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Cord Blood Platelet Lysate-Loaded Thermo-Sensitive Hydrogels for Potential Treatment of Chronic Skin Wounds
Published 2024-11-01“…Conclusions: The developed hydrogels represent promising tools for CSW treatment, with tunable gelation properties and residence time and the ability to encapsulate and deliver active biomolecules with sustained and controlled kinetics.…”
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Sodium alginate microspheres loaded with Quercetin/Mg nanoparticles as novel drug delivery systems for osteoarthritis therapy
Published 2025-03-01“…Furthermore, the antioxidant and anti-inflammatory properties of Que-Mg@SA were evaluated by examining the ROS scavenging ability and pro-inflammatory factors levels, respectively. …”
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Reaction time variations in normal aging and elderly MCI patients under various cognitive load conditions
Published 2025-07-01“…Reaction times in both groups prolonged with increasing cognitive load (p < 0.05), but the delay was more pronounced in the MCI group (p < 0.05). …”
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268
M2 Macrophage‐Derived Extracellular Vehicles‐Loaded Hyaluronic Acid‐Alginate Hydrogel for Treatment of Osteoarthritis
Published 2025-06-01“…To investigate the regulatory effects of M2‐Exo on chondrocytes and Mφ in vitro, and to evaluate the therapeutic effect of the M2‐Exo‐loaded hydrogel system (ALG‐M2Exo) on cartilage damage in a rat OA model. …”
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269
Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization
Published 2025-03-01“…In the present study, we designed an MSC-AB (MSC-derived AB)-loaded polycaprolactone (PCL) scaffold, evaluated the macrophage phenotype and skin wound inflammation in vivo and in vitro, and explored the ability of MSC-AB-loaded PCL scaffolds to promote wound healing. …”
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270
Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma
Published 2024-10-01“…The TTP-PNPs in the form of empty polymer (P), single drug-loaded [P(Gem) and P(PTX)], and dual drug-loaded [P(Gem + PTX)] polymer nanoformulations exhibited stable and homogenous spherical shapes with 110–160 nm size. …”
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271
A novel semi-theoretical model for hydraulic conductivity prediction considering temperature effect
Published 2025-07-01“…A stress-deformation-seepage model considering temperature and cyclic loading history effect is proposed, and the accuracy of the model is verified. …”
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272
Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors
Published 2025-07-01“…Conventional systems are often limited to uniaxial loading, restricting their ability to replicate the complex, multidirectional biomechanics of the spine. …”
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273
Comparative Study of P507-impregnated Polystyrene and Polyacrylate Resins for Separation of Yb/Lu
Published 2025-01-01“…It is confirmed that the microstructure, extractant loading and nuclide separation performance of imported and domestic LN2 resins are significantly different. …”
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Comparative morphometric characteristics of the working surface of endodontic rotary nickel-titanium instruments after maximum cyclic loading
Published 2022-04-01“…The content of pure nickel-titanium alloy along the periphery of the endodontic instrument in Universal protapers ensures high cutting ability of the faces. The obtained data on different resistance to cyclic loads should be taken into account in the endodontic treatment of multi-root teeth. …”
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275
Mechanical response characteristics and damage mechanism of water-containing mudstone under low strain rate dynamic loading
Published 2024-12-01“…The mechanisms of fine-scale structural evolution of mudstones under water-rock and dynamic loading were revealed. The results show that: ① low strain rate dynamic loading still has a weakening effect on the strength of mudstone, the ability of mudstone to resist the disturbance of dynamic loading decreases with the increase of water content, dynamic loading rate, and strength, and the strength damage reaches the maximum of 28.47%, 59.76%, and 31.56%, respectively. ② The acoustic emission characteristic parameter law shows that during the loading process, the mudstone has gone through four fracture evolution stages: initial damage, damage intensification, damage quiescence (exacerbation), and damage development, and the Kaiser effect is more obvious at the lower level of each factor in the dynamic loading perturbation stage, and the Felicity effect is more significant at the higher level of each factor. ③ The loading strain and plastic strain of the mudstone under the initial dynamic load disturbance are the largest, and the time of the second significant damage of the mudstone is advanced at higher levels of each factor. …”
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276
Preparation of composite calcium phosphate cement scaffold loaded with Hedysarum polysaccharides and its efficacy in repairing bone defects
Published 2024-08-01“…Graphical Abstract The composite CPS loaded with HPS-50 is an excellent scaffold with fine load-bearing ability and sustained release of osteogenic factors to repair bone defects.…”
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277
Preparation and Characterization of Dual-Network Multifunctional Hydrogels Based on Peach Gum Polysaccharides: Ultrafast Self-Healing Ability, Favorable Mechanical Tunability, and...
Published 2025-04-01“…In this study, a dual-network oxidized peach gum polysaccharide–carboxymethyl chitosan (OPGC) hydrogels with ultrafast self-healing ability was constructed by self-assembly using oxidized peach gum polysaccharide (OPGP) and carboxymethyl chitosan (CMCS). …”
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278
Particle Size Distribution Controls the Threshold Between Net Sediment Erosion and Deposition in Suspended Load Dominated Flows
Published 2018-02-01“…While current suspended load transport models commonly use a single characteristic particle size, the model developed herein demonstrates that particle size distribution is a critical control on the threshold between erosional and depositional flow. …”
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Hierarchical Cluster Control Method for Flexible Load in Distribution Network Based on Improved Alternating Direction Multiplier Method
Published 2024-01-01“…In order to give full play to the regulation ability of flexible loads in distribution networks, a hierarchical cluster regulation method for flexible loads in distribution networks based on improved alternating direction multiplier method is proposed. …”
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280
Research on Electric Vehicle Charging Load Prediction Methods Combining Signal Noise Reduction and Time Series Modeling
Published 2025-01-01“…These findings confirm the reliability and effectiveness of the proposed model for user charging demand load prediction, showcasing its strong generalization ability and robustness.…”
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