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7001
SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate
Published 2024-12-01“…From a developability standpoint, SPA14 could be manufactured by a simple and scalable ethanol injection method, owing to the high solubility in ethanol of all its lipidic components, including E6020. Furthermore, E6020 is a single molecule, well-characterized fully synthetic TLR4 agonist constructed in eight synthetic steps from entirely crystalline starting materials and intermediates via an optimized high-yield synthetic route. …”
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7002
Pengembangan Aplikasi Pemantauan Jaringan Berbasis Web pada Software-Defined Networking dengan Protokol SFLOW
Published 2021-11-01“…SDN controller seperti ONOS hanya berfungsi untuk manajemen flow table dan tidak memiliki fitur pemantauan traffic jaringan yang cukup untuk mendukung proses manajemen jaringan. Oleh karena itu, untuk melakukan pemantauan traffic SDN maka diperlukan protokol lain seperti sFlow. …”
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7003
Nurture-U student mental health longitudinal survey: a study protocol
Published 2025-02-01“…Recent trends indicate rising mental health concerns among university students, exacerbated by the COVID-19 pandemic and its aftermath. This study aims to address gaps in longitudinal data on student mental health in the UK and to identify risk and protective factors across diverse student populations.Methods and analysis The current Nurture-U survey is developed from the U-Flourish biannual survey study piloted at Queen’s and Oxford universities in Canada and the UK, respectively. …”
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7004
Evaluation of the Marginal Fit of Full Contoured Zirconia, Lithium Disilicate and Metal Crowns Fabricated Using CAD-CAM: An in Vitro Study
Published 2023-04-01“…Introduction: The marginal fit of any dental restoration is vital to its long-term success. Lack of adequate fit is potentially detrimental to both the tooth and the supporting periodontal tissues. …”
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7005
儿童肝糖原贮积病血糖及生化指标的横断面调查
Published 2025-01-01“…65.9%(29/44)的家庭受检者的血糖 ≤ 3.9 mmol/L,与肝GSD组比较,低血糖的患病率差异无统计学意义(<italic>P </italic>=0.658)。生化检测中,肝GSD患者高乳酸血症、高尿酸血症和高胆固醇血症的患病率分别为65.9%、45.5%和9.1%,而家庭对照受检者分别为18.2%,43.2%,15.9%,两组的高尿酸血症和高胆固醇血症患病率差异无统计学意义(<italic>P</italic>=0.830, <italic>P</italic>=0.334)。…”
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7006
THE ROLE OF THE MULTINATIONAL JOINT TASK FORCE IN COUNTER INSURGENCY IN NORTH EASTERN NIGERIA: THE BOKO- HARAMINSURGENCY
Published 2024-08-01“…The study recommends that good moral, values, religious education will serve as panaceas in controlling and bringing to an end religious insurgencies in the north eastern Nigeria and its environs. …”
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7007
3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3
Published 2025-01-01“…While the toxicological effects of 3-ADON on human and animal health are well-documented, its specific impact on the reproductive system remains underexplored. …”
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7008
Rodzice o dobrej publicznej szkole dla swoich dzieci. Fenomenograficzna ilustracja
Published 2021-09-01“…However, not by following legislation demonstrating its public status, but by means of a simple question addressed to the parents of pupils in grades I to III as to how this phenomenon is understood by them. …”
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7009
Simulation study for the energy and position reconstruction performances of the beam monitoring system of Carbon Ion Radiation Therapy using GEANT4.
Published 2025-01-01“…Carbon Ion Radiation Therapy is operated in several countries because of its advantage to have high dose concentration and/or high linear energy transfer (LET). …”
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7010
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7011
НАВЧАЛЬНЕ ПРОГРАМУВАННЯ В КОНТЕКСТІ РЕФЛЕКСІЇ РОЗУМОВИХ ДІЙ ТА ЇХ ФОРМАЛІЗАЦІЯ ПРОГРАМНИМ КОДОМ
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7012
Style adaptacji uczniów do szkoły. Inspiracje dla nauczycieli wczesnej edukacji
Published 2019-12-01“…The paper presents the issue of students adaptation to school life and shows its importance for the practice of early education teachers. …”
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7013
Detection of AdeAB, TetA, and TetB efflux pump genes in clinical isolates of tetracycline-resistant Acinetobacter baumannii from patients of Suez Canal University Hospitals
Published 2025-02-01“…Abstract Background Acinetobacter baumannii is an opportunistic bacteria associated primarily with hospital-acquired infections. Its tendency to acquire or donate resistance genes to neighboring bacteria is a major concern. …”
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7014
Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes
Published 2025-02-01“…The survey consists of 342 items across 5 domains: comorbidities (96), health behaviours (80), QoL (41), unmet needs (75) and mental health (50). …”
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7015
Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study
Published 2014-07-01“…Analysis has been carried out for intention to treat (ITT) populations with application of 16-th week AVT data.Results. …”
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7016
The impact of PD-L1 expression status on the prognosis of ALK-positive lung cancer patients
Published 2024-01-01“…PD-L1 serves as an independent predictor of adverse outcomes, indicating its potential as a biomarker for assessing lung cancer severity and prognosis.…”
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7017
Evolution, Characteristics and Inspirations of Management Zoning for National Parks in the United States
Published 2025-02-01“…In addition, this research analyzes the nine characteristics of the management zoning for national parks in the United States: 1) Functional attribute of zoning — transform from functional zoning to comprehensive control zoning; 2) functional characteristics of zoning — most zones are similar to China’s main functional zone, rather than the restricted red line zone; 3) functional goal of zoning — strive to achieve the dual balance of “protection − utilization”; 4) zoning policies are of flexibility and complete; 5) zoning is based on the dynamic adaptive management theory; 6) zoning should be supported by a more comprehensive and systematic policy system; 7) zoning must be based on a scientific and rigorous policy system; 8) different designation areas and autonomous zoning composed its rigid and flexible frame; 9) zoning may be deduced through the comparison of multiple scenaro.ConclusionChina’s national park zoning should be regarded as a technical method relying on management rules, for which the system development should be strengthened. …”
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7018
Analisis Tren dan Perkiraan Pandemi COVID-19 di Indonesia Menggunakan Peramalan Metode Prophet :Sebelum dan Sesudah Aturan New Normal
Published 2022-02-01“…Dalam menanggulangi penyebaran pandemi Covid-19 di Indonesia, pemerintah telah menetapkan PSBB dan aturan Normal Baru namun laju penyebaran pandemi terus meningkat dari waktu ke waktu. Selain itu, ketidakpastian akan berakhirnya pandemi ini berdampak pada perubahan kondisi sosial. …”
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7019
Shift in the profile and prognostic implications in invasive fungal rhinosinusitis: experience of 10 years in a tertiary center
Published 2025-02-01“…Evidence on how to optimize its management is still limited. We present a case series from our institution aiming to fill the knowledge gap. …”
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7020