Structures and strategies for retaining an international pediatric cohort from birth: Lessons from The Environmental Determinants of Diabetes in the Young (TEDDY) study by Patricia Gesualdo, Jessica Melin, Rachel Karban, Claire Crouch, Michael Killian, Diane Hopkins, Annika Adamsson, Joanna Stock, Suzanne Bennett Johnson, Judith Baxter

“…Strategies unique to TEDDY included (1) study structures to support retention; (2) risk communication and education strategies specific to this population; (3) Data-informed retention strategies that addressed protocol challenges in real-time; and (4) implementation of a re-engagement protocol for those who had withdrawn from the study. …”
Get full text

Influence of symptom burden on social alienation in lung cancer patients receiving chemotherapy: the chain mediating effect of perceived social support and positive psychological c... by Jiahao Wei, Ziye Bai, Mengru Bu, Guining Dang, Xiumei Wu, Jin Zhou

“…Data collection was conducted using a proprietary Sociodemographic Information Questionnaire, MD Anderson Symptom Inventory (MDASI), Social Alienation Questionnaire, Perceptions of Social Support (PSS) Questionnaire, and Positive Psychological Capital (PPC) Questionnaire. …”
Get full text

FreshWater Watch: Investigating the Health of Freshwater Ecosystems, from the Bottom Up by Isabel Bishop, Amedeo Boldrini, Wim Clymans, Charlotte Hall, Heather Moorhouse, Stephen Parkinson, Kesella Scott-Somme, Ian Thornhill, Steven Loiselle

“…We explore the evolution of protocols used to ensure data robustness and transferability and examine the utility of contextual information registered by citizen scientists. We present laboratory and field experiments conducted to validate chemical and optical methods. …”
Get full text

The philosophical foundations of digital twinning by David J Wagg, Christopher Burr, Jason Shepherd, Zack Xuereb Conti, Mark Enzer, Steven Niederer

“…The concept is very versatile and has been adopted by multiple communities of practice, policymakers, researchers, and innovators. A significant part of the digital twin paradigm is about interconnecting digital objects, many of which have previously not been combined. …”
Get full text

Investigation of factors that affect post-fire recovery of photosynthetic activity at global scale by Yicheng Shen, I. Colin Prentice, Sandy P. Harrison

“…Factors affecting post-fire recovery time have been investigated at site or regional scale, but there is comparatively little information about this at a global scale. In this study, we use solar-induced chlorophyll fluorescence (SIF) to estimate the recovery of photosynthetic activity after fire for more than 10,000 fires representing the range of ecosystems across the globe. …”
Get full text

Integrated microfluidics-based construction of anti-BTN2A2 gel droplet cell preparations for non-invasive tumor-infiltrating lymphocyte therapy by Yishen Tian, Jingxuan Li, Na Yang, Yang Zhao, Jiancao Zuo, Hang Xiong, Yiwen Pan, Li Xiao, Min Su, Feng Han, Zhixu He, Rong Hu

“…., regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSC)) in solid tumors when infused back into the treatment will prevent T cell infiltration and proliferation, thus inhibiting the efficacy of this approach. …”
Get full text

Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis by Hua Feng, Xiulian Xu, Shuzhen Qi, Kun Chen, Mei Ju, Xiaofang Li, Shuxian Shang

“…Mediation analysis indicated that knowledge (β = 0.24, P = 0.023), attitude (β=-0.28, P < 0.001), disease duration (β=-1.49, P < 0.001), and negative emotions (β=-1.54, P = 0.008) had direct effects on practice. Income (β=-0.29, P = 0.003), disease duration (β = 0.16, P = 0.033), lesion duration (β = 0.25, P = 0.003), education (β = 0.11, P = 0.024), and age (β=-0.14, P = 0.036) had indirect effects on practice. …”
Get full text

Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X by Melanie P. Muller, Alex Mortenson, Josepha C. Sedzro, Po-Chao Wen, James H. Morrissey, Emad Tajkhorshid

“…Residue-residue contact information was then used in nonequilibrium simulations to drive the formation of the EC on a phosphatidylserine/phosphatidylcholine membrane surface, providing, to our knowledge, the first membrane-bound model for the EC. …”
Get full text

The Potential Applications of Stem Cell Conditioned Medium Secretome in Knee Cartilage Regeneration: A Systematic Review by I Gusti Ngurah Wien Aryana, Febyan Febyan, Nyoman Gede Grenata Nanda Ustriyana

“…Hydrogel-based systems techniques and 3D-printed scaffolds have emerged for innovative delivery. Specific microRNAs, such as miR-92a-3p, have been recognized for enhancing cartilage regeneration. …”
Get full text

Minute-cadence Observations of the LAMOST Fields with the TMTS. VI. Physical Parameters of Contact Binaries by Qiqi Xia, Xiaofeng Wang, Kai Li, Xiang Gao, Fangzhou Guo, Jie Lin, Cheng Liu, Jun Mo, Haowei Peng, Qichun Liu, Gaobo Xi, Shengyu Yan, Xiaojun Jiang, Jicheng Zhang, Cui-Ying Song, Jianrong Shi, Xiaoran Ma, Danfeng Xiang, Wenxiong Li

“…The absolute physical parameters were inferred with the W-D code for 10 systems, all of them are W-type shallow or medium contact binaries. …”
Get full text

Progress Analysis and Development Prospects of Soil Ecological and Environmental Effects of Interlayer Construction by JIA Zhenjiang, WU Yangyang, LI Wangcheng, MA Dongxiang, CHEN Jihong, GAO Susu, NIU Xiaoxiao, XU Tianyuan

“…Within the framework of the dual carbon development pattern and multiple strategic overlapping context, the focus and direction of future research will be on innovating and technologically transforming new interlayer materials based on the efficient utilization of solid waste resources.…”
Get full text

Impact of One Year Covid-19 on Hand and Upper Extremity Injury: A Cross-Sectional Study by Pamudji Utomo, Tito Sumarwoto, Naufal Aminur Rahman, Mochammadsyah Beizar Yudhistira

“…Despite this, there is scarce information about the many forms and causes of hand and upper extremity injuries. …”
Get full text

Hexane extract from Lindera communis roots: wound healing properties and membrane-disruptive activities against methicillin-resistant Staphylococcus aureus by Miaomiao Wang, Miaomiao Wang, Miaomiao Wang, Xian Hu, Xian Hu, Xian Hu, Liya Liu, Liya Liu, Liya Liu, Liya Liu, Yi Zhong, Yi Zhong, Yi Zhong, Wanlin Li, Wanlin Li, Wanlin Li, Qing Zhang, Qing Zhang, Qing Zhang, Congli Xu, Chunlin Long, Chunlin Long, Chunlin Long, Chunlin Long, Chunlin Long

“…LCH also has exhibited remarkable effectiveness in healing rat excisional wounds, reinforcing its traditional use as a wound-healing agent.DiscussionThe findings substantiate the scientific essence of traditional applications, while also exhibiting significant potential as a promising candidate for the development of innovative and readily accessible wound healing agents.…”
Get full text

ClimaWATCH: A new interactive tool for community heat-health vulnerability assessments by Aparna Keshaviah, Dheeya Rizmie, Huihua Lu, Mike Rudacille, Eric Morris, Colleen Psomas, Farid Qamar, Xindi C. Hu

“…To boost heat preparedness and response, officials need information on where heat-related health issues concentrate and how risks vary by demographic, social, environmental, and infrastructural factors. …”
Get full text

“Common sense is hard work” but benefits from persistent collaboration: Lessons learnt from the development of The Collaborative Network for European Clinical Trials for Children (... by Sabah Attar, Carla Peacock, Mandy Wan, Erin Halil, Chloe Bickerstaff, Lionel Tan, Hafsah Bhatti, Ricardo M. Fernandes, Regis Hankard, Mark A. Turner

“…Practical actions that infrastructure developers and users can take include operational planning with a view to fostering collaborations across stakeholders, sharing information about different approaches to clinical operations, and raising awareness of the need for explicit work on collaboration, communication, and planning. …”
Get full text

The Feasibility and Acceptability of a Community Science Approach to Explore Infant Formula Preparation Safety in the Home by Sara Jones, Jonie Cooper, Abbie Dolling, Tara McNamara, Susan Dvorak, Vicky Sibson, Amy Brown, Emma Yhnell, Phyll Buchanan, Sharon Breward, Rebecca Ellis, Aimee Grant

“…Parents often seek out information about health and parenting topics, but despite this, there have been few attempts to actively engage them in the research process. …”
Get full text

Tritordeum, barley landraces and ear photosynthesis are key players in cereal resilience under future extreme drought conditions by Ander Yoldi-Achalandabaso, Aitor Agirresarobe, Artūrs Katamadze, Giulia Burini, Omar Vergara-Díaz, Mariana Mota, Cristina Oliveira, Usue Pérez-López, Rubén Vicente

“…For that, we conducted an innovative approach combining a late-sowing field trial with two contrasting water regimes to simulate future extreme drought conditions, the use of high-throughput phenotyping devices and an infrared gas analyser to characterise leaf and ear photosynthesis, biochemistry, growth, and stress responses during the reproductive stage, and a novel linear mixed-effects model to integrate these results with final agronomical data. …”
Get full text

The natural course of cystic pancreatic neuroendocrine tumours in MEN1 by Eline N M van Vliembergen, Carolina R C Pieterman, Annenienke C van de Ven, Arthur J A T Braat, Gerlof D Valk, Joanne M de Laat

“…While solid PanNETs are generally considered to have an indolent course, the natural course of cystic lesions remains unclear. …”
Get full text

Charge-on-the-move solutions for future mobility: A review of current and future prospects by Mohd Aiman Khan, Wilco Burghout, Oded Cats, Erik Jenelius, Matej Cebecauer

“…Simultaneously, emerging transportation modes such as autonomous vehicles, shared mobility, modular systems, and aerial vehicles, introduce additional complexities, demanding more innovative charging solutions. This review emphasizes the potential of charge-on-the-move systems referred to as dynamic charging, as a transformative approach to address these challenges. …”
Get full text

A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes by Cara Jeffrey, Cara Jeffrey, Cara Jeffrey, Laura Ziems, Laura Ziems, Brent Kaiser, Brent Kaiser, Richard Trethowan, Richard Trethowan

“…GDD and SDD were shown to be useful for predicting genotype adaptation to locations and seasons thus providing a basis for varietal recommendations. This information could also be used to breed environment specific cultivars and to understand trait plasticity.…”
Get full text