Exudative perifoveal vascular anomalous complex (ePVAC) resembling lesion in a patient with adult-onset foveomacular vitelliform dystrophy by Serena Milan, Marco Rocco Pastore, Andrea Gaggino, Silvia Rinaldi, Daniele Tognetto

“…OCT angiography permitted to localize the lesion flow signal at the deep capillary plexus (DCP) and the avascular slab; choriocapillaris structure was unaffected; any retino-choroidal anastomosis was detected. …”
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A novel GJA3 mutation causing autosomal dominant congenital perinuclear cataracts by Yanan Zhu, Nanlan Li, Ke Yao, Wei Wang, Jinyu Li

“…The GJA3 gene was acquired from a human lens cDNA library, and the GJA3 mutant was generated by PCR-based site-directed mutagenesis. Connexin localization and gap junction formation were assessed by fluorescence microscopy, and hemichannel functions were analyzed by dye uptake assay. …”
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Graduate Student Literature Review: The DRB3 gene of the bovine major histocompatibility complex—Discovery, diversity, and distribution of alleles in commercial breeds of cattle an... by Thales Eduardo Galdino Andrade, Maurício Scavassini Peña, Jéssica Fiorotti, Renan de Souza Bin, Alexandre Rodrigues Caetano, Timothy Connelley, Isabel Kinney Ferreira de Miranda Santos

“…The first evidence of MHC in bovines pointed to a locus containing 2 antigens, one detected by cytotoxic antiserum (MHC class I) and another studied by mixed lymphocyte culture tests (MHC class II). …”
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ZEB1 expression in Th17 cells correlated with p-STAT3 in human apical periodontitis by Xiaoyue Sun, Jingwen Yang, Zijun Wang, Qing Nie, Qian Yang, Wei Zhang, Mingwen Liu, Li Wang, Lingxin Zhu

“…The expression of ZEB1 was detected and analyzed by immunohistochemistry. The localization of ZEB1 in Th17 cells and its colocalization with p-STAT3 were assessed using fluorescence colocalization. …”
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Cancer stem cells are new vistas for predicting the course of breast cancer by E. A. Maslyukova, S. I. Zabroda, L. I. Korytova, K. M. Pozharissky, G. A. Raskin, O. V. Korytov

“…The investigation enrolled 83 locally advanced BC (T1–4N0–3M0) patients treated in 2005 to 2009. …”
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The plant-beneficial fungus Trichoderma harzianum T22 modulates plant metabolism and negatively affects Nezara viridula by Sara Van Hee, Alejandro E. Segurado Luchsinger, Antonino Cusumano, Joleen Masschelein, Hans Jacquemyn, Bart Lievens

“…Metabolite-level effects were primarily observed in damaged leaves, suggesting that the priming effect mainly results in localized metabolite accumulation at the site of attack. …”
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The association of maternal thyroid function with placental hemodynamics during pregnancy by O.S. Paienok, R.G. Protsiuk, A.V. Paienok, B.V. Zadorozhna, B.R. Hrytsyshyn, S.V. Ihnatovych

“…The placenta was studied with the characteristics of ultrasound placentography, placental maturation disorders, the area and localization were determined, and pathological changes in the placental tissue were detected. …”
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Variation and QTL Analysis of Dynamic Tillering in Rice Under Nitrogen and Straw Return Treatments by Yang Shui, Faping Guo, Youlin Peng, Wei Yin, Pan Qi, Yungao Hu, Shengmin Yan

“…Among them, the phenotypic contribution of mks1-355 (<i>qD1tn1-3</i>) and mks1-352 (<i>qD2TN1-2</i>) both exceeded 40%. (2) Multi-environmental QTL analysis detected 15 QTLs. Of these, <i>qmD1TN1</i> (mks1-356) showed no environmental interaction effect, while <i>qmD1TN12</i> (mks12-267), <i>qmD2TN1</i> (mks1-334), <i>qmD2TN3-1</i> (mks3-105), and <i>qmD5TN6</i> (mks6-71) exhibited antagonistic pleiotropy, suggesting that these QTL need to be considered for environmental specificity in breeding. (3) Meta-QTL analysis localized 52 MQTLs, of which MQTL3.1 and MQTL6.8 contained 82 and 59 candidate genes, respectively, and no reported tiller-related genes were found. (4) mks1-355 (<i>qD1tn1-3</i>), mks1-352 (<i>qD2TN1-2</i>), and mks1-356 (<i>qmD1TN1</i>) may be located in the same genetic locus, and their phenotypic contributions were more than 40%. …”
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PERIODONTOLOGICAL STATUS OF PATIENTS WITH DENTOMAXIMAL ANOMALIES BEFORE ORTHODONTIC TREATMENT by V.S. Melnyk, K.V. Zombor, S.V. Melnyk

“…The 1st class of gum recession in the area of the incisors was detected in 40% of cases; the 1st class of recession in the area of premolars 17%; the 2nd class of gum recession in the area of incisors 10%, with 4th class of gum recession localized in incisors and premolars, met with the same frequency in 16% of cases. …”
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A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome by Xiaoxiao Wang, Yingxue Liu, Guanghui Yuan, Jingjie Yang, Xiaowen Liu, Shuyuan Chen, Huaiqian Dou, Panpan Lu, Linfang Han, Duan Li, Cuifang Hao

“…The effects of the ZP1 and ZP3 variants on protein expression were probed via western blotting, and the effects of the variants on protein localization were probed by immunofluorescence. ELISA and Co-IP were used to detect the effects of variants on protein secretion and interactions. …”
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Cloning of the Ajcaspase-8 Gene and Its Temporal Expression and Distribution Analyses During Embryonic Development in the Sea Cucumber Apostichopus japonicus by Xiaojing ZHANG, Chanchan ZHANG, Deyou MA, Jiayi LIANG, Meizhu YAO, Ziji LI

“…Moreover, the expression localization of Ajcaspase-8 and the occurrence of cell apoptosis in metamorphosizing larvae were determined via whole embryo hybridization and TUNEL techniques, respectively. …”
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Phylogenetic and functional analysis of MYB genes unraveling its role involved in anthocyanin biosynthesis in H macrophylla by Yingying Liao, Wenwen Zhao, Yu Wang, Sumeiqi Zhao, Shiqin Gu, Chao Zhang, Jiqing Peng, Song Sheng, Sen Wang

“…Predominantly, MYB proteins were localized within the nucleus, although some were also detected in other organelles, indicating a multifaceted role in cellular function. …”
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An improved method for whole-mount in situ hybridization in regenerating tails of Xenopus laevis tadpoles by A. D. Shitikov, E. A. Parshina, A. G. Zaraisky, A. G. Zaraisky, M. B. Tereshina, M. B. Tereshina

“…The validation of these data and further examination using WISH offers the advantage of providing detailed information on the spatial and temporal dynamics of target gene expression levels. However, detecting mRNA by WISH can be challenging when mRNA levels are very low, transcripts are localized in hard-to-access areas, or tissue samples are prone to background staining, as is the case with X. laevis regenerating tail samples. …”
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GALNTL5, which is restricted to mouse spermatids, impairs endoplasmic reticulum (ER) function through direct interaction with ER chaperone proteins by Nobuyoshi Takasaki, Yoshihiro Koya, Mamoru Yamashita, Akihiro Nawa

“…Moreover, heterozygotic deletions of human GALNTL5 have been detected in patients diagnosed with asthenozoospermia (low sperm motility). …”
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NON-HODGKIN'S LYMPHOMAS OF FEMALE REPRODUCTIVE SYSTEM by A. V. Babkina, B. O. Toloknov, O. V. Kamaeva, I. I. Bokin, A. R. Shafiev, I. V. Poddubnaya

“…Most of patients were fertile (60%, n=24). Such tumors was localized in breast in 40% of cases (n=16), in ovaries - 20% (n=8), in uterine corpus - 12,5% (n=5), in uterine cervix - 15% (n=6), and in vagina - remaining 12,5% (n=5). …”
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Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts. by Anne Grünewald, Lisa Voges, Aleksandar Rakovic, Meike Kasten, Himesha Vandebona, Claudia Hemmelmann, Katja Lohmann, Slobodanka Orolicki, Alfredo Ramirez, Anthony H V Schapira, Peter P Pramstaller, Carolyn M Sue, Christine Klein

“…The mitochondrially localized E3 ubiquitin-protein ligase Parkin has been reported to be involved in respiratory chain function and mitochondrial dynamics. …”
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Effects and safety of high-frequency repetitive transcranial magnetic stimulation in trigeminal neuralgia by A. G. Poydasheva, I. S. Bakulin, D. Yu. Lagoda, N.   A.  Suponeva, M.  A.   Piradov

“…Significant changes were detected in the physical health measure of SF‑36 quality of life questionnaire, particularly, in the “bodily pain” domain, as well as in such aspects of the mental health measure as “vitality” and “social functioning”. …”
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Individual approach to the treatment of patients with stage III–IV laryngeal and laryngopharyngeal cancer in the Altai territory by A. A. Frolova, A. S. Petrikov, G. M. Glickenfreud, I. V. Vikhlyanov, S. S. Glotov, T. V. Sharobarova

“…Group I patients (n=50) with locally advanced laryngeal cancer underwent laryngectomy followed by radiation therapy with a total dose of 54 Gy delivered to the bed of the removed tumor and lymph node drainage region. …”
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Holocord syringomyelia in 18 dogs by Despoina Douralidou, Lorenzo Mari, Sophie Wyatt, Juan Jose Minguez, Patricia Alvarez Fernandez, Carlo Anselmi, Christoforos Posporis

“…The most common neuroanatomical localization was C1-C5 spinal cord segments. On MRI, the cranial limit of HSM was at C1 vertebra in seven (39%) and at C2 in 11 dogs (61%). …”
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Comparative proteomic study of pig muscle proteins during growth and development of an animal by A. G. Akhremko, E. S. Vetrova

“…When examining the muscle tissue of mature pigs, 15 of those proteins were found; the differences were mostly detected in the minor protein fractions. The mass spectrometric analysis of the cut bands with well-pronounced differences from the onedimensional electrophoretogram revealed 214 proteins involved to a greater extent in cellular and metabolic processes, physical activity and localization. …”
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