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Microtubule inhibition as a proposed mechanism for the anthelmintic effect of phytochemicals isolated from Cicerbita alpina
Published 2025-02-01“…Additionally, the BuOH fraction was non-cytotoxic to human cell-lines. Subsequent FCC and SEC derived subfractions were submitted to the anthelmintic assay workflow and the enriched subfractions B1 and E3.8, phytochemically assigned as 11-β,13-dihydrolactucin and luteolin, demonstrated bioactivity against the embryo phenotype (B1 | 58% ED | c = 1.8 µM and E3.8 | 46% ED | c = 1.7 µM) within range of the flubendazole control. …”
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch...
Published 2025-03-01“…Summary: Background: How cardiovascular diseases (CVD) predispose to a higher risk of fragility fractures is not well understood. …”
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Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus
Published 2025-02-01“…In cSLE, RD SNVs were observed in the C1S, DDX58, IFIH1, IKZF1, RNASEH2A and C8A genes. …”
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Clinical and microbiological analysis of risk factors for breakthrough bloodstream infection during Tigecycline Therapy
Published 2025-02-01“…Of the K. pneumoniae and A. baumannii isolates for which tigecycline susceptibility results were available, 50% and 23%, respectively, were tigecycline-resistant (MIC > 2 mg/L). Intraabdominal (33.9%), catheter-related (30.4%), and hepatobiliary (19.1%) infections were the main sources of breakthrough BSI. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial
Published 2018-07-01“…Preliminary investigations have shown that decoding motor volition using myoelectric pattern recognition, while providing real-time feedback via virtual and augmented reality (VR-AR), facilitates phantom motor execution (PME) and reduces PLP. …”
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Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions.
Published 2025-01-01“…We tested this hypothesis using 4C-Seq (circular chromosome confirmation capture-sequencing) and show that HPV18 establishment causes a loss of long-range chromosomal interactions between the CADM1 transcriptional start site and the upstream transcriptional enhancer. …”
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A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula
Published 2025-02-01“…However, similar data in cartilaginous fishes, the sister group to all other extant jawed vertebrates, are still lacking. Here, we present a single-nucleus RNA sequencing atlas of the postnatal retina of the catshark Scyliorhinus canicula, consisting of the expression profiles for 17,438 individual cells from three female, juvenile catshark specimens. …”
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Multi-dimensional outcomes following extracorporeal cardiopulmonary resuscitation
Published 2025-03-01“…Background: Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or “ECMELLA” (VA-ECMO plus Impella®) may improve short-term survival and neurological outcomes in selected patients with refractory cardiac arrest. …”
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FOTODEGRADAÇÃO NO CLIMA SEMIÁRIDO EM FILMES DE POLI(BUTILENO ADIPATO-CO-TEREFTALATO) PUROS E ADITIVADOS COM ÓLEO ESSENCIAL DE CRAVO DA ÍNDIA (Syzygium aromaticum (L.) Merr.)
Published 2025-02-01“…Overall, the results indicate a comparable degradation pattern between pure PBAT samples and additives with 5% OEC in a natural atmosphere environment of a semi-arid climate.…”
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Supervised Injecting Room Cohort Study (SIRX): study protocol
Published 2025-02-01“…The two cohorts are: (1) participants drawn from the existing Melbourne Injecting Drug User Cohort Study (SuperMIX; established in 2008–ongoing) through which participants consent to annual behavioural surveys (including serological testing for HIV and hepatitis B and C viruses) and linkage to administrative data; and (2) the SIRX-Registration Cohort (SIRX-R; established in 2024) comprising registered MSIR clients who consent to a baseline behavioural survey and administrative data linkage including the frequency of SIF use, and the uptake of on-site services. …”
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Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study
Published 2025-02-01“…JCO Global Oncology…”
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A NOVEL DATASET FOR VIETNAMESE NEW YEAR FOOD CLASSIFICATION
Published 2024-08-01“…Tạp chí Khoa học Đại học Đà Lạt…”
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Health and social care use, costs, and satisfaction among key workers accessing Resilience Hub support during the COVID-19 pandemic
Published 2025-02-01“…BMC Health Services Research…”
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