by which proteins mediate the fetal development of secondary hair follicles remains unknown. …”
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Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis by Min Cao, Zhenhu Zhang, Qian Liu, Yuda Zhang

“…Conclusions: These 13 key genes may mediate the occurrence and development of KD through various processes such as immune regulation, inflammatory response, glucose metabolism, autophagy, and apoptosis, which provide valuable references for the diagnosis and treatment of KD.…”
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Plant volatiles play differential roles in pre and post alighting phases in a specialist phytophagous insect by Menacer, Kathleen, Hervé, Maxime, Lapeyre, Benoit, Vedrenne, Manon, Cortesero, Anne Marie

“…We aimed to identify VOCs that mediate attraction and oviposition behaviors of the cabbage root fly, and to distinguish whether their effect applies at distance or at contact. …”
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Acute particulate matter exposure diminishes executive cognitive functioning after four hours regardless of inhalation pathway by Thomas Faherty, Jane E. Raymond, Gordon McFiggans, Francis D. Pope

“…Inhalation method did not significantly mediate effects, suggesting that short-term PM pollution affects cognitive function through lung-brain mechanisms, either directly or indirectly.…”
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The role of IELTS teacher’s metapathy in IELTS candidates’ overall band score, language learning orientation, and active/passive motivation by Hamed Ghaemi, Robert Kirkpatrick

“…Additionally, the frequency of teacher-student interaction was found to mediate the relationship between teacher metapathy and students’ motivation levels. …”
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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…Results: NSAIDs demonstrate significant anticancer effects by targeting inflammation-mediated pathways. They exhibit promising outcomes in reducing metastasis, promoting apoptosis, and inhibiting tumor invasion and progression. …”
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Specialized contact sites regulate the fusion of chlamydial inclusion membranes by Christine Linton, Jordan Wesolowski, Anna Lobley, Toshiyuki Yamaji, Kentaro Hanada, Fabienne Paumet

“…Thus, our study demonstrates that Chlamydia-mediated membrane fusion is primarily regulated by specific structural domains in IncA and its local organization on the inclusion membrane, which is affected by the host cell lipid composition.…”
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