Antihyperlipidemic, Antihyperglycemic, and Liver Function Protection of Olea europaea var. Meski Stone and Seed Extracts: LC-ESI-HRMS-Based Composition Analysis by Amina Ben Saad, Mohamed Tiss, Henda Keskes, Anisa Chaari, Maria Eleni Sakavitsi, Khaled Hamden, Maria Halabalaki, Noureddine Allouche

“…Moreover, the MSM extract exhibited a prominent selective inhibitory effect against intestinal lipase and α-amylase activities. The MSM extract was also able to protect the liver-kidney functions efficiently, which was evidenced by biochemicals and histological studies.…”
Get full text

Molecular Diagnosis of Pneumonia Using Multiplex Real-Time PCR Assay RespiFinder® SMART 22 FAST in a Group of Moroccan Infants by Kenza Hattoufi, Houssain Tligui, Majdouline Obtel, Sobha El Ftouh, Aicha Kharbach, Amina Barkat

“…Thus, the early and fast detection of related causative agents is crucial. The use of multiplex real time polymerase chain reaction may help choose an accurate treatment, reduce the overall use of unnecessary antibiotics, preserve intestinal flora, and decrease nosocomial infection by reducing the length of hospitalization.…”
Get full text

Formulation Approaches for Optimizing Omeprazole Stability in Oral Liquid Dosage Forms by Urszula Adamiak-Giera, Michał Gackowski, Damian Malinowski, Tomasz Osmałek, Marta Karaźniewicz-Łada, Anna Machoy-Mokrzyńska, Monika Białecka

“…Release studies were conducted using basket or paddle apparatus under conditions simulating fasted (pH 1.2 and 6.8) and fed (pH 6, 4.5, and 3) gastric and intestinal juices at 37 °C over 120 min. At predetermined intervals, samples were withdrawn and analyzed by a validated HPLC method with UV detection to quantify the released omeprazole. …”
Get full text

The correlation between serum adiponectin and hypoxia-inducible factor-1 in patients with diabetic nephropathy by ZHANG Zhi-qin, WEI Mao-bi, WANG Bai-ying, CHEN Wei, WU Xiao-yan

“…Diagnostic criteria of diabetic nephropathy referred to Expert Consensus on Prevention and Treatment of Diabetic Nephropathy(2014 edition).The control group(CN) consisted of 23 patients with only oblique hernia or intestinal polyps without other symptoms.The diabetic nephropathy group was divided into macroalbuminuria subgroup(10 patients) and microalbuminuria subgroup(37 patients) according to the urinary protein excretion(UAER).The remaining 18 patients were non-albuminuria.The DKD group meeting the criteria of diabetic retinopathy with any stage of chronic kidney disease was included in the retinopathy group.However,since there was also a retinopathy subgroup in the proteinuria group,the cumulative number of retinopathy subgroup was 26 patients.The standard of the macroalbuminuria subgroup was urinary albumin>300 mg/24 h or(+++)or above,while the standard of the microalbuminuria subgroup was ualbumin <300 mg/24 h or(++)or below.The differences and correlations of serum adiponectin and HIF-1α between the two groups and their subgroups were analyzed to explore their clinical significance.Results Serum adiponectin and HIF-1α levels in the diabetic nephropathy group were higher than those in CN group,and serum adiponectin in the DKD group was 3808 ng/L(3625,4164) vs.CN group 2954 ng/L(2439,3809)(P<0.01);serum HIF-1α in the DKD group was 130.44 ng/L(119.50,143.08) vs.CN group 98.32 ng/L(88.04,117.71)(P<0.01).At the same time,linear regression analysis showed that serum ADPN level was positively correlated with hif-1α,with R correlation coefficient=0.961,slope=26.29,and P<0.01.Moreover,the detection efficiency of serum adiponectin and hif-1 to DKD was 0.747 and 0.776,respectively,and P<0.01.Conclusion Serum adiponectin level is increased and positively correlated with HIF-1α in diabetic nephropathy,and serum adiponectin and HIF-1α may have correlative mechanism worthy of exploration.Serum ADPN may be co-involved in the progression of diabetic nephropathy by relating to hypoxia in the body.…”
Get full text

Emergence of extensively drug-resistant Klebsiella pneumoniae from broiler chickens and clinical samples in Egypt by Mohamed E. Enany, Heba S. El-Mahallawy, Wafaa E. I. Mohammed, Wafaa M. M. Hassan, Abdelkarim M. Aboueisha

“…It is present in the intestinal tract of animals and humans, and is considered as a major threat to public health. …”
Get full text

A prospective study on enhanced recovery of Mycobacterium tuberculosis from children’s stool using novel power ultrasound decontamination by Jun-ling Wang, Zhen-jin Zhang, Fang Wang, Ming-kai Chen, Peng Tian, Xin-feng Wang

“…In conclusion, our findings indicate that the PU method is a rapid and effective decontamination method for stool in children, improving the detection of active TB among pediatric populations when compared to the NALC-NaOH method.…”
Get full text

Case Report: Successful treatment of severe Guillain-Barré syndrome with paralytic ileus as a presenting symptom by intensive immunotherapy by Long Luo, Lei Chen, Jun Li, Ye Deng, Caihong Chen, Dan Cheng, Yang Liu, Huaping Zhang, Ling Zhu

“…Involvement of the intestinal autonomic nerves in Guillain-Barré syndrome (GBS) can lead to paralytic ileus, a condition commonly observed in severe cases during later stages of the disease. …”
Get full text

Gut microbiota interplay with autophagy-EMT dynamics in colorectal cancer by Tiziana Vescovo, Giulio Bontempi, Giulio Bontempi, Mohammadreza Bayat, Mohammadreza Bayat, Lucia Piredda, Marco Fidaleo, Marco Fidaleo, Raffaele Strippoli, Raffaele Strippoli, Manuela Antonioli, Manuela Antonioli

“…In contrast, beneficial microorganisms such as Bifidobacterium and Lactobacillus provide protective effects by boosting immune surveillance and supporting the integrity of the intestinal barrier. This review examines the complex connection between gut microbiota and CRC, emphasizing how changes in microbial composition facilitate tumor development and influence treatment outcomes. …”
Get full text

Prediction of the course of antibiotic-associated diarrhea caused by <i>Clostridioides difficile</i> based on clinical and laboratory characteristics of the disease by Konstantin D. Ermolenko, Tatiana V. Potapova, Kseniia V. Silav, Konstantin V. Zhdanov, Dmitry A. Lioznov, Denis A. Gusev

“…CDI was confirmed by detection of toxins A and B of C. difficile in feces using enzyme-linked immunosorbent assay and immunochromatography. …”
Get full text

Surface display of Nocardia seriolae HRP1 on Bacillus subtilis and its application as live vaccine for largemouth bass by Fengli Zhang, Ji-Tong Li, Tengyuan Zhang, Xiao Wang, Yuanyuan Yao, Zhigang Zhou

“…The live bacterial vaccine altered the composition of the intestinal flora, demonstrated a decline in Firmicutes and an increase in Fusobacteria, and a significant decrease in Clostridium replaced by Cetobacterium at the genus level. …”
Get full text

Evaluation of Time to Positivity of Blood Cultures in Pediatric Patients by Gizem Guner Ozenen, Tansu Aydoğan, Zühal Ümit, Nimet Melis Bilen, Irem Ersayoglu, Pınar Yazıcı Özkaya, Miray Karakoyun, Feriha Cilli, Zumrut Sahbudak Bal

“…BACKGROUND: The early detection of causative microorganisms for BSI helps clinicians to initiate appropriate antimicrobials to reduce mortality. …”
Get full text

Peanut thresholds in peanut‐allergic children are related to dietary composition by Daisy Luiten, Maarten Biezeveld, Olga vanDoorn, Hanae Riady, Ming Yang, Femke Bergsma, Atie van derPlas, Kim Brand, Nicolette Arends, Annette deBruin, Jeanne deVries, Tim deMeij, Berber Vlieg‐Boerstra

“…Microbial composition of faeces and saliva were determined by molecular microbiota detection technique. Multivariable linear regression analysis and multiple logistic regression were used to explore the associations, adjusted for energy and senitization. …”
Get full text

Association of miR-149 gene rs2292832 polymorphism with necrotizing enterocolitis in preterm infants by Hong Qiu, Xiaojun Wang, Yanhong Li, Renping Mao, Qin Lv

“…Necrotizing enterocolitis (NEC) is a prevalent and challenging intestinal disease in premature infants, lacking a specific pathogen consistently associated with its occurrence. …”
Get full text

Uncovering SARS-CoV-2 Molecular Epidemiology Across the Pandemic Transition: Insights into Transmission in Clinical and Environmental Samples by Vrushali D. Patil, Rashmi Chowdhary, Anvita Gupta Malhotra, Jitendra Singh, Debasis Biswas, Rajnish Joshi, Jagat Rakesh Kanwar

“…However, ACE2 expression in intestinal cells has sparked worries about possible fecal transfer, particularly in poor-sanitation areas like India. …”
Get full text

Enteromorpha prolifera soluble dietary fiber alleviates ulcerative colitis through restoration of mucosal barrier and gut microbiota homeostasis by Yuan-Yuan Ding, Yuan-Yuan Ding, Xin-Yi Tang, Yu Tian, Feng-Long Zhang, Xiang Ding, Meng-Chun Qi, Wei Dong, Chen-Guang Liu

“…Additionally, EDFM promoted the proliferation of beneficial probiotics (Alloprevotella, Lachnospiraceae_NK4A136_group, and Ruminococcaceae_UCG-014), while inhibiting pathogenic bacteria (Escherichia-Shigella, Parabacteroides, Rikenellaceae_RC9_gut_group, Odoribacter, and [Ruminococcus]_torques_group).ConclusionEDFM supplementation significantly ameliorates UC through dual modulation of gut microbiota and intestinal barrier integrity, indicating its potential as a functional food ingredient for UC prevention and treatment.…”
Get full text

Changes in microbiome composition after fecal microbiota transplantation via oral gavage and magnetic navigation technology-assisted proximal colon/cecum enema in antibiotic knock-... by Xian-Jie Bai, Yu-Chen Mei, Jia-Tong Zhao, Zhi-Ren Chen, Chen-Xi Yang, Xiao-Juan Dong, Jia-Wei Yu, Lin-Biao Xiang, Er-Zheng Zhou, Yong Chen, Jia-Yi Hao, Zhi-Jie Zhang, Yu-Xuan Liuyang, Lu Ren, Ying-Min Yao, Lei Zhang, Yi Lv, Qiang Lu

“…FMT by enema was superior to gavage in maintaining the integrity of the rat intestinal barrier, as assessed by an elevation in the density of goblet cells and increased expression of mucin-2. …”
Get full text

Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles. by Sol Vendrell-Fernández, Beatriz Beamud, Yasmina Abou Haydar, Jorge Am de Sousa, Julien Burlaud-Gaillard, Etienne Kornobis, Bertrand Raynal, Joelle Vinh, David Bikard, Jean-Marc Ghigo

“…Advances in metagenomics have led to the identification of new intestinal temperate bacteriophages. However, their experimental characterization remains challenging due to a limited understanding of their lysogenic-lytic cycle and the common lack of plaque formation in vitro. …”
Get full text

Effect of parasites on the of digestive system in Iraqi bulbul Pycnonotus lecuotis mesoptamiae by Baghdad Science Journal

“…Chronic inflammations and rottenness has been detected in the glandular stomach and the musculae stomach.The villi of the small intestine of the infected birds appeared to have abnormal shapes, cracked and with lost details compared to the control, beside the hypertrophy of the enteric glandular layer. …”
Get full text

Differentiation of mtDNA Methylation in Tissues of Ridgetail White Prawn, <i>Exopalaemon carinicauda</i> by Muchen Jiang, Jiayi Gao, Xinyu Zhou, Hao Zhong, Sichen Zhang, Jing Xu, Fei Yu, Xiaofang Lai, Binlun Yan, Huan Gao

“…To explore whether this phenomenon also existed in other tissues, we used the bisulfite method (BSP) to detect the methylation of the mitochondrial genome in the intestinal tissues, hepatopancreas, gills, eye stalks, muscles, heart, and other tissues before and after starvation. …”
Get full text

Prevalence and risk factors of schistosomiasis among primary school children in four selected regions of The Gambia. by Ebrima Joof, Abdoulie M Sanyang, Yaya Camara, Alhagie Papa Sey, Ignatius Baldeh, Sharmila Lareef Jah, Serign Jawo Ceesay, Sana M Sambou, Saikou Sanyang, Christopher M Wade, Bakary Sanneh

“…Prevalence of urinary schistosomiasis was significantly different among regions (χ 2 = 279.958, df = 3, p < 0.001), with CRR (27.6%) being the most endemic region, followed by URR (12.0%), then LRR (0.6%), and NBR (0.0%). Prevalence of intestinal schistosomiasis was also significantly variable among regions, with 4 of the 5 positive cases detected in CRR and 1 case in URR. …”
Get full text