Constitutional Handcuffs by Richard Albert

“…Third, in concluding that absolute entrenchment undermines the participatory values that give constitutionalism its meaning, it proposes an alternative to entrenchment: the entrenchment simulator. …”
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SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation by Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Xia Zhao, Louis Y. El Khoury, Shafiq Shaikh, Jian Zhong, Jeong-Heon Lee, Jolanta Grembecka, Tomasz Cierpicki, Thai H. Ho, Keith D. Robertson

“…Abstract Background SETD2 is the sole epigenetic factor responsible for catalyzing histone 3, lysine 36, tri-methylation (H3K36me3) in mammals. Its role in regulating cellular processes such as RNA splicing, DNA repair, and spurious transcription initiation underlies its broader tumor suppressor function. …”
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An Investigation of Presumptive Synergism of Oil Palm Bunch Ash and Sawdust Amendments in Remediation of crude oil Spiked Soil by Ejikeme Albert, Di Anyanwu

“…Two kilogram (2 kg) of sandy soil was placed in each of five plastic vessels labeled TA, TB, TC, TD and TE. TA was left in its natural state while the others were each polluted with 6.7% v/w of crude oil. …”
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Stability and Convergence of Nuclear Detonations in White Dwarf Collisions by Peter Anninos, David Cruz-Lopez, Brighten Jiang, Emanuel Gordis

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Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“…Participants diagnosed with depression and either type 2 diabetes or low back pain (n=183) were randomized to “intervention + iTAU” (combining a face-to-face intervention with a supporting web-based program) or “iTAU” alone. …”
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ADAPTING TO A CHANGING WORLD: STRATEGIES FOR MITIGATING THE GLOBAL CONSEQUENCES OF CLIMATE CHANGE by FRANK FUNKEYE SAPELE, AKUMKA JOSEPH YABAYANZE, KANYINSOLA AZEEZ

“…This research structures its opinions with the human security model as its theoretical framework. …”
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Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae. by Ankit Kumar, Farah Anjum, Md Imtaiyaz Hassan, Anas Shamsi, Rashmi Prabha Singh

“…The bacterium possesses a thick polysaccharide capsule and fimbriae, which contribute to its virulence, resistance to phagocytosis, and attachment to host cells. …”
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Modeling Factors Influencing Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…ObjectiveProject financing has emerged as a critical mechanism for funding infrastructure and capital-intensive projects across various sectors, both in the public and private domains. Its significance has grown notably in recent decades within the financial market, reflecting its pivotal role in facilitating economic development. …”
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Adaptive backstepping control for electro-hydraulic servo system in extension sleeve press-fitting process of bearing pressing machine by Chen Hongsheng

“…In the process of extension sleeve press-fitting of the bearing pressing machine, electro-hydraulic servo system of valve-controlled symmetrical cylinder (ESSVSC) is an important and critical control module, and its performance has a significant impact on the working accuracy of such equipment. …”
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Chemical reaction and Soret impacts on MHD heat and mass transfer Casson hybrid nanofluid (MoS2+ZnO) flow based on engine oil across a stretching sheet with radiation by M. Radhika, Y. Dharmendar Reddy

“…By investigating the hybrid nanofluid's wear resistance, viscosity, and thermal conductivity, the current study fills this knowledge gap and illuminates its potential as a cutting-edge lubricant. The primary objective of investigating the hybrid nano lubricant MoS2 + ZnO combined with engine oil is to further the development of more durable and efficient lubrication solutions for automotive engines, hence improving reliability, fuel efficiency, and environmental sustainability. …”
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Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration by Hamid Riazi-Esfahani, Hooshang Faghihi, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hassan Khojasteh, Ahmed Husein Ahmed, Shahin Faghihi, Ali Fakhraie, Mohammad Hossein Zamani, Samin Ghasemi, Esmaeil Asadi Khameneh, Elias Khalili Pour

“…The largest PED width correlated significantly with lower BCVA gains at months 3 (P = 0.021) and 12 (P = 0.043), suggesting its potential as a prognostic factor. Conclusion Baseline OCT biomarkers, including SIPED, IRF, and PED width, may predict visual acuity changes in nAMD patients treated with aflibercept, highlighting the need for individualized monitoring. …”
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How Ethanol Is Made from Cellulosic Biomass by Zhaohui Tong, Pratap Pullammanappallil, Arthur A. Teixeira

“…This 4-page fact sheet provides a general overview of the production process for manufacturing ethanol from cellulosic biomass, including its constituents, conversion processes, and final products. …”
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The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Connor J Plaisance, Lloyd F Ledet III, Nicholas J Slusher, Charles P Daniel, Zachary Lee, Bradley Dorius, Sonnah Barrie, Tomasina Q Parker-Actlis, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

“…The focus of the present investigation is to delve into the current literature regarding dopamine and its clinical implications in substance use disorder and impulsive behavior.…”
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Oxidative stress and antioxidant status among the elderly in Jakarta by Novi Silvia Hardiany, Daniya Qanita Amani, Jasmine Virginia Anjani, Prima Christin Natalia, Rheina Tamara Tarigan

“…Oxidative stress is a key contributor to the development of degenerative diseases associated with aging, while antioxidant defenses can mitigate its effects. Objective: This study aimed to assess oxidative stress levels, measured by malondialdehyde (MDA), and antioxidant status, including catalase, reduced glutathione (GSH), and vitamin C, in the elderly population of Jakarta. …”
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Klasifikasi Pola Pergerakan Bola Mata Menggunakan Metode Multilayer Backpropagation by Karina Amadea, Fitra A. Bachtiar, Gusti Pangestu

“…Sedangkan untuk parameter-parameter yang digunakan yaitu learning rate sebesar 0,7 dan iterasi sebanyak 100 iterasi. Hasil dari klasifikasi pola pergerakan mata memperoleh tingkat akurasi sebesar 88,24% pada saat pelatihan dan 80,95% pada saat pengujian.   …”
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Association of per- and polyfluoroalkyl substances with gout risk: a cross-sectional analysis of NHANES 2007–2018 data emphasizing mixture effects by Haixin Feng, Siran Li, Shiqing Huang, Linxi He, Ruihao Huang, Renhuizi Wei, Xin Peng, Haiyi Yan, Chongxiang Xiong, Bingsong Zhang

“…PFOA is highly persistent in the body, mainly accumulating in the kidneys and liver through enterohepatic circulation, posing risks due to its difficulty in metabolism and excretion. PFHxS has the longest metabolic half-life in humans (7.3 years) and bioaccumulates in the endocrine, immune, nervous, and reproductive systems. …”
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Attachment Styles, Personality, and Frustration Intolerance by Christian Schetsche, Alba E. Mustaca

“…Avoidant attachment stood out for its mediating effect on anxious attachment. These two factors were found to explain a considerable percentage of neuroticism and, as a consequence, the four dimensions of FI. …”
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FROM ONCOLOGIST TO SURGEON - GENETICS IN COLORECTAL METASTASIS FOR SURGEONS by Marília Polo Mingueti e SILVA, Jorge SABBAGA, Henry Luiz NAJMAN, Carlos David Carvalho NASCIMENTO, Ricardo Lemos COTTA-PEREIRA, João Eduardo Leal NICOLUZZI, Maria Ignez BRAGHIROLI

“…Sporadic disease is characterized by the absence of a family history and accounts for approximately 70% of all colorectal cancers, being more common over 50 years of age, with dietary and environmental factors implicated in its pathogenesis. Sporadic disease is characterized by the absence of a family history and accounts for approximately 70% of all colorectal cancers, being more common over 50 years of age, with dietary and environmental factors implicated in its pathogenesis. …”
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Simultaneous cardiocerebral infarctions: a five-year retrospective case series reviewing natural history by Cheryl Zhiya Chong, Benjamin Yong-Qiang Tan, Ching-Hui Sia, Thet Khaing, Leonard Leong Litt Yeo

“…In this series, IV tPA at stroke doses appeared to be the preferred initial step for its treatment, with subsequent coronary or cerebral endovascular therapy, if necessary.…”
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Crop Diversification for Ensuring Sustainable Agriculture, Risk Management and Food Security by Tesfahun Belay Mihrete, Fasikaw Belay Mihretu

“…This review examines crop diversification as a response to these challenges, with a focus on its applications in sustainable agriculture, risk management, and food security. …”
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