A large elevation in 15N/14N of collagenous amino acids: an insight from starvation experiments of marine organisms by Hyuntae Choi, Yuko Takizawa, Nayeon Park, Yoshito Chikaraishi

“…We thus demonstrate that the consumption of collagen in organisms under starvation shows a unique elevation pattern in the δ15NAA value, which is consistent with the observation that collagen is degraded non-quantitatively by the collagenase reaction, whereas muscle is degraded quantitatively by the chaperone-mediated autophagy. …”
Get full text

Exploring drug utilization patterns, healthcare resource utilization, and epidemiology of rheumatoid arthritis in Colombia: a retrospective claims database study by Daniel G. Fernández-Ávila, Monica Betancur, Amira Kronfly, Edwin Jáuregui

“…Results Overall, 327,430 unique patients with RA between 2017 and 2022 were included in the analysis, comprising 94,093 incident cases and 722,569 prevalent cases. …”
Get full text

Mental health in public safety personnel with workplace injuries requiring surgery: a longitudinal population-wide administrative data study in Manitoba, Canada by Tracie O Afifi, Jitender Sareen, Dan Chateau, Alyson Mahar, Jordan Nantais, James Bolton, Allen Kraut, Sarvesh Logsetty, Thomas Turgeon, Brenda Comaskey, Justin Gawaziuk, Rae Spiwak, Lauren Burton, Anthony Wightman, Jai Sareen, Natalie Mota

“…After adjusting, there were no significant differences in rates between the two cohorts; however, the significant group × care interaction term for depression suggests a greater risk for PSP compared with GenPop over time.Conclusions Our findings indicate that, compared with a matched cohort, PSP have an increased risk of depression from the pre-injury to post-injury period following a traumatic physical workplace injury. PSP have a unique mental health trajectory following workplace injury that should be considered when developing rehabilitation strategies for this important population.…”
Get full text

Costs of Potential Medication Wastage Due to Switching Treatment Among People With Multiple Sclerosis by Darin T. Okuda, Achal Patel, Robert Schuldt, Ibraheem Abioye, Nicole G. Bonine

“…PwMS were required to have 12 months of continuous eligibility for the entire year and a claim for at least 2 unique DMTs during the same calendar year. The PMW cohort was defined as those who had an aggregate overlap in days’ supply across DMT switches within the year; those in the non-PMW cohort did not. …”
Get full text

THE IMPACT OF FIRM CHARACTERISTICS ON ACCRUALS AND REAL EARNINGS MANGEMENT OF LISTED MANUFACTURING FIRMS IN NIGERIA by Aisha Chado Muhammad

“…The results indicated; firm size has a consistent negative impact on both AEM and REM, with statistically significant results indicating that larger firms may face unique challenges related to financial reporting quality. …”
Get full text

Genetic trends and common BRCA1/2 pathogenic sequence variants in black African and Indian breast cancer patients presenting at Inkosi Albert Luthuli Central Hospital, KwaZulu-Nata... by M Makhetha, C Aldous, N Chabilal

“…This study highlights unique genetic trends for SA populations and the need for more inclusive targeted tests that are optimal for these populations. …”
Get full text

Effects of Marketing Strategies on the Performance of Tourism and Hospitality Enterprises in Uganda: Case Study of Bwindi Impenetrable National Park. by Asiimwe, Dennis

“…There is a need to clearly communicate the unique features and experiences that set the tourism destination, hotel, or service apart from competitors.…”
Get full text

Brand Association and Competitive advantange in alcoholic beer products in Kabale District, Uganda. by Moses, Agaba

“…This study focuses on Resource Based View a model that provides a framework for identifying unique set of resources and this perspective shifts the approach of assessing competitive advantage from the external to the internal environment that is the resource power. …”
Get full text

Mchan Go Wa Utenzi Wa Mw Anakupona Ka Tika Ukuzaji Na Uendelezaji Wa Lugha Ya Kiswahili Miongoni Mwa Vijana Wa Leo Nchini Uganda. by Kobusingye, Eudia

“…Utenzi wa mwanakupona ni utenzi ambao umekuwa unarejelewa na wasomi au hata na jamii nzima kwa haja ya kurekebisha nidhamu za kijamii au hata na utunzi wa ndoa za kawaida, Lugha ya kiswahili chini Uganda. Lengo kuu katika utafiti huu lilikuwa ni kuchunguza mchango wa utenzi wa mwanakupona katika ukuzaji na uendelezaji wa lugha ya Kiswahili miongoni mwa VIJana wa leo nchini Uganda…”
Get full text

Çin Siyasi Düşüncesi ve Siyasi Tarihi Bağlamında Çinli Siyasi Elitler by Tuğrul Keskin

“…Its comparative approach to Turkish modernization adds a unique perspective, revealing common patterns in elite behavior during political transformation. …”
Get full text

The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy by Huihui Guo, Hongsheng Xie, Yuanyuan Huang, Junxiang Jia, Xiangfei Kong, Qingliang Yang, Shun Gai, Wenjun Li, Lu Bai, Lingli Zhang, Xiaoxiao Chen, Zhicang Ye, Hangbo Ye, Linyao Zhao, Yifang Xu, Yong Du, Xiuzhen Zhang, Miaomiao Chen, Xiaomai Zhou, Robert Y. Zhao

“…Exploration of new small-molecule toxins with unique antitumor and toxicity profiles is crucial. …”
Get full text

Building evidence for indoor tanning as a behavioral addiction: concerns, problems, and change perceptions are associated with addictive symptoms by Allison Leip, Carolyn J. Heckman, Jerod L. Stapleton

“…Conclusions Our findings provide unique evidence for tanning as a behavioral addiction by demonstrating an association between tanning behavioral addiction symptoms with skin cancer concerns, tanning-related problems, and unsuccessful attempts to change. …”
Get full text

Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…Abstract Double negative T (DNT) cells are a unique subset of CD3 + TCRαβ + T lymphocytes that lack CD4, CD8, or NK1.1 expression and constitute 3–5% of the total T cell population in C57BL/6 mice. …”
Get full text

Advancing the Indian cattle pangenome: characterizing non-reference sequences in Bos indicus by Sarwar Azam, Abhisek Sahu, Naveen Kumar Pandey, Mahesh Neupane, Curtis P Van Tassell, Benjamin D Rosen, Ravi Kumar Gandham, Subha Narayan Rath, Subeer S Majumdar

“…A confident set of 6,844 Non-reference Unique Insertions (NUIs) spanning 7.57 Mb was identified through both methods, representing the pangenome of Indian Bos indicus breeds. …”
Get full text

Using the WHO building blocks to examine cross-border public health surveillance in MENA by Laura Buback, Shayanne Martin, Esbeydy Pardo, Farah Massoud, Jesus Formigo, Atousa Bonyani, Noha H. Farag, Zayid K. Almayahi, Kenta Ishii, Susie Welty, Dana Schneider

“…Due to the high levels of mobility and political instability in the Middle East and North Africa (MENA) region, unique challenges arise in cross-border health surveillance. …”
Get full text

Computational analysis of heat transfer and fluid flow characteristics in a diamond microchannel heat sink with orthogonal ribs by Liang Du, Wenbo Hu, Ningkang Deng, Zhaoyang Zhang, Hongxing Wang

“…When the rib width is 0.4, the performance evaluation coefficient reaches 1.92. Therefore, the unique rib arrangement design of the orthogonal rib microchannel heat sink not only optimizes fluid flow and enhances heat transfer capacity but also effectively addresses the heat dissipation challenges of electronic devices. …”
Get full text

TOOLS OF INTERCULTURAL COMMUNICATION IN INTERNATIONAL BUSINESS: A POSTCOLONIAL APPROACH by Eldar Veremchuk, Hennadii Vasylchuk

“…While the former seeks to disguise the colonial influence on business, the progressive branding strategy seeks to promote national and cultural identity by using nationally themed brand names, deleting colonial semantics in naming, and emphasising uniqueness and identity through the use of cultural symbols and motifs. …”
Get full text

First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan by Khalid Salman, Sittna Hayder El Nagar, Abdel Rahim M. El Hussein, Mohammed A. El Hussein, Hadi M. Yassine, Hebah A. Al Khatib, Mashael Ali Al- Badr, Ibrahim Farah, Khalid A. Enan

“…Phylogenetic analysis revealed two distinct Sudanese clusters: one (50 % of sequences) formed a unique clade with low similarity to existing genotypes, while the other (50 %) closely resembled genotype 1 A sequences from Iraq, Iran, and Tanzania. …”
Get full text

Advances and trends of modern and contemporary research on the geology of coal-measure minerals in China by Yong QIN

“…Advances Based on textual research and the analysis of logical relations, this study generalized the advances in research on the geology of CMMs in China into four aspects. (1) Increasingly improved geological theory system of CMMs: China’s classic theoretical system of coal field geology was formed in the second half of the 20th century, and the geological theory system focusing on coals, coal-measure gas, and coal-measure critical metals has been gradually developed since the 21st century. (2) Research on the origin and genesis of coals, advancing the international coal geology: The advancements include the development of the new coal metamorphism theory, the discovery of the world's youngest soft lignite, the reveal of late-stage coalification jumps, the establishment of the ordinary organic petrology, and the comprehensive ascertainment of the formation and evolutionary mechanisms of coals. (3) The unique CMM accumulation, distribution, and metallogenic theory: The specific outcomes include the establishment of multiple sedimentary and structural coal-controlling patterns, the reveal of the fundamental framework of coal accumulation in sea areas, the identification of deposits of various coal-measure critical metals, and the determination of the division schemes for coal-controlling geotectonic units and the metallogenic zones of coal-measure critical metals, and the development of a geological theory system for coalbed methane. (4) Significant achievements in the geological surveys and assessment of special coal resources: Specifically, the methodological system for the geological prediction and assessment of special coal types and high-quality, eco-friendly, and clean coal resources has been developed, the methodological system for the resource potential assessment of tar-rich coals and underground coal gasification has been formed, and the coal resources for related purposes have been preliminarily investigated. …”
Get full text

Comparative analysis of chloroplast genomes reveals molecular evolution and phylogenetic relationships within the Papilionoideae of Fabaceae by Qian Qin, Yanjing Dong, Jialong Chen, Bo Wang, Yuxin Peng, XinPeng Zhang, Xiaoyun Wang, Jinxiang Zeng, Guoyue Zhong, Shouwen Zhang, Xiaolang Du

“…The lengths of the cpDNAs of 18 species range from 121,190 bp to 158,539 bp, and they contain between 107 and 112 unique genes. Five species, namely Desmodium elegans and Indigofera bracteata, exhibit a typical quadripartite structure, while thirteen species from genera such as Astragalus (Ast.), Hedysarum (Hed.), and Caragana (Car.) are grouped within the Inverted Repeat-Lacking Clade (IRLC). …”
Get full text