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Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis
Published 2025-01-01“…Han Zheng,1,* Shan Xu,1,* Rui Yang,1,* Wo-Er Jiao,1 Yue-Long Qiao,1,2 Jia-Yu Liu,1 Hui-Ming Fan,1 Yan-Ting Zhou,1 Hai-Feng Ni,3 Jin Chen,1 Yu-Qin Deng,1 Shi-Ming Chen1 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; 3Department of Otolaryngology-Head and Neck Surgery, Zhejiang Hospital, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu-Qin Deng; Shi-Ming Chen, Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, Email bamboo0723@126.com; shimingchen0468@163.comBackground: The role of memory B cells and their subgroups in allergic rhinitis (AR) and allergen immunotherapy (AIT) remains unclear. …”
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When Technology Meets Anxiety:The Moderating Role of AI Usage in the Relationship Between Social Anxiety, Learning Adaptability, and Behavioral Problems Among Chinese Primary Schoo...
Published 2025-01-01“…GuangYuan Ma,1,* ShiQin Tian,1,* Yang Song,1 Yi Chen,1 Hui Shi,1 JingChi Li2 1School of Humanities and Management Science, Southwest Medical University, Luzhou, 646000, People’s Republic of China; 2Department of Orthopedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yang Song; Yi Chen, Email fookyuen666@163.com; chenyiswmu@163.comObjective: This study aims to examine the relationships between social anxiety, learning adaptability, AI technology usage, and behavioral problems among primary school students, with a focus on the mediating role of learning adaptability and the moderating role of AI usage.Methods: A cross-sectional survey was conducted among 1240 primary school students aged 8– 15 in Luzhou, Sichuan Province. …”
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6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy
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Construction and Validation of a Model for Predicting Fear of Childbirth: A Cross-Sectional Population Study via Machine Learning
Published 2025-02-01“…Zhi-Lin Zhang,* Kang-Jia Chen,* Hui Chen,* Miao-Miao Zhu, Jing-Jing Gu, Li-Shuai Jiang, Lan Zheng, Shu-Guang Zhou Department of Gynecology and Obstetrics, Maternal and Child Medical Center of Anhui Medical University, The Fifth Affiliated Clinical College of Anhui Medical University, Anhui Women and Children’s Medical Center, Hefei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shu-Guang Zhou, Email zhoushuguang@ahmu.edu.cn; Lan Zheng, Email zhenglan2022@163.comBackground: Fear of childbirth (FOC) is a psychological state of fear and distress that pregnant women experience when they approach labor. …”
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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension
Published 2025-01-01“…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study
Published 2025-02-01“…Hui-Wei Zhao,1 Shu-Tai Liu,2 Xiang-Jin Wang,1 Xue-Mei Zhang,1 Xiang Ma1 1Department of Periodontology, The Affiliated Yantai Stomatological Hospital, Binzhou Medical University, Yantai, 264000, People’s Republic of China; 2Department of Periodontology, Shenzhen Stomatology Hospital, Shenzhen, 518000, People’s Republic of ChinaCorrespondence: Xiang Ma, Department of Periodontology, The Affiliated Yantai Stomatological Hospital, Binzhou Medical University, 148 North Road, YanTai, People’s Republic of China, Email MaXiang900218@163.comBackground and Objective: Periodontitis is a chronic inflammatory disease caused by dental plaque accumulation, leading to damage of periodontal tissues and potential tooth loss. …”
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A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis
Published 2025-01-01“…Hui-Juan Li, Yue-Ying Zhou, He-He Yu, Jian Jiang, Yu-Wei Cai Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People’s Republic of ChinaCorrespondence: Yue-Ying Zhou, Department of Infectious Diseases, Wenzhou Central Hospital, No. 252 Baili East Road, Lucheng District, Wenzhou City, 325000, People’s Republic of China, Tel +86-0577-88882121, Email zhouyueying25@163.comObjective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. …”
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Predicting vasovagal reactions to needles from video data using 2D-CNN with GRU and LSTM.
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