CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT... by Yongbo Zhang, Sheng Yang, Xuan You, Zhengguang Li, Liuyang chen, Rui Dai, Hua Sun, Liang Zhang

“…CircSPG21 also ameliorated disc degeneration in the IVDD rat model, highlighting its potential as a therapeutic target. Conclusion CircSPG21 reduces oxidative stress-induced NPMSC senescence through the miR-217/SIRT1 axis and mitophagy, providing new insights into IVDD and identifying circSPG21 as a potential therapeutic target for disc degeneration.…”
Get full text

Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure by Robert R. Brown, Robert R. Brown, Robert R. Brown, Barbara Biebrich

“…This revolutionary in vivo method to assess radiofrequency radiation induced rouleaux formation should be further pursued in the general population to determine its prevalence and if its occurrence provides a unique biomarker of exposure that may predict morbidity.…”
Get full text

RESEARCH ON SINGLE-LEAF WALLS MADE WITH LIGHTENED CLAY BRICKS by MANUEL C. JUÁREZ, Mª PILAR MORALES, PEDRO MUÑOZ, PABLO OLASOLO

“…A first aspect is to study the possibility of lightening the clay by using additives, reducing the clay’s conductivity without decreasing its resistive ability. The internal and external geometry of the bricks has been studied by the Finite Element Method (FEM). …”
Get full text

Segmentasi Pelanggan B2B Berdasarkan Perilaku Pembelian dan Firmografi pada PT. Sukses Riau Permata (SRP) by Siti monalisa, Novia Nurahmah

“…SRP belum mengidentifikasi pelanggan mana yang berkontribusi dan mana yang tidak memberikan keuntungan pada perusahaan akibatnya program pemasaran masih diberlakukan seragam kepada semua pelanggan. Maka dari itu pada penelitian ini dilakukan pengelompokan pelanggan berdasar kepada perilaku pembelian dan firmografi dengan algoritma Fuzzy C-Means. …”
Get full text

Case study of a neuroendocrine tumor of uncertain origin: single-cell transcriptomics unravels potential primary location by Frolova Tatyana, Ekaterina Avsievich, Diana Salimgereeva, Zoia Antysheva, Alesia Maluchenko, Denis Maksimov, Ilia Feidorov, Mark Voloshin, Olga Glazova, Natalia Bodunova, Nikolay Karnaukhov, Pavel Volchkov, Julia Krupinova

“…This study explores the histogenesis of a retroperitoneal, non-functional NET localized between the duodenum and pancreatic head, utilizing advanced molecular diagnostics to elucidate its probable primary source. Methods Initial diagnostic methods, including imaging and histopathology, failed to resolve the tumor’s origin. …”
Get full text

The illusion of limitlessness: Engaging Cornel du Toit’s perspective on transhumanism and being by Benson O. Igboin

“…This article analysed Du Toit’s arguments and concedes with him that religion has its place even in a supposedly ultra-techno-deterministic world. …”
Get full text

Pemilihan Susu Formula Anak Menggunakan Metode Analytic Hierarchy Process dan Simple Additive Weighting by Heribertus Ary Setyadi, Ahmad Fauzi, Galih S Nurohim, Doddy Satrya Perbawa

“…In this research, alternatives of milk brands can be added, changed and deleted so it’s dynamic. Criterias in this research are divided into more detailed sub-criteria. …”
Get full text

A False Spider Mite, Brevipalpus californicus (Banks) (Archnida: Acari: Tenuipalpidae) by Harold A. Denmark

“…It describes this mite pest with an extensive host range, its synonymy, distribution, description, hosts, economic importance, management, survey and detection, management, and selected references. …”
Get full text

Clinical and Morphological Features of Dysplasia and Early Gastric Cancer in the Patients with Autoimmune Gastritis by A. S. Tertychnyy, N. V. Pachuashvili, D. P. Nagornaya, T. L. Lapina, E. A. Losik, A. B. Ponomarev, P. V. Pavlov, A. P. Kiryukhin, A. A. Fedorenko, D. D. Protsenko, V. T. Ivashkin

“…The presented cases of tumours were not accompanied by hyperplasia of neuroendocrine cells directly in the area of the tumour itself, but only in the surrounding gastric mucosa. …”
Get full text

Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis by D. V. Garbuzenko

“…Antiangiogenic therapy, selectively directed at unusually growing newly-formed vessels, can be a pathogenetically justified method for treating portal hypertension in liver cirrhosis on its subclinical stage.…”
Get full text

One Mean Weed! by Charles Jacoby, Nanette Holland, Debbi Berger

“…This 6-page activity illustrates how characteristics of the autumn olive, Elaeagnus umbellata, influence its ability to invade habitats. …”
Get full text

Knowledge Attitude and Practices of Mothers on Management of Malnutrition Among Children Under Five Years in Bugongi Town Council, Sheema District. by Mwiine, Dickens Richard

“…However, the prevalence of stunting in Sheema has remained high despite its agricultural potential and significant agricultural exports. …”
Get full text

Level of Pollution of Water from River Rwabakazi Indicated by Metal Ions and Suspended Solids Concentrations. by Habimana, Michael

“…Pollution resulting from increased anthropogenic activities is affecting river Rwabakazi. Its effects are reflected by high concentrations of calcium, iron (II). iron ( 111), magnesium and total suspended solids (TSS). …”
Get full text

Lending appraisal and performance of SACCOS in Rukiga district, Uganda by Moses, Agaba, John Bosco, turyasingura, Jesse David, Kabagambe

“…Since descriptive analysis entailed description of a single variable and its attributes, frequency tables were used to present the data. …”
Get full text

Modelling and Simulation of The Spread of HBV Disease. by Niyirora, Ignatius

“…Also we give a bifurcation diagram of the infected population against the vaccination rate which shows that when Ro :S I the values of the infected population I@) tends to its disease free equilibrium values. This model shows that when the vaccination fails to force the basic reproduction number to be less than one in value the disease fires up and approaches an endemic level. …”
Get full text

Lycopene improves on basic hematological and immunological parameters in diabetes mellitus by Ejike, Daniel Eze, Adam, Moyosore Afodun, Josephine, Kasolo, Keneth Iceland, Kasozi

“…There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables.…”
Get full text

Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmium- challenged rats by Ejike, Daniel Eze, Okpa, Precious Nwaka, Igbokwe, Ugochukwu Vincent, Moses, Dele Adams, Karimah, Mohammed Rabiu, Ayikobua, Emmanuel Tiyo

“…However, Carpolobia lutea and its co-administration notably (p<0.05) elevated the activity of testicular 17β-HSD and levels of serum testosterone, LH and FSH. …”
Get full text

High-Prevalence Stunting in Preschool Children (1–5 Years) Attending Selected Health Centers in a Food Rich Area-Bushenyi District Southwestern Uganda by Douglas, Mugarura, Herbert Izo, Ninsiima, Hellen, Kinyi, Ejike, Daniel Eze, Sam, Tumwesigire, Andrew, Ndamira

“…+is was a cross-sectional study assessing the prevalence of stunting and its associated factors among children aged 1–5 years attending selected health centers in Bushenyi District. …”
Get full text

Assessment of Record Keeping Practices in Nursing Schools: A Case of Uganda Nursing School-Bwindi. by Gambamazima, Ruth

“…The results indicated that; the department has never appraised or disposed its records ever since its establishment, records had already filled up the strong room which is no longer accessible and some of the records are staffed in boxes and some piled on the floors. …”
Get full text

The Impact of Stone Quarrying on Socio Economic Status of Households in Nyakyibigi Ntungamo Municipality. by Natweeta, Elvason

“…The study recommended there should be strengthening of security in quarrying areas in order to protect the quarrying activities which leads to improvement at the quarrying site, there should be carefully pre-planning of the project to ensure that the quarrying process takes place well and in its actual state because when this one is done, then the activity also goes on well to facilitate the desires of the community and there should be fitting of drills with dust collection systems and purchasing additional land surrounding the mine to act as a buffer zone and trees planted in these buffer zones can also minimize the visual impact of quarrying operations on local communities.…”
Get full text