Bringing bioinformatics to schools with the 4273pi project. by Stevie A Bain, Heleen Plaisier, Felicity Anderson, Nicola Cook, Kathryn Crouch, Thomas R Meagher, Michael G Ritchie, Edward W J Wallace, Daniel Barker

“…At secondary school level, computing is often taught in isolation from other sciences, and its importance in biological research is not fully realised, leaving pupils unprepared for the computational component of Higher Education and, subsequently, research in the life sciences. The 4273pi Bioinformatics at School project (https://4273pi.org) aims to address this issue by designing and delivering curriculum-linked, hands-on bioinformatics workshops for secondary school biology pupils, with an emphasis on equitable access. …”
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Et la forêt brûla sous nos pieds by Arthur Guérin-Turcq, Caroline Paulus, Antonin Renard

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Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project by Teresa Martín, Catarina Guimarães, Cristina Esquinas, Maria Torres-Duran, Alice M. Turner, Hanan Tanash, Carlota Rodríguez-García, Angelo Corsico, José Luis López-Campos, Eva Bartošovská, Jens-Ulrik Stæhr Jensen, José María Hernández-Pérez, Maria Sucena, Marc Miravitlles

“…Method Demographic, clinical, functional, and quality of life (QoL) parameters were assessed to compare the PI*SS characteristics with the PI*SZ and PI*ZZ controls. …”
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Regulating the PI3K and AMPK pathway: the secret of 1-deoxynojirimycin's success in alleviating chronic diseases by Chengwei Yu, Qirui Hu

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RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Osamu Yamanoshita, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Yoshiyuki Kawamoto, Masashi Kato

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Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway by Qiaoli Chen MS, Quanxiang Hao MBBS, Yanping Yang MBBS, Limei Li PhD, Danping Li MS, Ran Zhao MS, Wanqi Wei MBBS, Lixian Deng MBBS, Jiaming Su MBBS, Ziyuan Liang MBBS, Shiyue Tang MS, Yaomin Lu MBBS, Yushan Liang PhD, Zhe Zhang PhD, Xiaoying Zhou PhD, Xue Xiao PhD, Ping Li PhD, Yi Huang PhD, Weilin Zhao PhD

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How to Report Pesticide Misuse in Florida by Frederick M. Fishel

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How to Report Pesticide Misuse in Florida by Frederick M. Fishel

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Toxicity of Tomato and Bell Pepper Insecticides/Miticides to Beneficial Insects by Mark A. Mossler

“…This document is PI-90, one of a series of the Agronomy Department, UF/IFAS Extension. …”
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Toxicity of Tomato and Bell Pepper Insecticides/Miticides to Beneficial Insects by Mark A. Mossler

“…This document is PI-90, one of a series of the Agronomy Department, UF/IFAS Extension. …”
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HTR1D regulates the PI3K/Akt signaling pathway to impact hepatocellular carcinoma development and resistance to sorafenib by Yingai Zhang, Yuting Zhang, Shuai Zhou, Mujeeb Ur Rehman, Fankai Lin, Jianquan Zhang, Hailong Zhou

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Spinal Involvement of TRPV1 and PI3K/AKT/mTOR Pathway During Chronic Postoperative Pain in Mice by Gabriela Xavier Santos, Tayllon dos Anjos-Garcia, Ana Carolina de Jesus Vieira, Giovane Galdino

“…TRPV1 and PI3K/AKT/mTOR protein levels were evaluated by Western blotting. …”
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Alleviation of DSS-induced colitis by Meconopsis polysaccharides correlated with reduced PI3K/AKT signaling and gut microbiome diversity by Jun Dai, Weidong Wang, Fangfang He, Yujuan Wang, Denglang Zou

“…IntroductionInflammatory bowel disease (IBD) is a recurrent gastrointestinal disorder that significantly impacts patients’ quality of life globally. This study focuses on the polysaccharides (MP) extracted from Meconopsis integrifolia, to investigate its role in alleviating DSS (dextran sulfate sodium)-induced colitis in mice.MethodsThe study commenced with a comprehensive chemical characterization of Meconopsis polysaccharides. …”
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Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells by Ju-Young Kim, Ho Kim, Kyoungho Suk, Won-Ha Lee

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Value contribution of leniolisib in the Treatment of Activated PI3Kδ syndrome (APDS) in Spain using Multi-Criteria Decision Analysis (MCDA) by María Reyes Abad, Carmen Alerany, Luis Ignacio Gonzalez, Olaf Neth, Concepción Payares-Herrera, Carlos Rodríguez-Gallego, Jose Luis Trillo, Kirsten H. Herrmann, Raquel Figueiredo, Alicia Gil

“…Background: Activated phosphoinositide 3-kinase (PI3K) δ Syndrome (APDS) is an ultra-rare, potentially life-threatening disease that lacks approved treatments in Spain. …”
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Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway by Li-juan Du, Bing Pang, Yu-meng Tan, Ya-nan Yang, Mei-zhen Zhang, Qing Pang, Min Sun, Qing Ni

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<i>Endarachne binghamiae</i> Extract Ameliorates Inflammatory Responses in Macrophages Through Regulation of MAPK, NF-kB and PI3K/AKT Pathways, and Prevents Acute Lung Injury in Mi... by Sang-Hoon Lee, Sang-Seop Lee, Ga-Young Lee, Seung-Yun Han, Dong-Sub Kim, Bong-Ho Lee, Yung-Choon Yoo

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The PI4K2A gene positively regulates lipid synthesis in bovine mammary epithelial cells and attenuates the inhibitory effect of t10,c12-CLA on lipid synthesis by Tong Mu, Honghong Hu, Xiaofang Feng, Chuanchuan Wang, Juan Zhang, Zhihong Sun, Yaling Gu

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Real-life outcome after failure to venetoclax and hypomethylating-based therapy for acute myeloid leukemia by Carlos Jiménez-Vicente, Iago Arribas, Helena Pomares, Guillermo Ramil, Sandra Castaño-Diez, Amanda Isabel Pérez-Valencia, Antonella Luciana Sturla, Mònica López-Guerra, Alexandra Martinez-Roca, Inés Zugasti, Francesca Guijarro, Albert Cortés-Bullich, Beatriz Merchán, Ana Triguero, Inés Monge, Albert Tuca, Guadalupe Oñate, Ana Garrido, Jorge Sierra, Montserrat Arnan, Jordi Esteve, Marina Díaz-Beyá, Spanish CETLAM Group

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Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway by Xiaolong Liu, Xuran Li, Guangyuan Wu, Pengfei Qi, Yanyan Zhang, Zhiyu Liu, Xinyue Li, Yu Yu, Xiangmei Ye, Yang Li, Dongguang Yang, Yueqiu Teng, Ce Shi, Xin Jin, Sen Qi, Yuting Liu, Shudan Wang, Ying Liu, Fenglin Cao, Qingran Kong, Zhenkun Wang, Hong Zhang

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