Chemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosis. by Tale Sliedrecht, Chao Zhang, Kevan M Shokat, Geert J P L Kops

“…Mps1 inhibition precludes Mad1 localization to unattached kinetochores but also accelerates mitosis. …”
Get full text

Identification of an IRF8 gene in common carp (Cyprinus carpio. L) and its regulatory role in immune responses by Yaoyao Zhu, Guiwen Yang

“…Quantitative RT-PCR analysis showed that ccIRF8 transcripts were detectable in all investigated tissues of healthy fish with the highest level in spleen. …”
Get full text

Clinical and genetic characteristics of distal arthrogryposis caused by mutations in the PIEZO2 gene by T. V. Markova, E. L. Dadali, S. S. Nikitin, A.  F . Murtazina, O. L.  Mironovich, I.  V.   Kanivets

“…The previous assumption was confirmed that heterozygous mutations are more often localized in exon 52 of the PIEZO2 gene and disrupt the amino acid sequence of the C‑terminal region of the protein molecule, while in patients with an autosomal recessive mode of inheritance of the mutation, the N‑terminal region is more often found.…”
Get full text

Temporal Lobe Epilepsy with Bitemporal Interictal Epileptiform Discharges: Effects of Sleep and Wakefulness by Amayak G. Broutian, Mariya A. Glazova, Marina Yu. Maksimova, Alexandra I. Belyakova-Bodina

“…The minimum IEA values were recorded during REM sleep; nevertheless, most of the REM sleep discharges were detected on the PS. DPI values were the highest and the most stable during N2 and N3 stages. …”
Get full text

Major Complications Associated With Cerebrospinal Fluid Collection in 11 Dogs: Clinical Presentation and Imaging Characteristics by Cecilia‐Gabriella Danciu, Alana McCarthy, Abbe Crawford

“…The most common neuroanatomical localization was multifocal (5/11). Nine dogs underwent magnetic resonance imaging (MRI) of the head and one dog had radiographs of the cervical vertebral column before CSF collection. …”
Get full text

Classification and lateralization of temporal lobe epilepsies with and without hippocampal atrophy based on whole-brain automatic MRI segmentation. by Shiva Keihaninejad, Rolf A Heckemann, Ioannis S Gousias, Joseph V Hajnal, John S Duncan, Paul Aljabar, Daniel Rueckert, Alexander Hammers

“…Structures discriminating between patients and controls were mainly localized ipsilaterally to the presumed seizure focus. …”
Get full text

Gene conversion in incontinentia pigmenti: a Chinese case series by Lai Ting Leung, Stephanie Ho, Pui Tak Kris Yu, Tsz Shun Myth Mok, Fai Man Ivan Lo, Sze Wing Shirley Cheng, Ho Ming Luk

“…These males either had the IKBKGP1 variant detected in peripheral blood with no IKBKG variant, suggesting possible postzygotic somatic gene conversion confined to localized skin cells or somatic mosaicism. …”
Get full text

Estimation of radiation doses on lymphocytes and their progenitors after ingestion of strontium-89,90 by E. I. Tolstykh, M. O. Degteva

“…In addition, stable chromosomal aberrations (translocations) are detected in them years and decades after radiation exposure. …”
Get full text

To remove or not to remove: Intraconal metallic foreign body following perforating ocular injury by Kumudini Subedi, Sangita Pradhan, Raghunandan Byanju

“…Conclusion: A high degree of clinical suspicion is necessary to detect and localize IOFB. Non-toxic intra-orbital FB may be left in the context of good vision in the affected eye and possible iatrogenic optic nerve damage. …”
Get full text

Ugd Is Involved in the Synthesis of Glycans of Glycoprotein and LPS and Is Important for Cellulose Degradation in <em>Cytophaga hutchinsonii</em> by Wenxia Song, Shaoqi Geng, Qingsheng Qi, Xuemei Lu

“…Additionally, the outer-membrane localization of Cel9A was affected in the mutant. Besides this, Ugd was also important for the synthesis of O-antigen of lipopolysaccharide (LPS). …”
Get full text

Characterization of fetal antigen 1/delta-like 1 homologue expressing cells in the rat nigrostriatal system: effects of a unilateral 6-hydroxydopamine lesion. by Rémy Liechti, Angélique D Ducray, Pia Jensen, Stefano Di Santo, Stefanie Seiler, Charlotte H Jensen, Morten Meyer, Hans Rudolf Widmer

“…Surprisingly, increased numbers of FA1/dlk1-ir cells (by 70%) were detected in dopamine-depleted striata as compared to unlesioned controls. …”
Get full text

Temporal variation in habitat quality shapes the distribution–abundance relationship in waterbirds at landscape scale by Constantinos Charalambous, Petr Musil, Mathilde Legoguelin, Zuzana Musilová, David Hořák

“…Abstract The distribution–abundance relationship (DAR) is a well‐established macroecological pattern, where more locally abundant species are also more widespread across landscapes. …”
Get full text

Effects of Motor Preparation on Walking Ability in Active Ankle Dorsiflexion by Hiroki Ito, Hideaki Yamaguchi, Ryosuke Yamauchi, Ken Kitai, Kazuhei Nishimoto, Takayuki Kodama

“…Results: The Cz-TA CMC (beta frequency band) during active ankle dorsiflexion successfully detected significant differences in the maximum dorsiflexion angle, inversion angular velocity, brain activity localization, and variations in Cz beta power values during the transition from motor preparation to execution. …”
Get full text

Integrated Transcriptome Analysis Reveals the Lung miRNA–mRNA Regulatory Network Associated with Avian Pathogenic <i>E. coli</i> Infection by Huan Li, Jishuang Tan, Xiaoyi Li, Susan J. Lamont, Hongyan Sun

“…Avian pathogenic <i>E. coli</i> (APEC), one of the most common pathogens, can cause localized or systemic infections and lead to significant economic losses in the poultry industry annually. …”
Get full text

MULTI-WAVE ULTRASONIC CONTROL OF CONCRETE by D. Yu. Snezgkov, S. N. Leonovich

“…Responsivity of the Rayleigh wave parameters to near surface concrete defects permits quickly and efficiently to detect crack areas in a reinforced structure. Energy localization of a surface wave in a layer having width λ/2–λ provides a possibility to ignore reinforcement availability under appropriate selection of oscillation frequency. …”
Get full text

T cells' immunological synapses induce polarization of brain astrocytes in vivo and in vitro: a novel astrocyte response mechanism to cellular injury. by Carlos Barcia, Nicholas S R Sanderson, Robert J Barrett, Kolja Wawrowsky, Kurt M Kroeger, Mariana Puntel, Chunyan Liu, Maria G Castro, Pedro R Lowenstein

“…The MTOC, the organizer of cell polarity, is localized to the base of the protrusion, and Golgi stacks are distributed throughout the protrusion, reaching distally towards the immunological synapse. …”
Get full text

Differential expression of Gnαq gene in white and black skin tissues of mice by Yin Zhihong, Xia Yu, Zhao Xin, Wang Zhun, Lu Jieli, Pang Quanhai

“…The localizations of Gnαq protein were analyzed by immunohistochemistry in different color skin tissues of mice.A partial sequence of Gnαq gene with the length of 140 bp was successfully amplified by PCR. …”
Get full text

Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae. by María-José Ferrándiz, Pablo Hernández, Adela G de la Campa

“…Remarkably, inhibition of RNAP with rifampicin prevented the localization of TopoI at promoters and, vice versa, inhibition of TopoI with seconeolitsine prevented the binding of RNAP to promoters. …”
Get full text

Strategy of satellite monitoring of organic carbon content in arable soil horizons in Russia by I. Yu. Savin, E. Yu. Prudnikova, G. V. Windecker, N. S. Sobolev

“…But, except for rather schematic global approaches, monitoring at the detailed level is still localized, and the constructed models cannot be extrapolated to other territories. …”
Get full text

Late diagnosis of primary chronic adrenal insufficiency in the framework of autoimmune polyglandular syndrome type 2. Clinical observation by V. G. Chobitko, A. P. Belova

“…If the pathological process is localized in the adrenal glands themselves, causing almost total destruction of the cortical layer (at least 90% of the cortex of both adrenal glands), a clinical picture of primary chronic adrenal insufficiency (1-HH) develops. …”
Get full text