Lipid-Polymer Hybrid Nanoparticles as a Smart Drug Delivery System for Peptide/Protein Delivery by Alharith A. A. Hassan, Eslam Ramadan, Katalin Kristó, Géza Regdon, Tamás Sovány

“…Liposomes and other lipid-based nanocarriers show excellent biocompatibility and the ability to encapsulate hydrophobic and hydrophilic drugs; however, they often suffer from poor structural stability, premature leakage of the loaded drugs, and poor encapsulation efficiency for macromolecular peptides and proteins. …”
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Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers. by Fanny Chereau, Yoann Madec, Caroline Sabin, Niels Obel, Ezequiel Ruiz-Mateos, Georgios Chrysos, Sarah Fidler, Clara Lehmann, Robert Zangerle, Linda Wittkop, Peter Reiss, Osamah Hamouda, Vicente Estrada Perez, Manuel Leal, Amanda Mocroft, Patricia Garcia De Olalla, Adriana Ammassari, Antonella D'Arminio Monforte, Cristina Mussini, Ferran Segura, Antonella Castagna, Matthias Cavassini, Sophie Grabar, Philippe Morlat, Stéphane De Wit, Olivier Lambotte, Laurence Meyer, HIV Controllers Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCOORD

“…<h4>Methods</h4>HICs were identified in COHERE on the basis of ≥5 consecutive viral loads (VL) ≤500 copies/mL over ≥1 year whilst ART-naive, with the last VL ≤500 copies/mL measured ≥5 years after HIV diagnosis. …”
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Replacing Gauges with Algorithms: Predicting Bottomhole Pressure in Hydraulic Fracturing Using Advanced Machine Learning by Samuel Nashed, Rouzbeh Moghanloo

“…Ensuring the overall efficiency of hydraulic fracturing treatment depends on the ability to forecast bottomhole pressure. It has a direct impact on fracture geometry, production efficiency, and cost control. …”
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Reinforced locking screws with enhanced head and neck junction: improving biomechanical stability in opening-wedge high tibial osteotomy applications by Kyung-Wook Nha, Hyungsuh Kim, Kyoung-Tak Kang, Jae Gyoon Kim, Hyung Jun Park

“…In the compression test, they exhibited a higher load to failure (909.0 ± 30.4 N vs. 757.5 ± 46.2 N, p < 0.001). …”
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On ensuring joint tightness on the basis of technological induction by G. A. Pilyushina, P. G. Pyrikov, E. A. Pamfilov, V. V. Kapustin

“…A drop in the magnitude of the magnetic flux was observed when the compound was under the on-load operation for 268 hours. The total operating time of the joint was 1070 hours. …”
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A Super-Assembled Synergistically Nanoplatform AP@ZIF-8Pt for Hepatocarcinoma Therapy by Luo Z, Wang D, Lin L, Zhou R, Su Y, Zhang Z, Hu J, Dai Y, Wu J, Huang X, Zhou Y, Gong L

“…Herein, a three-step intelligent biodegradable drug delivery nanoplatform was designed.Methods: First, a hollow ZIF-8 was synthesized, embedded with platinum nanoparticle to form ZIF-8Pt, and then loaded with AP, and lastly formed AP@ZIF-8Pt, which possess pH-responsive drug release and cancer-targeted ability.Results: As expected, both in vitro and in vivo experiment demonstrated that AP@ZIF-8Pt performed treatment effects in hepatocarcinoma through relieving tumor-hypoxic microenvironment, inhibiting cell proliferation and promoting cell apoptosis. …”
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The use of Epoxy-Gravel Composites to Harden Composite Ploughshares with the Possibility of Restoring the Components Having Radial Wear by Igor N. Kravchenko, Sergey A. Feskov, Petr V. Senin, Pavel V. Chumakov, Alexander A. Gutsan

“…The study is aimed at substantiating the practical application of epoxygravel composites to harden composite ploughshares with the ability to restore the components having radial wear. …”
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Urban Toponyms as Linguistic Markers of “Owning” the Space by Natalia Vasiljeva

“…Vernacular regions are loaded with not only territorial, but also social and emotional sense and relate to mental maps. …”
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Preparation and Characterization of Hydrophobin 4-Coated Liposomes for Doxorubicin Delivery to Cancer Cells by Fatma Hande Osmanagaoglu, Aysegul Ekmekcioglu, Busel Ozcan, Gunseli Bayram Akcapinar, Meltem Muftuoglu

“…<b>Background:</b> The properties of nanoparticle surfaces are crucial in influencing their interaction with biological environments, as well as their stability, biocompatibility, targeting abilities, and cellular uptake. Hydrophobin 4 (HFB4) is a class II HFB protein produced by filamentous fungi that has a natural ability to self-assemble at hydrophobic-hydrophilic interfaces. …”
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Environmental Assessment of the Sulfate Content in the Air of the City of Stavropol Using Bioindication Methods by V. V. Movsesova, A. S. Bluzhina, I. A. Bakumenko

“…Zone 1- Victory Park, Taman Forest, Central Park, Demino MDC, these areas were selected as background points, they are experiencing minimal technogenic load and are characterized by low sul-fate content in the tree bark;Zone 2 with average sulfate content in the tree bark includes: ul. …”
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Discovery of Biofilm-Inhibiting Compounds to Enhance Antibiotic Effectiveness Against <i>M. abscessus</i> Infections by Elizaveta Dzalamidze, Mylene Gorzynski, Rebecca Vande Voorde, Dylan Nelson, Lia Danelishvili

“…<b>Background/Objectives</b>: <i>Mycobacterium abscessus</i> (MAB) is a highly resilient pathogen that causes difficult-to-treat pulmonary infections, particularly in individuals with cystic fibrosis (CF) and other underlying conditions. Its ability to form robust biofilms within the CF lung environment is a major factor contributing to its resistance to antibiotics and evasion of the host immune response, making conventional treatments largely ineffective. …”
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Development and Performance Evaluation of Enhanced Piezo-Electric Sensor Cum Energy Harvester Based on Flexural Strain Amplification in Real-Life Field Conditions by Sreenitya Singamsetty, Naveet Kaur, Suresh Bhalla

“…This article examines the influence of the geometric properties of TSAH on strain amplification via numerical investigations under a specific set of external loads. Based on numerical studies, the sensors are bonded to the trapezoidal strain-amplifying plate to develop and assess the TSAH. …”
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Seamless Integration of Grid-Forming and Grid-Following Capabilities in a Single VSI Within a Unified Hybrid Control Framework Under Islanded Conditions by Iman Lorzadeh, Omid Lorzadeh, Dimitar V. Bozalakov, Luc Dupre, Lieven Vandevelde

“…Under the tested islanded operating conditions, VSIs equipped with the UHC scheme demonstrate the ability to mimic virtual inertia, contributing to voltage and frequency stability during sudden load changes, reference power variations, line outages, and short-circuit fault scenarios with appropriate dynamic and transient responses, addressing the specific challenges of islanded microgrid stability and control. …”
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Time in range prediction using the experimental mobile application in type 1 diabetes by A. N. Rusanov, T. I. Rodionova

“…On the base of included records, TIR(CGM) was calculated and training models of 7-point SMBG profiles were generated. SMBG profiles’re loaded into the developed experimental mobile application that calculated standard glycemic control parameters. …”
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The stabilizing potential of the supraspinatus is inhibited in tear-associated scapula shapes but can be modulated by kinematic adjustments by Erin C. S. Lee, Nathan M. Young, Ellen Y. Li, Rebekah L. Lawrence, Michael J. Rainbow

“…Mechanisms that increase the supraspinatus load required to perform this stabilizing function may increase an individual's susceptibility to tears. …”
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NAF-MEEF: A Nonlinear Activation-Free Network Based on Multi-Scale Edge Enhancement and Fusion for Railway Freight Car Image Denoising by Jiawei Chen, Jianhai Yue, Hang Zhou, Zhunqing Hu

“…Railwayfreight cars operating in heavy-load and complex outdoor environments are frequently subject to adverse conditions such as haze, temperature fluctuations, and transmission interference, which significantly degrade the quality of the acquired images and introduce substantial noise. …”
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The internalized stigma, self-efficacy, occupational competence and employment outcome among persons with severe mental illness under one-to-one peer support services in Taiwan by Kan-Yuan Cheng, Yi-Lin Wang, Wen-Chun Hung, Chia-Feng Yen

“…Conclusions Participation in the program enhanced PSWs’ ability to manage environmental challenges, while service users experienced an improvement in income following one-on-one peer support services. …”
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VCNet: Optimized Deep Learning framework with deep feature extraction and genetic algorithm for multiclass rice crop disease detection by Sanam Salman Kazi, Bhakti Palkar, Dhirendra Mishra

“…Convolution Neural Networks (CNN) are best in their ability to detect rice diseases but still face challenges in generalizing equally well for all classes of disease in multiclass classification. …”
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Crosstalk of lactate metabolism-related subtypes, establishment of a prognostic signature and immune infiltration characteristics in colon adenocarcinoma by Wenwei Xu, Yongjian Li, Zhaoshang Zeng, Guanjun Guo

“…An validation cohort was used to validate the predictive ability of risk signature and expression of 6 candidate LRGs was confirmed through quantitative real-time PCR (qRT-PCR). …”
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Interface design and interaction optimization for spatial computing 3D content creation and immersive environment generation using Apple Vision Pro by Jie Fu, Mick Grierson, Renpeng Jiang, Shun Fu, Mengzhi He, Muhan Xu

“…Traditional 3D content creation paradigms present significant barriers to meaningful creative expression in XR environments, limiting designers' ability to iterate fluidly between conceptual thinking and spatial implementation. …”
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