Intrahepatic Cholestasis in Non-Alcoholic Fatty Liver Disease: Pathogenesis and Role of Ademetionine in Treatment by Ye. N. Shirokova

“…Concomitant IHC is present in 30 % of NAFLD patients, while it is associated with more active disease course and possible worsening of prognosis. Impairment of adipocyte and hepatocyte metabolism, gut dysbiosis, and inherent factors are recognized as significant factors for NAFLD development. …”
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INSTITUTIONAL QUALITY AND FINANCIAL CRIMES IN WEST AFRICA by Muhammed Lawal SUBAIR, Ahmed Ambal ISIAKA, Majeed Ajibola IBRAHIM, O.A. OYENIYI

“… The high level of financial crimes in West African countries have negatively impacted upon the smooth functioning of institutions, thus leading to the disintegration of social structures, negative economic expansion, decline in both domestic and international investment, and a worsening of the state of law and order throughout the region. …”
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Dental Age Estimation in A Sample of Kurdish Subjects (Aged 9-15 Years Old) in Erbil City Adopting Demirjian Method A Radiographic Study by Bayan Abdulla Hassan, Mahmoud Kanan Mohsin

“…Age estimation plays a great role in clinical dentistry, especially in orthodontics, pedodontics and forensic dentistry and aid in diagnosis and treatment planning. …”
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Clinical characteristics of hereditary spherocytosis with red blood cell membrane protein gene variants by Jingying Cheng, Liqiang Zhang, Jiafeng Yao, Shasha Zhao, Jin Jiang

“…Variation types included nonsense (21%), missense (27%), frameshift mutations (39%), splicing (8%), and large fragment deletions (4%). …”
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RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease by Zhaochen Guo, Shaohui Gao, Feng Xu, Zige Chen, Qinger Wang, Zhaojie Liu, Ziyue Wang, Weisong Qin, Caihong Zeng, Zhihong Liu, Hao Bao

“…The clinical management of diabetic nephropathy with tacrolimus remains challenging because of the risk of worsening hyperglycemia and infection. Results We developed two RGD-HSA-TAC nanoparticles designed for targeted delivery of tacrolimus to podocytes. …”
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Functional and Radiological Outcome of Surgical Management in Lumbar Spinal Stenosis – A Comparative Study by Makesh Ram Sriraghavan, Kandasamy Natesan, Pavalan Louis, Harish Shanmugam Punniakotti, Naveen Venkidusamy, Namala Sai Vinay Bharadwaj

“…Surgical intervention should be considered when conservative methods fail or if there is a progressive worsening of signs or symptoms. Most of surgical techniques are based on the principles of decompression with or without stabilization and fusion. …”
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Be Your Sister’s Keeper: Personal Experience of Travelling a Lonely Journey in Academia by Duduzile Mzindle

“…Whilst access is created by the system, there is very little support to enable black women to survive and succeed as they climb the bureaucratic ladder in neoliberal universities. The journey is worsened when one climbs the ladder and leaves sisters behind who choose to be ‘campers’ in these universities. …”
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Development of Applied Linguistics by Meilutė Ramonienė

“…Research in the field of language acquisition, sociolinguistics, language attrition, cognitive linguistics, pragmatics, politeness and impoliteness, corpus and forensic linguistics, and other branches of applied linguistics is presented, and the real-life linguistic issues, analysed by Lithuanian researchers, are highlighted. …”
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Airway clearance technique therapy for atelectasis induced by scoliosis surgery: a case report by Rui Zhai, Hairong Su, Yaxu Wu, Rong Tan, Xiaoli Zhang, Ye Tian, Mei Hu

“…Despite receiving medication for expectoration, postoperative symptoms including chest tightness, breathlessness, and ineffective coughing persisted and progressively worsened. Subsequent chest CT scans demonstrated extensive atelectasis, and pharmacological interventions proved to be ineffective. …”
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Analysis of toxicity and mechanisms of busulfan in non-obstructive azoospermia: A genomic and toxicological approach integrating molecular docking, single-cell sequencing, and expe... by Yanggang Hong, Qichao Yuan, Yi Wang, Deqi Wang, Xiaoju Guan, Congde Chen

“…Additionally, the immune landscape of NOA-affected testes revealed significant changes in immune cell infiltration, potentially worsening the condition. These findings offer new insights into the mechanisms of busulfan-induced NOA and suggest potential therapeutic targets for preserving male fertility in chemotherapy patients. …”
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Digital Safety for Women and Children: Legal and Policy Challenges Indonesia, Philippines, and Thailand by Dwi Nur Fauziah Ahmad, Nucharee Nuchkoom Smith

“…The results reveal that while these countries have made significant progress through the establishment of legal frameworks, implementation remains hindered by limited technical capacity, a lack of digital forensic expertise, and low public digital literacy. …”
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A unique case of extranodal marginal zone lymphoma with synchronous pulmonary and dermatologic manifestations by Carlo Arevalo, Fernando Camacho, Joseph Modrak

“…Despite aggressive diuresis, his respiratory distress worsened requiring up-titration of supplemental oxygen (6–8L/min). …”
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Long-term results of rectocele surgical treatment by Yu. A. Shelygin, A. Yu. Titov, O. M. Biryukov, A. A. Mudrov, L. P. Orlova, A. A. Tikhonov, Yu. A. Dzhanayev, M. A. Voynov

“…Analysis of results indicated, that evacuatory function of the rectum in the first 2 years after operation improved at 85,4% of patients, however eventually in 46,3% it worsened. It was found also, that results of operation did not depend on the method of rectocele surgery. …”
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Phantom-based investigation of block sequential regularised expectation maximisation (BSREM) reconstruction for zirconium-89 PET-CT for varied count levels by Lara M. Bonney, Matthew D. Walker, Daniel R. McGowan

“…For larger volumes, BSREM reconstruction enhanced image quality (lower noise) and maintained quantitation, whereas for smaller volumes quantitation worsened as compared to OSEM for high regularisation parameters. …”
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Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia by A. Pérez-Morenilla, A. Salazar, I. Failde, F. González-Sáiz, J.A. Micó

“…Results: In N = 111 patients, PSS were related to gender, rheumatic disease and anxiety, and worsened QoL. Anhedonia was detected in 93 patients (83.8%), with no significant gender differences in PSS. …”
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Workplace violence against physicians in Turkey’s emergency departments: a cross-sectional survey by Başak Bayram, Murat Çetin, Neşe Çolak Oray, İsmail Özgür Can

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Knowledge and Attitude of Pharmacy Students Regarding Timing of Prescribed Medicines Administration: Chronotherapy by Humayun Mirza, Ayesha Mansoor, Farheen Ahmad, Warda Idrees, Talmeez Zeb, Amir Naveed

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A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease by Samantha Mekhuri, Shirley Quach, Caroline Barakat, Winnie Sun, Mika L Nonoyama

“… # Conclusions More participants were negatively affected by extremes of weather: health status worsened, PA decreased, and frequency of exacerbations was higher compared to ideal. …”
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Effectiveness of Caregiver Intervention for Improving Medication Adherence on Level of Medication Adherence and Attitude toward Medications among Nonadherent Patients with Mental I... by Simrat Kaur, Renju Sussan Baby, Susanta Kumar Padhy

“…Background: Nonadherence to medication is the major challenge in treating mental illness, resulting in worsening symptoms and prolonging the course of the illness. …”
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Protective and anti-inflammatory effects of caffeic acid phenethyl ester on arsenic-induced vasculitis in vivo by Yasser Kofiah, Eman A.A. Abdallah, Mohamed F. El-Refaei

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