NOTCH and Tumor Necrosis Factor-Alpha Converting Enzyme Levels Could be used in COVID-19 for Risk Stratification by Dilay Karabulut, Gülçin Şahingöz Erdal, Cennet Yildiz, Gülsüm O Hergünsel, Umut Karabulut, Elif Binboğa, Nilgun Isiksacan

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Associations of glycated hemoglobin with hemoglobin levels and erythrocyte parameters by Ye.I. Dzis, O.Ya. Tomashevska, I.Ye. Dzis, N.Ya. Tomashevska

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Fagopyrum dibotrys protects gut health in broiler chickens fed oxidized oil by Lulin Tan, Xue Han, Liang Li, Lina Li, Yulong Feng, Qingfeng Wang

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Manganese mitigates atrazine-induced oxidative stress and hepatorenal toxicity: insights from network pharmacology and in vivo experimentation by Solomon E. Owumi, Tella T. Adedayo, Joseph Chimezie, Bayode Oluwawibe, Harieme Agbarogie, Jesutosin O. Babalola, Oludare M. Ogunyemi, Uche O. Arunsi, Moses T. Otunla, Chioma E. Irozuru, Ahmad Altayyar, Eziuche A. Ugbogu

“…The findings suggest that Mn mitigates oxidative stress, inflammation, and hepatorenal damage through multiple molecular and biochemical mechanisms.…”
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miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages by Carmen Alexandra Neculachi, Evelyn-Gabriela Nastase-Rusu, Laudy Cherry, Catalina Iolanda Marinescu-Colan, Spyros Tastsoglou, Bogdan Paul Cosman, Alina Madalina Popa, Cristina Panciuc, Germana Zaccagnini, Germana Zaccagnini, Sergiu Bogdan Catrina, Sergiu Bogdan Catrina, Maya Simionescu, Fabio Martelli, Fabio Martelli, Mihai Bogdan Preda, Alexandrina Burlacu

“…The fine-tuned involvement of miR-210 in immune responses may have potential implications for chronic inflammation, immune dysfunction, and tissue repair.…”
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Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin by Qianyu Bai, Zhongling Zhao, Yujing Duan, Runqiu Cai, Yinzhu Chen, Chaoyu Zhou, Xinyuan Tian, Yifei Yang, Haiyan Wu, Mingju Li, Jia You, Qingyi Song, Hong Dong, Tianlong Liu

“…IntroductionConventional approaches to treat ulcerative colitis (UC) focus on suppressing excessive inflammation and immune responses. Nevertheless, these treatments fail to address gut dysbiosis or restore the intestinal mucosal barrier effectively. …”
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A novel C-3-substituted oleanolic acid benzyl amide derivative exhibits therapeutic potential against influenza A by targeting PA–PB1 interactions and modulating host macrophage in... by Kunyu Lu, Jianfu He, Chongjun Hong, Haowei Li, Jiaai Ruan, Jinshen Wang, Haoxing Yuan, Binhao Rong, Chan Yang, Gaopeng Song, Shuwen Liu

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The CCL5/CCR5/SHP2 axis sustains Stat1 phosphorylation and activates NF-κB signaling promoting M1 macrophage polarization and exacerbating chronic prostatic inflammation by Chen Jin, Fei Zhang, Hailang Luo, Boyang Li, Xue Jiang, Christopher J. Pirozzi, Chaozhao Liang, Meng Zhang

“…Abstract Background and objective Chronic prostatitis (CP) is a condition markered by persistent prostate inflammation, yet the specific cytokines driving its progression remain largely undefined. …”
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The unexpected role of the STING protein in lipid metabolism by Vila, Isabelle K., Laguette, Nadine

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DNA methylation in necrotizing enterocolitis by Lauren C. Frazer, Yukihiro Yamaguchi, Dhirendra K. Singh, Natalia S. Akopyants, Misty Good

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The APOE–Microglia Axis in Alzheimer’s Disease: Functional Divergence and Therapeutic Perspectives—A Narrative Review by Aiwei Liu, Tingxu Wang, Liu Yang, Yu Zhou

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Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin by Guilherme Dias de Melo, Françoise Lazarini, Florence Larrous, Lena Feige, Etienne Kornobis, Sylvain Levallois, Agnès Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre‐Marie Lledo, Jean‐Pierre Changeux, Hervé Bourhy

“…Whereas it has no effect on viral load in the airways of infected animals, transcriptomic analyses of infected lungs reveal that IVM dampens type I interferon responses and modulates several other inflammatory pathways. …”
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Immunomodulatory role of spleen tyrosine kinase in chronic inflammatory and autoimmune diseases by Yaqi Zhou, Yaowen Zhang, Wei Yu, Yufen Qin, Heng He, Fengxian Dai, Yibo Wang, Fengqin Zhu, Guangxi Zhou

“…Splenic tyrosine kinase (SYK) is a non–receptor tyrosine kinase that plays an important role in immune receptor signalling in immune and inflammatory responses. Methods This is a review article in which we searched for keywords “splenic tyrosine kinase”, “inflammation” and “autoimmune diseases” in published literature such as Pubmed and Web of Science to collect relevant information and then conducted a study focusing on the latest findings on the involvement of SYK in chronic inflammatory or autoimmune diseases. …”
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Astaxanthin-rich Nannochloropsis oculata mitigates high-fat diet-induced liver dysfunction in zebrafish by modulating lipid metabolism and oxidative stress by Shima Jafari, Mohammad Akhavan-Bahabadi, Seyed Pezhman Hosseini Shekarabi, Mehdi Shamsaie Mehrgan, Elly Lowen, Kasra Lotfi, Azin Azari

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IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy by V. B. Berdichevsky, B. A. Berdichevsky, A. V. Romanova, F. R. Rasulov, A. A. Naletov, S. V. Khilkevich, E. I. Gutrova, A. L. Boldyrev, M. A. Korabelnikov

“…Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. …”
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Vaginal Microecology Disturbance and Immune Dysregulation Are Associated with Human Papillomavirus Infection: Insights from a Two-year Study of Vaginal Microecology by Sheng Q, Cui X, Zhang J, Yang F, Zeng L

“…Vaginal microecology and immune responses may play pivotal roles in determining HPV outcomes. …”
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Plasma concentrations of extracellular vesicles correlate with inflammatory markers in patients with aortic stenosis undergoing surgical aortic valve replacement by Tomasz Urbanowicz, Anna Olasińska-Wiśniewska, Ewelina Błażejowska, Aleksandra Gąsecka, Michał Michalak, Krzysztof J. Filipiak, Michał Rodzki, Anna Witkowska, Michał Bociański, Andrzej Tykarski, Marek Jemielity

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Macrophages in bacterial lung diseases: phenotype and functions (review) by E. G. Churina, A. V. Sitnikova, O. I. Urazova, S. P. Chumakova, M. V. Vins, A. E. Beresneva, V. V. Novitskii

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Parameters of the systemic inflammatory response and their relationship with atrial fibrillation in patients with ST-elevation myocardial infarction after percutaneous coronary int... by B. I. Geltser, K. I. Shahgeldyan, R. L. Pak, I. G. Domzhalov, E. An. Kokarev, V. N. Kotelnikov

“…Previously developed (neutrophil/lymphocyte (NLR), platelet/lymphocyte (PLR), monocyte/lymphocyte (MLR), systemic immune inflammation index (SII), systemic inflammatory response index (SIRI) and systemic inflammation total index (AISI)) and novel inflammatory response indicators (neutrophil/eosinophil ratio (NER) and neutrophil/basophil ratio (NBR)) were calculated.Results. …”
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Significant Reduction of Chenodeoxycholic Acid and Glycochenodeoxycholic Acid in the Elderly with Severe COVID-19 by Shiyang Liu, Wen Xu, Bo Tu, Zhiqing Xiao, Xue Li, Lei Huang, Xin Yuan, Shengdong Luo, Juanjuan Zhou, Xinxin Yang, Junlian Yang, De Chang, Weiwei Chen, Fu-Sheng Wang

“…CDCA and GCDCA levels at admission predicted disease progression, suggesting their potential as biomarkers for severe COVID-19 in the elderly and highlighting their regulatory role in inflammation, pointing to new therapeutic avenues.…”
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