Mechanism of action for Troxerutin targeting the sialylation-related gene EGLN3 for the treatment of LUAD by Yanan Wu, Yanlei Ge, Junqing Gan, Ye Jin, Yishuang Cui, Xuan Zheng, Xuemin Yao, Guogui Sun

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A review of UK publicly funded non-inferiority trials: is the design more inferior than it should be? by Nikki Totton, Steven Julious, Stephen Walters, Elizabeth Coates

“…Methods The International Standard Randomised Controlled Trial Number web registry and the National Institute for Health and Care Research’s Funding and Awards Library and Journals Library were searched using the term non-inferiority and logical synonyms. …”
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The clinical efficacy of proprioceptive neuromuscular facilitation technique in the treatment of scapulohumeral periarthritis: a systematic review and meta-analysis by Chengyu Zhu, Xueyan Huang, Jiaying Yu, Ying Feng, Haifang Zhou

“…Conclusion The PNF technique can help patients with scapulohumeral periarthritis to relieve pain, improve shoulder function, and strengthen daily living ability. In addition, a good psychological state is conducive to better recovery of patients ' health. …”
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Multi-omic integration of single-cell data uncovers methylation profiles of super-enhancers in skeletal muscle stem cells by Anyu Zeng, Hailong Liu, Shuling He, Xuming Luo, Zhiqi Zhang, Ming Fu, Baoxi Yu

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Intervention effect and mechanism of Dracocephalum moldavica L. extract on bleomycin-induced pulmonary fibrosis in rats by Xiaoyu SUN, Li CHEN, Ruifang GAO, Hui YU, Min JIN

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Research on ECG Signal Classification Based on Hybrid Residual Network by Tianyu Qi, He Zhang, Huijun Zhao, Chong Shen, Xiaochen Liu

“…Additionally, we rectify the class imbalance in the MIT-BIH Arrhythmia Database by applying the Synthetic Minority Oversampling Technique (SMOTE), therefore enhancing the model’s ability to detect infrequent arrhythmia types. …”
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Flood risk and property value changes: understanding the impact of climate event exposure in the context of population change by Sebastian Sandoval Olascoga, Evelyn Shu, Evelyn Shu, Jeremy Porter, Jeremy Porter

“…IntroductionExposure to flood risk has been linked to property value decreases, negative health/well-being, and both short and long-term population displacement. …”
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Involvement in medication safety behaviors among older people with chronic diseases: systematic review of intervention studies by Weixi Xu, Xiaoyan Lin, Huiqi Lai, Yaqin Ren, Hongjiang Ye, Ting Lin

“…Methods A comprehensive literature search across twelve databases was conducted using both computerized and manual methods. …”
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Biological activity of secondary metabolites of actinomycetes and their potential sources as antineoplastic drugs: a review by Sun Rui, Guo Fengrui, Zhang Yining, Shao Hong, Yang Xuewen, Wang Changping, Yang Chunjia

“…Actinomycetes are an important group of Gram-positive bacteria, renowned for their ability to produce a wide array of structurally diverse and biologically active secondary metabolites. …”
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Prediction of Treatment Recommendations Via Ensemble Machine Learning Algorithms for Non-Small Cell Lung Cancer Patients in Personalized Medicine by Hojin Moon, Lauren Tran, Andrew Lee, Taeksoo Kwon, Minho Lee

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Musculoskeletal Imaging for Low Back Pain in Direct Access Physical Therapy Compared to Primary Care: An Observational Study by Michael S Crowell, John S Mason, John H McGinniss

“… # Methods Military Health System Data Repository (MDR) data from January 2019 to May 2020 was reviewed for compliance with the low back pain HEDIS recommendation. …”
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Productivity Loss Related to Neglected Tropical Diseases Eligible for Preventive Chemotherapy: A Systematic Literature Review. by Edeltraud J Lenk, William K Redekop, Marianne Luyendijk, Adriana J Rijnsburger, Johan L Severens

“…<h4>Background</h4>Neglected Tropical Diseases (NTDs) not only cause health and life expectancy loss, but can also lead to economic consequences including reduced ability to work. …”
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The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis by Christos Stefanis, Christina Tsigalou, Ioanna Bezirtzoglou, Gregoria Mitropoulou, Chrysoula Voidarou, Elisavet Stavropoulou

“…IntroductionThe pandemic crisis is now a memorable milestone in the history of science, not only for the impacts on the population’s health but also for the effort of the medical community to find immediate solutions amid the pandemic so that appropriate therapeutic means can be provided. …”
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Effects of preoperative and postoperative resistance exercise interventions on recovery of physical function in patients undergoing abdominal surgery for cancer: a systematic revie... by David Stephensen, Ferhana Hashem, Kevin Corbett, Amanda Bates, Michelle George, Ralph Peter Hobbs, Malcolm Hopkins, Irena Hutchins, David Peter Lowery, Tracy Pellatt-Higgins, Charitini Stavropoulou, Ian Swaine, Lee Tomlinson, Hazel Woodward, Haythem Ali

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Association between stress hyperglycemia ratio (SHR) and long-term mortality in patients with ischemic stroke: a retrospective cohort study by Man Huang, Wan Wang, Dong-mei Ren, Yan-qing Chen, Ying Li, Yan Li, Wu-lin Li, Fei Wang

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Feasibility of a Web-Based and Mobile-Supported Follow-Up Treatment Pathway for Adult Patients With Orthopedic Trauma in the Netherlands: Concurrent Mixed Methods Study by Gijs J A Willinge, Jelle F Spierings, Kim A G J Romijnders, Elke G E Mathijssen, Bas A Twigt, J Carel Goslings, Ruben N van Veen

“…Anonymous data from a pre-existing database were used to compare health care resource use between the digital treatment pathways and traditional treatment. …”
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The efficacy and safety of stem cell therapy for ischemic stroke: a systematic review and network meta-analysis study by Wanpeng Chang, Xuejun Ma, Huawei Zhang, Hongli Xu, Shuai Liu, Binhong Du, Yanwen Xu, Yan Huang

“…Abstract Background and aim Using a network meta-analysis, this study evaluates the clinical efficacy and safety of different types of stem cell therapy in regard to the recovery of neurological function, motor function, and daily living ability in ischemic stroke patients. Methods A computerized search of the Cochrane Library, PubMed, Web of Science, Google Scholar, CNKI, and Wanfang Database was performed to collect randomized controlled clinical studies published from the time of library construction to December 2024, on the use of stem cells to improve function in patients with ischemic stroke. …”
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ERCC1/NGFR affects prognosis in basal-like breast cancer by Yuxi Lei, Xiabin Li, Fan Fan, Ruiwen Feng, Junfang He, Jing Zhong, Fancai Zeng, Yan Tang

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A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma by Anshun Wu, Fayin Liu, Lei Zhou, Runyi Jiang, Shangjiang Yu, Zihuan Zhou, Qi Zhang, Qian Zhang, Dongjie Jiang, Shaohui He, Haifeng Wei

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Effects of Physical Exercise Programs on Sarcopenia Management, Dynapenia, and Physical Performance in the Elderly: A Systematic Review of Randomized Clinical Trials by Renato Gorga Bandeira de Mello, Roberta Rigo Dalla Corte, Joana Gioscia, Emilio Hideyuki Moriguchi

“…Resistance training was the main intervention component in all included trials compared to inactive control groups (health education mainly). Physical training improved muscle strength, muscle quality, and muscle function compared to inactive control groups. …”
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