Comparative the effect of bisphenol A and bisphenol S on the development and spectral sensitivity of cone photoreceptors in zebrafish larvae (Danio rerio) by Liguo Qiu, Peng Yu, Qiang Li, Cuiping Wen, Haiyang Wang, Dongying Zhao, Tianyu Zhang, Chenghui Wang, Lixia Liu, Dongxue Li, Shiyong Wen, Yinghui Sun

“…The results indicated that BPA (10 and 100 μg/L) caused the abnormal proliferation (increased number of cone cells), morphological abnormalities (increased height of cone cells), mosaic pattern disorder, and depressed expression of key genes related to the photo-transduction pathway, and impaired the light perception ability of both red and UV cones ultimately. Similar to the BPA exposure group, BPS (1, 10, and 100 μg/L) exposure resulted in structural damage and mosaic arrays disorder of red and UV cone photoreceptors. …”
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Analysis of Risk Factors for Postoperative Progressive Segment Degeneration at the Decompression and Non-decompression Segments after Minimally Invasive Lumbar Decompression Surger... by Hasibullah Habibi, Hiromitsu Toyoda, Hidetomi Terai, Kentaro Yamada, Minori Kato, Akinobu Suzuki, Shinji Takahashi, Koji Tamai, Masayoshi Iwamae, Yuta Sawada, Yuto Kobayashi, Yuki Okamura, Hiroaki Nakamura

“…A logistic regression model identified that Cobb angle 10° (OR 2.53, 95% CI 1.50-4.24), spondylolisthesis 3 mm (OR 4.447, 95% CI 2.06-9.58), and level of segments were more likely to have PSD at the non-decompression level; additionally, lateral listhesis 3 mm (OR 2.91, 95% CI 1.08-7.81) was more likely to have PSD in the decompression segments. …”
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Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study by Gaoyang Li, Shrikant S. Kolan, Franco Grimolizzi, Joseph Sexton, Giulia Malachin, Guro Goll, Tore K. Kvien, Tore K. Kvien, Nina Paulshus Sundlisæter, Manuela Zucknick, Siri Lillegraven, Espen A. Haavardsholm, Espen A. Haavardsholm, Bjørn Steen Skålhegg

“…Despite methotrexate being the cornerstone of early RA treatment, a significant proportion of patients fail to achieve remission. This study aims to predict 6-month non-remission in 222 disease-modifying anti-rheumatic drug (DMARD)-naïve RA patients initiating methotrexate monotherapy, using baseline patient characteristics from the ARCTIC trial.MethodsMachine learning models were developed utilizing twenty-one baseline demographic, clinical and laboratory features to predict non-remission according to ACR/EULAR Boolean, SDAI and CDAI criteria. …”
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Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s dise... by Anett Futácsi, Anett Futácsi, Anett Futácsi, Kitti Rusznák, Kitti Rusznák, Gergely Szarka, Gergely Szarka, Gergely Szarka, Béla Völgyi, Béla Völgyi, Ove Wiborg, Boldizsár Czéh, Boldizsár Czéh, Boldizsár Czéh

“…BackgroundAnimal models of Alzheimer’s disease (AD) are essential tools for investigating disease pathophysiology and conducting preclinical drug testing. …”
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Deep Learning-Based Feature Extraction Technique for Single Document Summarization Using Hybrid Optimization Technique by Jyotirmayee Rautaray, Sangram Panigrahi, Ajit Kumar Nayak, Premananda Sahu, Kaushik Mishra

“…However, traditional approaches that rely on directly extracting words often lead to redundancies and fail to establish a strong connection between the summary and the original document. …”
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Hypofractionation or other modifications of standard fractionation may improve radiation’s ability to promote immune responses to tumors. Other novel delivery options may also affect immune responses, including T-cell activation and tumor-antigen presentation changes. …”
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Best practice mechanisms for biodiversity conservation law and policy by Callum Brockett, Katie Woolaston, Felicity Deane, Fran Humphries, Ethan Kumar, Amanda Kennedy, Justine Bell-James

“…While there have been some success stories, overall, these laws and policies are routinely failing. Extinction rates continue to climb. However, the law is necessary to regulate the human-environment interactions that form the basis of the drivers of extinction and biodiversity loss, including land-clearing, the discharge of greenhouse gases and the introduction of invasive species. …”
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Application of different edge detection methods for faults identification in Anza Basin, Kenya by Gege Li, Qing Chen, Bingqiang Yuan, Xianfeng Tan, Hao Chen, Xiaoyu Huang, Lang Pan

“…However, the traditional potential field boundary identification method has limited ability to detect the boundaries of buried deep geological bodies. …”
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Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females by Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan Xu, Taylor Smiley, Pingwen Xu, Lulu Chen, Tianshu Zeng, Yanlin He, Chunmei Wang

“…Conclusion: Our results support that the thermosensing ability and estrogenic effects in ERαPOA neurons are regulated by reproductive experience, altering thermal preference.…”
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Study on seismic performance of high-strength steel earthquake-resilient beam-column joint with double damage elements by Hongchao Guo, Dongdong Zheng, Jing Lu, Xudong Zhou, Wenqi Wang, Yunhe Liu

“…The influence of the length lb of the energy dissipation section in the middle of the flange cover plate, the height hs of the stiffening rib, the length lc of the cantilever beam, and the cutting angle αa of the butterfly damper on the joint performance was studied. …”

An assessment of breast cancer HER2, ER, and PR expressions based on mammography using deep learning with convolutional neural networks by Shun Zeng, Hongyu Chen, Rui Jing, Wenzhuo Yang, Ligong He, Tianle Zou, Peng Liu, Bo Liang, Dan Shi, Wenhao Wu, Qiusheng Lin, Zhenyu Ma, Jinhui Zha, Yonghao Zhong, Xianbin Zhang, Guangrui Shao, Peng Gong

“…Area under receiver operating characteristic curve (AUC), accuracy (ACC), and F1-score were calculated to assess the ability of the model to predict each receptor. For comparison we also developed original ResNet-18 without attention module and VGG-19 with and without attention module. …”
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Improving drug repositioning with negative data labeling using large language models by Milan Picard, Mickael Leclercq, Antoine Bodein, Marie Pier Scott-Boyer, Olivier Perin, Arnaud Droit

“…Supervised machine learning is commonly used to score drug candidates but is hindered by the lack of reliable negative data—drugs that fail due to inefficacy or toxicity— which is difficult to access, lowering their prediction accuracy and generalization. …”
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Retrieval of Land Surface Temperature From Passive Microwave Observations Using CatBoost-Based Adaptive Feature Selection by Yang Dai, Yingbao Yang, Xin Pan, Penghua Hu, Xiangjin Meng, Fanggang Li, Zhenwei Wang

“…Passive microwave (PMW) remote sensing is increasingly employed for generating seamless all-weather land surface temperature (LST) data due to its ability to penetrate cloud cover and capture the actual surface conditions underneath. …”
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Fine-tuning GBS data with comparison of reference and mock genome approaches for advancing genomic selection in less studied farmed species by Daniel Fischer, Miika Tapio, Oliver Bitz, Terhi Iso-Touru, Antti Kause, Ilma Tapio

“…Abstract Background Diversifying animal cultivation demands efficient genotyping for enabling genomic selection, but non-model species lack efficient genotyping solutions. …”
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A Real-Time Human Pose Measurement System for Human-In-The-Loop Dynamic Simulators by Nicola Giulietti, Davide Todesca, Marco Carnevale, Hermes Giberti

“…The possibility of achieving real-time evaluation of human pose enables the ability to control robotic platforms based on user’s pose (or even on user’s inertial properties) in Human-In-The-Loop simulators, for sports and rehabilitation as an example. …”
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First-year Class Instills Confidence in Nontechnical Skills for Collegiate Success by Anna Levina, Katy Guthrie, Leah Cook, Marvin Pritts

“…Universities are encouraging academic units to offer introductory courses that include content to help new students adapt and adjust to college life, deal with stress, and plan for future careers. …”
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Correlation between hemoglobin, albumin, lymphocyte, and platelet score and short-term mortality in critically ill patients by Chong Zhang, Wenjin Peng, Meng Ning, Weiru Liang, Bin Su, Tingting Guo, Kun Hu, Wei Su, Yi Chen, Yingwu Liu

“…Additionally, the HALP score improved the predictive ability of the SOFA score (∆Area under curve: 0.009, p < 0.001). …”
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The Impacts of Revenue Sharing on The Development of Buhoma Community in Kanungu District. by Kato, Jacob

“…However it was recommended that there was a need for conserving institutions to be transparent and accountable and fight other hardships that clients may be facing if they are to design effective interventions before the situation fails out. This can enhance revenue acquisition increase performance of employees since transparency and accountability smoothens the performance of any institution yet a National Park is an institution in itself.…”
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Women’s recommendations: vacuum extraction or caesarean section for prolonged second stage of labour, a prospective cohort study in Uganda by Barbara, Nolens, Thomas, van den Akker, John, Lule, Sulphine, Twinomuhangi, Roosmalen, Jos van, Josaphat, Byamugisha

“…Main reasons to opt for CS were having experienced CS without problems, CS presumed as being safer for the neonate, CS being the only option the woman was aware of, as well as the concern that vacuum extraction would fail. …”
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A Nomogram for Predicting Overall Survival in Primary Central Nervous System Lymphoma: A Retrospective Study by Ling Y, Miao X, Zhou X, Ma J, Lin Z, Li Q, Zhang M, Ma Y, Chen B

“…Additionally, Kaplan-Meier survival curves were plotted to show the stratification ability of the risk groups.Results: Eastern Cooperative Oncology Group performance status (ECOG-PS), albumin, and two inflammatory biomarkers D-Dimer, and neutrophil-to-lymphocyte ratio (NLR)—were independent predictors of inferior OS. …”
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