Strength training for osteoporosis prevention during early menopause (STOP-EM): a pilot study protocol for a single centre randomised waitlisted control trial in Canada by Leigh Gabel, Lauren A Burt, Christina J Alexander, Leah Kaluta, Patrick W Whitman, Emma O Billington

“…Feasibility will be assessed based on a priori criterion for success and secondary outcomes will be assessed via multiple linear regressions. The study will be considered feasible if>50% of interested and eligible participants are recruited, if there is>60% adherence to the two times per week, 9-month exercise intervention and if at least 65% of the sample complete the final study visit. …”
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Atypical maturation of the functional connectome hierarchy in autism by Jong-eun Lee, Sunghun Kim, Shinwon Park, Hyoungshin Choi, Bo-yong Park, Hyunjin Park

“…Limitations The uneven distribution of samples across age groups, particularly in the later stages of development, limited our ability to fully capture developmental trajectories among older individuals. …”
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Estimating social contact rates for the COVID-19 pandemic using Google mobility and pre-pandemic contact surveys by Em Prestige, Pietro Coletti, Jantien Backer, Nicholas G. Davies, W. John Edmunds, Christopher I. Jarvis

“…Across all countries investigated, the linear fitted regression model was the most accurate and the naïve model using mobility alone was the least accurate. …”
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Association between body roundness index and risks of all-cause and cardiovascular mortality in adults with metabolic dysfunction-associated steatotic liver disease: NHANES 1999–20... by Yanshan Yi, Li Yang

“…The restricted cubic spline curves indicated a linear relationship between the BRI and both all-cause and cardiovascular disease mortality (p for non-linearity >0.05).ConclusionIn this nationally representative sample of adults with MASLD from the non-institutionalized civilian population in the United States, the BRI served as an independent predictor of both all-cause and cardiovascular disease mortality. …”
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Effect of Degree of Milling (DOM) on Physicochemical and Nutritional Quality of Selected Rice Variety (BRRI dhan78) by Sharmin Akter, Rokeya Begum, Sharifa Sultana Dipti, Md. Abdul Alim, Somaiya Islam Shuchy, Habibul Bari Shozib, Md. Rakibul Hasan

“…Thiamin content was affected by DOM in a linear fashion, declining from 0.15 mg/100 g to 0.13 mg/100 g as DOM increased. …”
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Seasonal Changes in Body Composition, Jump, Sprint, and Agility Performance Among Elite Female Handball Players by Mima Stanković, Borko Katanić, Karuppasamy Govindasamy, Adela Badau, Dana Badau, Bojan Masanovic, Ivana Bojić

“…Players were tested for height, weight, BMI, body fat and muscle mass percentage, jump performance (CMJ, CMJA, SJ, CMJ right, CMJ left), linear sprint (5 m, 10 m, 20 m), and agility performance (zig-zag and slalom). …”
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral allosteric TYK2 inhibitor ESK‐001 using a randomized, double‐blind, placebo‐controlled study design by Sibel Ucpinar, Joyce K. Kwan, Joshua D. Hoffman, Mera K. Tilley, Jeffrey A. Douglas, Roman G. Rubio, Ruixiao Lu, Philip A. Nunn, Claire L. Langrish

“…Transcriptomic analysis of unstimulated whole blood samples confirmed dose‐dependent inhibition of Type I IFN‐induced genes and SIGLEC1, a novel TYK2‐responsive biomarker. …”
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Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study. by Mark Bi, Wen Hong Linda Kao, Eric Boerwinkle, Ron C Hoogeveen, Laura J Rasmussen-Torvik, Brad C Astor, Kari E North, Josef Coresh, Anna Köttgen

“…<h4>Research design and methods</h4>Race-stratified analyses were conducted among 10,929 white and 3,960 black participants aged 45-64 at baseline assuming an additive genetic model and using linear and logistic regression and Cox proportional hazards models.…”
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Changes in non-communicable diseases, diet and exercise in a rural Bangladesh setting before and after the first wave of COVID-19. by Carina King, Sanjit Kumer Shaha, Joanna Morrison, Naveed Ahmed, Abdul Kuddus, Malini Pires, Tasmin Nahar, Raduan Hossin, Hassan Haghparast-Bidgoli, A K Azad Khan, Justine Davies, Kishwar Azad, Edward Fottrell

“…Differences in NCDs, diet and exercise were compared between surveys using chi2 tests, logistic and linear regression; sub-group analyses by gender, age and socio-economic tertiles were conducted. …”
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Investigating the feasibility and acceptability of the HOLOBalance system compared with standard care in older adults at risk for falls: study protocol for an assessor blinded pilo... by Matthew Liston, Christoph Maurer, Doris-Eva Bamiou, Dimitris Kikidis, Gregory Genna, Dimitris Gatsios, Dimitris Fotiadis, Marousa Pavlou

“…Acceptability and feasibility will be explored using descriptive statistics, and trends for effectiveness will be explored using general linear model analysis of variance.Ethics and dissemination This study has received institutional ethical approvals in Germany (reference: 265/19), Greece (reference: 9769/24-6-2019) and the UK (reference: 19/LO/1908). …”
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Relationship of <i>EDNRA</i> rs6842241 and <i>MRAS</i> rs9818870 polymorphic variants with predisposition to coronary artery disease and their effect on the lipid-lowering effect o... by S. I. Kononov, Yu. E. Azarova, E. Yu. Klyosova, M. A. Bykanova, M. A. Solodilova, A. V. Polonikov

“…The genetic and epidemiological study included DNA samples of 1960 Central Russia residents (1261 patients with CAD and 699 healthy individuals). …”
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Eating disorder symptomatology among transgender and gender-diverse individuals: a cross-sectional study by Sofie Martine Rasmussen, Loa Clausen, Maria L. Pop, Astrid D. Højgaard, Mikkel K. Kjeldsen, Gry Kjaersdam Telléus

“…Fisher’s exact test, two-sample t-test, and linear regression model were conducted for analyses. …”
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Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia by Tiantian Yu, Tiantian Yu, Shan Gao, Fen Jin, Bingbing Yan, Wendong Wang, Zhongmin Wang

“…Lactobacillus iners was both negative to nadB and kynU genes, the predicted abundance of which was significantly higher in the CC group. The linear regression model showed that the combination of the vaginal microbiota and vaginal metabolites has good diagnostic performance for cervical cancer.DiscussionOur results indicated a clear difference in the vaginal microbiota and vaginal metabolites of women with cervical dysplasia. …”
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Trends in the availability of community-based home visiting services for oldest-old in China, 2005–2018 by Yukuan Gao, Ruibo He, Zhong Li, Dongfu Qian, Peiyin Hung, Mingsong Xuan

“…Cochran-Armitage tests were used to test linear trends in the proportions of oldest-old with service availability. …”
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Assessment of Acute Toxicity of Quinazoline Derivative 3-[2-oxo-2-(4-Phenylpiperazine-1-yl)Ethyl]quinazoline-4(3h)-oh Active against Opportunistic Microorganisms by N. M. Gabitova, A. A. Tsibizova, A. A. Ozerov, M. A. Samotrueva

“…All experiments were carried out on non-linear mature female rats with a body weight of 180–190 g. …”
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Histerese das isotermas de sorção da polpa de manga (Mangifera indica L.) variedade manteiga Hysteresis of the sorption isotherms of mango pulp (Mangifera indica L.) manteiga varie... by Camila de S. Paglarini, Fabrício S. da Silva, Alexandre G. Porto, Diego Piasson, Philipe dos Santos

“…Foram analisados seis modelos matemáticos para isotermas de sorção (GAB, BET, Halsey, Henderson-Thompson, Oswin e Luikov) ajustados aos dados experimentais, através de regressão não-linear. A histerese foi calculada pela área compreendida entre as curvas de dessorção e adsorção. …”
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Health-related quality of life association with sociodemographic characteristics among children under-five with Down syndrome in Western Region Secondary Care Hospitals, Saudi Arab... by Shrouq R. Almalki, Amjad W. Alotaibi, Asheqah M. Albalawi, Malak E. Aloufi, Nesrin K. Abd El-Fatah

“…A multivariate linear regression analysis was conducted to examine the association between the TAPQOL scores and sociodemographic characteristics in children under the age of 5 years children with DS. …”
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Blood L‐cystine levels positively related to increased risk of hypertension by Haijun Chen, Yalan Deng, Hailing Zhou, Wenzhong Wu, Jinhua Bao, Deyou Cao, Yuze Li, Yingmei Feng

“…Here, the study evaluated hypertension‐associated metabolites in relation to other MetS components. Fasting plasma samples were collected from 22 hypertensive and 63 normotensive subjects for non‐targeted metabolomics. …”
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Do summaries of evidence enable informed decision-making about COVID-19 and influenza vaccination equitably across more and less disadvantaged groups? Study protocol for a multi-ce... by Felix G Rebitschek, Christin Ellermann, Nicolai Savaskan

“…Secondary outcomes include risk perception, decisional conflict and shared decision-making. We will use linear mixed models to analyse the influence of both individual (eg, education status) and cluster level factors and account for the expected cluster variability in realising usual health communication or the intervention. …”
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Determinants of Moral Courage Including the Role of Workplace Conditions, Grief Support, and Salary Among Surgical Nurses in Jiaxing Tertiary Class A Hospitals: A Cross-Sectional A... by Cheng HY, Pu FY, Li XP, Wu LF

“…Participants were required to respond to validated scales measuring moral courage, perceptions of workplace conditions, and grief support. Multiple linear regression analysis was conducted to identify factors associated with moral courage.Results: The mean moral courage was assessed by Chinese version of the Nurses’ Moral Courage Scale (NMCS) with average score of 80.04 ± 14.28 (maximum possible score = 105). …”
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