Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies by Jifeng Gu, Jifeng Gu, Huishan Zhang, Mei Wang, Yuyang Zhou, Yuyang Zhou, Zhipeng Deng, Rong Shi

“…Furthermore, molecular simulations showed that tectorigenin and irigenin bind to the orthosteric site of CYP isoforms via hydrogen bonds and π-π stacking, whereas irisflorentin is principally bound to CYP1A2 via π-π stacking and hydrophobic interactions.ConclusionCollectively, these Iridaceae isoflavone aglycones can be metabolized by CYP enzymes with typical or atypical kinetic characteristics. …”
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Health and Educational Inequalities among the Third Gender Community in Lahore, Pakistan by Ayesha Humayun, Muhammad Hassan, Hira Ashfaq, Zulqarnain Haider, Nauman Naeem, Mubashar Munir

“…Conclusion: The third gender community faces significant barriers in accessing education and healthcare, depriving them of basic human rights. Urgent policy reforms promoting equity, inclusivity, and community sensitization are needed to end their social neglect. …”
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Functional Outcome of Mesenchymal Stem Cells Vs. Hyaluronic Acid in Knee Osteoarthritis Kellgren-Lawrence Grade I-III At 6-and 12-Months Follow-Up: A Meta-Analysis by I Gusti Ngurah Wien Aryana, Febyan, Shianita Limena

“…Background: Osteoarthritis (OA) is a degenerative synovial joint disease with progressive pain and deformity. Stem cell therapy, especially mesenchymal stem cells (MSCs), has revolutionized the treatment of knee OA. …”
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Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau by WANG Zhenliang, CHEN Manyu, ZHAO Jianlin, YUAN Ke, YANG Jie, ZHANG Chen

“…[Results] (1) A total of 107 landslides from 2017 to 2021 were identified, including the specific location and accelerated deformation time of landslides. (2) With the increase of rainfall days in the early period, the correlations between cumulative rainfall and landslide shape variables showed a trend of first increasing and then decreasing. …”
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Study on seismic performance of high-strength steel earthquake-resilient beam-column joint with double damage elements by Hongchao Guo, Dongdong Zheng, Jing Lu, Xudong Zhou, Wenqi Wang, Yunhe Liu

“…In contrast, main components like beams and columns dissipate less than 10% of energy. The residual deformation of the joints is within the specified DS2 level limit in the FEAM P-58 standard, indicating excellent post-earthquake recoverable performance. …”

Measurement the Physiological Properties of Water Pipe Smokers in Shekhan Distract by Abdullah. M. Al-Saiegh, Turki Sabri Haji, Jihan Saado Ahmed, Alaa Azzo Aslo, Firas Faris Khalaf

“…Smoking is one of the old habits used by humans before 400 years ago, where this custom was exclusively used in males with the development of time, tools, ingredients and flavors that used in hookah the women also started smoking, which led to an increase in the prevalence of use in many countries of the world Smoking is one of the reasons that lead to an increase in the percentage incidence of lung cancer, chronic lung disease ,mouth disease ,teeth deformation and gingivitis. The aim of study to determine physiological status before, during and after smoking water pipe. …”
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An assessment of South African policy and strategic framework for the development of a sufficient, equitably distributed and well-performing health workforce for the implementation... by S V Mokoena, P Naidoo

“…The study was undertaken in SA with decision- makers and/or those who contribute to health sector reforms in SA in the realisation of the National Health Insurance (NHI). …”
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An advanced technique to adjust hull girder load: Part 1 = generalisation by Chang Hwan Jang, Do Kyun Kim

“…If the forces are placed by considering only the position of the nodes, the loads may be concentrated or applied in a different direction from the placement of the elements, resulting in unexpected stresses or deformations in the structural analysis. It is necessary to consider not only the node position but also the size and orientation of the element for force distribution. …”
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Microstructural analysis and preliminary wear assessment of wire arc additive manufactured AA 5083 aluminum alloy for lightweight structures by Prasanna Nagasai Bellamkonda, Maheshwar Dwivedy, Kaushik N.Ch

“…Under these conditions, deep grooves, layer separation, and load-induced deformation are observed. The primary wear mechanisms include delamination, adhesion, and abrasion. …”
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Assessment of the healing properties of Cichorium intybus L. extracts on wounds by Berivan Kaçmaz, Duygu Misirli, Seçil Erden Tayhan, Zafer Ömer Özdemir, Mahfuz Elmastaş

“…., or chicory, has been used for centuries to treat numerous illnesses and deformities. Purpose: The primary objective and novelty of this research endeavor involve the investigation of potential therapeutic attributes inherent in extracts derived from different components of C. intybus (common chicory), encompassing the root, stem, flower, and whole herba. …”
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BOOK REVIEW: CIPRIAN PORUMBESCU NECUNOSCUT (CIPRIAN PORUMBESCU UNKNOWN), PUBLISHING BY ED. LIDANA, SUCEAVA, 3 EDIŢII, 2011-2013 (ISSN: 2284-712X) by Gabriela COCA

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The Effect of Price Changes on Maize Farmers in Uganda: A Case Study of Kigando Sub-County Kyankwanzi District. by Twizukye, Juliet

“…These include but are not limited to the removal of bottlenecks in maize pricing by promoting effective maize market reforms. Once the Ugandan market channels and prices are freed, private traders can then bid up formally depressed maize prices. …”
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Suitability of Sand as Improvement to Mechanical Properties of Laterite Soil for Road Subbase. by Tumusiime, Darious

“…California Bearing Ratio (CBR) is a laboratory test used to determine the strength and resistance of a soil material to deformation under load. It is widely used in road construction to assess the suitability of soils for use as base materials and subbases. …”
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IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…• What is the potential of new forms of housing, such as shared housing, multi-generational housing, homeshare (housing for help)? …”
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IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…What is the potential of new forms of housing, such as shared housing, multi-generational housing, homeshare (housing for help)? …”
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Assessing the quality of life among African medical and health science students using the WHOQOL-BREF tool by Fatima Alzahra Galgam, Adil Abdalla, Mahmoud Shahin, Magda Yousif, Nahla Abdulrahman, Fatmah Alamoudi, Mehrunnisha Ahmad, Amira Yahia, Mohammad Sidiq, Aksh Chahal, Fuzail Ahmad, Mohammad Abu Shaphe, Gopal Nambi, Moattar Raza Rizvi, Faizan Kashoo

“…Background The quality of life (QoL) among health professional students is available in the literature, yet there is a paucity of information concerning QoL among African students. The study aimed to measure the QoL with the World Health Organization Quality of Life-BREF (WHOQOL-BREF) tool among African medical and health science students. …”
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The relationship between social support and depression among older adults with hypertension in urban communities: mediating effects of coping styles by Dan Li, Jin-Hua Jie, Hong Li, Xue-Mei Xia, Yilin Zhang, Yilin Zhang, Yan Yang, Yan Yang, Jianjun Xiang, Jianjun Xiang, Jianjun Xiang, Hai-Lin Zhuang

“…Participants were assessed for depression, social support, coping styles, and general demographic information. Pearson correlation analysis was employed to test the correlation between variables. …”
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A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Indonesian participants encounter additional challenges due to a fragmented information system and drug shortages. This study identifies key facilitators in providing high-quality care for LR-affected individuals, including financial assistance, availability of corticosteroid alternatives, timely provision of care, and counselling. …”
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Comprehensive analysis of endoscopic ultrasound (EUS) in mediastinal lesions: patient characteristics, diagnostic outcomes, safety, and efficacy: a multi-country study by Hussein Okasha, Eyad Gadour, Ghias Un Nabi Tayyab, Andrada Seicean, Elbacha Hicham, Emad Emad, Turki Alamri, Nadeem Tehami, Heero Ismael Faraj, Ahmed Alzamzamy, Hiwa Hussein, Mohammed Tag-Adeen, Mohamed Elbasiony, Abed Al-Lehibi, Shereen Saleh, Zaher Houmani, Mohamed Abdelghani, Khaled Ragab, Zahi Ismaili, Othmane Drir, Elsayed Ghoneem, Omar Abdallah, Souad Rebiai, Nonthalee Pausawasdi, Fedoua Rouibaa, Mohamed Borahma, Hassan Atalla, Mahmoud Farouk, Ahmed Altonbary

“…Methods This multi-country study involved a list of centers providing EUS services across ten countries—the United Kingdom, Algeria, Egypt, Iraq, Kingdom of Saudi Arabia (KSA), Lebanon, Morocco, Pakistan, Romania, and Thailand. The appropriate information was collected regarding EUS-FNA and EUS-FNB procedures, including needle types, nature of lesion, needle passes, and complications of the techniques. …”
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Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm by Dong Jiang, Yi Qian, Yijun Gu, Ru Wang, Hua Yu, Zhenmeng Wang, Hui Dong, Dongyu Chen, Yan Chen, Haozheng Jiang, Yiran Li

“…CEUS has a high accuracy rate in diagnosing the benign or malignant nature of gallbladder space-occupying lesions, which can significantly reduce the preoperative waiting time for related examinations and provide more reliable diagnostic information for clinical practice. Results Feature selection via Lasso led to a final LR model incorporating high-density lipoprotein, smoking status, basal width, and Rad_Signature. …”
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