Genome-wide association study for protein and color content in a tetraploid wheat collection by Ilaria Marcotuli, Patricia Cabas-Lühmann, Davide Caranfa, Antonia Mores, Stefania Lucia Giove, Pasqualina Colasuonno, Sara Muciaccia, Maria Simone, Andrés R. Schwember, Agata Gadaleta

“…QTL linked to GPC were detected on chromosomes 2 A, 3 A, 5 A, and 7 A, while QTL for YI were localized on chromosomes 1B, 2B, 3 A, 4B, 6 A, 6B, 7 A, reflecting their complex genetic nature. …”
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Novel Mycoplasma bovis membrane lipoproteins induce the inflammatory response of host epithelial cells and macrophage by Xiaotan Yuan, Xiaotan Yuan, Jiating Ma, Jiating Ma, Yiming Wu, Yiming Wu, Gang Zhao, Gang Zhao, Yujiong Wang, Yujiong Wang

“…Furthermore, polyclonal antibodies against the eight membrane lipoproteins were prepared and used to detect their subcellular localization.ResultsThe results revealed that MbovP0592 was a secreted lipoprotein, while MbovP0659, MbovP0536, MbovP0393 and MbovP0585 were confirmed as membrane lipoproteins. …”
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Protective role of extracellular vesicles against oxidative DNA damage by Jordi Ribas-Maynou, Ana Parra, Pablo Martínez-Díaz, Camila Peres Rubio, Xiomara Lucas, Marc Yeste, Jordi Roca, Isabel Barranco

“…In addition, our in vitro study opens path to detect, localize and quantify the protective effects against oxidation of extracellular vesicles derived from different fluids, elucidating their function in physiopathological states.…”
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Prevalence of gastroesophageal reflux disease, gastroduodenal erosions and ulcers and their association with the family predisposition to peptic ulcer disease in Siberian schoolchi... by T. V. Polivanova, E. V. Kasparov, V. A. Vshivkov, O. V. Peretyatko, T. N. Akhmetshin

“…We have examined schoolchildren aged 7–17 years in three regions of Siberia (Republic of Tyva, Evenkia and Buryatia) in localities identical to their socio-economic level. …”
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Functional ultrasound as a quantitative approach for measuring functional hyperemia in aging models by Jessica Pinckard, Sharon Negri, Cade A Huston, Marisa A Bickel, Michaela L Vance, Madison Milan, Clara L Hibbs, Madeline Budda, Siva Sai Chandragiri, Kaitlyn Pipkin, Stefano Tarantini, Shannon M Conley

“…Similarly, the ability of fUS ultrasound localization microscopy (ULM) to detect age-related vascular rarefaction was improved by the 14-day recovery time after window implantation. …”
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Spatial characterization of RPE structure and lipids in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder by Samy Omri, Catherine Argyriou, Rachel S. Pryce, Erminia Di Pietro, Pierre Chaurand, Nancy Braverman

“…We identified 47 lipid alterations preceding structural changes, 9 of which localize to the dorsal pole. 29 of these persist to 3 months, with remodeling of the dorsal pole lipid signature. 13 new alterations occur concurrent with histological changes. …”
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Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice by Meng Du, Xiaojing Wang, Xin Tan, Xiangrao Li, Dandan Huang, Kun Huang, Liu Yang, Fengxiao Zhang, Yan Wang, Dan Huang, Kai Huang

“…These mice demonstrated advanced atherosclerosis. No Nkx2‐5 was detected in normal arteries; however, it was abundantly present in the intima of atherosclerotic lesions and localized in macrophages and smooth muscle cells. …”
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Attenuating ABHD17 Isoforms Augments the S-acylation and Function of NOD2 and a Subset of Crohn’s Disease-associated NOD2 VariantsSummary by Charneal L. Dixon, Noah R. Martin, Micah J. Niphakis, Benjamin F. Cravatt, Gregory D. Fairn

“…Inhibiting ABHD17 increased the plasma membrane localization of wild-type NOD2 and a subset of poorly acylated Crohn’s disease-associated variants. …”
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Dapagliflozin ameliorates kidney injury following limb ischemia-reperfusion via the AMPK/SIRT1/NLRP3 pathway by Qiuxiao Zhu, Huiyao Hao, Ya Gao, Na Li, Zibo Liu, Linyi Shu, Qian Wang, Lihui Zhang

“…Limb ischemia-reperfusion (I/R) results in both localized tissue harm and injury to distant organs, particularly affecting the kidneys and leading to acute kidney injury. …”
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Spatiotemporal Dynamics of Habitat Quality in Semi-Arid Regions: A Case Study of the West Songnen Plain, China by Hao Yu, Zhimin Liang, Rong Zhang, Mingming Jia, Shicheng Li, Xiaoyan Li, Huiying Li

“…The results showed the following: (1) Habitat quality exhibited a continuous decline during the study period, following a “degradation–recovery” trajectory with deterioration peaking in 2010; the low- and poor-quality habitats predominantly distributed in the central areas characterized by severe salinization, interspersed with patches of good-quality habitat. (2) The degradation of habitat quality was mainly concentrated in natural land cover types, whereas improvements were observed locally in farmland and bare land. However, slight opposite trends were detected between the mean habitat quality values and the habitat change areas in forests, waters, and bare land. …”
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Electrical-gain-assisted circularly polarized photodetection based on chiral plasmonic metamaterials by Chenghao Chen, Zhenhai Yang, Tianyi Hang, Yining Hao, Yijing Chen, Chengzhuang Zhang, Jiong Yang, Xiaoyi Liu, Xiaofeng Li, Guoyang Cao

“…We demonstrate a CPL detector based on “S”-shaped chiral Ag nanowires/InAs/Si heterostructures, where the meticulous construction of the “S”-shaped chiral Ag nanowires with the overlaying InAs channel enables a substantial absorption asymmetry in InAs due to differentiated localized surface plasmon resonances excited by left- and right-circularly polarized (LCP and RCP) light. …”
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A mass spectrometry-based strategy for investigating volatile molecular interactions in microbial consortia: unveiling a Fusarium-specific induction of an antifungal compound by Antonio Azzollini, Antonio Azzollini, Antonio Azzollini, Barbara Sgorbini, Nicole Lecoultre, Carlo Bicchi, Jean-Luc Wolfender, Jean-Luc Wolfender, Patrizia Rubiolo, Katia Gindro

“…For agar-diffused metabolites, imaging mass spectrometry can help overcome this obstacle by localizing the induced molecules during fungal confrontations. …”
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Identification of QTLs associated with opaque2 modifiers influencing kernel opacity, kernel hardness, and tryptophan content in quality protein maize by Diksha Jasrotia, Sushil Kumar, Yashmeet Kaur, Yashmeet Kaur, Abhijit Kumar Das, Alla Singh, Dharam Paul, Shanu Shukla, Priti Sharma, Sujay Rakshit, Ramesh Kumar

“…These QTLs co-localized with candidate genes (opaque1, opaque11, floury1, floury2, floury4, mucronate1, and waxy1). …”
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The characteristics of brain function alterations in patients with chronic prostatitis/chronic pelvic pain syndrome across varying symptom severities evaluated by NIH-CPSI by Shengyang Ge, Yunting Xiang, Xuyun Hua, Zening Wang, Qingfeng Hu, Yijun Guo, Jingqiang Huang, Chengpeng Zhao, Jiajia Wu, Xianli Wang, Chuanyu Sun

“…Analysis using ReHo and DC revealed that brain alterations associated with varying symptom severities were localized in pain perception and modulation regions. …”
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Von Hippel-Lindau (VHL) Protein Antagonist VH298 Improves Wound Healing in Streptozotocin-Induced Hyperglycaemic Rats by Activating Hypoxia-Inducible Factor- (HIF-) 1 Signalling by Shuo Qiu, Yachao Jia, Yunchu Sun, Pei Han, Jia Xu, Gen Wen, Yimin Chai

“…HIF-1α and hydroxy-HIF-1α protein levels in VH298-treated rat fibroblasts (rFb) were measured by immunoblotting, rFb proliferation was detected by the CCK-8 assay, and mRNA levels of related genes were measured by quantitative RT-PCR. …”
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Feline vector-borne pathogens in Iran by Alireza Sazmand, Mariaelisa Carbonara, Leili Moradi, Pardis Almasi, Shiva Saruei, Mozhdeh Moradi-Jam, Anahita Akhondi, Parmida Malekzadeh, Soheila Ghaharzade-Mahabadi, Amin Bakhshani, Omid Chashnigir, Baharak Akhtardanesh, Hamidreza Moosavian, Mohammad Ramezani, Darioush Shirani, Livia Perles, Jairo Alfonso Mendoza-Roldan, Zainab Sadeghi-Dehkordi, Reza Nabavi, Fateme Jalousian, Domenico Otranto

“…-infected cats were detected from the east, center, and west of the country, while D. immitis-positive animals lived in central-north areas. …”
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Distinct Molecular Epidemiology, Transmission Patterns, and Resistance Mutations of HIV-1 Subtypes A1, A6, and A7 in Bulgaria by Aleksandra Partsuneva, Anna Gancheva, Reneta Dimitrova, Lyubomira Grigorova, Asya Kostadinova, Maria Nikolova, Radoslava Emilova, Nina Yancheva, Rusina Grozdeva, Ivailo Alexiev

“…A7 was rare (1.5%, 2/132), detected in 2003 and 2011. Transmission patterns varied: A1 was linked to men who have sex with men (MSM) (62.1%), while A6 was primarily heterosexual (HET) (82.8%) with a balanced gender distribution (56.3% male, 43.8% female). …”
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Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis by Yu Zhang, Rong Wu, Xi Zhan, Xuan-Yi Wang, Lin-Wei Xiang, Ya-Qian Duan, Yan You, Jian-Bo Zhang, Rui Wu, Yun-Yuan Zhang, Liang Duan

“…Confocal imaging revealed that AIM2 was mainly localized to hepatic macrophages, indicating that hepatic macrophages were the major cell type that underwent pyroptosis. …”
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Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway by Qiuhong Jiao, Xiufeng Xu, Longwu Xu, Yuying Wang, Shulan Pang, Jie Hao, Xiaohong Liu, Yudan Zhao, Wanpeng Qi, Limin Qin, Tao Huang, Jingtian Li, Tao Wang

“…Hematoxylin eosin (H&E) staining was used to assess the morphological changes of pulmonary arteries in rats of each treatment group. Co-localization of eIF3a with alpha-small muscle action (α-SMA) and co-localization of eIF3a with endothelial marker (CD31) were detected by double-label immunofluorescence. …”
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The functional roles of deoxyelephantopin potential target circTNPO3 in regulating pancreatic cancer malignant phenotype and gemcitabine chemoresistance via miR-188-5p/CDCA3/TRAF2-... by Daolin Ji, Daolin Ji, Jia Liu, Yanhui Zhang, Yanhui Zhang, Li Hou, Haonan Feng, Xue Xing, Deming Guan, Tiangang Cui, Yi Xu, Yi Xu, Yi Xu, Gang Tan

“…The relationship between CDCA3, TRAF2 and NF-κB-p65 was analyzed using Pearson correlation, and the expression was detected using immunoblotting. The nucleus translocation of p65 was evaluated using IF assay. …”
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