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2421
Changes in the Structural and Functional Albumin Properties in Patients with Decompensated Liver Cirrhosis
Published 2023-06-01“…To assess the structural and functional ability, serum albumin was analyzed by EPR spectroscopy.Results. Albumin levels within reference intervals were found in 37 patients (59.8 %). …”
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2422
The Cost of Regulating Effort: Reward and Difficulty Cues With Longer Prediction Horizons Have a Stronger Impact on Performance
Published 2025-01-01“…Across four experiments, we studied the effects of reward expectancy and task difficulty on effort expenditure in a perceptual decision-making task (random-dot-motion) and a cognitive control task (colour-naming Stroop), and within each task comparted cues between short (cueing the next trial) and long (cueing the next six trials) prediction horizons. …”
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2423
CHATGPT: ATTITUDES AND EXPERIENCES OF TECHNICAL UNIVERSITY STUDENTS IN UKRAINE
Published 2024-06-01“… Given the rising prevalence of AI tools within educational contexts, it is crucial to understand the dynamics of interacting with these technologies, their benefits and drawbacks. …”
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2424
From guideline to practice: three years of ICH S11 insights and recommendations
Published 2025-02-01“…Our review indicates that the implementation of ICH S11 facilitates science-driven discussions about the necessity and design of JAS within the broader non-clinical strategy. A thorough consideration of developmental aspects of the product’s pharmacological target, the clinical relevance of notable toxicity findings, and the clinical context of the medicine’s use fosters effective dialogue and improves regulatory alignment. …”
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2425
Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing
Published 2019-08-01“…Univariate sensitivity analysis was performed to examine the extent to which our calculations were affected by varying the parameters considered in our model within plausible extremes. To capture the interactions between multiple inputs, we also provided a probabilistic sensitivity analysis (PSA). …”
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2426
Implications of parental lifestyle changes and education level on adolescent offspring weight: a population based cohort study - The HUNT Study, Norway
Published 2018-08-01“…Objective Obesity tends to cluster in families reflecting both common genetics and shared lifestyle patterns within the family environment. The aim of this study was to examine whether parental lifestyle changes over time, exemplified by changes in weight and physical activity, could affect offspring weight in adolescents and if parental education level influenced the relationship.Design, setting and participants The population-based cohort study included 4424 parent-offspring participants from the Nord-Trøndelag Health Study, Norway. …”
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2427
Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies
Published 2024-05-01“…The high prevalence of atrophic gastritis emphasizes the importance of dynamic patient monitoring within cancer prevention programs.…”
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2428
Microstructural analysis and preliminary wear assessment of wire arc additive manufactured AA 5083 aluminum alloy for lightweight structures
Published 2025-01-01“…The results reveal that the microstructure consists of α-Al and β-(Al5Mg8) phases, with the Al5Mg8 phase distributed along grain boundaries and within grains. Notably, the grain size in the Y-direction (building direction) is larger than in the X-direction (deposition direction) due to temperature variations during processing. …”
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2429
Postnatal cytomegalovirus infection and its effect on hearing and neurodevelopmental outcomes among infants aged 3-10 months: A cohort study in Eastern Uganda.
Published 2025-01-01“…<h4>Methods</h4>This was a cohort sub-study within the BabyGel cluster randomised trial in Eastern Uganda. …”
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2430
Assessing SPECT/CT for the identification of cartilage lesions in the knee joint: A systematic review
Published 2025-03-01“…Objectives: To systematically assess the utility of SPECT/CT in the detection of chondral lesions within the knee joint, in patients presenting with knee pain, with or without structural change. …”
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2431
Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus
Published 2025-02-01“…Second-look arthroscopy was performed 12 months postoperatively, and the cartilage repair was assessed with the criteria of the International Cartilage Repair Society (ICRS). Results The within-group comparison showed significant improvements in pain severity and function in both groups post-treatment compared with pre-treatment. …”
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2432
“What does ‘often’ even mean?” Revising and validating the Comprehensive Autistic Trait Inventory in partnership with autistic people
Published 2025-02-01“…We validated the CATI-R within a large sample (n = 1439), comprising people with a self-reported autism diagnosis (n = 331), people who self-identified as autistic (n = 44), and non-autistic participants (n = 1046). …”
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2433
Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population
Published 2025-02-01“…This highlights the role of energy and carbohydrates in AIP within specific subgroups. Future research should focus on the effects of macronutrient combinations on AIP and long-term dietary impacts on metabolic health instead of BMI.…”
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2434
Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
Published 2025-02-01“…Conclusions The level of the available evidence introduced by primary studies hinder concluding the optimal needle characteristics; keeping the research question unanswered. However, within the limitations of the heterogenous studies, available data favors thinner needles for less pain during needle insertion; otherwise, data of the other outcomes was inconclusive. …”
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2435
Integrating phylogeographic and phenotypic evidence to delimit deep evolutionary lineages in the Dryophytes japonicus species complex, with an assessment of their conservation need...
Published 2025-02-01“…In this study, we assessed the genetic, genomic, morphological, and acoustic diversity and differentiation within the D. japonicus complex to propose taxonomic arrangements and assess taxon-specific threats for each defined clade. …”
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2436
The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders
Published 2025-02-01“…Rare neurodevelopmental disorders (NDDs) are one of the most significant unmet challenges in healthcare due to their lifelong nature, high management costs, and recurrence within families. This review will focus on newly-emerging genetic forms of NDDs resulting from variants in the glycine receptor (GlyR) α2 subunit gene. …”
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2437
Hospitalization outcomes in people living with HIV on Dolutegravir-based regimen in Mwanza, Tanzania: a comparative cohort
Published 2025-02-01“…The primary outcome was mortality within 3-months of hospitalization. Cox regression analysis was used to calculate hazard ratios to identify predictors of mortality. …”
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2438
DIGITAL AND NON-DIGITAL GAMES IN YOUNG LEARNER EFL CLASSROOMS AT WARTIME IN UKRAINE
Published 2024-10-01“…Findings revealed that in the current war-torn Ukraine most frequently preference is demonstrated for conventional games which are played within the structured environment of the English classroom. …”
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2439
Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center
Published 2024-03-01“…Even where trend data diverged (eg, for surgery \[43.1% likelihood of acceptance, 95% CI: 33.7%-52.8%\]), the cumulative surgery count over 5 years was within the margin of error of the real-world data. …”
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2440
Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects
Published 2025-02-01“…By gaining a deeper understanding of interactions between therapeutic antibodies, myeloma cells, and the tumor microenvironment (TME), it is hoped that previously unrecognized vulnerabilities within the disease may be revealed, paving the way to more effective treatment strategies.…”
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