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Isolation, establishment, and characterization of immortalized ileum bovine intestinal epithelial cell line
Published 2025-07-01“…Abstract Primary intestinal epithelial cells are a powerful tool to study tight junction protein function and barrier integrity of epithelial cells. …”
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Sintilimab-induced intestinal obstruction and hemorrhage of the digestive tract: a case report
Published 2025-07-01“…The patient developed intestinal obstruction, abdominal pain, hemorrhage of the lower digestive tract and other discomfort and was diagnosed with multiple jejunal ulcers via colonoscopy and pathological biopsy. …”
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Galla chinensis alleviated liver damage induced by acetaminophen by regulating intestinal microbiota
Published 2025-07-01“…Additionally, GC demonstrated the ability to regulate the diversity and composition of intestinal microbes and help increase the prevalence of beneficial microbes such as Faecalibaculum and Odoribacter while reducing the prevalence of pathogenic bacteria, including Corynebacterium, Rikenella, Bacillus, Phocaeicola, and Alloprevotella.DiscussionOur findings indicate that GC plays a significant role in mitigating drug-induced liver injury by improving gut microbiome composition, reducing plasma ALT and AST levels, and inhibiting oxidative stress and inflammatory responses. …”
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Assessing Intestinal Health in Pigs: Recognizing Unaddressed Areas and Prospective Research Avenues
Published 2025-05-01“…In the database, 87% of intestinal health assessments were combined with growth performance measures. …”
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Correlation of the intestinal flora and its metabolites with the colonic transport function in functional constipation
Published 2025-05-01“…BackgroundFunctional constipation (FC) is a clinically frequent intestinal disorder. A growing body of evidence emphasizes the link between intestinal microecological imbalance and constipation. …”
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Microbial-Derived Antioxidants in Intestinal Inflammation: A Systematic Review of Their Therapeutic Potential
Published 2025-03-01“…Among the main findings are certain compounds, such as exopolysaccharides (EPS) and short-chain fatty acids (SCFAs), which have demonstrated their ability to neutralize ROS and strengthen the integrity of the intestinal barrier, thereby attenuating inflammatory responses. …”
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Development and validation of a nomogram model to predict the risk of strangulated intestinal obstruction
Published 2024-12-01“…Abstract To develop and validate a nomogram model for discriminating simple intestinal obstruction and strangulated intestinal obstruction, thus providing objective evidence for clinical decision-making. …”
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Effect of Chronic Consumption of Sweeteners on Microbiota and Immunity in the Small Intestine of Young Mice
Published 2019-01-01“…The chronic consumption of sweeteners increases the population of lymphocytes in the mucosa of the small intestine. Maybe, Bacillus have the ability to adapt to sweeteners regardless of the origin or nutritional contribution of the same.…”
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Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice
Published 2025-04-01“…Conclusions Taken together, we demonstrate that life-long and repeated transfer of microbiota material from young mice improved age-related processes including coordinative ability (rotarod), intestinal permeability, and both metabolic and inflammatory profiles mainly of macrophages but also of other immune cells. …”
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Spontaneous brain activity in patients with type 2 diabetes: linking serum neuroproteins to cognitive ability
Published 2025-05-01“…Mediation analysis were performed to examine the potential causal chain between the neuroproteins and cognitive ability. Results The levels of Epiregulin (EREG), Abhydrolase domain containing 14B (ABHD14B) and Inositol monophosphatase 1 (IMPA1) decreased, while the level of Cysteine-rich intestinal protein 2 (CRIP2) increased in type 2 diabetic patients with MCI (FDR p < 0.05). …”
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The positive effects of dietary inositol on juvenile hybrid grouper (♀Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatu) fed high-lipid diets: Growth performance, intestinal dig...
Published 2024-12-01“…In summary, supplementing high-lipid diets with appropriate inositol can enhance digestive ability, improve the morphology of hybrid grouper intestines, increase the abundance of beneficial bacterial microbiota, maintain intestinal health, and promote growth.…”
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Intestinal Probiotic Lysate Modified Bifunctional Nanoparticle for Efficient Colon Cancer Immunotherapy
Published 2025-01-01“…<b>Conclusions:</b> Our study developed a novel intestinal probiotic lysate-based gene delivery system with dual immunomodulatory abilities, suggesting a potential strategy for cancer immunotherapy.…”
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Lactoferrin promotes intestinal stem cell‐mediated epithelial regeneration by activating Wnt signaling
Published 2024-09-01“…Lactoferrin (LF) is a natural milk‐abundant protein with several gut health‐related functions such as antibacterial and immunoregulation activities, thus protecting intestine from damage. However, it is unclear whether LF also plays a role in the repair of the injured intestine, despite limited clues on its ability to modulate intestinal epithelial cell growth in vitro. …”
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Evaluating the role of insulin resistance in chronic intestinal health issues: NHANES study findings
Published 2025-05-01“…BackgroundIntestinal health issues affect approximately 20% of the global population, yet the relationship between insulin resistance (IR) and intestinal health remains poorly understood. …”
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Behavioral Cooperation or Conflict of Human Intestinal Roundworms and Microbiomes: A Bio-Activity Perspective
Published 2025-04-01“…When nematodes infect a host, the microbiome composition changes, and this can impact the host’s ability to control the parasites. We aimed to find out if the small intestinal roundworms produce substances that have antimicrobial properties and respond to their microbial environment, and if the immune and regulatory reactions to nematodes are altered in humans lacking gut microbes. …”
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Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders
Published 2024-01-01“…The human intestinal epithelium has an impressive ability to respond to insults and its homeostasis is maintained by well-regulated mechanisms under various pathophysiological conditions. …”
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Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila
Published 2025-04-01“…IntroductionIntestinal stem cells (ISCs) possess the ability to self-renew and differentiate, which is essential for maintaining intestinal tissue homeostasis. …”
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RNA-seq analysis of small intestine transcriptional changes induced by starvation stress in piglets
Published 2024-12-01“…In this study, we analysed the ileum of Large White (LW) and Mashen (MS) piglets at different times of starvation using chemical staining and transcriptome analysis. The intestinal barrier of piglets was damaged after starvation stress, but the intestinal antistress ability of MS piglets was stronger than LW piglets. …”
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Comparative analysis of commercial and “In-House” molecular tests for the detection of intestinal protozoa in stool samples
Published 2025-08-01“…Microscopy remains the reference diagnostic method for intestinal protozoa, but is limited in terms of sensitivity, specificity and the ability to differentiate closely related species. …”
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