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Expert consensus on orthodontic treatment of protrusive facial deformities
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Nonacademic predictors of China medical licensing examination
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RUNX2 enhances bladder cancer progression by promoting glutamine metabolism
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Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis
Published 2025-01-01“…BackgroundPeriplanta americana extract (PAE), a traditional Chinese medicine (TCM) from Shen Nong Ben Cao Jing, has been used to treat ulcerative colitis (UC), various types of wounds and ulcers, infantile malnutrition, palpitation, asthma, and so on. …”
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Role and Effective Therapeutic Target of Gut Microbiota in Heart Failure
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Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation
Published 2025-02-01“…Xiaoxu Fan,1 Shuangqiao Liu,1 Jing Yu,2 Jian Hua,1 Yingtong Feng,1 Zhen Wang,1 Yiwei Shen,1 Wei Lan,2 Jingxia Wang1 1School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2School of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi, People’s Republic of ChinaCorrespondence: Jingxia Wang, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China, Email 601435@bucm.edu.cn Wei Lan, School of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi, People’s Republic of China, Email lanwei516@sina.comBackground: Diabetic liver injury (DLI) is a common complication of diabetes mellitus (DM), which seriously endangers the health of diabetic patients. …”
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Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment
Published 2025-01-01“…Yunheng Liu,1,* Longqing Si,1,* Yuxuan Jiang,1,* Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. …”
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Fu Tu Sheng Jin Rehabilitation Formula Mitigate Airway Inflammation, Mucus Secretion and Immune Dysfunction Induced by SARS-CoV-2 Spike Protein
Published 2025-01-01“…Bo-Han Wang,1,* Ke-Yao Yu,2,* Xiao-Na Zhang,3,* Xian-Hong Sun,2 Ling-Ling Tang,4 Xiao-Lu Shi2 1NanJing JiangNing Hospital of Chinese Medicine/Affiliated jiangning Hospital of Chinese Medicine, China Pharmaceutical University, Nanjing, Jiangsu, 210029, People’s Republic of China; 2Affiliated Hospital of Nanjing University of Chinese Medicine/ Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, People’s Republic of China; 3Nanjing Hospital of Chinese Medicine, Nanjing, Jiangsu, 210029, People’s Republic of China; 4School of Chinese Medicine & School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Lu Shi; Ling-Ling Tang, Email fsyy00721@njucm.edu.cn; 290602@njucm.edu.cnObjective: To evaluate the effects of Fu Tu Sheng Jin Rehabilitation Formula (FTSJRF) on airway inflammation, mucus secretion, and immunoreaction in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-induced mouse model.Methods: Forty-two mice were randomly divided into seven groups: normal, D1, D3, D10, D10H, D10M and D10L, according to the days of modeling and different dosages of FTSJRF. …”
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Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis
Published 2025-01-01“…CuiCui Gong,1– 3 Junyang Chen,2 Pingjin Zou,2 Zengyi Fang,2 Li Quan,1– 3 Jing Wang,2,4 Jie Yin,2,5 Bing Lin,1 Jinyi Lang,1– 5 Meihua Chen2,3 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610032, People’s Republic of China; 2Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610041, People’s Republic of China; 3Institute of Integrated Traditional Chinese and Western Medicine Cancer Research, Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, People’s Republic of China; 4Department of Oncology, School of Clinical Medicine, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 5School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 611731, People’s Republic of ChinaCorrespondence: Jinyi Lang, School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, People’s Republic of China, Email langjy610@163.com Meihua Chen, Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610041, People’s Republic of China, Email chenmeihua@scszlyy.org.cnPurpose: Radiation-induced pulmonary fibrosis (RIPF) is a serious complication of radiotherapy that lacks effective treatment options. …”
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Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study
Published 2025-02-01“…Zhen Gao,1,* Meng-Jie Cui,2,* Hai-Jun Wang,2 Jing Zhang,3 Cheng Xu,4 Lai-Xi Ji2 1Experimental Management Center, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 2Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 3Acupuncture and Moxibustion Department II, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 4Radiology Department, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lai-Xi Ji, Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Jinci Road Section 1, No. 89, Taiyuan, Shanxi, 030024, People’s Republic of China, Email jlx@sxtcm.edu.cnPurpose: The objective of this research is to delve into the central pathological mechanisms involved in the transformation from acute to chronic pain.Patients and Methods: This study enrolled 86 individuals with acute neck pain and 89 with chronic neck pain. …”
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