Biomarkers of gastric atrophy at stomach cancer by A. V. Belkovets, S. A. Kurilovich., Yu. I. Ragino, L. V. Scherbakova, O. B. Cheremisina, N. V. Cherdyntseva, N. A. Andryushina, M. I. Voyevoda

“…To evaluate the markers of stomach atrophy along with risk factors of SC of different localization, histological type and stage in the «case series» study. …”
Get full text

The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…Following subcutaneous injection of antagomiRNA-211 (chemical modification inhibitor), the expression levels of the <i>AP1S2</i> gene and protein were enhanced, and the localization in the hair follicle was also increased. …”
Get full text

Epidemiologic, Clinical, Ultrasonographic, and Cytological Features of Thyroid Nodules in Predicting Malignancy Risk: A Retrospective Study of 442 French Afro-Caribbean Patients by Johan Joseph-Auguste, Lucien Lin, Magalie Demar, Olivier Duffas, Vincent Molinie, Caroline Sulpicy, Marie-Josée Dorival, Olivier Luxembourger, Nadia Sabbah

“…There was no significant difference in age, nodule localization, number of nodules, or thyroid function test between benign and malignant nodules. …”
Get full text

Peculiar morphology of Asgard archaeal cells close to the prokaryote-eukaryote boundary by Burak Avcı, Kassiani Panagiotou, Mads Albertsen, Thijs J. G. Ettema, Andreas Schramm, Kasper Urup Kjeldsen

“…Hodarchaeales-affiliated cells were characterized by an elongated cell body connected to a rounded expansion at one pole with a confined central DNA localization. They were conspicuously large, with an average length of 3 µm, ranging from 1.5 to 5.2 µm. …”
Get full text

High Expression of VSTM2L Induced Resistance to Chemoradiotherapy in Rectal Cancer through Downstream IL-4 Signaling by Hao Liu, Zhenzhan Zhang, Peilin Zhen, Meijuan Zhou

“…Preoperative chemoradiotherapy (pCRT) is a common and essential therapeutic strategy for patients with locally advanced rectal cancer (LARC), but poor tumor response and therapeutic resistance to chemoradiotherapy have appeared usually among persons and affected those patients’ survival prognosis. …”
Get full text

TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…TWIST1 was found to directly bind and interact with HK2, showing co-localization in the cytoplasm of PDAC cells. Furthermore, TWIST1 was shown to stabilize HK2 by inhibiting its ubiquitin-mediated degradation. …”
Get full text

Genome-Wide Identification of <i>MsICE</i> Gene Family in <i>Medicago sativa</i> and Expression Analysis of the Response to Abiotic Stress by Baiji Wang, Qianning Liu, Wen Xu, Yuying Yuan, Muzhapaer Tuluhong, Jinqiu Yu, Guowen Cui

“…Through synteny analysis, we detected duplication events in the <i>MsICE</i> gene family, suggesting that the <i>ICE</i> gene family was formed through fragment duplications. …”
Get full text

Automatic Segmentation of the Infraorbital Canal in CBCT Images: Anatomical Structure Recognition Using Artificial Intelligence by Ismail Gumussoy, Emre Haylaz, Suayip Burak Duman, Fahrettin Kalabalık, Muhammet Can Eren, Seyda Say, Ozer Celik, Ibrahim Sevki Bayrakdar

“…The findings of this study demonstrated that the IOC can be detected with high precision and accuracy using an AI-based automatic segmentation method in CBCT images. …”
Get full text

Genome-Wide Analysis of the <i>NBS-LRR</i> Gene Family and SSR Molecular Markers Development in Solanaceae by Xiaoming Song, Chunjin Li, Zhuo Liu, Rong Zhou, Shaoqin Shen, Tong Yu, Li Jia, Nan Li

“…A total of 22,226 SSRs were detected from all genes of nine Solanaceae species. …”
Get full text

Anti-GluK2 Encephalitis in an Asian Child: A Case Report and Literature Review by Chen S, Kessi M, He F, Yin F, Peng J, Yang L

“…The anti-GluK2 antibodies and elevated IL-6 levels were detected in serum while high oligoclonal bands levels were found in the CSF. …”
Get full text

EGFR EXPRESSION IN RECTAL CANCER, RELATION TO THE FREAQUENCY OF LYMPH NODE METASTASIS by I. V. Stepanov, S. R. Altybaev, N. V. Krakhmal, К. V. Rachkovsky, D. A. Sorokin, S. G. Afanasyev, S. V. Vtorushin, М. V. Zavyalova

“…Thus, the expression and mutation of the EGFR gene is associated with various variants of tumor progression and an unfavorable prognosis for malignant tumors of various localizations. The purpose of the study was to investigate the EGFR expression in cancer tissue and evaluate the relationship between EGFR expression and parameters of lymphogenous metastasis in patients with rectal cancer.  …”
Get full text

The shared genetic landscape of polycystic ovary syndrome and breast cancer: convergence on ER + breast cancer but not ER- breast cancer by Kaixin Bi, Miaoran Chen, Qianru Zhao, Tongtong Yang, Wenjia Xie, Wenqi Ma, Hongyan Jia

“…After partitioning the genome into 2,495 independent regions, we identified two loci, chr8: 75,011,700–76,295,483 and chr17: 6,305,079–7,264,458, with significant localized genetic correlations. Pleiotropic analysis under a composite null hypothesis identified 1,183 significant pleiotropic single nucleotide polymorphisms (SNPs) across three trait pairs. …”
Get full text

Regulation of RHBDD1 in the invasion of esophageal cancer cells via ELK3/Wnt/β-catenin signaling pathway by Bing Xu, Hui Chen, Xinchen Sun, Hongyan Cheng, Kavimbi Chipusu, Wei Hua, Tingting Chen

“…Proliferation was assessed via CCK-8 (absorbance at 450 nm) and EdU assays (Ribo-Bio kit), while apoptosis was quantified by annexin V-FITC/PI staining using flow cytometry. Immunofluorescence detected β-catenin localization (Abcam antibodies). …”
Get full text

CRISPR‐Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide‐RNAs by Benjamín Durán‐Vinet, Jo‐Ann L. Stanton, Gert‐Jan Jeunen, Ulla vonAmmon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

“…Environmental DNA (eDNA) has transformed traditional biosurveillance by detecting trace DNA fragments left by organisms in their surroundings, primarily by applying quantitative polymerase chain reaction (qPCR) methods. …”
Get full text

VOLUMETRIC AND SPATIAL SEGMENTATION OF THE TIEN SHAN LITHOSPHERE ACCORDING TO GEOPHYSICAL DATA by A. K. Rybin, E. A. Bataleva, K. S. Nepeina, V. E. Matyukov

“…The sections are used to identify the zones with relatively low (i.e. reduced) seismic wave velocities and detect the deep-seated longitudinal segmentation of the folded belt. …”
Get full text

The features of PD-L1 expression in tumor stromal cells, peritumoral microvessels and isolated clusters of tumor cells in breast cancer tissue and their correlation with clinical a... by E. Yu. Zubareva, M. A. Senchukova, T. A. Karmakova, N. V. Zaitsev

“…Nuclear expression of PD-L1 was also detected in stromal cells, and was observed in 28.8 and 55.0 % of cases with nodular and diffuse forms of BC (p=0.003), in 17.6, 52.5 and 75.0 % of cases in early, locally advanced and metastatic BC (p&lt;0.001), in 21.2, 28.7, 80.0 and 55.0 % of cases in T1, T2, T3 and T4 (p=0.002), in 21.7, 35.3, 51.4 and 55.0 % of cases with N0, N1, N2 and N3 (p=0.005), in 49.0 and 29.0 % of cases with negative and positive status of PR (p=0.014), in 30.3 and 52.8 % of cases with HER2-negative and HER2-positive BC status (p=0.014), respectively.Conclusion. …”
Get full text

THE PREVALENCE OF SECONDARY DENTO-MAXILLAIRE DEFORMITIES ASSOCIATED WITH UNCOMPENSATED DENTITION DEFECTS IN CHILD POPULATION by S.I. Doroshenko, A.Ju. Zrazhevska, K.V. Storozhenko

“…Dentition defects of various sizes and localization were observed in 359 out of 2276 children, which is 15.8% of the total number of those examined. …”
Get full text

Climate change, armed conflict, forced displacement, and epidemic-prone diseases: an exploratory study in northern Syria by Maia C. Tarnas, Naser Almhawish, Ruwan Ratnayake, Yasir Elferruh, Ibrahim Aladhan, MHD Bahaa Aldin Alhaffar, Aula Abbara

“…Seasonal-trend decomposition with locally estimated scatterplot smoothing was also used to detect trends amidst seasonal fluctuations. …”
Get full text

The effect of <i>T. aestivum</i> chromosomes 1A and 1D on fertility of alloplasmic recombinant (<i>H. vulgare</i>)-<i>T. aestivum</i> lines depending on cytonuclear compatibility by L. A. Pershina, N. V. Trubacheeva, V. K. Shumny

“…Wheattype homoplasmy (hm) was detected in the majority of the fertile plants, which was associated with cytonuclear coadaptation. …”
Get full text

Synchronous Acquisition and Processing of Electro- and Phono-Cardiogram Signals for Accurate Systolic Times’ Measurement in Heart Disease Diagnosis and Monitoring by Roberto De Fazio, Ilaria Cascella, Şule Esma Yalçınkaya, Massimo De Vittorio, Luigi Patrono, Ramiro Velazquez, Paolo Visconti

“…While electrocardiography (ECG) is the standard technique for evaluating the heart’s electrical activity and detecting rhythm and conduction abnormalities, it alone is insufficient for identifying certain conditions, such as valvular disorders. …”
Get full text