Causal relationship between immune mediators and parkinson’s disease: A Mendelian randomization analysis by Ruqing Qiu, Yana Su, Lin Pan, Kangli Fan, Zhihui Sun, Yue Liang, Xiaoyue Lin, Ying Zhang

“…Additionally, we utilized PD risk data from a large meta-analysis of GWAS, which included 33,674 PD cases and 449,056 controls. …”
Get full text

Metabolism-Mediated FGF5 Association with Stroke: Based on Mendelian Randomization and Bioinformatics Analysis by Xu C, Xu Y, Gao L, Wang M, Wang G, Wang G

“…The role of fibroblast growth factor 5 (FGF5) in the occurrence and development of stroke remains unclear. We used bidirectional Mendelian randomization (MR) analysis to evaluate the mediating role of metabolites and causal association between inflammatory factors and stroke.Methods: We analyzed the stroke dataset from the FinnGen database (v11) (cases: 43,132; Control: 297,867). …”
Get full text

Association of sleep traits with risk of adverse pregnancy outcomes: a Mendelian randomisation analysis by Shuyi Shao, Zhenhong Shuai, Chunrong Qin, Jiejie Shao, Chunqin Chen, Minmin Song, Xuemei Li, Huanqiang Zhao

“…The main analysis employed inverse-variance-weighted MR, with sensitivity analyses conducted to mitigate potential pleiotropy-induced biases. …”
Get full text

GPR Diffraction Separation by Incorporating Multilevel Wavelet Transform and Multiple Singular Spectrum Analysis by Haolin Wang, Honghua Wang, Zhiyang Hou, Fei Zhou

“…By leveraging amplitude differences between reflected and diffracted signals in Ground Penetrating Radar (GPR) data, multiple singular spectrum analysis (MSSA) is considered an attractive approach to separate diffraction, which has identified great potential in their detectability of small-scale geological structures. …”
Get full text

Association analysis of maternal exposure to air pollution during pregnancy and offspring asthma incidence by Lili Bao, Yuan Liu, Yuhong Zhang, Qian Qian, Yifen Wang, Wei Li, Yanyan Yu

Get full text

Theoretical Study and Application of Rate Transient Analysis on Complex Fractured-Caved Carbonate Reservoirs by Qingyan Yu, Qi Wang, Pengcheng Liu, Jing Zhang, Qi Zhang, Xiaojuan Deng, Kai Feng

“…Carbonate reservoirs are mainly fractured-caved reservoirs with very well-developed dissolved pores, fractures, and caves. They have strong heterogeneity with various types of reservoir pore spaces. …”
Get full text

Hilbert–Huang transform based pupil changes analysis for concentration assessment in skilled mowing by Bo Wu, Yuan Wu, Ran Dong, Kiminori Sato, Soichiro Ikuno, Shoji Nishimura, Qun Jin

“…The results of the study can provide useful insights for training new lawn mowers, and the relevant data can be used as data accumulation for the development of future fall detection systems.…”
Get full text

Intrauterine metformin exposure and adiposity outcomes in children: a systematic review and meta-analysis by George Tomlinson, Jill Hamilton, Kellie E Murphy, Jennifer Fu, Najla Tabbara, Denice S Feig

“…Objective The study aims to assess the effect of intrauterine metformin exposure on offspring adiposity measures in childhood.Design Systematic review and meta-analysis.Data sources Medline, Embase and Cochrane Central were searched from inception to 4 October 2024.Eligibility criteria for selecting studies Follow-up studies of randomised-controlled trials and observational studies involving metformin use in pregnancy for any insulin-resistant maternal condition were included.Data extraction and synthesis Two reviewers independently extracted data and completed risk-of-bias assessments using either Cochrane Risk-Of-Bias tool V.2 or Risk of Bias in Non-Randomised Studies of Exposure depending on study design. …”
Get full text

The Study of Spatial Heterogeneity and Interregional Relations in the Processes of Attracting Banking Capital to the Russian Economy by I. V. Naumov, S. S. Krasnykh

“…Anselin, regression analysis using panel data, testing cause-and- effect relationships using the Granger method, formation of a matrix of functional dependencies between regional systems. …”
Get full text

Large-scale biosynthetic analysis of human microbiomes reveals diverse protective ribosomal peptides by Jian Zhang, Dengwei Zhang, Yi Xu, Junliang Zhang, Runze Liu, Ying Gao, Yuqi Shi, Peiyan Cai, Zheng Zhong, Beibei He, Xuechen Li, Hongwei Zhou, Muxuan Chen, Yong-Xin Li

“…These RiPPs are distributed across various body sites but show a specific enrichment in the gut and oral microbiome. Big data omics analysis reveals that numerous RiPP families are inversely related to various diseases, suggesting their potential protective effects on health. …”
Get full text

Investigating the Causal Relationship between Environmental Sustainability, Economic Development, and Life Expectancy in Iran in Different Time Horizons: Wavelet Transform and Four... by Abolghasem Golkhandan, Sahebe Mohamadian Mansour

“…It investigated the causal relationship between the inverse of load capacity factor (index of environmental degradation), per capita income (index of economic growth and development), and life expectancy (index of health output) in different time horizons from 1961 to 2022 using the time series data of Iran. …”
Get full text

Causal relationship between multiple types of food intake and myopia: a Mendelian randomization study by Sha-Sha Zhang, Jiao-Jiao Liang, Yun Feng, Xia Hong, Yi-Jia Zhao, Ling Chen, Ping Lin

“…AIM: To investigate the causal relationship between dietary intake and myopia using Mendelian randomization (MR) analysis. METHODS: Genome-wide association study (GWAS) data from the IEU Open GWAS database were utilized to examine associations between myopia and various dietary factors. …”
Get full text

Phenological growth and development stages of asparagus pea (Tetragonolobus purpureus Moench.) under different sowing patterns in the conditions of the Right-Bank Forest-Steppe of... by I. Bobos, O. Komar, I. Fedosiy, A. Matvienko

“…The study synthesised data on the application of phenological models to develop adaptive production technologies for asparagus pea, enabling the regulation of phenological phase progression while considering the unique characteristics of the cultivar and regional conditions. …”
Get full text

Causal relationship between gout and Alzheimer's disease： a two-sample Mendelian randomization analysis by Kong Chuijia, Zhang Ying, Tan Zhenkun, Ping Junjiao, Zhang Haibo, Zhang Jie, Luo Jiali, Liu Xinxia

“…Previous studies have suggested that gout may reduce the risk of developing AD， but the causal relationship between the two still requires further research.ObjectiveTo investigate the potential causal relationship between gout and AD through a two-sample Mendelian randomization （MR） analysis， so as to provide references for the prevention and treatment of AD.MethodsData from Genome-Wide Association Studies （GWAS） extracted in 2024 were analyzed， using pooled data on gout （6 810 cases in the case group and 477 788 cases in the control group） published by UK Biobank in 2021 as the exposure variable， and data on AD （3 899 cases in the case group and 214 893 cases in the control group） published by FinnGen in the same year as the outcome variable. …”
Get full text

Analysis of Visitor Perceptions of Malang City Thematic Parks using a Text Mining Approach by Nur Izza Vania, Aisyah Larasati, Yuh-Wen Chen, Nikmatus Sholikha

“…These methods effectively process large volumes of unstructured data to reveal meaningful insights. The analysis focused on three parks with the highest number of reviews: Alun-Alun Kota Malang (945 reviews), Taman Merjosari (552 reviews), and Alun-Alun Tugu (462 reviews). …”
Get full text

Assessing Biocultural Diversity Across Scales Using Ecological Indicators by Bryam Mateus-Aguilar, Andrés Felipe Díaz-Salazar, Federico Andrade-Rivas, Natasha M. Batista, Anaid Cárdenas-Navarrete, Armando Dávila Arenas, Katherine Victoria Hernandez, Guido A. Herrera-R, Kelley E. Langhans, Dallas R. Levey, Andrew Neill, Oliver Nguyen, Natalia Ocampo-Peñuela, Andrés Felipe Suárez-Castro, Felipe Zapata, Alejandra Echeverri

Get full text

Investigating the causal links between inflammatory cytokines and scoliosis through bidirectional Mendelian randomization analysis by Muradil Mardan, Mardan Mamat, Parhat Yasin, Xiaoyu Cai, Huoliang Zheng, Qingyin Xu, Shaokuan Song, Bo Li, Hao Cai, Pengbo Chen, Zeyu Lu, Shahna Omar, Shengdan Jiang, Leisheng Jiang, Xin‐feng Zheng

“…Results Our analysis demonstrated a significant causal association between the cytokine Resistin (RETN) and the development of scoliosis (p = 0.024, OR 95% CI = 1.344 [1.039–1.739]). …”
Get full text

Ulcerative colitis increases the risk of atrioventricular block: evidence from a Mendelian randomized analysis by Wanqiong Shu, Guanghong Huang

“…To ensure the rigor of the analysis results, we selected another set of exposure data sets and conducted the MR verification analysis using the same method. …”
Get full text

Mendelian Randomization Analysis of the Possible Causal Relationships Between Neurodevelopment‐Related Proteins and Bipolar Disorder by Yanyan Li, Qianqian Gui, Shurong Ren, Zhifen Liu, Aixia Zhang, Penghong Liu, Xueping Zhou, Ning Sun, Chunxia Yang

“…In this study, MR was used to assess the causal relationships between neurodevelopment‐related proteins and BD, thereby providing potential evidence for the neurodevelopmental hypothesis of this mental disorder. Methods Leveraging data from large‐scale genome‐wide association studies (GWASs), the associations between six neurodevelopment‐related proteins and BD were analyzed using five MR approaches; namely, inverse‐variance weighted, weighted median, MR–Egger, simple mode, and weighted mode methods. …”
Get full text

THE ROLE OF WHITE BLOOD CELL COUNT IN PERIANAL PATHOLOGIES: A RETROSPECTIVE ANALYSIS OF HEMATOLOGIC MALIGNANCIES by Bedrettin Orhan, Fahir Özkalemkaş, Vildan Özkocaman, Büşra Gürbüz, Tuba Ersal, İbrahim Ethem Pınar, Cumali Yalçın, Ömer Candar, Sinem Çubukçu, Tuba Güllü Koca, Rıdvan Ali

Get full text