Community-level physiological profiling of carbon substrate metabolization by microbial communities associated to sediments and water in karstic caves from Romania by Diana Felicia PANAIT, Andrei Marian PANAIT, Adorján CRISTEA, Erika Andrea LEVEI, Oana Teodora MOLDOVAN, Horia Leonard BANCIU

“…The latter analysis elucidated non-linear relationships between variables, such as EC, Na, and Mg, and microbial metabolic diversity indices. …”
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Relationships between physical frailty, depressive symptoms, and cognitive ability among community-dwelling older adults in India by T. Muhammad, Manish Kumar, Shobhit Srivastava, Waad Ali

“…Methods We used data from the Longitudinal Aging Study in India, conducted between 2017 and 2019. The analytic sample consisted of 14,652 males and 15,899 females aged ≥ 60 years. …”
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Citywide park renovations and changes in perceived stress: a quasi-experimental study among low-income communities in New York City by Rachel L. Thompson, Katarzyna E. Wyka, Kelly R. Evenson, Lorna E. Thorpe, Glen D. Johnson, Brian T. Pavilonis, Terry T.-K. Huang

“…Methods Pre- and post-renovation data on the Perceived Stress Scale and park use from 162 adults living near (< 0.3 miles) 31 renovated parks and 151 adults living near 21 sociodemographically matched control parks were analyzed. Linear mixed-effects difference-in-difference (DID) regression measured the association between park renovation and change in perceived stress (post-pre) in the overall sample and stratified by baseline sociodemographics. …”
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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. by Shengxu Li, Jing Hua Zhao, Jian'an Luan, Ulf Ekelund, Robert N Luben, Kay-Tee Khaw, Nicholas J Wareham, Ruth J F Loos

“…<h4>Methods and findings</h4>We genotyped 12 SNPs in obesity-susceptibility loci in a population-based sample of 20,430 individuals (aged 39-79 y) from the European Prospective Investigation of Cancer (EPIC)-Norfolk cohort with an average follow-up period of 3.6 y. …”
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Pregnancy Outcomes in Women Infected With COVID-19: A Retrospective Cohort Study by Maryam Nikpour, Mehdi SepidarKish, Mahboobeh Darzipoor, Mahmoud Sadeghi Haddad Zavareh, Rahele Mehraeein, Zeinab Pahlavan, Fereshteh Behmanesh

“…Modified Poisson regression and mixed linear model were used to assess the adjusted risk ratio (aRR) and adjusted mean difference (aMD) between COVID-19 infection and pregnancy outcomes. …”
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Interactive effect of dietary metabolizable energy levels with amino acid density in male broiler chickens: Carcass yield, nutrient intake, digestibility and excretion by Mehdi Toghyani, Shemil MacElline, Peter H. Selle, Sonia Y. Liu

“…Crude fat digestibility decreased linearly with decreased ME density, while reducing ME density linearly decreased fat, calcium, copper, and manganese excretion (P < 0.01). …”
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Nutrient Density and Microbial Safety of Open-Air-Dried Beef Meat and Its Biochemical and Organ Histopathology Effects in Albino Rats: A Promising Ingredient for Complementary Food... by Kifle Habte, Meseret Azene, Yohannes Chanyalew, Samson Girma, Chala Bashea, Asrat Yehualshet, Getamesay Behailu, Abiy Abebe, Masresha Tessema

“…However, further studies need to be conducted on the sensory acceptability of formulated complementary foods containing dried meat powder; also, clinical trials are aimed at observing the effect of dried meat powder on child linear growth.…”
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Association of physical activity, sedentary behaviour, sleep and myopia in children and adolescents: a systematic review and dose-response meta-analysis by Huimin Ding, Liqun Jiang, Xuanqiao Lin, Chaoying Ye, Buongo Chun

“…In the continuous dose-response meta-analysis, a linear association was observed between PA, ST, and myopia. …”
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Effects of multicomponent exercise intervention on cardiometabolic risk factors in children and young adults with cerebral palsy: a multiple-baseline trial by Tiina Savikangas, Pedro Valadão, Eero A. Haapala, Taija Finni

“…Data were analyzed with independent samples t-tests and linear mixed-effects models adjusted for sex and age. …”
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Association between serum neurofilament light chain levels and chronic kidney disease: a cross-sectional population-based study from the National Health and Nutrition Examination S... by Jian-De Lu, Kaisaierjiang Kadier, Diliyaer Dilixiati, Bingzhang Qiao, Renaguli Nuer, Abudureheman Zebibula, Mulati Rexiati, Kai Li, ShuiXue Li

“…Logistic regression models were used to assess the associations between serum NfL levels and CKD, whereas multivariate linear models were used to investigate the relationships between serum NfL levels and two kidney function indicators, namely, estimated glomerular filtration rate (eGFR) and urinary albumin–creatinine ratio (UACR). …”
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Effectiveness of Allopurinol on Uric Acid and Pediatric Chronic Kidney Disease Severity in the Chronic Kidney Disease in Children Study by Derek K. Ng, Matthew B. Matheson, George J. Schwartz, Katherine E. Kurgansky, Bradley A. Warady, Susan L. Furth

“…Nonparametric tests compared levels before and after initiation and within-person changes. Linear mixed effects models characterized baseline and longitudinal differences between treatment groups. …”
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Is there a relationship between serum uric acid and prostate-specific antigen in middle-aged and elderly Chinese men? by Yan Wang, Xiangyang Zhan, Cheng Ma, Xinyu Zhai, Chuanmin Chu, Guanqun Ju, Mingyue Tan, Jianyi Gu, Dongdong Guo, Dongliang Xu

“…The regression spline showed that the risk of elevated PSA tended to a slow but linear increase for SUA levels greater than about 443 μmol/L (P for non-linearity = 0.431). …”
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Evaluation of an organic diet intervention to reduce pesticide exposure: a repeated measures cross-over study among rural and urban communities in Selangor, Malaysia by Vivien How, Maisarah Nasution Waras, Jamilatul Wahidah Jamal Rodzi, Nurul Afina Ahmad Zamani, Hafizah Rukman

“…Linear mixed-effects models assessed differences across dietary phases, and daily trends illustrated changes over time. …”
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Readiness of health facilities to deliver family planning services and associated factors in urban east-central Uganda by Jacquellyn Nambi Ssanyu, Rornald Muhumuza Kananura, Leif Eriksson, Peter Waiswa, Mats Målqvist, Joan Nakayaga Kalyango

“…Readiness was measured using the Service Availability and Readiness Assessment methodology, and health worker knowledge and biases were assessed through the Situation Analysis approach. Sample weights adjusted for facility and health worker representation, and linear regression examined associations between readiness scores and various factors. …”
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Pharmacogenetic study of antipsychotic–induced lipid and BMI changes in Chinese schizophrenia patients: A Genome-Wide Association Study by Kenneth Chi-Yin Wong, Perry Bok-Man Leung, Benedict Ka-Wa Lee, Zoe Zi-Yu Zheng, Emily Man-Wah Tsang, Meng-Hui Liu, Kelly Wing-Kwan Lee, Shi-Tao Rao, Pak-Chung Sham, Simon Sai-Yu Lui, Hon-Cheong So

“…We analysed the patients’ genotypes (N = 669), lipid profiles, and BMI using 19 316 prescription records and 3 917 to 7 596 metabolic measurements per outcome. Linear mixed models were employed to evaluate seven SGAs’ random effects on metabolic changes for each patient, followed by GWAS and gene set analyses with Bonferroni and FDR correction. …”
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Characterization of Glycoprotein 5-Specific Response in Pigs Vaccinated with Modified Live Porcine Reproductive and Respiratory Syndrome Virus Vaccine Derived from Two Different Li... by Jing Huang, Venkatramana D. Krishna, Igor A. D. Paploski, Kimberly VanderWaal, Declan C. Schroeder, Maxim C.-J. Cheeran

“…Animals were challenged with a heterologous (lineage 1A) strain at 64 days post-vaccination (dpv). Blood samples were collected at various times post-vaccination and challenge. …”
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Comparing Synchronous and Asynchronous Remotely Delivered Lifestyle Interventions: Protocol for a Randomized Noninferiority Trial by Sherry Pagoto, Ran Xu, Richard Bannor, Christie Idiong, Jared Goetz, Denise Fernandes

“…We will model percent weight loss at 6 and 12 months using general linear regression models with the intent-to-treat sample. …”
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Evaluation of serum Cystatin C as a predictor of eGFR in type 2 diabetic patients with nephropathy by Aqsa Fatima, Pooran Mal, Zoheb Rafique Memon, Mukesh Kumar, Haseeb Jameel Memon, Misbah Fatima

“…One-way ANOVA, Pearson correlation test, and Linear regression analysis were done to analyze the data. …”
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Evidence of differences in diurnal electrodermal, temperature and heart rate patterns by mental health status in free-living data by Xin Liu, Nicholas B Allen, Ming-Zher Poh, Daniel McDuff, Isaac Galatzer-Levy, Seamus Thomson, Andrew Barakat, Conor Heneghan, Samy Abdel-Ghaffar, Jacob Sunshine, Lindsey Sunden, John B Hernandez, Allen Jiang, Ari Winbush, Benjamin Nelson

“…We recruited 395 participants who had a Fitbit Sense 2 device with the electrodermal sensor activated. We use a non-linear cosinor fitting method to estimate the difference in mesor, amplitude and phase, between the diurnal rhythms in heart rate (HR), heart rate variability (HRV) root mean square of successive differences, EDA, skin temperature and steps.Findings Subjects who exhibited elevated depressive and anxiety symptoms had higher tonic EDA, skin temperature and heart rate, despite not engaging in greater physical activity, compared with those that were not depressed or anxious. …”
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Staying afloat on a realm of shifting sands: carers navigating palliative care in their rural settings by Bonnie Zhu, Peter Lin, Heidi Bevan, Anne Croker, Karin Fisher

“…Thus, we positioned ourselves to view carers&#039; involvement in palliative care in rural areas as being non-linear, active and involving undetermined paths. Locating our research in the interpretive paradigm, we sought to develop a conceptual framework to inform reflections and discussions to provide meaningful support for carers involved in palliative care in rural areas. …”
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