A multicenter, randomized, open label, two formulation, crossover bioequivalence trial of doxorubicin hydrochloride liposomal injection in Chinese patients with metastatic breast c... by Jingshu Wang, Xiuping Lai, Herui Yao, Hui Yang, Xiaolong Cao, Xiaochen Wang, Ying Wang, Weiqi Nian, Xiaodong Zheng, Qingxiu Mai, Anding Liu, Xiaozhi Lv, Xiaoying Bi, Junyi Chen, Junyan Wu, Suiwen Ye

“…Results The results indicated that the maximum concentration (Cmax), AUC from time zero to the last measurable concentration (AUC0-t), and AUC extrapolated to infinity (AUC0-∞) of in vivo non-encapsulated doxorubicin after administration of both formulations fell within the 80.00%–125.00% range at a 90% confidence interval. …”
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Islamic Religious Education Learning Strategies for Inclusion Students at Muhammadiyah High School by Fadhilla Nangroe Anggraini, Triono Ali Mustofa, Abil Fida Muhammad Qois Al Hadi

“…This study concludes that flexible, innovative, and inclusive learning strategies can enhance the academic and social potential of students with special needs. …”
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Severe COVID-19 disease is associated with genetic factors affecting plasma ACE2 receptor and CRP concentrations by Verena Vogi, David Haschka, Lukas Forer, Simon Schwendinger, Verena Petzer, Stefan Coassin, Ivan Tancevski, Thomas Sonnweber, Judith Löffler-Ragg, Elisabeth Puchhammer-Stöckl, Marianne Graninger, Dominik Wolf, Florian Kronenberg, Johannes Zschocke, Emina Jukic, Günter Weiss

“…To examine a potential role of common genetic factors that may influence COVID-19 outcomes, we investigated whether individuals with a polygenic predisposition for a pro-inflammatory response (in the form of Polygenic Scores) are more likely to develop severe COVID-19. The innovative approach of polygenic scores to investigate genetic factors in COVID-19 severity should provide a comprehensive approach beyond single-gene studies. …”
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Digital Safety for Women and Children: Legal and Policy Challenges Indonesia, Philippines, and Thailand by Dwi Nur Fauziah Ahmad, Nucharee Nuchkoom Smith

“…Key regulations such as the Electronic Information and Transactions (ITE) Law in Indonesia, the Cybercrime Prevention Act in the Philippines, and the Computer Crime Act in Thailand were analyzed alongside institutional reports and academic studies. …”
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Feature selection in single-cell RNA sequencing data: a comprehensive evaluation by Petros Paplomatas, Konstantinos Lazaros, Georgios N. Dimitrakopoulos, Aristidis Vrahatis

“…Our findings underscore the enduring necessity for further refinement and continuous innovation in the field of scRNA-seq analysis, aiming to enhance the accuracy of cell-type identification and improve overall data interpretation.…”
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Gaps in U.S. livestock data are a barrier to effective environmental and disease management by Rebecca Logsdon Muenich, Sanskriti Aryal, Amanda J Ashworth, Michelle L Bell, Melanie R Boudreau, Stephanie A Cunningham, K Colton Flynn, Kerry A Hamilton, Ting Liu, Michael L Mashtare, Natalie G Nelson, Barira Rashid, Arghajeet Saha, Danica Schaffer-Smith, Callie Showalter, Aureliane Tchamdja, Jada Thompson

“…In the U.S. the National Agricultural Statistics Service completes a Census once every 5 years that includes livestock, but data are only available at the county level leaving little inference that can be made at such a coarse spatiotemporal scale. …”
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Systematic analysis of the pharmacogenomics landscape towards clinical implementation of precision therapeutics in Greece by George P. Patrinos, Kariofyllis Karamperis, Margarita-Ioanna Koufaki, Maria Skokou, Zoe Kordou, Eirini Sparaki, Margarita Skaraki, Christina Mitropoulou

“…In several European populations, particularly in countries with lower income, clinical implementation of PGx is still in its infancy. …”
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RenalSegNet: automated segmentation of renal tumor, veins, and arteries in contrast-enhanced CT scans by Rashid Khan, Chao Chen, Asim Zaman, Jiayi Wu, Haixing Mai, Liyilei Su, Yan Kang, Bingding Huang

“…RenalSegNet has an innovative encoder-decoder architecture, including the FlexEncoder Block for efficient multivariate feature extraction and the MedSegPath mechanism for advanced feature distribution and fusion. …”
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Can Table Tennis Extend Lifespan? An Analysis of Its Impact on Physical Health, Brain Function, and Mental Well-being by Patrycja Marta, Agata Ossolińska, Filip Huzarski, Gabriela Ferfecka, Klaudia Pawełek, Lucyna Stolarska, Magdalena Rosa-Bończak, Natalia Morawiecka, Olivier Carlton, Weronika Kłosowicz

“…Materials and Methods: This analysis is based on a detailed review of studies and information related to table tennis, sourced from PubMed and Google Scholar databases. …”
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Phubbing as a Social Norm: Effects on Fear of Missing Out (FoMO) and Perceived Exclusion by Miguel Ángel Albalá-Genol, Edgardo Etchezahar, Talía Gómez-Yepes, Joaquin Ungaretti

“…Technology and social media have transformed the way we communicate, interact, and stay informed. Phubbing is a term that comes from two words «phone» and «snubbing» and represents the act of ignoring a person in a real life setting by paying attention to their cell phone. …”
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National survey of US primary care physicians’ perspectives about causes of obesity and solutions to improve care by Wendy L Bennett, Sara N Bleich, Kimberly A Gudzune, Lisa A Cooper

“…Physicians with fewer than 20 years since completion of medical school were more likely to identify lack of information about good eating habits and lack of access to healthy food as important causes of obesity. …”
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A Woman with Double Intra Uterine Device: A Case Report by Işık Gönenç, Zeynep Tuzcular Vural, Nurettin Aka, Can Ertuğrul Tüfekçi, Gültekin Köse

“…The patient’s medical history revealed that a copper-T intra uterine device (IUD) had been inserted ten years ago, and that she had a normal vaginal delivery seven years after, when she was informed by her physician that her IUD had been expelled and she conceived afterwards. …”
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Health Concerns as the Fundamental Dietary Choices for Potential Stunting Preventions: a Qualitative Study by Inne Soesanti, Taufiqurrahman Taufiqurrahman, Ani Intiyati, Sri Hidayati

“…Methods: This study used a qualitative approach with an ethnographic design. The informants were eleven mothers and grandmothers whose children were under two years old. …”
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Decisions about the use of psychotropic medication during pregnancy: a qualitative study by Irene Petersen, Vanessa Pinfold, Sarah Hamilton, Fiona Stevenson, Charlotte Walker, Ceri R J Dare, Harminder Kaur, Ruth Lambley, Paulina Szymczynska, Vicky Nicolls

“…In nearly all cases, the women expressed the view that healthcare professionals had access to limited information leaving women to rely on experiential and common sense evidence when making decisions about medicine taking during pregnancy.Conclusions The findings complement existing work using electronic health records by providing explanations for the discontinuation of psychotropic medicines in pregnancy. …”
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Antioxidants and Cognitive-Behavioral Therapy in Patients with Functional Dyspepsia by T. V. Sapozhnikova, S. A. Parfenov, T. E. Yesina, K. V. Sapozhnikov, A. N. Smirnov, A. A. Paulov, D. M. Rizakhanov, O. A. Rizakhanova

“…Based on the collection of a small amount of anamnestic information (the duration of functional dyspepsia, the presence of an acute stress factor in the anamnesis), the assessment of the presence of an overlap syndrome and disadaptation in relation to the patient to his illness, the value of the discriminant function is calculated. …”
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Double Stokes polarimetric microscopy for chiral fibrillar aggregates by Viktoras Mazeika, Kamdin Mirsanaye, Leonardo Uribe Castaño, Serguei Krouglov, Mehdi Alizadeh, Mykolas Maciulis, Lukas Kontenis, Vitalijus Karabanovas, Virginijus Barzda

“…Polarimetric SHG measurements provide ultrastructural information about the fibrillar organization in a focal volume (voxel). …”
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Seasonal recurrence and modular assembly of an Arctic pelagic marine microbiome by Taylor Priest, Ellen Oldenburg, Ovidiu Popa, Bledina Dede, Katja Metfies, Wilken-Jon von Appen, Sinhué Torres-Valdés, Christina Bienhold, Bernhard M. Fuchs, Rudolf Amann, Antje Boetius, Matthias Wietz

“…By integrating taxonomic, functional and environmental information, our study provides fundamental insights into how microbiomes are structured under pronounced seasonal changes in understudied, yet rapidly changing polar marine ecosystems.…”
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Value Engineering Study on Canal Rehabilitation Work Using Cultures in Samarinda Ulu District by Ibnu Khaldun, Wateno Oetomo

“…This research method was carried out in five stages of Value Engineering, namely the information stage, function analysis stage, creative stage, evaluation stage and presentation stage. …”
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Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings by J Cloete, M Karsas, T Chetty, A Pillay, M Archary, D Moore, T Reddy, Y Balakrishna, F Nakwa, R Lancaster, A Goga, P Jeena

“…Paediatric inpatients are particularly vulnerable to infections, leading to high antimicrobial consumption. In low-to-middle income countries (LMICs) like South Africa, research on antimicrobial usage for neonatal and paediatric healthcare-associated infections (HAI) is limited. …”
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Left Atrial Appendage Occlusion: Expanding Indications and New Developments by Grant W. Reed, MD, MSc, Shady Nakhla, MD, Rhonda Miyasaka, MD, Serge Harb, MD, Mohamed Kanj, MD, Ousamma Wazni, MD, Samir R. Kapadia, MD, Amar Krishnaswamy, MD

“…Percutaneous left atrial appendage occlusion (LAAO) is recommended in several major international society guidelines as a viable alternative to therapeutic anticoagulation for the prevention of ischemic stroke in patients with nonvalvular atrial fibrillation or flutter. Recent innovations in device development have improved the safety and procedural success of LAAO, further fueling enthusiasm for expanding its indications beyond patients with high-bleeding risk from oral anticoagulation use. …”
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