Immune-related adverse events with PD-1/PD-L1 inhibitors: insights from a real-world cohort of 2523 patients by Ting Yan, Minghui Long, Chaoyi Liu, Jiwen Zhang, Jiwen Zhang, Xingyu Wei, Xingyu Wei, Fei Li, Fei Li, Dehua Liao

“…IrAEs affected various organ systems, with endocrine toxicity (17.7%), hepatic toxicity (17.2%), and hematologic toxicity (11.4%) being the most common. 20.5% patients experienced multi-system irAEs. The average time for patients to develop irAEs was within four treatment cycles. …”
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The incidence of incomplete abortion and the prevalence of abortion-related morbidity in South African public hospitals, 2018 by D N Conco, J Levin, B Komane, K Blanchard, T Bessenaar, N G Nkosi, S Fonn

“…Globally, unsafe abortions remain a persistent, yet preventable, cause of maternal mortality. South Africa (SA) is internationally recognised for its progressive reproductive rights framework, supported by its Constitution and laws. …”
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Radiosensitizing capacity of fenofibrate in glioblastoma cells depends on lipid metabolism by Bayan Alkotub, Lisa Bauer, Ali Bashiri Dezfouli, Khouloud Hachani, Vasilis Ntziachristos, Gabriele Multhoff, Morteza Hasanzadeh Kafshgari

“…Despite advances in multimodal therapy approaches such as resection, chemotherapy and radiotherapy, the overall survival of patients with grade 4 glioblastoma (GBM) remains extremely poor (average survival time <2 years). Altered lipid metabolism, which increases fatty acid synthesis and thereby contributes to radioresistance in GBM, is a hallmark of cancer. …”
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Levels and related factors of occupational stress among nurses: hospital-based evidence from China, 2023 by Xiaoying Zhong, Yan Zeng, Lin Peng, Xixi Li, Yuanli Jia, Changqing Pan, Bangjun Wang

“…A p-value of less than 0.05 was considered statistically significant.ResultsThe participants’ average scores for the NJSS and Family APGAR Index were 1.76 ± 0.58 and 6.35 ± 3.30 points, respectively. …”
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Growth and survival of giant gourami juvenile immersed in different doses of recombinant growth hormone by , Alimuddin, Sumie Etoh, Handika Gilang Pramana Putra, Odang Carman

“…The results showed that the average body weight of 30 mg/L r-OgGH treated fish (0.34 g) was 75% higher (p<0.05) than those of 10 mg/L (0.24 g) and control (0.19 g). …”
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EFFECT OF DIFFERENT SEED PRIMING METHODS ON PERFORMANCE OF DIRECT BROADCAST SEEDED RICE (DBSR) IN CHITWAN, NEPAL by Raj Narayan Chaudhary, Surya Bahadur Thapa

“…The research results showed that priming resulted uniform plant population, faster crop establishment and better crop productivity. The average of 3660 kg ha-1 grain yield was obtained due to priming in this experiment. …”
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Cochlear implantation outcomes in adults: A scoping review. by Isabelle Boisvert, Mariana Reis, Agnes Au, Robert Cowan, Richard C Dowell

“…Data synthesis conducted with the 102 articles with more than 10 participants highlighted that the average word perception ability improved from 8.2% to 53.9% after implantation. …”
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Shaping Treatment Expectation to Optimize Efficacy of Interleukin 17A Antagonist Secukinumab in Psoriasis Patients by Hölsken S, Krefting F, Mühlhaus S, Bese D, Schedlowski M, Sondermann W

“…We evaluated skin symptoms using the Psoriasis Area and Severity Index (PASI), the Dermatology Life Quality Index (DLQI), perceived itch, mood and plasma IL-17A levels at baseline and at 1, 2, 3, 4, 8, 12, and 16 weeks post intervention.Results: The study included N = 120 patients (average age = 45.78 years, 34% female). A high baseline expectation level (8.1 of 10 points) was observed across all groups which could not be further increased by the EXP-group’s “cover story”. …”
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A first study on sperm sexing in water buffalo through magnetic nanoparticles by Syed Murtaza Hassan Andrabi, Muhammad Hammad Fayyaz, Muhammad Shafiq Haider, Ghulam Muhammad Ali

“…The mean fold expression of the PLP gene (X chromosome bearing sperm) was higher (p<0.05) in all sexed groups (average: 15.34-fold = 91.09% X chromosome bearing sperm) as compared to control (1.60- fold). …”
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Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial by Jiawei Shang, Ziming Yuan, Zuoyan Zhang, Quanhong Zhou, Yan Zou, Wei Wang

“…The corresponding hazard ratio of the primary outcome in the intermittently scanned CGM (isCGM) group when compared with the point-of-care testing (POCT) group was 0.18 (95% CI 0.04-0.79). The average length of ICU stay was 10.0 (SD 7.57) days in the isCGM group and 14.0 (SD 6.86) days in the POCT group (P=.02). …”
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Anemia Prevalence and Risk Factors in Two of Ethiopia’s Most Anemic Regions among Women: A Cross-Sectional Study by Gebru Gebremeskel Gebrerufael, Bsrat Tesfay Hagos

“…Therefore, to lessen the prevalence of anemia in certain parts of Ethiopia, public health initiatives that improve maternal health service utilization are required, such as ANC follow-up to minimize parity.…”
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Pour une théorie de la réception du discours grammatical by Jean-Rémi Lapaire

“…Their answers provide valuable insight into cognitive processing and the formation of grammatical concepts in the average learner’s mind, while revealing some important dimensions of metalinguistic knowledge: the degree of metalinguistic confidence in one’s ability to construe grammatical phenomena, the metalinguistic transparency, distance and persuasive force of a particular label, concept or description; metalinguistic avoidance strategies, centrality and salience (in metalinguistic categorization). …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…Prevalence measures of sociological interest, provided by analysing their traces on banknote dust, are less affected by the variability of their concentrations in each bill because banknote dust represents an averaged sample of high statistical significance. Methods: A simple banknote dust (10.0 ± 0.1 mg) extraction made use of 10 ml of a green extractant, comprising 98 % water, 2 % ethanol, and 0.1 % formic acid. …”
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Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting Neisseria gonorrhoeae in urine specimens by Lao-Tzu Allan-Blitz, Gordon Adams, Gabriela Sanders, Palak Shah, Krithik Ramesh, Jana Jarolimova, Kevin L. Ard, John A. Branda, Jeffrey D. Klausner, Pardis C. Sabeti, Jacob E. Lemieux

“…Extraction with 0.02% Triton X resulted in an average DNA yield of 2.6 × 106 copies/µL (SD ± 6.7 × 105). …”
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Perancangan Antarmuka dan Pengalaman Pengguna pada Prototipe Aplikasi Operasional Notaris menggunakan Metode Ethnographic Field Studies dan User Centered Design by Aqila Fayyadh Ferliamo, Buce Trias Hanggara, Yusi Tyroni Mursityo

“…To test the suitability of the design with the needs of stakeholders, usability testing was carried out on 5 different notaries using success rate metrics with an average rate of 97.2% and system usability scale questionnaire resulting in a score of 93 out of a maximum of 100, grade A, and an adjective rating of Excellent category. …”
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Micro-nano aerated subsurface drip irrigation and biochar promote photosynthesis, dry matter accumulation and yield of cucumbers in greenhouse by Zan Ouyang, Jie Zhang, Xueli Liang, Hui Wang, Zhenfeng Yang, Rong Tang, Qihua Yu, Yong Zhang

“…Compared to CK, in the two-season experiment, the average soil aeration porosity (SAP) increased by 0.53–44.00 %, the soil oxygen content (SO) increased by 0.47–31.80 %, the net photosynthetic rate (Pn) increased by 1.91–50.78 %, the dry matter accumulation increased by 10.53–69.19 %, the yield increased by 1.72–44.23 %, and the water use efficiency (WUE) improved by 0.42–76.57 %. …”
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Factors associated with thermal injury of abdominal skin in focused ultrasound ablation of uterine fibroids by Tang Chendian, Huang Guohua, Zhibiao Wang, Liu Fang, Shuang Luo, Xiaofang Liu, Qiuling Shi

“…In addition, the factors influencing the degree of thermal injury were analyzed using Kruskal–Wallis H.Results (1) Abdominal scars (p = .007, OR = 2.187, 95% CI: 1.242–3.849), abdominal wall thickness (p < .001, OR = 1.042, 95% CI: 1.019–1.067), fundus fibroids (p = .038, OR = 1.790, 95% CI: 1.033–3.100), UFs with hyperintense/mixed T2-weighted imaging (T2WI) signals (p = .022, OR = 1.843, 95% CI: 1.091–3.115), average sonication power (AP) (p = .025, OR = 1.021, 95% CI: 1.003–1.039), and treatment time (TT) (p < .001, OR = 1.017, 95% CI: 1.011–1.023) were independent risk factors for thermal injury, while treatment volume (TV) (p = .002, OR = 0.775, 95% CI: 0.661–0.909) was a protective factor for injury. (2) Four groups were subdivided according to the degree of thermal injury(Group A: without skin injury. …”
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Quality Assessment of Systematic Review of the Bariatric Surgery for Diabetes Mellitus by Xinye Jin, Jinjing Wang, Xueqiong Li, Ping An, Haibin Wang, Wenfeng Mao, Qi Zhou, Yaolong Chen, Jie Wang, Kang Chen, Yiming Mu

“…A total of 64 SRs were included. The average AMSTAR score was 7.4±1.7. AMSTAR scores of 7 (n=21, 32.8%) and 8 (n=14, 28.1%) were most common. …”
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Militancia, destrucción y resistencias de las mujeres en la Unión Patriótica by Carlos Andrés Torres Mateus

“…Éste el producto de una investigación histórica que abarcó temporalmente 26 años ubicándose entre 1984 y 2010, y se propone identificar el papel de éstas en la consolidación regional de la Unión Patriótica, demostrando su rol determinante en la expansión del movimiento político. De esta manera, examina los escenarios de representación y acción política de las mujeres y cómo estos representaron una amenaza para el bloque de poder. …”
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Optimum technique of carotid artery reconstruction in her atherosclerotic lesion by V. V. Akhmetov, V. I. Dunaeva, F. A. Vryganov, S. V. Ordynets, I. P. Dudano

“…There were 848 men and 394 women, the average age was 63.16 years, all of them were sympto- matic. …”
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