Economic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result by Michael J. Morris, Sheila A. Habib, Maggie L. Do Valle, John E. Schneider

“… # Objectives This study evaluated the potential cost savings for US payers of CyPath® Lung, a novel diagnostic tool utilizing flow cytometry and machine learning for the early detection of lung cancer, in patients with positive LDCT scans with indeterminate pulmonary nodules (IPNs) ranging from 6 to 29 mm…”
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The Effect of Predicted Compliance With a Web-Based Intervention for Anxiety and Depression Among Latin American University Students: Randomized Controlled Trial by Corina Benjet, Nur Hani Zainal, Yesica Albor, Libia Alvis-Barranco, Nayib Carrasco Tapia, Carlos C Contreras-Ibáñez, Jacqueline Cortés-Morelos, Lorena Cudris-Torres, Francisco R de la Peña, Noé González, Raúl A Gutierrez-Garcia, Eunice Vargas-Contreras, Maria Elena Medina-Mora, Pamela Patiño, Sarah M Gildea, Chris J Kennedy, Alex Luedtke, Nancy A Sampson, Maria V Petukhova, Jose R Zubizarreta, Pim Cuijpers, Alan E Kazdin, Ronald C Kessler

“…Subgroup analysis showed that this longer-term superiority of self-guided wb-CBT was confined to the 40% (528/1319) of participants with high predicted self-guided wb-CBT compliance beyond 3 months based on a counterfactual nested cross-validated machine learning model. The 12-month outcome differences were nonsignificant across arms among other participants (all P>.05). …”
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Assessing the Impact of Traffic Emissions on Fine Particulate Matter and Carbon Monoxide Levels in Hanoi through COVID-19 Social Distancing Periods by Nhung H. Le, Bich-Thuy Ly, Phong K. Thai, Gia-Huy Pham, Ich-Hung Ngo, Van-Nguyet Do, Thuy T. Le, Luan V. Nhu, Ha Dang Son, Yen-Lien T. Nguyen, Duong H. Pham, Tuan V. Vu

“…To overcome this challenge, weather normalized concentrations of those pollutants were estimated using the random forest model, a machine learning technique. The normalized weather concentrations showed smaller reductions by 7–10% for PM2.5 and 5–11% for CO, indicating the presence of favorable weather conditions for better air quality during the social distancing period. …”
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Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: A cohort study. by Andrew F Auld, Andrew D Kerkhoff, Yasmeen Hanifa, Robin Wood, Salome Charalambous, Yuliang Liu, Tefera Agizew, Anikie Mathoma, Rosanna Boyd, Anand Date, Ray W Shiraishi, George Bicego, Unami Mathebula-Modongo, Heather Alexander, Christopher Serumola, Goabaone Rankgoane-Pono, Pontsho Pono, Alyssa Finlay, James C Shepherd, Tedd V Ellerbrock, Alison D Grant, Katherine Fielding

“…<h4>Methods and findings</h4>We used Botswana XPRES trial data for adult HIV clinic enrollees collected during 2012 to 2015 to develop a parsimonious multivariable prognostic model for active prevalent TB using both logistic regression and random forest machine learning approaches. …”
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