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621
Causal relationship between hormone levels and lung cancer: a Mendelian randomization study
Published 2025-02-01“…We explored the causal relationship between 15 hormones and three subtypes of lung cancer. The inverse variance weighted (IVW) method was used as the primary analysis, while MR-Egger, weighted median, weighted mode, and simple median were applied as supplementary methods. …”
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622
The causal associations of 25(OH)D and its metabolites with oropharyngeal cancer risk: a Mendelian randomization study
Published 2025-07-01“…The primary analytical method for two-sample MR analysis was inverse-variance weighting (IVW); supplemental analyses (weighted median [WM], MR–Egger) were also conducted. …”
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623
Association of decreased glomerular filtration rate with renal hemodynamic disorders and inflammatory biomarkers in patients with medically-controlled hypertension of high cardiova...
Published 2021-10-01“…The results of correlation analysis were used to determine the determinants of GFR decline. …”
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624
A radiomics-based interpretable model integrating delayed-phase CT and clinical features for predicting the pathological grade of appendiceal pseudomyxoma peritonei
Published 2025-07-01“…DCA confirmed greater clinical utility across most threshold probabilities, with favorable Brier scores (training:0.124; testing:0.142) indicating excellent calibration. SHAP analysis identified the top predictive features: wavelet-LHH_glcm_InverseVariance (radiomics), original_shape_Elongation (radiomics), and CA-199 (clinical). …”
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625
Lipid-lowering drug targets associated with risk of respiratory disease: a Mendelian randomization study
Published 2025-02-01“…Three statistical approaches were employed for MR analysis: inverse variance weighting (IVW), MR-Egger, and weighted median. …”
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626
The study of factors affecting acute odontogenic osteomyelitis prevalence among Zaporozhye citizens
Published 2014-08-01“…Recording and processing the following criteria of data: diagnosis, age, sex, cause of the disease, the patient's place of residence, length of hospital stay, employed patients, therapy. …”
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627
M-CSF Protects Against Ulcerative Colitis via Aconitate: Mendelian Randomization and Experimental Evidence
Published 2025-07-01“…In addition, MR analysis showed M-CSF had an inverse correlation with the disease onset of UC (OR: 0.31, 95% CI: 0.15– 0.80, p = 0.002, IVW beta all = − 1.16). …”
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628
A physiologically-based pharmacokinetic model for the antibiotic ertapenem
Published 2015-09-01“…Parameters in the model were estimated using a least squares inverse problem formulation with published data for blood concentrations of ertapenem for normal height, normal weight males. …”
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629
Thyroid dysfunction in MASLD: Results of a nationwide study
Published 2025-05-01Get full text
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630
The newly proposed dietary index for gut microbiota and its association with the risk of nonalcoholic fatty liver disease: the mediating role of body mass index
Published 2025-06-01“…Methods In this cross-sectional study, we utilized data from the NHANES 2009–2018. Multivariable logistic regression, restricted cubic spline curves (RCS), subgroup analysis, and mediation analysis were used to evaluate the association between DI-GM and the risk of NAFLD. …”
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631
Brief Report: Exercise and Blood Pressure in Older Adults—An Updated Look
Published 2018-01-01“…Measurements. The recently developed inverse heterogeneity model (IVhet) was used to pool findings and the Doi plot was used to examine for small-study effects. …”
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632
Lipid have a direct effect on multiple myeloma: a Mendelian randomization study
Published 2024-06-01“…This study aims to explore this relationship using Mendelian randomization (MR) analysis.MethodsLiposome-associated genetic instrumental variables (IVs) were identified from plasma lipidomics data of 7,174 Finnish individuals within a Genome-Wide Association Study (GWAS) pooled database. …”
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633
Assessing Causality Between Plasma Brain‐Derived Neurotrophic Factor With Major Depression Disorder: A Bidirectional Mendelian Randomization Study
Published 2025-03-01“…Multiple MR methods were applied to ensure a robust analysis. Results The inverse variance weighted (IVW) method revealed no significant association between plasma BDNF levels and the risk of developing MDD (IVW odds ratio [OR] = 1.00, 95% confidence interval [CI] = 0.99–1.01, p = 0.769). …”
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634
Association between thyroid dysfunction and diabetic retinopathy: a two-sample bidirectional Mendelian randomization study
Published 2024-12-01“…In the reverse MR analysis, DR was found to be associated with an elevated risk of developing hyperthyroidism and hypothyroidism (IVW: OR = 1.56, 95% CI 1.38–1.76, P < 0.001; OR = 1.41, 95% CI 1.25–1.59, P < 0.001). …”
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635
Towards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.
Published 2025-01-01“…Biophysical models offer the possibility to anticipate system behavior and provide insights into physiological functions, advancements which are comparatively and notably nascent when it comes to pulmonary mechanics research. In this context, an Inverse Finite Element Analysis (IFEA) pipeline is developed to construct the first continuously ventilated three-dimensional structurally representative pulmonary model informed by both organ- and tissue-level breathing experiments from a cadaveric human lung. …”
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636
The effect of work-family conflict on staff nurses’ job performance: the mediating role of emotional intelligence
Published 2025-05-01“…Three validated instruments: the Work-Family Conflict Scale, the Six-Dimension Scale of Nursing Performance, and the Wong and Law Emotional Intelligence Scale were utilized for data collection. Descriptive and inferential statistics and path analysis were used to analyze the data. …”
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637
Association between the gut microbiota and diabetic nephropathy: a two-sample Mendelian randomization study
Published 2024-12-01“…We aimed to explore any potential causal links between the GM composition and the risk of developing DN. A meta-analysis conducted by the MiBioGen consortium of the largest genome-wide association study (GWAS) provided aggregated data on the GM. …”
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638
Tilting Pad Thrust Bearing Fault Diagnosis Based on Acoustic Emission Signal and Modified Multi-Feature Fusion Convolutional Neural Network
Published 2025-02-01“…Learning was then conducted on the signal fused with multiple features using the inverse-add module and spanning convolution. Next, a comparative analysis was carried out among the CNN1D, ResNet, and DFCNN models, and the MMFCNN model proposed in this study. …”
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639
Predictive reward-prediction errors of climbing fiber inputs integrate modular reinforcement learning with supervised learning.
Published 2025-03-01“…Through tensor component analysis of two-photon Ca2+ imaging data from more than 6,000 Purkinje cells, we found that climbing fiber inputs of the two distinct components, which were specifically activated during Go and No-go cues in the learning process, showed an inverse relationship with predictive reward-prediction errors. …”
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640
Sexual function, depression, and quality of life in patients with irritable bowel syndrome
Published 2025-07-01Get full text
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