Effectiveness of syndecan-1 as an adjunct diagnostic marker in small bowel injury: a report of two cases by Hideshi Okada, Keiko Suzuki, Fuminori Yamaji, Tetsuya Fukuta, Masahiro Ichihashi, Yosuke Mizuno, Takahito Miyake, Norihide Kanda

“…Surgery was performed, revealing small intestinal injuries. In both patients, a high serum syndecan-1 level in the blood test at admission was a common characteristic.Conclusion Increased serum syndecan-1 level was observed in blood tests during the initial treatment of small intestinal injuries in these patients, suggesting its potential utility in early diagnosis. …”
Get full text

Changes in the Subdoligranulum genus in patients with autoimmune disease: a systematic review and meta-analysis by Lu Shen, Ying Zhao, Shuting Liu, Shangfeng Li, Qian Li, Tao-Hsin Tung, Bo Shen

“…BackgroundAutoimmune diseases have different pathogenic mechanisms but share underlying patterns of gut microbiome perturbation and intestinal barrier dysfunction. Recent evidence suggests that an arthritogenic strain of Subdoligranulum causes a local inflammatory response in the gut. …”
Get full text

Comparative analysis of autodermal graft and polypropylene mesh use in large incisional hernia defects reconstruction by Stojiljković Danilo, Kovačević Predrag, Višnjić Milan, Janković Irena, Stevanović Goran, Stojiljković Predrag, Stojiljković Marija, Trenkić Milan, Golubović Zoran, Ignjatović Nebojša, Dimitrijević Zorica, Kovačević Tatjana, Stošić Biljana, Bagur Nataša

“…For their successful tension-free repair a proper selection of reconstructive material is essential. …”
Get full text

Research on screening key proteins related to the pathogenesis of sepsis associated encephalopathy based on DIA proteomics technology by Wu Shuhui, Hu Hongjie, Lu Yuru, Zhu Wei

“…Key differential proteins were further screened using machine learning models such as Extreme Gradient Boosting （XGBoost） and Least Absolute Shrinkage and Selection Operator （LASSO） regression to construct a nomogram and evaluate its diagnostic performance. …”
Get full text

Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing by Hua Huang, Jiaze Ma, An Kang, Tianwei Guo, Wei Sun, Yan Xu, Lijiang Ji

“…In an animal model, we utilized immunofluorescence and western blotting to validate the expression of these genes in the affected intestinal segments.ResultsOur investigation identified specific monocyte subtypes associated with UC through a comprehensive analysis involving cell communication, Least Absolute Shrinkage and Selection Operator (LASSO), and Support Vector Machine (SVM) methodologies. …”
Get full text

Approaches to discern if microbiome associations reflect causation in metabolic and immune disorders by Marijana Basic, Dominique Dardevet, Peter Michael Abuja, Silvia Bolsega, Stéphanie Bornes, Robert Caesar, Francesco Maria Calabrese, Massimo Collino, Maria De Angelis, Philippe Gérard, Miguel Gueimonde, François Leulier, Eva Untersmayr, Evelien Van Rymenant, Paul De Vos, Isabelle Savary-Auzeloux

“…This transformation is crucial for the efficient translation into clinical application and development of targeted strategies to beneficially modulate the intestinal microbiota. As mechanistic studies are still quite challenging to perform in humans, the causal role of microbiota is frequently evaluated in animal models that need to be appropriately selected. …”
Get full text

Mechanisms by which Porphyromonas gingivalis evades innate immunity. by Kaveh Abdi, Tsute Chen, Brian A Klein, Albert K Tai, Jill Coursen, Xiangdong Liu, Jeff Skinner, Saravanan Periasamy, Youngnim Choi, Benedikt M Kessler, Robert J Palmer, Apostolos Gittis, Polly Matzinger, Margaret J Duncan, Nevil J Singh

“…The oral cavity is home to unique resident microbial communities whose interactions with host immunity are less frequently studied than those of the intestinal microbiome. We examined the stimulatory capacity and the interactions of two oral bacteria, Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum), on Dendritic Cell (DC) activation, comparing them to the effects of the well-studied intestinal microbe Escherichia coli (E. coli). …”
Get full text

Early Life Exposure to Human Milk Oligosaccharides Reduces Allergic Response in a Murine Asthma Model by Tahereh Bozorgmehr, Rozlyn C. T. Boutin, Sarah E. Woodward, Katherine Donald, Jo May Chow, Rachael H. Buck, B. Brett Finlay

“…Studies suggest that early-life gut microbiota composition and intestinal short-chain fatty acids (SCFAs) are linked to future asthma susceptibility. …”
Get full text

Upadacitinib for refractory Behçet’s disease with myelodysplastic syndrome and trisomy 8/9: a case report and mechanistic insights by Yukai Wang, Feng Tian, Hui Li

“…Initiation of upadacitinib (45 mg/day), a selective JAK1 inhibitor, resulted in symptom resolution within one week and complete mucosal healing confirmed by colonoscopy at three months. …”
Get full text

Systematic Review: Adverse Events of Fecal Microbiota Transplantation. by Sinan Wang, Mengque Xu, Weiqiang Wang, Xiaocang Cao, Meiyu Piao, Samiullah Khan, Fang Yan, Hailong Cao, Bangmao Wang

“…<h4>Background</h4>Fecal microbiota transplantation (FMT) is a microbiota-based therapy that shows therapeutic potential in recurrent or refractory Clostridium difficile infections and other intestinal or extra-intestinal disorders. Nonetheless, adverse events (AEs) remain a major challenge in the application of FMT.…”
Get full text

GASTROINTESTINAL PARASITES AND ASSOCIATED GUT PATHOLOGY IN CHICKENS SOLD AT LIVE-BIRD MARKETS IN LAGOS STATE, SOUTHWESTERN NIGERIA by Oluwayomi Oluwatoyin Adeyemi, Emmanuel Taiwo Idowu, Bamidele Akinsanya, Isa Danladi Jatau, Temitope Morenikeji Oladipo

“… Gastrointestinal (GI) parasites compromise intestinal health in poultry, causing impaired nutrient uptake, poor growth rate and reduced productivity. …”
Get full text

Pathophysiological Prerequisites and Therapeutic Potential of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis by D. V. Garbuzenko

“…One of them is the techniques that provide intestinal eubiosis, in particular, through the fecal microbiota transplantation. …”
Get full text

Detection and significance of human epidermal growth factor receptor 2 expression in gastric adenocarcinoma by Sutapa Halder, Debjani Mallick, Priyanka Mondal, Debajyoti Singha Roy, Aniket Halder, Sudipta Chakrabarti

“…All positivity was noted in intestinal type according to Lauren classification (25%) and none in diffuse type. …”
Get full text

Peculiarities of the Provision of Surgical Care for Abdominal Emergencies in Hospitals Remodeled to Provide Medical Care to Patients with COVID-19 From the Perspective of a Systema... by A. M. Karsanov, V. V. Aleksandrov, S. S. Maskin, A. Ya. Korovin, K. I. Popandopulo

“…We found 1 combined (prospective-retrospective) multicenter and 1 retrospective comparative study on the treatment tactics of acute cholecystitis, 1 retrospective multicenter cohort study on acute pancreatitis, 1 retrospective study on acute intestinal obstruction and 2 studies on acute appendicitis, 1 case-control study on gastrointestinal tract and intestinal bleeding (level 3 evidence, level B recommendation).Conclusion. …”
Get full text

Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development by I. V. Mayev, D. N. Andreev, D. V. Rakitina, Yu. P. Baykova

“…Undoubtedly, such model is most likely relevant only for selected part of CD patients, nevertheless for the present moment it is the basic for the further studying of CD etiopathogenesis.…”
Get full text

Effect of Functional Galactooligosaccharide on Metabolism and Antibacterial Activity of Lactiplantibacillus plantarum ZDY2013 by Jinlin LU, Jinmei LI, Jie FENG, Kaisheng SHAO, Hua WEI, Zhihong ZHANG

“…Taken together, the functional GOS could selectively promote the metabolism of L. plantarum ZDY2013 and further inhibit B. cereus HN001 in the co-culture systems and cell model.…”
Get full text

Minimally Invasive Treatment of Sporadic Burkitt’s Lymphoma Causing Ileocaecal Invagination by Paolo Panaccio, Michele Fiordaliso, Domenica Testa, Lorenzo Mazzola, Mariangela Battilana, Roberto Cotellese, Federico Selvaggi

“…We describe a rare case of intestinal obstruction due to sporadic Burkitt’s lymphoma causing ileocaecal invagination explaining our experience Methods. …”
Get full text

Postoperative ileus and associated factors in patients following major abdominal surgery in Ethiopia: a prospective cohort study by Fasika Chanie Animaw, Melash Belachew Asresie, Amanuel Sisay Endeshaw

“…A total of 252 were selected by consecutive sampling techniques and included in the final analysis. …”
Get full text

Effect and mode of action of different doses and sources of zinc in weaning pigs using a meta-analytical and systematic review approach by Diana Luise, Clara Negrini, Federico Correa, Paolo Trevisi

“…The HZn group had higher Escherichia coli (p = 0.04) in the small intestine. The ZnO database confirmed that Zn doses between 600 and 1600 ppm had comparable results for intestinal function and growth performance to pharmacological doses of Zn. …”
Get full text

Impact of viral disease hypophagia on pig jejunal function and integrity. by Emma T Helm, Shelby M Curry, Carson M De Mille, Wesley P Schweer, Eric R Burrough, Nicholas K Gabler

“…Further, long term adaptation to PRRSV challenge and caloric restriction does reduce intestinal transepithelial resistance but does not appear to reduce the integrity of tight junction protein complexes.…”
Get full text