Ultrasound for evaluating gastrointestinal symptoms in irritable bowel syndrome patients: A systematic review by Anas Elgenidy, Ramez M. Odat, Mohamed Hesn, Asmaa Abodaif, Mohamed S. Elgendy, Mohammad Alzu'bi, Abdelrahman R. Youssef, Shady Sapoor, Mahmoud Mohamed AlSanafini, Moustafa Elnewishy, Paula Gamal Wassef

“…We aim to evaluate the utility of ultrasound (US) in diagnosing and monitoring IBS by assessing various aspects such as intestinal motility, gallbladder function, urinary bladder, gastric function, autonomic dysfunction, and vagus nerve assessment. …”
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Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…In addition, a cross-talk proteomic approach was used to identify differentially regulated proteins (DRPs) in the proteome of the human intestinal epithelial cell line (Caco-2) co-cultured with L3 larvae of A. simplex (s. s.) or directly exposed to two concentrations (low or high) of Anis-EVs. …”
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Blood proteome profiling for biomarker discovery in broilers with necrotic enteritis by Svitlana Tretiak, Teresa Mendes Maia, Delphi Van Haver, An Staes, Simon Devos, Tom Rijsselaere, Evy Goossens, Filip Van Immerseel, Francis Impens, Gunther Antonissen

“…The pathophysiology of necrotic enteritis (NE) has been extensively studied. While intestinal changes have been very well documented, data addressing NE-induced alterations in the blood proteome are scant, although these might have merit in diagnostics. …”
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Enhanced anti-infective activities of sinapic acid through nebulization of lyophilized protransferosomes by Hani A. Alhadrami, Hani A. Alhadrami, Amr Gamal, Ngozi Amaeze, Ahmed M. Sayed, Mostafa E. Rateb, Demiana M. Naguib

“…Various formulations were prepared and characterized for entrapment efficiency (EE), release, and size to select the optimized formulation. It was then lyophilized into a powder to be evaluated in vivo for its pharmacokinetic properties.Results and discussionSA exhibited antibacterial and antifungal activity, with SA-protransferosomes showing enhanced effectiveness compared to that of pure SA and approaching the efficacy of positive controls. …”
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Reconstruction Methods and Complications of Esophagogastrostomy and Jejunal Interposition in Proximal Gastrectomy for Gastric Cancer: A Meta-Analysis by Nan Du, Pei Wu, Pengliang Wang, Yuwei Du, Kai Li, Zhenning Wang, Huimian Xu, Zhi Zhu

“…Results. Eight studies were selected, and 496 patients were included. EG group benefits were 44.81 min shorter operating time (P<0.001), 56.58 mL less blood loss (P=0.03), and 7.4 days shorter hospital stay time (P<0.001) than the JI group. …”
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Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis by Xuan Zhao, Xiaolu Ye, Yuting Gu, Yijie Lou, Zhanyi Zhou, Yunxi Ji, Yunxi Ji, Daogun Xu

“…BackgroundInflammatory Bowel Disease (IBD) is a chronic, idiopathic inflammatory disorder of the intestines. Oxymatrine (OMT) is a naturally active substance found in the desiccated roots of Sophora flavescens. …”
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Hypolipidemic Activity of the Polysaccharide L-rhamnopyranosyl-6-O-methyl-galacturonan in Combined Administration with HMG-CoA Reductase and Cholesterol Absorption Inhibitors by E. E. Buyko, V. V. Ivanov, O. A. Kaidash, O. Yu. Rybalkina, E. A. Kiseleva, S. V. Krivoshchekov, T. L. Kiseleva, A. M. Guriev, M. V. Belousov

“…Dyslipidemia treatment in many cases requires carefully selected combination of lipid-lowering drugs including bile acid sequestrants. …”
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Metagenomic signatures of extraintestinal bacterial infection in the febrile term infant gut microbiome by Anna L. DeVeaux, Carla Hall-Moore, Nurmohammad Shaikh, Meghan Wallace, Carey-Ann D. Burnham, David Schnadower, Nathan Kuppermann, Prashant Mahajan, Octavio Ramilo, Phillip I. Tarr, Gautam Dantas, Drew J. Schwartz

“…Using a combination of EBI isolate genomics and fecal metagenomics, we detected an intestinal strain presumptively isogenic to the EBI pathogen (> 99.999% average nucleotide identity) in 63% of infants with EBIs. …”
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Effectiveness of personalized granola tailored to the gut microbiota for improving gut environment and mood states by Hiroyuki Sasaki, Hirofumi Masutomi, Yohsuke Yamauchi, Katsuyuki Ishihara, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda

“…Fecal samples were collected at baseline, week 4, and week 8 for gut microbiota and intestinal metabolite analysis via 16S rRNA gene sequencing and gas chromatography–mass spectrometry. …”
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Infectious Morbidity in Closed Long-Term Care Facilities in the «Pre-COVID Stage» by V. G. Akimkin, N. G. Davydova, S. V. Ugleva, Zh. B. Ponezheva, S. V. Shabalina

“…Out of 16171 initially identified articles, 61 publications were selected after initial analysis.Conclusions. According to various estimates, the leading infectious diseases in CLTFS were: acute respiratory infections, pneumonia, urinary tract infections, skin and mucous infections, acute intestinal infections. …”
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NEW IN THE TREATMENT OF TYPE 2 DIABETES by V. G. Kadzharyan, N. I. Kapshytar

“…Alpha-glucosidase inhibitors (acarbose, miglitol, voglibose) competitively inhibits intestinal enzymes (α-glucosidase). It consequently slows carbohydrate absorption from foods and supply of glucose into the blood. …”
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Electroacupuncture Exerts Anti-Obesity Effects by Affecting the Gut Microbiota and Upregulating Acetic Acid and 5-HT Levels in Obese Rats by Zhang J, Yang C, Xiong J, Qian H, Xie Y, Xie S, Luo Y, Yu J, Yu H, Xu J

“…Therefore, we aimed to explore the mechanism by which electroacupuncture alleviates obesity induced by a high-fat diet (HFD) by modulating the gut microbiota.Methods: Fifty specific pathogen-free Sprague–Dawley (male) rats were obtained, and 44 rats were randomly selected and subjected to an HFD. The remaining six rats were used as controls and subjected to a basic diet. …”
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The correlation between serum adiponectin and hypoxia-inducible factor-1 in patients with diabetic nephropathy by ZHANG Zhi-qin, WEI Mao-bi, WANG Bai-ying, CHEN Wei, WU Xiao-yan

“…Objective To investigate the correlation between adiponectin(ADPN) and hypoxia-inducible factor-1(HIF-1α) in the serum of diabetic nephropathy patients and its clinical significance.Methods A total of 65 diabetic nephropathy(DKD) patients admitted to Central South Hospital of Wuhan University from 2019.8.27 to 2019.12.29 were selected. Diagnostic criteria of diabetic nephropathy referred to Expert Consensus on Prevention and Treatment of Diabetic Nephropathy(2014 edition).The control group(CN) consisted of 23 patients with only oblique hernia or intestinal polyps without other symptoms.The diabetic nephropathy group was divided into macroalbuminuria subgroup(10 patients) and microalbuminuria subgroup(37 patients) according to the urinary protein excretion(UAER).The remaining 18 patients were non-albuminuria.The DKD group meeting the criteria of diabetic retinopathy with any stage of chronic kidney disease was included in the retinopathy group.However,since there was also a retinopathy subgroup in the proteinuria group,the cumulative number of retinopathy subgroup was 26 patients.The standard of the macroalbuminuria subgroup was urinary albumin>300 mg/24 h or(+++)or above,while the standard of the microalbuminuria subgroup was ualbumin <300 mg/24 h or(++)or below.The differences and correlations of serum adiponectin and HIF-1α between the two groups and their subgroups were analyzed to explore their clinical significance.Results Serum adiponectin and HIF-1α levels in the diabetic nephropathy group were higher than those in CN group,and serum adiponectin in the DKD group was 3808 ng/L(3625,4164) vs.CN group 2954 ng/L(2439,3809)(P<0.01);serum HIF-1α in the DKD group was 130.44 ng/L(119.50,143.08) vs.CN group 98.32 ng/L(88.04,117.71)(P<0.01).At the same time,linear regression analysis showed that serum ADPN level was positively correlated with hif-1α,with R correlation coefficient=0.961,slope=26.29,and P<0.01.Moreover,the detection efficiency of serum adiponectin and hif-1 to DKD was 0.747 and 0.776,respectively,and P<0.01.Conclusion Serum adiponectin level is increased and positively correlated with HIF-1α in diabetic nephropathy,and serum adiponectin and HIF-1α may have correlative mechanism worthy of exploration.Serum ADPN may be co-involved in the progression of diabetic nephropathy by relating to hypoxia in the body.…”
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Sodium-dependent phosphate transporter NaPi2b as a candidate for targeted therapy: features of structure, function, and expression by R. G. Kiyamova, R. A. Vlasenkova, L. F. Bulatova

“…The NaPi2b transporter gene (SLC34A2) has a broad expression pattern in healthy tissues, including small intestinal epithelial cells, where NaPi2b plays a major role in the absorption of dietary phosphate. …”
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Prevalence and Molecular Characterization of Cysticercus tenuicollis Isolated from Some Intermediate Host in Kurdistan-Iraq by Abdullah Ahmed Hama, Rostam Hama Zorab, Fatima Mohammed Ali, Awaz M. Salih, Amer Abdullah Hassan

“…Cysticercus tenuicollis (C. tenuicollis) is the larval stage infection of Taenia hydatigena, a common tapeworm of dogs and other Canidae, which has a wide range of intermediate hosts including sheep, goat, cattle, deer, camel, horse, human and other wild ruminants, the disease spreads through a contaminated water, soil and food with feces of infected dogs or other carnivores, T. hydatigena lives in the intestinal of the definitive host (carnivores) and excretes a huge number of eggs with feces daily. …”
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Whole-genome analysis of five Escherichia coli strains isolated from focal duodenal necrosis in laying hens reveals genetic similarities to the E. coli O25:H4 ST131 strain by Yu-Yang Tsai, Julia Ienes Lima, Sonsiray Alvarez Narvaez, Catherine M. Logue

“…ABSTRACT Focal duodenal necrosis (FDN) is an intestinal disease causing significant economic losses in the table-egg industry due to reduced egg production in laying hens. …”
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Evaluation of the Cost-Effectiveness of Vaccination of Children with 5-valent Vaccine against Rotavirus Infection in the Russian Federation by Alla V. Rudakova, Susanna M. Kharit, Aleksandr T. Podkolzin, Aleksandr N. Uskov, Yurii V. Lobzin

“…One of the main causes of the incidence of intestinal infections in children under 5 years infection is rotavirus. …”
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056. Impacted CBD Stones in Ampula Vater Evacuated by Transduodenal Approach in A 48-year-old Patient at Prof. Dr. IGNG Ngoerah Hospital in 2024 by Komang Soni Wicaksana Wijaya, Made Agus Dwianthara Sueta

“…Conclusion: The transduodenal approach to evacuating impacted CBD stones at the Ampulla of Vater is a valuable technique that can yield excellent outcomes in select cases. This case report underscores the importance of a tailored approach based on individual patient anatomy and stone characteristics.…”
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Zingiber striolatum phytochemicals ameliorated hyperglycemia symptoms by modulating gut microbial communities in mice with type 2 diabetes mellitus by Tingting Liu, Xiaodong Ge, Lu Song, Huanhuan Wu, Xue Qian, Bowen Jia, Chao Zhao, Yi Zhuang

“…Predictive analysis of the correlation between gut microbiota and hypoglycemic parameters identified Dubosiella, Bacillus, and Mailhella as potential microbial biomarkers for further investigation into the pathogenesis of T2DM.ConclusionZSE plays a pivotal role in mitigating hyperglycemia in T2DM mice through the modulation of intestinal microbiota communities.…”
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Precision microbiota therapy for IBD: premise and promise by Manabu Nagayama, Lasha Gogokhia, Randy S. Longman

“…Inflammatory Bowel Disease (IBD) is a spectrum of chronic inflammatory diseases of the intestine that includes subtypes of ulcerative colitis (UC) and Crohn’s Disease (CD) and currently has no cure. …”
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