Cortical representation of novel tool use: Understanding the neural basis of mechanical problem solving by Clara Seifert, Thabea Kampe, Cilia Jäger, Jennifer Randerath, Afra Wohlschläger, Joachim Hermsdörfer

“…Introduction: Using tools effectively is a fundamental human ability. Besides the proper recall of semantic knowledge, the application of mechanical problem solving strategies allows one to execute tool-related tasks properly. …”
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Effects of Celery Seed Extracts on Some Haematological and Biochemical Parameters in Albino Rats Treated with Gentamicin by Tavga Ismael Mustafa, Zhakaw Khudir Abdullah, Nazar Mohammed Shareef Mahmood, Shorish Mustafa Abdullah Gorony, Kurdo Bapir Chato, Ranjbar Muksy Mohammed Shareef

“…Thirty-two male rats were weighing 300-400 gm carried out for the present research, they controlled environmentally. Animals were divided equally and randomly into four groups each of which contained eight rats. …”
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Clinical Benefits of Parasternal Block with Multihole Catheters when Inserted before Sternotomy by Vedat Eljezi, Crispin Jallas, Bruno Pereira, Melanie Chasteloux, Christian Dualé, Lionel Camilleri

“…Results: The treatment failed in 11 patients and was considered effective in 15 patients. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…An important cytotoxic impact of amyloidogenic prefibrillar LC oligomers on cardiomyocytes is by now established in isolated rodent cardiomyocytes, simple animal models, or cardiomyocyte-like cell lines. However, the response of human cardiomyocytes to this pathogenic condition is currently unknown. …”
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High-resolution manometry in clinical practice: analysis of esophageal motor function according to Chicago classification by O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“….: change of intrabolus pressure at disorders of esophagogastric junction (EGj) outflow, hypercontractile esophagus, fragmented contractions and weak or failed peristalsis, distal esophageal spasm. Assessment of the type of achalasia subtypes has significant impact on the patients’ treatment choice. …”
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Qualitative focus group study investigating experiences of accessing and engaging with social care services: perspectives of carers from diverse ethnic groups caring for stroke sur... by Geoffrey Cloud, Nan Greenwood, Jess Holley, Theresa Ellmers, Gill Mein

“…Carers from all ethnic groups, but especially those from black and minority ethnic groups frequently fail to access support services, making understanding their experiences important. …”
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Influence of COVID-19 Lockdown on Self-Efficacy in Endodontics among Dental Students by Jelena Vidas Hrstić, Ema Paljević, Ivana Brekalo Pršo, Ivana Vidović Zdrilić, Luka Šimunović, Elvis Božac, Romana Peršić Bukmir

“…It means that individuals who receive verbal encouragement affirming their abilities to succeed in specific tasks are more likely to exert increased efforts and maintain persistence.…”
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A synergistic effect of secondhand smoke with vitamin D deficiency on cognitive impairment in older adults: a cross sectional study by Yan Li, Qianqian Shen, Chengyu Chen, Xueru Yin, Xinru Wang, Xiyue Yang, Xueqian Zhang, Lei Chen, Jian Xu, Guifang Gong

“…The possible synergistic effect of SHS with VDD on cognitive impairment was evaluated by using a multivariable logistic regression model.ResultsVDD was independently associated with risk of low the Digit Symbol Substitution Test (DSST) scores, increased by nearly 60% [< 34, adjusted odds ratio (aOR) = 1.62, 95% CI: 1.03 ~ 2.53]. Although it only had an association with cognitive impairment indicated by DSST and the Animal Fluency test (AFT) in the crude model, SHS exposure showed significant synergistic effects with VDD on DSST (aOR: 3.03, 95% CI: 1.57 ~ 5.83, Pinteraction = 0.001) and AFT (aOR: 2.40, 95% CI: 1.34 ~ 4.29, Pinteraction = 0.003), respectively, after adjusting for the possible confounders. …”
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Conceptual model of sustainable development of pedagogical staff competences in quality assurance of higher education by Andrii Biloshchytskyi, Andrii Biloshchytskyi, Oleksandr Kuchanskyi, Oleksandr Kuchanskyi, Oleksandr Kuchanskyi, Yurii Andrashko, Aidos Mukhatayev, Khanat Kassenov

“…In order to reduce the risks of failing to pass the course, some participants of the competence project proposed to form a pool of potential project participants. …”
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Sexual distress among men with cancer – a cross-sectional study by Jonas Nahavandipour, Christoffer Johansen, Annamaria Giraldi, Bolette Skjøft Rafn, Annika von Heymann

“…However, many studies investigating sexual impairments fail to consider whether such impairments are perceived as distressing, i.e. create sexual distress. …”
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Particle Filtration Efficiency, Breathability, and Reusability of Common Masks by Heikki Junninen, Nieves Maria Flores March, Marko Vana, Kalju Tamme, Helina Lipp, Sander Mirme, Siim Pikker, Tareq Hussein, Markku Kulmala

“…Abstract The Filtration efficiency (FE) and breathability were evaluated for commonly used masks (total of 350 of commercial and home-made) before and after disinfection by one of three options: washing machine (60°C, 90 minutes), boiling in water (5 minutes), or holding in hot water (decreasing temperature from 90°C to 80°C, 5 minutes). …”
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Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster by Yi Pan, Ke Fan, Linhao Zong, Yantao Luo, Xin Ni, Dong Chen, Jinjun Qian, Fei Ma, Jie Cheng, Miao Guan

“…Although the evidence for Cd-induced reproductive toxicity is well established, it remains elusive on the intricate dose-response relationship and underlying molecular mechanisms, especially for transgenerational toxicity in animals. Here, we employed fruit fly (Drosophila melanogaster) as a model organism to examine the reproductive performance across five generations by parental exposure to varying concentrations of Cd (5, 50, and 500 μM). …”
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Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

“…Plant-based food consumption correlates with increased telomere length and reduced phenotypic age, while animal-based food intake is linked to adverse aging effects. …”
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Enhancing feature selection for multi-pose facial expression recognition using a hybrid of quantum inspired firefly algorithm and artificial bee colony algorithm by Mu Panliang, Sanjay Madaan, Siddiq Ahmed Babikir Ali, Gowrishankar J., Ali Khatibi, Anas Ratib Alsoud, Vikas Mittal, Lalit Kumar, A. Johnson Santhosh

“…The evaluated features are utilized for classifying face expressions by utilizing the deep neural network model, ResNet-50. …”
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Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit by Talib Al Harthy, Michael R Miller, Orlando daSilva, Soume Bhattacharya

“…Success rates were 91% in SurfCath™ and 93% in BLEScath™ (P\> 0.994). Failed attempts were lower in SurfCath™ (23%) in comparison to BLEScath™ (33%), but the difference was not statistically significant (P=0.708). …”
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Yiqi Fumai Lyophilized injection protects cardiac contractility in a rat model of heart failure with reduced ejection fraction by modulating SERCA2 by Yongwei Nie, Lu Chen, Yanxin Zhang, Yuqing Yao, Zizhuo Xue, Na Guo, Meixiu Wan, Zhi Li, Chunhua Liu, Dekun Li, Aichun Ju

“…Background: Yiqi Fumai Lyophilized Injection (YQFM) is a plant-derived preparation that shows protective effects against cardiac dysfunction in both human and animal models. In heart failure (HF), proteins involved in Ca2+ regulation, such as sarcoplasmic/endoplasmic reticulum Ca2+ transporting protein 2 (SERCA2) and cardiac ryanodine receptor 2 (RyR2), are dysfunctional. …”
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Municipios “libres de eucaliptos”: análisis de los actores políticos locales en Galicia by Diego Cidrás

“…En particular, las argumentaciones de contenido económico y social, más recurridas por parte de los ediles, adoptan un mayor protagonismo frente a las ecológicas y territoriales, minoritarias, y generan un aislamiento partidario que motiva la falta de consenso. …”
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Prognostics optical coherence tomography biomarker in macular oedema secondary to retinal vein occlusion by Andrea R. Silitonga, Hanna T.H. Silitonga, Rova Virgana, Iwan Sovani, Arief Kartasasmita, Erwin Iskandar, Grimaldi Ihsan, Made Indra

“…Several OCT biomarkers such as disorganisation of the retinal inner layer (DRIL) and disruption of the ellipsoid zone (EZ) and the external limiting membrane (ELM) were identified but did not show significant associations with final BCVA after multivariate analysis. …”
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Silent magnetic resonance angiography diagnostic value of intracranial unruptured aneurysms by Bin Lv, Tingyang Zhang, Ning Wang, Lu Liu, Mingyu Li, Meng Li, Mingguang Sun, Xiao Zang, Xinfeng Liu, Rongju Zhang, Xiangyu Cao, Zhihua Du, Jun Wang, Jinhao Lyu, Xueyang Wang, Qi Duan, Fangfang Guo, Xin Lou, Chenglin Tian

“…Abstract Silent magnetic resonance angiography (S-MRA) is primarily utilized to assess the blood flow in aneurysms and parent vessels of treated intracranial aneurysms. …”
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Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations by Lucas Tricoli, Sunetra Sase, Julia L. Hacker, Vi Pham, Maxwell Chappell, Laura Breda, Stephanie N. Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Matthew Hogenauer, Aoife Roche, John Everett, Frederic Bushman, Peter Kurre, Rebecca Ahrens-Nicklas, Laura A. Adang, Adeline L. Vanderver, Stefano Rivella

“…Our top-performing vector (EA1) showed at least 4× more ARSA activity than the currently US and European Union (EU)-approved vector and a superior ability to secrete vesicle-associated ARSA, a critical modality to transfer functional enzymes from microglia to oligodendrocytes. …”
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