-
841
Validity and reliability of a physical literacy knowledge, attitudes, self-efficacy and behaviors questionnaire for early childhood educators (PLKASB-ECE): An exploratory factor an...
Published 2024-01-01“…The 15 items were subjected to exploratory factor analysis and resulted in a five-factor scale with one item not loading. The five-factor scale held with the final 14 items with loadings ranging from 0.481 to 0.886, Cronbach's alpha ranging from 0.70 to 0.82, with ordinal omega ranging from 0.72 to 0.82. …”
Get full text
Article -
842
HC-Pro inhibits HEN1 methyltransferase activity, leading to autophagic degradation of AGO1
Published 2025-03-01“…Fluorescence resonance energy transfer (FRET) analysis indicated that HC-ProTu recruits HEN1 and ATG8a to HC-Pro bodies (H-bodies) and indirectly associates with AGO1, potentially influencing the assembly of the RNA-induced silencing complex (RISC) and leading to the accumulation of free-form miRNA duplexes. The ability of HC-ProTu to sequester HEN1 and AGO1 in H-bodies may, therefore, modulate miRNA loading. …”
Get full text
Article -
843
Assessment of CuFeSe2 ternary nanozymes for multimodal triple negative breast cancer theranostics
Published 2025-04-01“…Furthermore, these nanosheets showed remarkable multimodal imaging ability for magnetic resonance imaging (MRI), computed tomography (CT) and infrared thermography in TNBC tumor-bearing mice (4T1 cells). …”
Get full text
Article -
844
Isolated Grid-Forming Control of Wave Energy Converter for Island Electrification
Published 2025-01-01“…The results also demonstrate the converter’s ability to black-start the island load and automatically transition the load current with varying loads in a few milliseconds. …”
Get full text
Article -
845
Biomimetic cancer cell membrane engineered lipid nanoparticles for enhanced chemotherapy of homologous malignant tumor
Published 2025-07-01“…The physicochemical properties of LNPs/D@GBMM were investigated in terms of particle size, morphology, drug loading (DL), drug release behavior and so on. Homologous cellular uptake was evaluated by confocal laser scanning microscopy (CLSM). …”
Get full text
Article -
846
Integrating smart materials in powder melt extrusion 3D printing: Cassava short fiber and polyvinyl alcohol for drug delivery approach
Published 2025-03-01“…PVA, recognized as a smart material, exhibits the ability to change shape in response to stimuli such as heat, pH variations, or water. …”
Get full text
Article -
847
Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction
Published 2025-05-01“…Crosslinked scaffolds showed reduced swelling, slower degradation rates, and increased stiffness, confirming MDo as an effective crosslinking agent. Scaffolds loaded with ciprofloxacin (CFX) demonstrated their ability to deliver therapeutic agents, as the CFX loading capacity was promoted by CHT–CFX interactions. …”
Get full text
Article -
848
Investigations using potentiodynamic polarization measurements, cure durability, ultra violet immovability and abrasion resistance of polyamine cured ilmenite epoxy coating for oil...
Published 2018-09-01“…Accelerated ultra violet (UV) exposure coating test was accomplished to measure the ability of the cured coated films to resist UV weathering and sun light damage. …”
Get full text
Article -
849
Risk Factors for Stress Fractures in Athletes
Published 2025-05-01“…The following keywords were used: stress fractures, risk factors, athletes Conclusions Stress fractures primarily result from excessive bone loading that exceeds the bone's ability to repair microdamage caused by daily activities. …”
Get full text
Article -
850
Improving the functionality of intraoperative nerve monitoring during thyroid surgery: is lidocaine an alternative?
Published 2025-05-01“…All patients were anesthetized with a narcotic analgesic and inhalation anesthetic. The loading dose of lidocaine was administered at the rate of 1 mg/kg intravenously, and the maintenance dose was calculated at 1.5 mg/kg/hour. …”
Get full text
Article -
851
Dual-Drug Delivery Systems Using Hydrogel–Nanoparticle Composites: Recent Advances and Key Applications
Published 2025-07-01“…This approach combines the high loading capacity and tunable release properties of hydrogels with the enhanced stability and targeting ability of nanoparticles, providing synergistic benefits in various biomedical applications. …”
Get full text
Article -
852
Hydrogel applications: a promising frontier in pneumonia therapy
Published 2025-06-01“…Despite these promising developments, challenges related to material safety, drug loading efficiency, and scalability of manufacturing processes must be addressed to facilitate clinical translation. …”
Get full text
Article -
853
Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients.
Published 2016-08-01“…Celgosivir was given as a 400 mg loading dose and 200 mg bid (twice a day) over 5 days. …”
Get full text
Article -
854
Design, construction and efficiency analysis of bagasse-based charcoal packed horizontal lab-scale wetland for the removal of antibiotic-resistant bacteria
Published 2025-07-01“…Biochar was selected as the substrate medium due to its high adsorption capacity and ability to support microbial communities that contribute to contaminant degradation. …”
Get full text
Article -
855
Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab
Published 2025-02-01“…Methods Patients aged 18–65 years with an ICHD-3β diagnosis of CM were randomized 2:1:1 to receive monthly injections of placebo (N = 558), galcanezumab 120 mg with a 240-mg loading dose (N = 278), or galcanezumab 240 mg (N = 277) during a 3-month double-blind period of the phase 3 REGAIN trial. …”
Get full text
Article -
856
Extracellular Vesicles Administered via Intrathecal Injection Mediate Safe Delivery of Nucleic Acids to the Central Nervous System for Gene Therapy
Published 2025-07-01“…Red blood cell‐derived extracellular vesicles (RBCEVs) have the potential to address these challenges due to their non‐immunogenicity, non‐cytotoxicity, ability to be redosed, and suitability for nucleic acid loading. …”
Get full text
Article -
857
Enrichment of impurities seeded for exhaust control in a spherical tokamak power plant geometry
Published 2025-01-01“…Through SOLPS-ITER simulations, we have investigated the ability of seeded argon and neon impurities to effectively control divertor power loading in a power-plant-class spherical tokamak geometry. …”
Get full text
Article -
858
Geometric determinants of sinterless, low-temperature-processed 3D-nanoprinted glass
Published 2025-07-01“…As an exemplar with relevance to biomedical microinjection applications, we harness this new knowledge to DLW-print POSS-based glass microneedle arrays (MNAs) and demonstrate their ability to penetrate into a medium not possible using standard polymer MNAs. …”
Get full text
Article -
859
Camel milk-derived exosomes as novel nanocarriers for curcumin delivery in lung cancer
Published 2024-11-01“…Among these innovations, exosomes, or small extracellular vesicles (EVs), have emerged as promising carriers for drug delivery due to their natural origin and ability to encapsulate both small molecules and biologics. …”
Get full text
Article -
860
Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering
Published 2025-03-01“…Histological analysis confirmed favorable biocompatibility and structural integrity of Insulin-loaded pure Alg and Alg-Cs scaffolds at drug loading levels of up to 20 and 10 μg, respectively. …”
Get full text
Article