Polymeric Nanoparticles Potentiate the Anticancer Activity of Novel PI3Kα Inhibitors Against Triple-Negative Breast Cancer Cells by Suhair Sunoqrot, Samah Abusulieh, Dima Sabbah

“…<b>Results</b>: The NPs exhibited a particle size of 100–200 nm, excellent drug loading efficiencies, and sustained release under physiologic conditions. …”
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Microstructure and dynamic deformation mechanism of laser powder bed fusion of 316L-containing Ti–6Al–4V with dual-phase heterostructure by Kekang Zhang, Jinhui Meng, Yixiong Hu, Zhenduo Chen, Yang Liu

“…Under quasi-static load, the deformation mode of HST alloy is mainly attributed to progressive deformation-induced martensitic transformation. …”
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Polyethylene glycol-phospholipid functionalized single-walled carbon nanotubes for enhanced siRNA systemic delivery by Yuen-Fen Tan, Ling-Wei Hii, Wei-Meng Lim, Soon-Keng Cheong, Chee-Onn Leong, Maxine Swee-Li Yee, Chun-Wai Mai

“…Abstract Small interfering RNAs (siRNA) technology has emerged as a promising therapeutic tool for human health conditions like cancer due to its ability to regulate gene silencing. Despite FDA-approved, their delivery remains localized and limiting their systemic use. …”
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Online Characterization of Internal Stress in Aluminum Alloys During Laser-Directed Energy Deposition by Yi Lu, Jian Dong, Wenbo Li, Chen Wang, Rongqi Shen, Di Jiang, Yang Yi, Bin Wu, Guifang Sun, Yongkang Zhang

“…To validate this method, we used AlSi10Mg material, which has a low melting point and high reflectivity, and developed a high-precision segmentation network based on DeeplabV3+ to test its ability to measure shrinkage in high-exposure images. …”
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Therapeutic and diagnostic implications of exosomes as natural nanoparticles: a new paradigm in brain cancer disease management by Shanid Mohiyuddin, Pankaj Dipankar, Belfin Robinson, Andrew Jeyabose, Andrew Jeyabose, J. Karthikeyan

“…Due to their biological origin, exosomes demonstrate a significant ability to cross the BBB and possess enhanced biocompatibility, high drug-loading capacity, and low immunogenicity. …”
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Strain rate sensitivity metrics of PSU and PPSU high-performance polymers in extrusion-based additive manufacturing by Nectarios Vidakis, Markos Petousis, Nikolaos Mountakis, Maria Spyridaki, Ioannis Valsamos, Emmanuel Kymakis

“…High-performance polymers (HPPs), combined with material extrusion (MEX) additive manufacturing (AM), compile a powerful manufacturing system, suitable to meet the challenges of demanding industries. Their ability to undergo high strain rates is not well investigated yet. …”
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Blasting extrusion pretreatment of sweet sorghum bagasse for enhanced enzymatic saccharification and ethanol production using Pichia kudriavzevii ATCC 20,381 by Benjamín Vázquez-Rodríguez, Erick Heredia-Olea, Adriana Alamilla-Morales, Esther Pérez-Carrillo, David A. Perez-Perez, Sergio O. Serna-Saldívar

“…Fermentation was performed at 28 °C, pH 5.0 and 10% of solids loading (BEP + ES and ES) using the stress tolerant yeast Pichia kudriavzevii ATCC 203,081 for ethanol production. …”
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An eco-friendly synthesis of ZnO nanoparticles with jamun seed extract and their multi-applications by Alqahtani Mohammed S., Syed Rabbani, Shahid Mudassar, Alrashoudi Reem Hamoud, Mateen Ayesha, Lakshmipathy R., Goel Mukesh

“…The ZnO nanoparticles were later investigated for their ability to remediate Hg2+ ions from aqueous solutions. …”
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Preclinical Evaluation of a Growth‐Accommodating Transcatheter Pulmonary Valve System for Young Children by Nnaoma Agwu, Daryl Chau, Gregory S. Kelley, Tanya Burney, Ekaterina Perminov, Christopher Alcantara, Michael R. Recto, Arash Kheradvar

“…Results Benchtop fracture testing and finite element analysis confirmed the stent's ability to be crimped to a 3‐mm diameter for loading into a 12‐Fr transcatheter system and expanded to 20 mm without fracture. …”
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Palladium-catalyzed Suzuki–Miyaura cross-coupling with $\alpha $-aminophosphonates based on 1,3,4-oxadiazole as ligands by Hkiri, Shaima, Touil, Soufiane, Samarat, Ali, Sémeril, David

“…Cross-coupling of aryl chlorides required a catalyst loading of 1 mol% to generate ortho-substituted biphenyls.…”
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Invited perspectives: Integrating hydrologic information into the next generation of landslide early warning systems by B. B. Mirus, B. B. Mirus, T. Bogaard, R. Greco, M. Stähli

“…<p>Although rainfall-triggered landslides are initiated by subsurface hydro-mechanical processes related to the loading, weakening, and eventual failure of slope materials, most landslide early warning systems (LEWSs) have relied solely on rainfall event information. …”
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Advancements in cobalt‐based oxide catalysts for soot oxidation: Enhancing catalytic performance through modification and morphology control by Tingyi Zhao, Zuguo Song, Chengchun Wu, Yuanjun Li, Haoze Li, Yuechang Wei, Siyu Yao, Menglan Xiao, Mingqin Zhao, Bing Cui

“…Compared with cerium oxide which is widely used, cobalt oxide in transition metal oxides has been widely studied in recent years because of its high redox ability and easy to control morphology. This paper elaborates on the influence of modification techniques such as doping, loading, and solid solution on the catalytic performance of cobalt‐based catalysts in soot oxidation. …”
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MiR-145 encapsulated small extracellular vesicles inhibit colorectal cancer progression by downregulating fascin actin-bundling protein 1 expression by Yanxia Chen, Meijuan He, Lei Cui, Jianguo Zhang, Hanpeng Huang, Zhimin Tao

“…Results Our results revealed that the efficient loading of miR-145 into sEVs could be achieved through a dynamic combination of sonication and electroporation. …”
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A data-driven prediction method for shear bearing capacity of flexural-shear type RC column based on PCC-XGB-SHAP by Tao Huang, Chunfeng Wan, Tingbin Liu, Changqing Miao

“…Results indicate that the XGB model has the highest accuracy and robust generalization ability, making it the most suitable ML method for shear capacity prediction. …”
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A new polyazomethine-based pyrazole moiety and its reinforced nanocomposites @ ZnO for antimicrobial applications by Aqilah A. Hakami, Hajar S. Alorfi, Thoraya A. Farghaly, Mahmoud A. Hussein

“…The polymeric nanocomposites were prepared with a 5% loading of zinc oxide nanofiller using the same preparation technique, in addition to the help of ultrasonic radiation. …”
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Research on Stacking Distribution of Steel Plates Input Based on Improved Multi-objective Particle Swarm Optimization by ZHONG Chuanjie, CHENG Wenming, DU Run, GAO Xuchao, ZHANG Lin

“…The simulation results showed that compared to the classical multi-objective algorithms NSGA‒Ⅱ, MOEA/D‒DE, and MOPSO, PCDMOPSO demonstrated clear advantages in optimization ability for each target under different storage scales. …”
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Enhanced Anti-Melanoma Activity of Nutlin-3a Delivered via Ethosomes: Targeting p53-Mediated Apoptosis in HT144 Cells by Arianna Romani, Giada Lodi, Fabio Casciano, Arianna Gonelli, Paola Secchiero, Giorgio Zauli, Olga Bortolini, Giuseppe Valacchi, Daniele Ragno, Agnese Bondi, Mascia Benedusi, Elisabetta Esposito, Rebecca Voltan

“…Notably, ethosomes, regardless of their nutlin-3a loading, exhibited the ability to reduce HT144 melanoma cellular migration, as assessed in real time using xCELLigence, likely due to the modification of lipid rafts, suggesting their potential antimetastatic properties. …”
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Development and study of mucoadhesive microcapsules for the nasal levodopa delivery by D. S. Gordeeva, V. V. Khutoryanskiy, R. I. Moustafine

“…The encapsulation efficiency, % (EE%) and loading capacity, % (LC%) of levodopa loaded MC were assessed using UV spectrophotometry on an Evolution™ 220 device (Thermo Fisher Scientific, USA) at a wavelength of 202 nm. …”
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Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation by Lei Ren, Yangnan Hu, Xiaoqiong Ding, Menghui Liao, Tian Shen, Sixing Cao, Hui Zhang, Hong Cheng, Yanru Qi, Pan Feng, Xinyi Pang, Ling Lu, Huan Wang, Wenwen Liu, Renjie Chai, Lin Cheng

“…It is anticipated that this porous electrode drug‐loading coating may provide a valuable reference strategy for the future cochlear electrode transplantation system.…”
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Sunlight-Induced Photocatalytic Removal of Paracetamol Using Au-TiO₂ Nanoparticles by Lamine Aoudjit, Joana M. Queirós, A. S. Castro, Djamila Zioui, Noelia González-Ballesteros, S. Lanceros-Mendez, Pedro M. Martins

“…The influence of the parameters pH, loading (0.4, 0.8, and 1 g/L), pollutant concentration (20, 30, 40 ppm), and contact time (30, 60, 90, 120, 150, and 180 min) was studied by exposing the NPs to solar radiation. …”
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